dyspnea orthopnea and pulmonary edema in pregnancy

... buffer Protein concentration was determined using the bicinchoninic acid (BCA) assay (Pierce, Rock-ford, IL, USA) The serine protease inhibitor aprotinin (Sigma) and the ACE inhibitor lisinopril ... To determine whether chymase is involved in cigarette smoking-induced pulmonary artery remodeling and PAH, chymase protein and mRNA levels in the lungs of the smoke-exposed hamsters and the control ... changes in pulmonary vascular and alveolar morphology and right ventricular systolic pressure (RVSP) (a) Representative hematoxylin and eosin (H&E) staining of small pulmonary vessels (original

Ngày tải lên: 12/08/2014, 11:21

... protein was calculated by the IOD ratio of the target protein to the housekeeping protein GAPDH, and the data were presented as percent-age of the control Immunostaining Immunostaining of laminin ... expression in tumor cells and endothelial cells in the infiltration area and in the necrotic center of GBM but an exclusive expression of PDCD10 in some pseudopalisading cells, indicating a distinct ... II Grade III Brain Edema *** Fig 5 The association of PDCD10 expression and the grade of brain edema in GBM a Grading peritumoral edema in GBM The grade of peritumoral edema in GBM was evaluated

Ngày tải lên: 22/09/2020, 23:45

... diet and physical activity interventions in pregnancy (13) The search was conducted in the CENTRAL, EMBASE, MEDLINE, Centre for Reviews and Dissemination, and the Cumulative Index to Nursing & ... Trang 1Variations in reporting of outcomes in randomised trials on diet and physical activity inpregnancy: a systematic review Ewelina Rogozińska,1,2 Nadine Marlin,3 Fen Yang,4 Jodie M ... ‘important’ maternal and fetal outcomes in studies on diet and physical activity-based interventions in pregnancy, the quality of reporting, and to assess the association of outcome reporting quality

Ngày tải lên: 20/10/2022, 17:55

... or non-invasive positive pressure ventilation or non-invasive ventilation or non-invasive ventilation) and (pulmonary edema or pulmonary oedema or congestive heart failure) and (clinical and trial ... characteristics and general quality criteria of randomized trials in acute cardiogenic pulmonary edema patients included in the study Reference Country and Setting Sample size Interventions Outcomes ... selection criteria are not reported Blinding: Yes: for articles that implemented blinding at any level No: for articles reporting not being able to implement blinding of interventions at any level Not

Ngày tải lên: 12/08/2014, 23:23

... therefore receive inadequate or no treatment Furthermore, duration and case fatality of tuberculosis are key parameters in interpreting epidemiological data Methodology and Principal Findings:To estimate ... tuberculosis in children - is even more uncertain, and insufficient data were identified to include it in our review An important limitation of using electronic databases going back in time is ... described in older publications, and many cases included in those studies would not meet modern diagnostic standards A large number of studies are based on passive case finding, which inevitably

Ngày tải lên: 29/03/2014, 03:20

... thiết gồm có dobutamine, dopamine và milrinone Dobutamine và dopamine là những thuốc có tác dụng hướng cơ dương tính (positive inotropic drugs) - Dopamine có tác dụng alpha nhiều hơn, đặc biệt ... Digoxin, được sử dụng trong điều trị suy tim sung huyết mãn tính, ít có vai trò trong điều trị phù phổi cấp - Các thuốc có tác dụng hướng cơ (inotropics) cần thiết gồm có dobutamine, dopamine ... tiểu đã thấy thế morphine trong điều trị phù phổi cấp - Nitrates được sử dụng dưới dạng sublingual nitroglycerin (NTG) (dưới lưỡi), topical NGT paste (thuốc dán), hoặc intravenous NTG drip (truyền

Ngày tải lên: 13/07/2014, 20:20

... use of medicinal plants is generally avoided during pregnancy, but once the infant is born, both mother and infant use a variety of medicinal plants During interviews the preparation and use of ... working in this field Materials and methods Study site The data presented here, are independent from [15], and were collected during three expeditions in June 2008; July 2009, and July 2010 in ... using the following general format: interviews were conducted in the homestead After introducing the research team and research objec-tives to the head of the village, an informal open-ended interview

Ngày tải lên: 10/08/2014, 09:21

... mainly by maternal first-time infection in the third trimester of pregnancy, have been published in literature Since the increasing prevalence of genital HSV infection and apparent increase in ... engineering, including live and inactivated whole virus vaccines and subunit vaccines consisting of recombinant viral glycoproteins in various adjuvants [72] Although animal studies on vaccination strategies ... threshold of infection, or if they prevent or improve disease They could reduce HSV2 incidence by preventing infection or by reducing the shedding or clinical recurrences in a HSV2-infected individual

Ngày tải lên: 12/08/2014, 04:21

... amino acid motif in their N-termini, chemokine ligands can be categorized into four types, C, CC, CXC and CX C The CXC chemokines contain two N-terminal cysteins separated by one amino acid, thus ... that inhibition of systemic CXCR4 through administration of AMD3100 will inhibit hypoxia-induced pulmonary hypertension and vascular remodeling in rats and that specific inhibition of the CXCR4 in ... in part pulmonary hypertension, vascular remodeling and right ventricular hypertrophy induced by chronic hypoxia in mice [27] However, the role of CXCR4 in pulmonary hypertension and remodeling

Ngày tải lên: 12/08/2014, 13:22

... clusters in a) the extracellular domain (exons 2-4) and b) the serine/threonine protein kinase domain (exons 9-11) Four mutations occurred in more than one independent patient/family: p.R491W and ... mutation Only in 3 out of the 22 families with HPAH (13.6%, Figure 3) examination of the BMPR2 gene (promoter and coding regions including flanking intronic regions) and the coding regions of ... species ESEfinder prediction Clinical classification according to family history p.A154G Transmembrane domain Disease causing conserved Not affected IPAH p.E386G Serine/threonine kinase domain Disease

Ngày tải lên: 12/08/2014, 13:22

... circulating levels and pulmonary expression of various inflammatory cytokines and chemokines including interleukin-1beta (IL-1β), IL-6, monocyte chemoattractant protein (MCP-1), RANTES, and fractalkine ... similar in IL-6+/+ and IL-6-/- mice Hypoxia exposure of IL-6+/+ mice led to marked increases in IL-6 mRNA and protein levels within the first week, with positive IL-6 immunostaining in the pulmonary ... determined using standard spectrophotometric techniques, and RNA integrity was assessed by visual inspection of ethidium bromide-stained denaturing agarose gels Protein extraction and ELISA Proteins

Ngày tải lên: 12/08/2014, 14:20

... and paraffin embedding, 5 µm-thick lung sections were cut and stained with hematoxylin-phloxine-saffron In each mouse, 30 intraacinar vessels accompanying alveolar ducts or alveoli were examined ... tissues, including lung tissue [1] Follow-ing bleomycin-induced injury in mice, mesenchymal stem cells colonized the lung and differentiate into type 1 or type II pneumocytes [2,3] In addition, ... liquid nitrogen After thawing at 0°C, the tissues were sonicated in 0.1 mM PBS containing antiproteases (1 µM leupeptin and 1 µM pepstatin A) and CHAPS (20 mmol/ L) and the homogenate was centrifuged

Ngày tải lên: 12/08/2014, 15:20

... AccessReview Invasive and noninvasive methods for studying pulmonary function in mice Thomas Glaab1, Christian Taube1, Armin Braun*2 and Wayne Mitzner3 Address: 1 Department of Pulmonary Medicine, III ... generally require anesthesia, intubation and expertise in handling Determination of pulmonary resistance (R L ) and dynamic compliance (C dyn ) in tracheostomized and mechanically ventilated mice ... obstruction during aerosol challenge with MCh, illustrating the decline in EF50 A and B, top tracings: pneumotachograph airflow signals A and B, bottom tracings: corresponding integrated VT signal

Ngày tải lên: 12/08/2014, 15:21

... cathepsin K in the lungs of mice is protective in bleomycin-induced pulmonary fibrosis Methods: Wild-type and cathepsin K overexpressing (cathepsin K transgenic; cath K tg) mice were challenged intratracheally ... lung function In addition, changes in cathepsin K protein levels in the lung were determined by immunohistochemistry, real time RT-PCR and western blotting Results: Cathepsin K protein levels were ... prepared and stained with hematoxy-lin/eosin (H/E) and Trichrome staining (Elastica-van-Gieson) The degree of lung fibrosis was determined according to the method described by Ashcroft and col-leagues

Ngày tải lên: 12/08/2014, 15:21

... phospholipids. In PMC the amount of choline plasmalogen (included in PC) and ethanolamine plasmalogen (included in PE) were 0.024 and 0.16 nmoles/mg proteins, respectively. In PMH3, these values increased ... in frac- tions 4 and 5 in control and in minor amount in fraction 7, while in hypoxia almost doubled in fractions 4 and 5. Lipid analysis in DRF Cholesterol was enriched in DRF in control (878 ... (0.25 M sucrose, 20 mM Tricine pH 7.4 and 40 µg/ml of the protease inhibitors aprotinin, chymosta- tin, leupeptin and antipapain), excised from the chest and immersed in ice cold solution 1. We

Ngày tải lên: 12/08/2014, 16:20

... richard.kraemer@insel.ch; David N Baldwin - dn_baldwin@hotmail.com; Roland A Ammann - roland.ammann@insel.ch; Urs Frey - urs.frey@insel.ch; Sabina Gallati - sabina.gallati@insel.ch * Corresponding author ... observed in CF remains incompletely explained and most likely reflects the influence of multiple, interrelated factors These may include differences in CFTR mutation and presence of infective ... between pulmonary hyperinflation and gas trapping and deterioration of lung function in CF are presented here using longitudinal data Previous investigations have demonstrated that pulmonary hyperinflation

Ngày tải lên: 12/08/2014, 16:20

... against oxidative stress in vitro and in vivo In addition to its physiological role in heme degradation, HO-1 may influence a number of cellular processes, including growth, inflammation, and ... expression increased in lung tissue in response to ovalbu-min aerosol challenge, indicating a role for HO-1 in asthma [70] In a similar model of aeroallergen-induced asthma in ovalbumin-sensitized ... of E-CO in lung dis-eases may reflect an increase in blood Hb-CO levels in response to systemic inflammation, as well as an increase in pulmonary HO-1 expression in response to local inflammation

Ngày tải lên: 13/08/2014, 13:20

... interstitial edema without septal lines 45 interstitial edema with septal lines 50 mixed interstitial and alveolar edema with some sparing of pulmonary region 55 mixed interstitial and alveolar edema involving ... perihilar and left lower lobar. The pulmonary regions are each scored using a semi-continu- ous scoring system consisting of 0 to 65 points. A score of 0 points indicates no signs of edema whereas ... of pulmonary edema Score (points) Edema severity scoring 0normal 10 mild pulmonary vascular congestion 20 moderate pulmonary vascular congestion 30 severe pulmonary vascular congestion 40 interstitial

Ngày tải lên: 13/08/2014, 20:22

... demonstrated an increase in mast cell numbers in the airways and have detected histamine, Prostaglandin D2 (PGD2), and tryptase in BAL fluid both in symptomatic asthma and after allergen inhalation ... demonstrates increased IgE, Th2- type cytokines, and eosinophilic inflammation thus making it difficult to evaluate the inter-relationship or importance of IgE in the induction of airway inflammation and ... oxygen and isoflourane were introduced It was manually restrained by gripping the skin over the back of the neck and holding it in a vertical position Using a micropipette 10µl of inoculum was introduced

Ngày tải lên: 03/10/2015, 21:57

... EVALUATION — Edema in adults can be divided into peripheral edema, pulmonary edema, ascites, and other forms of edema, which include lymphedema, nonpitting edema, and periorbital and scrotal edema Peripheral ... edema, including high-altitude pulmonary edema (HAPE), neurogenic pulmonary edema, and pulmonary edema related to opioid overdose (See "Noncardiogenic pulmonary edema".) hypertension in adults", ... "Clinical features and diagnosis of peripheral lymphedema".) Isolated pulmonary edema — Patients with pulmonary edema complain primarily of shortness of breath and orthopnea Physical examination

Ngày tải lên: 09/06/2019, 13:51