concepts in action part 2
TECHnoLogY in ACTion™Learn Electronics with Arduino Learn eLectronics concepts whiLe buiLding pptx
... try using the 2N 222 2A component It can handle currents as high as 50 mA 21 CHAPTER ■ Electronic Singing Bird Figure 1 -29 The final prototype of the electronic singing bird Creating the Interactive ... const int buttonPin = 2; int lightpins[3] = {8,11,13};//Change sequence of LEDs Here! int state=0; void setup() { pinMode (buttonPin,INPUT); pinMode (lightpins[0],OUTPUT); pinMode (lightpins[1],OUTPUT); ... following line of instruction: int blinktime = 20 ; delay(blinktime); By changing the integer value of the variable blinktime, the delay instruction will provide the appropriate switching pulsing...
Ngày tải lên: 05/03/2014, 17:20
Insulin Action and Its Disturbances in Disease - part 1 ppsx
... References 20 7 20 7 20 9 21 0 21 0 21 1 21 1 21 2 21 2 21 3 21 4 21 4 21 5 21 6 21 7 21 7 21 8 21 8 21 9 22 0 22 0 22 2 22 4 22 4 22 4 PPARγ and Glucose Homeostasis Robert K Semple and Stephen O’Rahilly 23 7 9.1 9 .2 Evidence ... SH3 PtdIns (PI3K) Bcr (PI3K) PtdIns 4-K SH2 p85 binding p110 binding PtdIns-4-P p110 (catalytic) PtdIns 4-K PtdIns-3-P Ras binding SH2 PtdIns 5-K PTEN PtdIns(3,4)P2 Phospholipase C PTEN PtdIns(3,4,5)P3 ... leading to insulin resistance Candidate genes involved in the mechanisms of insulin resistance Insulin signalling network Factors leading to insulin resistance Defining the function of the insulin...
Ngày tải lên: 09/08/2014, 15:20
Insulin Action and Its Disturbances in Disease - part 3 pptx
... 11, 12 13 14 15 57 16 18, 17 18, 19 20 20 21 58, 59 60 24 61 25 22 62 26 27 28 30 Bat IRKO Muscle GLUT4 KO Normal insulin sensitivity Obesity, dyslipidaemia Lean, insulin sensitive Insulin resistance, ... (−/−) SREBP1c LPL Increased insulin sensitivity Increased insulin sensitivity Increased insulin resistance Obesity/maintained insulin sensitivity Lethal Lean/increased insulin sensitivity Lethal ... transduction pathways involved in the regulation of protein synthesis by insulin in L6 myoblasts Am J Physiol 27 4, C 221 –C 228 Southorn, B G and Palmer, R M (1990) Inhibitors of phospholipase A2 block the...
Ngày tải lên: 09/08/2014, 15:20
Insulin Action and Its Disturbances in Disease - part 4 pdf
... 0-470-85008-6 20 8 RELATIONSHIP BETWEEN FAT DISTRIBUTION AND INSULIN RESISTANCE Increased risk of diabetes 100 93 .2 80 60 54.0 40.3 40 27 .6 20 15.8 1.0 2. 9 4.3 5.0
Ngày tải lên: 09/08/2014, 15:20
Insulin Action and Its Disturbances in Disease - part 5 pptx
... factors, including endocrine factors secreted from the adipocyte, such as TNFα, adiponectin and leptin .27 , 28 Figure 10 .2 Transcription factors regulating adipogenesis 27 2 ADIPOKINES AND INSULIN RESISTANCE ... IMPLICATED IN INSULIN RESISTANCE 27 3 In the healthy individual insulin is a potent stimulator of glucose uptake in the adipocyte, muscle and liver Insulin binds to its receptor, the insulin receptor ... on insulin signalling Resistin At the turn of the 21 st century a novel cysteine rich adipokine was discovered that was claimed to be the link between obesity and insulin resistance .20 2, 20 3 In...
Ngày tải lên: 09/08/2014, 15:20
Insulin Action and Its Disturbances in Disease - part 6 pps
... plasma insulin measured on a sub-set of 695 individuals Fasting and h insulin Fasting serum insulin (Fasting insulin resistance index: ‘a multiplication value of fasting insulin and fasting glucose ... Caucasians Participant characteristics OGTT–fasting and post-challenge insulin Fasting insulin OGTT–fasting and post-challenge insulin Measure of insulin resistance Table 12. 1 (continued ) Age, fasting ... ( 12. 1) years BMI: 25 .5 (4 .2) Ethnicity: Hispanics and Non-Hispanic Caucasians Fasting insulin Fasting insulin IVGTT Fasting insulin Age, BMI, SES, smoking, heavy drinking, existing CHD Three-way analysis...
Ngày tải lên: 09/08/2014, 15:20
Insulin Action and Its Disturbances in Disease - part 8 pdf
... 97, 12 222 – 12 226 68 Hawkins, M., Barzilai, N., Liu, R., Hu, M., Chen, W and Rossetti, L (1997) Role of the glucosamine pathway in fat-induced insulin resistance J Clin Invest 99, 21 73 21 82 69 ... and Tataranni, P A (20 02) REFERENCES 118 119 120 121 122 123 124 125 126 127 128 435 Plasma adiponectin concentration is associated with skeletal muscle insulin receptor tyrosine phosphorylation, ... linkages for metabolic syndrome phenotypes Locus or gene 2p21 (D2S1788) 3q27 17p 12 APO E CEPT 16p13–pter 3q27 8q23 6q 22 q23 ∗ Phenotype(s) Leptin levels, fat mass Several indicators Several indicators...
Ngày tải lên: 09/08/2014, 15:20
Insulin Action and Its Disturbances in Disease - part 9 pot
... of phosphoinositide 3-kinase by insulin in fibroblasts from patients with severe insulin resistance and pseudoacromegaly REFERENCES 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 529 A disorder ... factor-alpha causes insulin receptor substrate -2- mediated insulin resistance and inhibits insulin-induced adipogenesis in fetal brown adipocytes Endocrinology 139, 122 9– 123 8 56 Feinstein, R., Kanety, ... (FIRI),41 fasting glucose insulin ratio ,24 and quantitative insulin sensitivity check index (QUICKI) 42 and others Determining the fasting glucose insulin ratio could be a good screening test in that...
Ngày tải lên: 09/08/2014, 15:20
Insulin Action and Its Disturbances in Disease - part 10 ppt
... depots 21 5 adipocytokines 24 5–8, 476 adipogenesis 27 1 adipokines 66, 26 9–70, 26 9, 28 0 insulin resistance 27 2 adiponectin 27 9–80 interleukin-6 (IL-6) 27 4–6 leptin 27 6–8 resistin 27 8–9 tumour necrosis ... pattern 20 8, 20 9, 22 2 change in adipocyte phenotype with obesity 21 0 gynoid pattern 20 8, 20 9, 22 2 mechanisms linking central obesity to metabolic syndrome 21 2 adipose tissue as an endocrine organ 21 4–15, ... PPARγ 23 7–8 cell and rodent models 23 8 adipocytokines 24 5–8 adipose tissue insulin sensitivity 24 2 dietary lipid handling 24 2–5, 24 4 liver 24 9–51, 25 1 pancreatic β-cells 24 9, 25 1 skeletal muscle 24 8–9,...
Ngày tải lên: 09/08/2014, 15:20
Insulin Action and Its Disturbances in Disease - part 2 pptx
... Relative involvement of Shc tyrosine residues 23 9 /24 0 and tyrosine 317 on insulin-induced mitogenic signaling 52 2 12 213 21 4 21 5 21 6 21 7 21 8 21 9 22 0 22 1 22 2 22 3 22 4 22 5 22 6 THE INSULIN RECEPTOR ... 54 24 3 24 4 24 5 24 6 24 7 24 8 24 9 25 0 25 1 25 2 25 3 25 4 25 5 25 6 25 7 THE INSULIN RECEPTOR AND DOWNSTREAM SIGNALLING platelet-derived growth factor BB-, insulin-like growth factor I- and insulin-mediated ... 197 198 199 20 0 20 1 20 2 20 3 20 4 20 5 20 6 20 7 20 8 20 9 21 0 21 1 51 Possible mechanism for suppression of insulin-stimulated tyrosine phosphorylation of IRS-1 J Biol Chem 27 0, 23 780 23 784 Hotamisligil,...
Ngày tải lên: 09/08/2014, 15:20