diseases of the liver and biliary tract

... Trang 1Sherlock’s Diseases of the Liver and Biliary System, Thirteenth Edition Edited by James S Dooley, Anna S F Lok , Guadalupe Garcia-Tsao and Massimo Pinzani © 2018 John ... and Rajiv Jalan 2 1 St Vincent’s University Hospital and University College, Dublin, Ireland D ch: BS Hoàng Nam 2 Liver Failure Group, Institute for Liver and Digestive Health, Division of ... 358: 2378–2387. Edited with the trial version of Foxit Advanced PDF Editor To remove this notice, visit: www.foxitsoftware.com/shopping Edited with the trial version of Foxit Advanced PDF Editor

Ngày tải lên: 17/11/2022, 16:00

... 1Infectious Diseases of the Head and NeckA variety of infectious diseases may involve head and neck structures These include bacterial, viral, fungal, and protozoal infections This article describes the ... sinus tracts that have a tendency to heal and recur Patients have a nodular mass at the angle of the jaw The masses gradually increase in size and number and form sinuses that open onto the face and ... times, and the incidence peaked in Europe in the 13th century The infec-tion usually affects superficial peripheral nerves, skin, mucous membranes, urinary tract, the eyes, and the testes, and disease

Ngày tải lên: 19/02/2014, 08:20

... Trang 1BỆNH GAN VÀ ĐƯỜNG MẬT ( LIVER AND BILIARY TRACT DISEASE ) Phần 2 24/ VAI TRÒ CỦA CHUP CỘNG HƯỞNG TỪ HẠT NHÂN ĐƯỜNG MẬT-TỤY (MAGNETIC ... tan sỏi (dissolution therapy) hay tán sỏi bằng các sóng sốc (shock-wave) trong cơ thể (bằng nội soi ) hay ngoài cơ thể 28/ MÔ TẢ HAI LOẠI TRỊ LIỆU LÀM TAN SỎI (DISSOLUTION THERAPY)? Liệu pháp ... Liệu pháp làm tan axit mật bằng đường miệng (oral bile acid dissolution therapy), thường với ursodeoxycholic acid (Ursofalk, Ursochol), dành cho những bệnh nhân với các sỏi mật nhỏ (thường <

Ngày tải lên: 13/07/2014, 16:20

... hepatocytes and facilitates the transport of organic anions bound to albumin, including bile salts and their conjugates and bilirubin, into the liver The restricted site of expression of OATP1B1 ... regulating the de novo synthesis of primary bile acids from cholesterol, expression of bile salts, and organic anion trans-porters in both hepatocytes and enterocytes, and in the re-sponse of the liver ... to new thera-peutic strategies for these widely different diseases in the future Mechanisms for hepatic bile formation The cellular organization of the liver combined with the unique endothelial

Ngày tải lên: 09/08/2014, 14:22

... structures that eventually bud off and migrate to the center of the portal tract to become the interlobular bile ducts The ductal plate cells around the periphery of the portal tract normally involute, ... process of differentiation from the hepatocytes at the margins of the portal tracts This differentiation results in the formation of the ductal plate, which is then remodeled by duplication and ... some degree of failure of the normal formation of the inter- lobular bile ducts, and results in a characteristic portal tract lesion consisting of persistence of some remnant of the ductal plate

Ngày tải lên: 09/08/2014, 14:22

... The right side of the brain is responsible for the motorand sensory functioning of the left side of the body and theopposite is true for the left-brain The left-brain is alsoresponsible for the ... beings due to the unique anatomy andphysiology of human nervous system Especially the cortex of the brain (the grey layer of the brain surface) is highlyevolved and complex Other organs of the human ... 25percent of the oxygen intake of the body and 70 percent of the total glucose available to the body The lower group of chordate animals do not have a developed organ like brainand therefore their

Ngày tải lên: 12/12/2016, 09:55

... The right side of the brain is responsible for the motorand sensory functioning of the left side of the body and theopposite is true for the left-brain The left-brain is alsoresponsible for the ... beings due to the unique anatomy andphysiology of human nervous system Especially the cortex of the brain (the grey layer of the brain surface) is highlyevolved and complex Other organs of the human ... 25percent of the oxygen intake of the body and 70 percent of the total glucose available to the body The lower group of chordate animals do not have a developed organ like brainand therefore their

Ngày tải lên: 01/04/2017, 10:41

... area, and the mass transfer coefficient of the membrane The latter is a function of the porosity and thickness of the membrane, the size of the solute molecule, and the conditions of flow on the ... activity of the basolateral Na+-K+ ATPase and Trang 14the number of Na+ channels in the apical membrane of the collecting duct In CKD, the excretion of the dietary load of potassium occurs at the ... NaPi2a and NaPi2c on the apical and basolateral membranes of the renal tubule FGF-23 also reduces the ability of the kidney to generate 1,25(OH)2D3 In the parathyroid gland, the FGF-23 receptor, the

Ngày tải lên: 26/05/2017, 22:35

... pneumocytes and some bronchiolar cells of the transgenic animals, and thereby promotedthe development of carcinoma of the lung This mouse model should prove useful to thestudy of lung carcinogenesis and ... adenocarcinomas of the lung These mu‐tations result in prolonged activation of the receptor and downstream signaling throughphosphorylated Akt, in the absence of ligand stimulation of the extracellular ... increased traffic across the continents and migration of thepopulation Physicians need to be aware of the symptoms and imaging findings of thesediseases mainly in travelers and immigrants from tropical

Ngày tải lên: 23/03/2014, 14:20

... Binding of TGF-β ligands to their tetrameric type I and II receptors causes sequential activation of MKK-4/JNK and the complex of Smad 2/3 and Smad 4 proteins (Figure 2) This complex can enter the ... Healing and fibrotic scaring are advantageous in wounds, but they can be pathological in the kidneys, the lungs and the liver [1] Extensive investigations in mice, rats, and man of acute and chronic ... independent and dependent pathways; they recruit and stimulate T cells and monocytes by the production of chemokines, especially IL-6 and SDF-1 (CXCL12) and they can attract and retain B lymphocytes by

Ngày tải lên: 09/08/2014, 08:22

... to the skin into the liver substance and extracted This is the quick part of the procedure The tip of the needle is now placed on sterile paper and some of the remaining saline flushed through the ... Anatomy of the biliary tract, Development of the liver and bile ducts, Anatomical abnormalities of the liver, Surface marking, Methods of examination, Hepatic morphology, Electron microscopy and ... to a compartment of uncoupling of receptor and ligand (CURL) The receptor and ligand separate The receptor returns to sinusoidal plasma membrane and the ligand enters a lysosome and is degraded...

Ngày tải lên: 10/08/2014, 15:20

... especially the hypothenar and thenar eminences and pulps of the fingers (fig 6.12) Islets of erythema may be found at the bases of the fingers The soles of the feet may be similarly affected The mottling ... diameter and is not obliterated by pressure Venous stars are seen on the dorsum of the foot, legs, back and on the lower border of the ribs Palmar erythema (liver palms) The hands are warm and the ... benzodiazepines and barbiturates (fig 7.9) The binding of any of these ligands opens a chloride channel and after the influx of chloride there is hyperpolarization of the postsynaptic membrane, and neuroinhibition...

Ngày tải lên: 10/08/2014, 15:20

... veins of the caval system Deviation of blood into these channels leads to varicosities in the submucous layer of the lower end of the oesophagus and fundus of the stomach (b) At the anus, the superior ... bypass the block and return blood towards the liver These enter the portal vein in the porta hepatis beyond the block They include the veins at the hilum, venae comitantes of the portal vein and ... by the union of the superior mesenteric vein and the splenic vein just posterior to the head of the pancreas at about the level of the second lumbar vertebra It extends slightly to the right of...

Ngày tải lên: 10/08/2014, 15:20

... one another to form septal bile ducts and so on until the two main hepatic ducts emerge from the right and left lobes of the liver at the porta hepatis Small bile ducts distal to the canals of Hering ... with other variations of the A(TA)nTAA allele have also shown elevated serum total bilirubin levels, including the alleles 5/6, 5/7 and 7/8 [5] In Asians and the Japanese, the frequency of the ... micrograph of the canalicular biliary system porters, from the microsomes to the bile canalicular membrane The peri-canalicular cytoplasm contains elements of the cytoskeleton of the hepatocyte:...

Ngày tải lên: 10/08/2014, 15:20

... serum IgG anti-HDV is found There may be a window period between the disappearance of one and the detection of the other Loss of IgM anti-HDV confirms the resolution of HDV infection, whereas persistence ... both as monotherapy, and, on the basis of recently completed large trials, in combination with ribavirin The cost and availability makes all these treatments out of reach of the millions of sufferers ... introspection by the patient Antiviral therapy The aim is to control infectivity, eradicate the virus and prevent the development of cirrhosis However, permanent loss of HBeAg and HBV DNA are unusual and...

Ngày tải lên: 10/08/2014, 15:20

... lipids synthesized in the liver itself The origin depends upon the dose of ethanol ingested and the lipid content of the diet After an acute, isolated ingestion of a large dose of ethanol the fatty ... redox state of the liver The hydrogen generated replaces fatty acid as a fuel and is followed by triglyceride accumulation and fatty liver The redox state of the liver changes, protein synthesis is ... related to the severity of the liver disease [72] The extent of the nutritional defect depends on the type of alcoholic, whether of low socioeconomic status where protein-calorie malnutrition often...

Ngày tải lên: 10/08/2014, 15:20

... throughout the world except in New Zealand, Australia and some parts of the west Pacific The Borrelia multiply in the liver, invading liver cells and causing focal necrosis Just before the crisis the ... abscess in the left lobe of the liver may show a crescentic deformity of the lesser curve of the stomach US is the most useful (fig 29.7) CT shows the abscess with a somewhat irregular edge and low ... the liver parenchyma The lesions produced are single or multiple and of variable size The amoebic abscess is usually about the size of an orange The most frequent site is in the right lobe, often...

Ngày tải lên: 10/08/2014, 15:20

... softening of secondary malignant growths also occur Congenital anomalies of the biliary tract The liver and biliary tract develop from a bud-like outpouching of the ventral wall of the primitive ... laterally over the gallbladder down to the duodenum, to the hepatic flexure of the colon and even to the right lobe of the liver, perhaps closing the foramen of Winslow In a milder form, a band of tissue ... anomaly the gallbladder lies under the left lobe of the liver, to the left of the falciform ligament This may be caused by the gallbladder migrating to a position under the left lobe of the liver...

Ngày tải lên: 10/08/2014, 15:20

... usually used The left lobe of the donor liver is excised and the right lobe anastomosed to the portal vein, inferior vena cava and aorta of the recipient The donor liver hypertrophies and the recipient’s ... into the liver They cause complete obstruction of the extra-hepatic bile ducts with intra-hepatic biliary dilatation and enlargement of the liver The gallbladder is collapsed and flaccid If the ... which there is no acceptable, alternative therapy The patient and the family must understand the magnitude of the undertaking and be prepared to face the difficult early postoperative period and...

Ngày tải lên: 10/08/2014, 15:20

... cầu hình cầu (spherocytosis) có khả bị sỏi sắc tố (pigment stones) 9/ BÙN MẬT (BILIARY SLUDGE) LÀ GÌ? Bùn mật (biliary sludge) cấu tạo chất kết tủa vi thể cholesterol hay calcium bicarbonate ... khí thấy trường hợp bất túc huyết quản Thường xảy nơi đàn ông bệnh nhân bị đái đường thường kèm theo nhiễm khuẩn huyết (sepsis) 2/ CÓ PHẢI TẤT CẢ CÁC SỎI MẬT ĐỀU GÂY ĐAU? CÓ PHẢI VIỆC KHÔNG CÓ ... nên triệu chứng y hệt triệu chứng gây nên sỏi túi mật Bùn mật (sludge) liên kết với đau quặn gan (biliary colic), viêm tụy tạng, viêm mật quản (cholangitis), viêm túi mật (cholecystitis) Bùn mật...

Ngày tải lên: 13/07/2014, 16:20