data and workflow management for large scale biological reseearch

... Python library for large-scale analysis of computational protein design data and structural bioinformatics Jaume Bonet1,2, Zander Harteveld1,2, Fabian Sesterhenn1,2, Andreas Scheck1,2and Bruno E ... library for the analysis of large-scale structural data tailored for CPD applications rstoolbox is oriented towards both CPD software users and developers, being easily integrated in analysis workflows ... func-tions for multiple data types, including computational de-sign simulations and experimental data, in a variety of formats; II) rstoolbox.analysis - provides functions for sequence and structural

Ngày tải lên: 25/11/2020, 12:15

... applications in Scala for processing and analyzing large-scale data • Interactively analyze large-scale data with Spark SQL using just SQL and HiveQL • Process high-velocity stream data with Spark ... designed for batch data processing It has high throughput and high latency It is great for data transformation or ETL (extract, transform, and load) jobs, but not an ideal platform for interactive ... between text and binary formats is significant Therefore, binary formats are generally preferred for storing large datasets This section describes some of the commonly used binary formats for serializing

Ngày tải lên: 04/03/2019, 13:44

... which allows for large-scale spatial multiplexing and highly directional beamforming This leads to the advent of large-scale or massive multiple-input multiple-output (MIMO) con-cept for mmWave ... solution, the mutual information between the data symbols and the processed signals before digital combiner is approximately equal to the mutual information between the data symbols and the final processed ... between the BS and each user terminal assuming uniformly random angles of arrival and departure and ˜d = λ 2 For each simulation, the average spectral efficiency channel realizations A Performance

Ngày tải lên: 26/03/2020, 03:44

... concentration in forensic and biomedical investigations Fig 5 Superimposed HPLC–DAD chromatograms obtained for: a spiked and unspiked samples extracted with SALLE, and pure stand‑ ards (60, 60, and 30 ... (GC-FID) [10] and high per-formance liquid chromatography (HPLC) [11–15] have been reported for analyzing khat samples within pharma-cological, phytochemical, forensic and law enforcement applications ... obtained for the three analytes in the con-centration range of 1.5–240, 1.5–240 and 0.75–120  µg/ mL for norephedrine, cathine, and cathinone, respec-tively The slope and intercept values for calibration

Ngày tải lên: 29/05/2020, 12:38

... clicks and subsequently test their new OncoTrack data management work package DB [8] as central repositories for clinical and biological data, respectively Here, we describe the collaborative effort ... different data levels and data types into separate study-trees to better organise the different categories (clinical data and lab data) Under the Clinical Data tree, general subject information ... are stored The Lab Data stores data generated in the lab (e.g Treatment Data, OMICS Data) In each subtree under the “Treatment Data” and the “OMICS Data”, the subject/ sample information as well

Ngày tải lên: 25/11/2020, 12:08

... challenge for broader data interpret-ation and further explorinterpret-ation of large-scale combininterpret-ation datasets We thus aimed to develop a methodology to improve synergy calling and assign ... pairs In this dataset, synergism was initially deter-mined from a single combination data point (i.e a single well) and two singlets (single drug wells) This large data-set did allow for the identification ... AccessStatistical assessment and visualization of synergies for large-scale sparse drug combination datasets Arnaud Amzallag1,2,3,6* , Sridhar Ramaswamy1,2,3,4,5and Cyril H Benes1,2* Abstract

Ngày tải lên: 25/11/2020, 13:22

... applications in Scala for processing and analyzing large-scale data • Interactively analyze large-scale data with Spark SQL using just SQL and HiveQL • Process high-velocity stream data with Spark ... designed for batch data processing It has high throughput and high latency It is great for data transformation or ETL (extract, transform, and load) jobs, but not an ideal platform for interactive ... between text and binary formats is significant Therefore, binary formats are generally preferred for storing large datasets This section describes some of the commonly used binary formats for serializing

Ngày tải lên: 19/01/2021, 11:11

... technological, organizational, and environmental factors The findings revealed notable differences in big data adoption based on firm type and highlighted data privacy and organizational data environment as ... entails (data optimization) It highlights the cyclical relationship between information management and its impact on individuals, teams, and enterprises Through various perspectives and case ... chapter authors for their time and expertise, acknowledges the reviewers for enhancing the quality and coherence of the chapters, and appreciates the editorial advisory board members for their unique

Ngày tải lên: 07/12/2021, 14:45

... unconstrained large scale global optimization problems with size up to 1000 dimen-sions in order to investigate the general performance of the proposed algorithm for solving large scale global ... bond stretching force constant, c2 ijis the angle bending force constant, and c3 ij is the torsion force constant The constants r0 ij andh0 ij represent the preferred bond length and bond angle, ... against the standard particle swarm optimization to solve large scale global optimization problems and 9 benchmark algorithms, in order to verify the efficiency of the proposed algorithm for solving

Ngày tải lên: 08/11/2022, 14:57

... structure and works well for both linear and non-linear associations In addition, it works well for both cate-gorical and continuous data without making assumptions about the data type Random forest ... article, we investigated the performance of a forest-based feature screening approach for detecting epistatic, correlative, and polygenic effects for large-scale genome data Besides the difficulties ... of contemporary genome data Keywords: Feature screening, GWAS, Epistasis, Random forest, Large-scale modeling Background High-throughput genotyping techniques and large data repository capability

Ngày tải lên: 27/03/2023, 05:18

... applications in Scala for processing and analyzing large-scale data • Interactively analyze large-scale data with Spark SQL using just SQL and HiveQL • Process high-velocity stream data with Spark ... designed for batch data processing It has high throughput and high latency It is great for data transformation or ETL (extract, transform, and load) jobs, but not an ideal platform for interactive ... between text and binary formats is significant Therefore, binary formats are generally preferred for storing large datasets This section describes some of the commonly used binary formats for serializing

Ngày tải lên: 17/04/2017, 15:20

... Trang 1 Integrated soil and water management for orchard development Role and importance Trang 3Integrated soil and water management for orchard development Role and importance Proceedings ... soll and water management for vineyard and Ltdeatanacala Importance of olive-ll production in italy 8 —— Therole and importance of integrated sil and water management -2 Betee Mũ Phante and Sagha? ... International Seminar “The role and importance of integrated soil and ‘water management for orchard development” organized by the FAO Land and Water Development Division and the College of Agricultural

Ngày tải lên: 17/03/2014, 16:20

... channel, and later create synthetic data with the same properties for evaluating link and system-level perfor-mance, and so on Large-scale parameters are based on this concept The term large-scale ... different large-scale parameters at the same site are calculated for the two separate measurement campaigns In Tables5and6, the cor-relation coefficients for the two base stations, sectors A and B, ... between sec-tors B and C of 2004 are similar as between secsec-tors 1 and 2 of 2005 In both cases, the two BSs are on the same roof, and separated 20 and 50 meters for 2004 and 2005, respectively

Ngày tải lên: 22/06/2014, 06:20

... 0.01s-1 and kr = 0.001s-1 for E_AB, E_BC, and E_FG; kf = 0.1s-1 and kr = 0.098s-1 for E_CD and E_DF; kf = 0.1s-1 and kr = 0.097s-1 for E_CE and E_EF; and kf = 0.1s-1 and kr = 0.96s-1 for E_CF ... 0.091s-1 for E_DF and E_EG, and kf = 0.01s-1 and kr = 0.001-1 for the other reac-tions in the pathway of Figure 2a The initial metabolite concentrations were 1.0 mM for A, B and C, and 0.5 mM for ... distribution was employed for the ideal reaction rate distribution in the static module; the ideal reaction rates were 2 µM/s for E_CD and E_DF, 3 µM/s for E_CE and E_EF, and 4 µM/s for E_CF All the initial

Ngày tải lên: 13/08/2014, 23:20

... protein-protein interactions in preparation for large-scale mapping of the human interactome Addresses: * Center for Systems and Synthetic Biology and Institute for Cellular and Molecular Biology, University ... retrieving these data manually is made difficult by the large number of articles, all lacking formal structure Automated extraction of information would be preferable, and therefore, mining data from ... interactions and to establish measures of accuracy that are useful for the evaluation and integration of upcoming data-sets We established two benchmarks for assessing the quality of large-scale human

Ngày tải lên: 14/08/2014, 14:21

... there is information asymmetry between management and investors (Leland and Pyle, 1977), and between informed and uninformed investors (e.g Rock, 1986; Beatty and Ritter, 1986), and such information ... 5characterized by information asymmetry between management and investors (Leland and Pyle, 1977), and between informed and uninformed investors (Rock, 1986; Beatty and Ritter, 1986) Several analytical models ... management increases with the level of information asymmetry For example, Dye (1988) and Trueman and Titman (1988) demonstrate that the existence of information asymmetry between management and

Ngày tải lên: 06/01/2015, 19:41

... and operational data logging and processing, on-platform information distribution and displaying, infrastructure monitoring/intrusion detection, and management of complex surface facilities and ... applications need large amounts of data transfers The time consumed in data transfers may form the large portion of the application completion time Therefore, computational tasks and data transfer ... high demand for computational and data resources Large scale scientific applications are the main drivers for this demand since they involve large number of simulations and these simulations generate...

Ngày tải lên: 30/10/2014, 20:07

... information, the data management system should be able to handle different data types and data representation formats Also, as the query requirements can differ according to the data type, the ... following classes of data storage servers are identified – location data, static spatial data, indoor spatial data, embedded system data, data from a smart home and dynamic sensor data The last class ... repository database queries Distributed set of context data Querying the repository using repositories Historical data database queries Dynamic data management Not applicable Not handled Not handled...

Ngày tải lên: 30/09/2015, 05:44

... node), and so forth Results are shown for the three different protocols for initializing a new node’s state, with (“Estimation”) and without (“Standard”) the heuristic mentioned in Section 2.5, and ... [11, 21] and SCRIBE [22], and several applications are under development 2.4 Self-organization and adaptation In this section, we describe Pastry’s protocols for handling the arrival and departure ... peer-to-peer applications and understanding more of the issues and requirements of such applications and systems [1, 2, 5, 8, 10, 15] One of the key problems in large- scale peer-to-peer applications...

Ngày tải lên: 28/04/2014, 13:40

... stochastic gradient method for updating the beamformers 4.1 Stochastic gradient algorithm for beamformer update The algorithm for the beamformer update is a generalization of [14] and is described as ... best transmit and receive beamformers from the previous iteration and generates Kt -1 new transmitand K r -1 new receive beamformers for the current iteration With a fixed step size and a single ... which a largescale MIMO system with Nt = 32 and Nr = 10 transmit and receive antennas operating at the 60 GHz band is randomly located All the antennas are omni-directional with 20 dBi gain and vertical...

Ngày tải lên: 21/06/2014, 01:20