development of a scaffold for bone tissue engineering

... field of tissue engineering has shown to be a promising alternative in using cell transplantation as a strategy to achieve tissue repair and regeneration for a variety of therapeutic needs One approach ... developed apparatus for the application of uniaxial strain of cell-seeded constructs Uniaxial cyclic loading via a piston was used to generate a cyclic traction reactor for the long-term culture of ... culture dish and lead screw are attached to an aluminium baseplate with a polycarbonate dust cover and can be installed in a suitable laboratory incubator Trang 35Figure 2.2 Schematic of the cell...

Ngày tải lên: 04/10/2015, 10:25

... Trang 1 DEVELOPMENT OF A BIOREACTOR FOR IN-VITRO ENGINEERING OF SOFT TISSUES KYAW MOE NATIONAL UNIVERSITY OF SINGAPORE 2005 Trang 2 DEVELOPMENT OF A BIOREACTOR FOR IN-VITRO ENGINEERING ... engineering offers the possibility of replacing damaged human tissue with functional neotissue (engineered tissue) with similar mechanical and functional characteristics One approach of tissue engineering ... section of tubular form scaffolds and sheet form scaffolds after two weeks of cyclic straining; (a & c) Strained samples, (b& d) Unstrained sample 38 Figure 4.2 (a) Spool assemble parts,...

Ngày tải lên: 04/10/2015, 15:46

... Chandra Nath, Ahsan Habib, Afzal, Aravind, Asma, Anower, Zakaria, Abdul Hannan, Abu Taiyob and many more for Trang 5iii Table of Contents Acknowledgements i Table of contents iii Summary ... Trang 1IMPROVING THE MECHANICAL AND FUNCTIONAL PERFORMANCE OF EXTRUSION-BASED ADDITIVE MANUFACTURED SCAFFOLDS FOR BONE TISSUE ENGINEERING MUHAMMAD TARIK ARAFAT NATIONAL UNIVERSITY OF SINGAPORE ... cancellous bone grafts has become a key priority in bone TE [5-7] In scaffold-based bone TE the scaffold acts as a platform to carry cells or therapeutic agents for regenerative therapies An ideal scaffold...

Ngày tải lên: 10/09/2015, 15:51

... Wong and S H Teoh “Surface modification of PCL-TCP scaffolds in rabbit calvaria defects: Evaluation of scaffold degradation profile, biomechanical properties and bone healing patterns” Journal of ... improve interfacial mechanical interlock and enhance early bone formation: An in vitro and in vivo characterization” Journal of Biomedical Materials Research: Part A v 92A, p 311-321 (2010) A Yeo, ... degradation will commence The rate of chain scission and weight of polymer decreases as a result of the formation and removal of short chains of oligomers from the scaffold matrix Fragmentation of...

Ngày tải lên: 09/10/2015, 11:18

... This part serves as an initial stage of a larger project, in order to develop a scaffold of a higher porosity that allows for a more rapid degradation whilst maintaining favourable mechanical properties ... of implantation of autografts and PCL-TCP scaffolds for individual micropigs 99 Figure 5.14 The average values of bone volume fraction detected after 6 months of implantation of autografts and ... limitations have then instigated new research aiming to provide a bone graft engineered in the laboratory and readily available The ultimate goal of this approach was the regeneration rather than...

Ngày tải lên: 09/10/2015, 11:18

... dwi-lapisan yang sangat baik berbanding dengan perancah lapisan tunggal Sifat mekanikal serta nilai anggaran tekanan pecah bagi perancah penyejukbekuan bertambah baik dengan ketara selepas proses ... tidak memberikan kesan yang ketara ke atas sifat-sifat mekanik perancah Tambahan pula daya tahan sel menunjukkan kesan yang positif dimana ini menandakan salutan kolagen telah memberi kesan yang ... sifat-sifat yang sangat baik pada keadaan optimum iaitu pada nisbah 6:1 bagi PLCL kepada zarah natrium klorida (NaCl) Span kolagen yang disalut pada perancah silinder PLCL melalui kaedah pengeringan...

Ngày tải lên: 27/01/2021, 11:08

... for RT-PCR were: for the I7 OR (5¢-CGTCAAGGAGAAAAAACCCCGGATCT AAAAAATGGAGCGAAGGAACCACAG-3¢) and (5¢-AG CTGCCTGCAGGTCGACTCTAGAGGATCCTAACCAA AAAAAACCCCGGATCTAAAAAATGGAGCAGAAAC CCTGCAGGTCGACTCTAGAGGATCTCAAGCCAGT ... CCCGGATCTAAAAAATGGAGCAGAAACTCATCTC TGAAGAGGATCTG-3¢) and (5¢-GCATGCCTGCAGG TCGACTCTAGAGGATCTCAAGCCAGTGACCGCCT CCC-3¢), and checked for the presence and sequence of the new insert, as in the case of ... Trang 8activity By taking advantage of structural and func-tional similarities between yeast and mammalian GPCR signaling pathways, this assay enables the quantitative measurement of receptor activity,...

Ngày tải lên: 07/03/2014, 16:20

... Accreditation of Laboratory Animal Care International Mouse adaptation The general approach to adapt MARV to mice was based on virus passage in scid (BALB/c background) mice to avoid usage of suckling ... filoviruses, Ebola (EBOV) and Marburg (MARV), cause a lethal hemorrhagic fever Human isolates of MARV are not lethal to immmunocompetent adult mice and, to date, there are no reports of a adapted MARV model ... develop a lethal mouse-adapted Marburg virus The goal was to isolate the viral population that was capable of migrating to target tissues/ organs (i.e., liver) at the earliest time point Each group...

Ngày tải lên: 18/06/2014, 18:20

... however the explanation in this section also applies to other types of antenna polarization The original antenna of a Mica2 mote is a standard one-quarter wavelength monopole antenna with 17 cm-length ... in a WUSN testbed orientation Naturally, for every combination of sensor node type and its antenna, different antenna polarizations and orientations can be adopted as the default configuration for ... use of the well known Friis equation related to the free space propagation model However, the application of this equation assumes the availability of detailed information about the antennas gain/losses,...

Ngày tải lên: 21/06/2014, 23:20

... perform a critical role in all aspects of tissue homeostasis [38] Quiescent ECs can generate an active antithrombotic and anti-platelet surface to facilitate the transit of plasma and cellular ... applications of NO, and approaches for controlled release of NO Literature reviews on gelatin-siloxane nanoparticles (GS NPs), PVA and PCL materials and the relevant fabrication techniques are also ... more than half a million coronary artery bypass grafts are Trang 20implanted [6] Autologous vascular grafts such as mammary artery and saphenous vein segments harvested from the patient, are considered...

Ngày tải lên: 10/09/2015, 09:08

... that of a typical application context of a CAD framework Instead of identifying all aspects of the analogy between them, the focus was placed on characterizing the relationship among a group of ... transportable among the participating agents in such a way that the intents and concerns of each are neither lost nor unaddressed Features are seen by many researchers as the natural and most appropriate ... one can also observe a large number of later yet almost parallel efforts to integrate all the related data, sub-processes, activities, tools and resources so as to automate the process as a whole...

Ngày tải lên: 15/09/2015, 17:09

... Trang 1APATITE BASED MICROCARRIERS FOR BONE TISSUE ENGINEERING APPLICATIONS ! FENG YONG YAO, JASON NATIONAL UNIVERSITY OF SINGAPORE 2015 Trang 2APATITE BASED MICROCARRIERS FOR BONE TISSUE ENGINEERING ... Microsphere!Preparation! !47! CHAPTER 3 FABRICATION AND CHARACTERISATION OF APATITE MICROCARRIERS 3.1! Introduction 49! 3.2! Materials and Methods 50! Trang 93.2.3! Characterisation!of!apatite!microcarriers! ... Figure 2.1 Hierarchical nature of bone[11] Trang 25Chemically, bone is composed of an organic phase consisting of mainly collagen (35% dry weight) and a mineral phase of carbonated apatite (65%...

Ngày tải lên: 22/09/2015, 15:18

... Criteria for evaluating competency are stated as “The charts selected are the largest scale suitable for the area of navigation and charts and publications are corrected in accordance with the latest ... recording and information management capabilities of ECDIS, as well as considering the presentation of othernavigational information, such as radar and AIS ‘O VER R ELIANCE ON ECDIS’ is a subject matter ... the area of navigation and charts and publications are corrected in accordance with the latest information available” In Section B-II/1 (Assessment of abilities and skills in navigation watchkeeping),...

Ngày tải lên: 09/05/2016, 16:54

... because of thermal expansion of the sea and reduction of ice and snow cover, as well as permafrost In addition, global warming is affecting the patterns and quantities of precipitation (rain and ... effectiveness of a CO2 supply chain network in mitigating emissions for the whole of Germany The results indicate that a carbon-based supply chain in Germany can be profitable with an annual profit of 162.21 ... therefore, aims at the development of a general framework that deals with a broad range of problem types and aid design engineers and decision-makers in quickly assessing different scenarios at...

Ngày tải lên: 28/02/2021, 21:36

... statistical software was used for analysis The data were expressed as mean ± standard deviation The analysis of variance (ANOVA) was used for group com-parison, and post hoc test was used for ... construct.As for the bioma-terials scaffold, the shape of the scaffold must be con-trolled and customized Three-dimensional scaffolds made of biomaterials such as nano-hydroxyapatite-polyamide 66 (nHA-PA ... as a vascular carrier and incorpor-ation of biomaterials and cells or growth factors into them is advantageous, as it allows for instantaneous perfusion after the graft is implanted, which can...

Ngày tải lên: 25/05/2021, 22:08

... physical features such as rivers, mountains and roads on maps A GIS also facilitates the display of tabular data such as demographics by attaching the data to a set of coordinates (Pratt & ... Gaming Association - AGA (2006) State of the States: the AGA survey of casino entertainment Washington, DC: American Gaming Association California Center for Native Nations - CCNN (2007) An impact ... easy viewing of the data for destination marketers and planners Travel patterns are the spatial component of a vacation and provide a conceptual framework to study visitor behavior Travel patterns...

Ngày tải lên: 08/01/2022, 09:37

... in AI projects offers significant advantages by efficiently managing unstructured data, facilitating horizonta l scalability for handling large volumes of data, and enhancing flexibility and ... and performance in data storage, retrieval, and processing Based on the analyses provided, Firebase Realtime Database by Google will be chosen for this project Trang 19SERVER AND DATABASE Table ... we establish a connection to the local WIA device manager by creating an instance of the IWiaDevMgr2 (Windows Image Acquisition Device Manager) object After that, we enumerate information about...

Ngày tải lên: 26/09/2024, 12:11

... Evaluation of a Polycaprolactone Based Bioresorbable Scaffold for Bone Regeneration at Load Bearing Sites 5th International Conference on Materials for Advanced Technologies (ICMAT) Symposium A: ... supporting the attachment, proliferation and differentiation of primary mammalian bone marrow stromal cells Cells remained viable and metabolically active through the 28-day study As degradation and resorption ... soft tissues of the body Specific hard and soft tissues (bone, cartilage, muscles, tendons and ligaments) also form a system of mechanical levers for generation and transfer of forces to achieve...

Ngày tải lên: 11/09/2015, 09:58

... degradation (ERAD), and degraded by the pro-teasome As a major intracellular calcium storage com-partment, the ER also plays a critical role towards maintenance of cellular calcium homeostasis In addition, ... Nakatani Y, Kaneto H, Kawamori D, Yoshiuchi K, Hatazaki M, Matsuoka TA, Ozawa K, Ogawa S, Hori M, Yamasaki Y, Matsuhisa M (2005) Involvement of endoplasmic reticulum stress Obesity IR Inflammation ... receptor-associated factor-2) and ASK1 This leads to activation of ASK1 and JNK, followed by apoptosis, and (3) activation of the ER localized cysteine protease, caspase 12 Caspase 12 is activated by m-Calpain...

Ngày tải lên: 02/11/2022, 09:29

... nonlinear system of partial differential equations The system also has a large time delay because of the slowness of the heat exchange The goal of the paper is to develop a controller that will maintain ... deploying the displacement ventilation HVAC system Zhicheng Li1, Ramesh K Agarwal1, Huijun Gao2 1 Department of Mechanical Engineering and Materials Science, Washington University in Saint Louis, ... simulated the exterior surface and was assumed to be at a constant value of 320K A 3-D Cartesian mesh inside room was generated by GAMBIT with a uniform grid spacing of 3" In the following sections,...

Ngày tải lên: 05/09/2013, 16:11