diffusion controlled drug delivery systems

... phase-change polymersfor ocular drug delivery Adv Drug Delivery Rev 16:45–50, 1995 4 Salminen, L., and Urtti, H Prolonged pulse-entry of pilocarpine with a ble drug insert Graefes Arch Clin Exp ... non–cross-linked type, therebyprolonging drug delivery times They concluded that cross-linked collagenshields might be useful ocular drug delivery devices because they can allowdrug concentrations to achieve ... the efficacy andtoxicity of these carriers as delivery agents/carriers for ocular drug delivery The enhancement effect of Pz-peptide on permeability of drug acrossthe cornea and conjunctiva was studied

Ngày tải lên: 10/08/2014, 00:20

... Ocular drug delivery Mechanism(s) of corneal drugtransport and mucoadhesive delivery systems, S.T.P Pharma, 5:839 11 Mikos, A G., and Peppas, N A (1986) Systems for controlled release ofdrug V ... favorable characteristicfor a preferred pharmaceutical drug delivery system Trang 14II PARTICULATE SYSTEMS IN OCULAR DRUG DELIVERYA Topical Systems The isolation of the vitreous caused by the blood-retinal ... Microparticulates for ophthalmic drug delivery J Ocul.Pharmacol., 10:29 15 Joshi, A (1996) Microparticulates as an ocular drug delivery system In:Ocular Therapeutics and Drug Delivery, I K Reddy (ed.)

Ngày tải lên: 10/08/2014, 03:20

... (2000) Bispecific Mab aided liposomal drugdelivery J Drug Target, 8(4):257–266 160 Cristiano, R J., and Roth, J A (1995) Molecular conjugates: a targeted genedelivery vector for molecular medicine ... perform and bypasses the needfor complex viral or non viral delivery systems Subretinal or intravitrealinjections are common routes of delivery to the affected area Preparativeamounts of neurotrophic ... ther-apeutically active drugs This is a fascinating technology that has the poten-tial of being a tailor-made delivery system that will improve the therapeuticindex of a number of drugs mod-Another

Ngày tải lên: 10/08/2014, 03:20

... oligonucleotide therapeutics: drug deliveryand targeting Adv Drug Delivery Rev., 18:115–131 167 J W Jaroszewski, and J S Cohen (1991) Cellular uptake of antisense godeoxynucleotides Adv Drug Delivery Rev., ... Section 201(p)) New drugs require INDs for conductingclinical investigations and NDAs for marketing approval The terms drugand new drug are inclusive of the drug substance and the drug product It ... approved drug 9 Radiation sterilization is used for a drug product (21 CFR200.30) Trang 26C Combination Drug and DeviceIt is possible to have as a new ophthalmic delivery system a combination of a drug

Ngày tải lên: 10/08/2014, 03:20

... nanocapsule delivery system to investigate the capacity of temporal release of antiangiogenetic drug and anticancer drug in vitro We found that the drug release profiles of the encapsulated drugs, ... Z., Chui WK., Ho PC Integrin targeted drug and gene delivery Expert opinion on drug delivery 2010; 7(2), 159-171 5 Wang Z., Chui WK Ho PC Nanoparticulate delivery system targeted to tumor neovasculature ... induction by the combined drugs To establish the hypothesis on the advantage of having temporal delivery of antiangiogenesis and anticancer drugs with our nanoparticulate delivery Trang 11surface

Ngày tải lên: 11/09/2015, 09:58

... SEMINAR REPORT OF DRUG DELIVERY SYSTEMS Topic: Hydrogels as Drug Delivery Systems Reporter: Nguyen Van Tu Supervisor: Dr Le Thanh Dung Dr Ha Cam ... topic of drug delivery In the drug delivery topic, the search for subtopics of proteins and genes resulted in 1674 and 284 references, respectively - S C Lee, I K Kwon and K Park, Adv Drug Delivery ... HOOK INTRODUCTION Various Systems to be applied Attract much attention DDSs Hydrogels: worth concerning Each System possesses particular characteristics DDSs: Drug Delivery Systems SOME FIGURES The

Ngày tải lên: 07/06/2017, 14:46

... release of drugs in conventional drug delivery systems (CDDSs) have led to the development of smart nanocarrier-based drug delivery systems, which are also known as Smart Drug Delivery Systems (SDDSs) ... Site-specific drug delivery led to a keen interest in the SDDSs as an alternative to chemotherapy Smart nanocarriers, nanoparticles used to carry drugs, are at the focus of SDDSs A smart drug delivery ... gene delivery with higher transfection efficiency [109] Hsiao et al designed and constructed a MSN-based theranostic drug delivery sys-tem which can be used for cancer imaging along with drug delivery

Ngày tải lên: 15/01/2020, 17:52

... result in the drug having low bioavailability, making the preparation of self-microemulsifying drug delivery systems rational Besides, the amine group in the molecular structure of the drug (Fig ... and sev-eral other herbal drugs such as curcumin (Zhang et al., 2012), silymarin (Wu et al., 2006) or baicalein (Liu et al., 2012) Self microemulsifying drug delivery systems (SMEDDS) has been ... the drug release was not quite suitable for SMEDDS In this study, the drug diffusion through dialysis membrane was used for the investigation However, the driving force of drug diffusion was controlled

Ngày tải lên: 20/01/2020, 07:31

... increase drug delivery efficacy and reduce side effects, and to improve the drug therapeutic effect by controlling the rate of drug delivery Hydrogel-based contact lenses were used to prepare local drug ... and their potential uses as drug delivery carriers have also been reported in recent research [8 10] Ophthalmic drug delivery via PHEMA contact lenses could improve the delivery efficiency by increasing ... Barriers to glaucoma drug delivery J Glaucoma 17(2):147–156 5 Bengani LC, Hsu KH, Gause S, Chauhan A (2013) Contact lenses as a platform for ocular drug delivery Expert Opin Drug Del 10(11):1483–1496

Ngày tải lên: 29/05/2020, 15:16

... Hollow Beads for Controlled Drug Delivery Trang 3Cellulose-Coated Chitosan Hollow Beads for Controlled Drug Delivery Trang 4Cellulose-Coated Chitosan Hollow Beads for Controlled Drug Delivery Trang ... gastrointestinal tract Along with many applications in local and systemic delivery of drugs, the colon-specific drug delivery systems can delay the absorption for the treatment of diseases that exhibit ... overnight The maximum amount of drug that can be dissolved in reverse micelles varies from drug to drug and has to be determined by gradually increasing the amount of drug until the clear microemulsion

Ngày tải lên: 11/07/2021, 16:35

... aspects in the development of osmotically controlled oral drug delivery systems J Control Release 2002;79:7-27. 3 Joseph RR, Lee HL Controlled Drug Delivery: Fundamentals and Applications 2 nd ... including prohibitive cost of developing new drug entities, expiration of existing patents, etc., Controlled delivery systems provide a uniform concentration of drug at the absorption site and thus after ... for providing SEM facility. REFERENCES 1 Jerzeweski RL, Chein YW Osmotic drug delivery, in treatise on controlled drug delivery Fundamentals, Optimization, Applications 1 st ed New York: Marcel

Ngày tải lên: 01/11/2022, 09:54

... NP composites for drug delivery systems 6 Selected studies on chitosan films for drug delivery systems Chitosan was also used in the preparation of films for drug delivery systems[85e87] Films ... Trang 33 Drug delivery properties of chitosan3.1 Anionic drug delivery properties When a technique of drug discharge cannot be achieved by using a simple drug dissolution process such as diffusion, ... promising agent for drug delivery systems This review summarizes the biomedical application of chito-san and chitochito-san-based NP composites with emphasis on drug delivery systems Chitosan is

Ngày tải lên: 02/11/2022, 11:37

... dosage/delivery systems An ideal drug delivery system should pose two important elements: controlled and targeted delivery In this regard, NPs have emerged as the potential and effective drug delivery systems ... Antimicrobial Drug Delivery Over the last few decades, considerable studies have been done on the development of new drug delivery system to overcome the limitations caused by the conventional dosage/delivery ... infections The review also focused on the development of nanoparticle systems for antimicrobial drug delivery and use of these systems for delivery of various antimicrobial agents, giving an overview

Ngày tải lên: 04/12/2022, 15:47

... transdermal drug delivery systems and revealed their implications over the other administration routes PLGA-based transdermal drug delivery systems PLGA-based microneedles for transdermal drug delivery ... routes, including intravenous drug delivery, pulmonary drug delivery, transdermal drug delivery, etc Further to enhance the loading efficiency and specificity of the drug delivery carrier, PLGA surface ... desired drug dosage and the therapeutic window is one of the primary criteria to be considered while designing drug delivery systems (DDS) By employing nanomaterials as a base for drug delivery

Ngày tải lên: 04/12/2022, 15:56

... proposed the classic concept of drug delivery by a carrier that would transport therapeutic drugs specifically to the target organ17 Since then, numerous drug delivery technologies have been ... particles and anti-cancer drugs have been investigated16, but drugs may be rendered therapeutically ineffective by heat-induced degradation The key objective of drug delivery is to increase the ... Trang 1Simultaneous hyperthermia-chemotherapy with controlled drug delivery using single-drug nanoparticles Itaru Sato1,2, Masanari Umemura1, Kenji Mitsudo2, Hidenobu

Ngày tải lên: 04/12/2022, 16:11

... of the drug delivery system (See Figure 2.5b) a Drug Drug Drug- loaded biodegradable particles b Drug Drug Drug- loaded biodegradable particles Figure 2.5 The polymer degrades to release drug molecules ... to small molecular drug IBU, the fabrication of controlled drug delivery system for large protein model drug BSA is more complicated, as it involves not only the properties of drug matrix itself ... area of drug delivery which is due to the underlying principle that drug delivery technology can bring both commercial and clinical values to healthcare products The innovative drug delivery...

Ngày tải lên: 13/09/2015, 19:46

... for Drug Delivery Systems Drug delivery systems modify the kinetics or the location of the escape of the drug from the medicine Tables 15.1 and 15.2 provide generic reasons for using drug delivery ... numerous types of protein drug [21–23] 15.6 Examples of Biodegradable Polymer Drug Delivery Systems Under Development 15.6.1 Polyketals Polyketal-based drug delivery systems are under development ... nanotechnology and biological mimicry to create drug delivery systems that penetrate into 15.6 Examples of Biodegradable Polymer Drug Delivery Systems Under Development articular cartilage tissue...

Ngày tải lên: 25/10/2013, 08:20

... to advanced drug delivery systems Chemical Aspects of Drug Delivery Systems Table Mechanisms and properties influencing drug release from particle carrier systems* MECHANISM OF DRUG RELEASE ... stability Chemical Aspects of Drug Delivery Systems Table Routes of administration and general classification of drug delivery systems ROUTES OF ADMINISTRATION DRUG DELIVERY CLASS ORAL SOLIDS (e.g ... Materials and Systems for Drug Delivery and Targeting Table 5A Formulation systems for controlled drug release and drug targeting ORAL,ROUTE ADMINISTRATION ROUTE FORMULATION SYSTEM ORALCONTROLLED...

Ngày tải lên: 28/03/2014, 10:20

... Generalities of drug delivery Liposomes as drug delivery systems Polymers and polymeric systems for drug delivery Dendrimers for drug delivery GENERALITIES OF DRUG DELIVERY DRUG DELIVERY SYSTEM ... Targeted drug delivery systems: deliver drug to a desired body location, organ, tissue, specific cells…  Controlled- release drug delivery systems: preprogramed drug release By the route of delivery: ...  Topical (local) drug delivery systems: drugs are delivered locally to the target organ/tissue without entering the systemic circulation  Systemic drug delivery systems: drugs are delivered...

Ngày tải lên: 18/04/2014, 15:37

... define drug- delivery systems of a certain size range Reflecting this trend of size definition, Nanoparticulate Drug Delivery Systems is a worthy attempt to bring together a wide range of drug- delivery ... and their delivery to where they are needed An ever increasing number of drug- and vaccinedelivery systems are being tested clinically, with many already marketed Recently, drug- delivery systems ... 0‑8493‑9073‑7 (alk paper) Drug delivery systems Nanoparticles I Thassu, Deepak II Deleers, Michel III Pathak, Yashwant IV Series [DNLM: Drug Delivery Systems ‑methods Nanostructures Drug Carriers W1 DR893B...

Ngày tải lên: 04/06/2014, 14:47