... owing to its cost and rarity The future of radium mining in the United States for use in medical ments was pushed forward by the incorporation of the National Radium Institute in 1913, a joint ... damages arising herefrom. Library of Congress Cataloging-in-Publication Data Radiation oncology in palliative cancer care / edited by Stephen Lutz, Edward Chow, Peter Hoskin. p ; cm. Includes ... radiotherapy in advanced lung cancer, 163 George Rodrigues, Benjamin Movsas Introduction, 163 Radiotherapy treatment, 165 Trang 1115 Palliative radiotherapy for gastrointestinal and colorectal cancer,
Ngày tải lên: 21/01/2020, 18:16
... (Accurray) show interesting results in a number of situations including locally advanced carcinoma of the pancreas Special considerations in developing countries Patients in developing countries ... management of the other rare cancers should be based on first principles in the absence of substantive evidence to support a standard of care Renal cancer is increasing in incidence in the western world ... tumor types will be discussed, including denosumab and radium-223 Renal cancer The recent increases in kidney cancer incidence are predominantly because of increasing numbers of cases with stage
Ngày tải lên: 22/01/2020, 00:06
Dual role of CD44 isoforms in ampullary adenocarcinoma: CD44s predicts poor prognosis in early cancer and CD44ν is an indicator for recurrence in advanced cancer
... isoforms in ampullary adenocarcinoma: CD44s predicts poor indicator for recurrence in advanced cancer Cheng-Lin Wu1†, Ying-Jui Chao2,3†, Ta-Ming Yang4, Yi-Ling Chen5, Kung-Chao Chang1, Hui-Ping Hsu2*, ... stimulates the proliferation and invasion of cancer cells; however, its interaction with ezrin/radixin/moesin proteins activates the tumor suppressor, merlin, to inhibit cancer growth [16] Differ-ent ... of CD44s in prostate cancer and increased expression of CD44ν7-10 induced invasion, migration and independent growth of cancer cells [25] In addition, the cytoplasmic domain of CD44 interacts
Ngày tải lên: 22/09/2020, 22:49
‘Burden to others’ as a public concern in advanced cancer: A comparative survey in seven European countries
... concerning)* 1 Having no energy 2 Being in pain 3 Changes in the way you look 4 Having no appetite at all 5 Being a burden to others 6 Being unable to get your breath 7 Being alone 8 Feeling as if you ... living alone varying from 24% in England to 11% in Italy and Portugal 64% described themselves as being religious or belonging to a denomination, ranging from 46% in the Netherlands to 82% in ... Cherlin E, Bradley EH: What is a good death? Minority and non-minority perspectives J Palliat Care 2003, 19(3):168 –175. 6 Higginson IJ, Costantini M: Dying with cancer, living well with advanced
Ngày tải lên: 05/11/2020, 07:19
Malnutrition screening and assessment in the cancer care ambulatory setting
... patients attending an ambulatory cancer care setting [18] Interestingly, to standardize the clinical practice of malnutrition diagnosis in clinical settings, the Global Leadership Initiative on ... malnutrition [36] In cancer patients, muscle wasting is particularly frequent and is associated with increased morbidity and mortality [37] In fact, in a study in patients with advanced-stage cancer, 6-month ... Cross-sectional observational study including 246 adult ambulatory patients with cancer receiving in-chair intravenous treatment at a cancer care centre in Australia Anthropometrics, handgrip strength
Ngày tải lên: 27/11/2021, 17:16
Values and options in cancer care (VOICE): Study design and rationale for a patient-centered communication and decision-making intervention for physicians, patients with advanced
... insufficient progress in improving clinical communication in the context of serious illness The 2007 NCI monograph, Patient-centered Communication and Cancer Care [1], the Institute of Medicine ... patients with advanced cancer, and caregivers to communicate more effectively about issues likely to influence decision making In doing so, this investigation brings together research on communication ... essential for informed decision making in advanced cancer Our intervention is designed to promote patient-centeredness [20], which is defined by the Institute of Medicine [21] as“care that is
Ngày tải lên: 05/11/2020, 06:14
The feasibility and benefit of a brief psychosocial intervention in addition to early palliative care in patients with advanced cancer to reduce depressive symptoms: A pilot randomized
... (according to the clinical oncologist’s opinion); (6) exhibiting one of the following metastatic or recurrent incurable cancers: breast cancer, platinum-resistant ovarian cancer, cervical cancer, ... Discussing the Evidence for Upstream Palliative Care in Improving Outcomes in Advanced Cancer. Am Soc Clin Oncol Educ B [Internet] 2016 [cited 2016 Nov 29];36:e534 –8. 2 Smith TJ, Temin S, Alesi ... CBT approach in cancer patients, including improvement in the state of health, changes in behavior, reduction in sig-nificant symptoms and depression, and greater inde-pendence in symptom management
Ngày tải lên: 06/08/2020, 05:03
Some fundamental issues in receiver design and performance analysis for wireless communication
... performance analysis in wireless communication andour detailed research objectives in this area in Section 1.2 In Section 1.3, we give a summary of our main contributions in the two areas Finally, we present ... gain monitoring that has higherreliability in time-varying channel than conventional ARQ schemes Finally, the concluding remarks are drawn in Chapter 8 and possible extensions of the work in ... gain h Due to the independence of{h i } N i=1, this is equivalent to minimizing each term with respect to h i individually Using the orthogonal projection theorem, the quantity in (2.7) is minimized
Ngày tải lên: 10/09/2015, 15:51
Topical issues in anesthesia and intensive care
... antibiotic- dosing adjustments in CRRT involve estimating ongoing extracor-poreal clearance (e.g., 15 mL/min) and dosing the antibiotic according to the guidelines for the equivalent creatinine clearance ... (1999) Pharmacodynamics of intermittent and continuous infusion cefepime alone and in combination with once daily tobramycin against Pseudomonas aeruginosa in an in vitro infection model Chemotherapy ... and in plasma Sc Drug concentration in filtrate Drug concentration in plasma = In general, the sieving coefficient has a range that goes from 0 to 1 Drug binding to proteins is the main determinant
Ngày tải lên: 14/05/2018, 15:13
Oncologists’ perception of depressive symptoms in patients with advanced cancer: Accuracy and relational correlates
... the findings clearly emphasize the role of relational skills in detecting these symptoms They dem-onstrate the value of using structured screening instru-ments and of training physicians in relational ... National Cancer Institute (SHS SPE 2010) and supported by the CHU Sainte-Justine Foundation, the Larry and Cookie Rossy Foundation, and Industrial Alliance These finding bodies did not participate in ... examin-ing individual symptoms Previous studies have not offered this level of analysis, and have often presented inappropri-ate statistical indices Finally, this study adds to the exist-ing
Ngày tải lên: 10/01/2020, 13:19
Lecture Managerial finance - Chapter 28: Advanced issues in cash management and inventory control
... Trang 1 1Chapter 28 Advanced Issues in Cash Management and Inventory Control Trang 3 3Why is inventory management vital to the financial health of most firms? Insufficient inventories can lead to lost sales ... Inventory management is more closely related to operations than to finance Trang 4 4Total Inventory Costs (TIC) TIC = Total carrying costs+ total ordering costs Trang 6 6TIC Carrying Cost Ordering Cost 0 EOQ Units $ Average inventory = EOQ/2. Inventory Model Graph ... decrease, but ordering costs increase. If Q > EOQ, total carrying costs increase, but ordering costs decrease. Trang 12 12Suppose delivery takes 2 weeks. Assuming certainty in delivery and usage, at what
Ngày tải lên: 16/01/2020, 19:29
Parkin gene mutations are not common, but its epigenetic inactivation is a frequent event and predicts poor survival in advanced breast cancer patients
... theParkin protein expression where we also found a lower level ofParkin pro-tein in cancer tissues in contrast to normal tissues (Fig.3 & d) Oncomine study demonstrated that expression of Parkin ... colon cancer, glioblast-oma, in addition to lung cancer [5] Remarkably,Parkin mutations sometimes occur in the same domains or even at the same amino acids in cancer, which, when found in germline, ... of Parkin may promote cancer however the precise mechanism ofParkin inactiva-tion remains unexplored mainly in breast cancer Aberrant promoter methylation is a widespread mech-anism in cancer
Ngày tải lên: 17/06/2020, 17:24
Fostering efficacy of anti-PD-1-treatment: Nivolumab plus radiotherapy in advanced non-small cell lung cancer - study protocol of the FORCE trial
... performing any protocol-related procedures, including screening evaluations. • Subject is willing and able to coxmply with the protocol for the duration of the study including undergoing treatment ... uncontrolled medical disorder, active infection, physical examining, laboratory finding, altered mental status, or psychiatric condition that, in the opinion of the investigator, would limit a subject ... no individual patient data are contained in this manuscript. Competing interests The FORCE trial received funding from Bristol-Myers Squibb GmbH & Co.K-GaA (BMS) BMS has not been involved in
Ngày tải lên: 17/06/2020, 18:37
Quality indicators of clinical cancer care for prostate cancer: A population-based study in southern Switzerland
... the definition of thresholds of minimal standard of care. Keywords: Quality of cancer care, Prostate cancer, Quality indicators, Cancer registry, Population-based study Background Prostate cancer ... L E Open AccessQuality indicators of clinical cancer care for prostate cancer: a population-based study in southern Switzerland Abstract Background: Quality of cancer care (QoCC) has become an ... frequent cancer in men. In 2012, it represented almost 22% of all new cancer diagnoses in Europe and, despite the good prognosis, it is the second leading cause of death due to cancer [ 1 ] In Switzerland,
Ngày tải lên: 03/07/2020, 00:58
The PREgnancy and FERtility (PREFER) study: An Italian multicenter prospective cohort study on fertility preservation and pregnancy issues in young breast cancer patients
... far to investigate all the issues related to safety and monitoring of pregnancy in cancer survivors Pregnancy-associated breast cancer (PABC) is defined as breast cancer diagnosed during pregnancy ... barriers remain in discuss-ing and dealdiscuss-ing with these issues The PREFER study represents a comprehensive program in young breast cancer patients across several Italian institutions aiming to ... evidence suggesting that the incidence of breast cancer in young women and the occurrence of PABC are increasing [21, 22] More-over, in western countries, there is a current trend of postponing pregnancy
Ngày tải lên: 06/08/2020, 07:09
Surfactant protein-D predicts prognosis of interstitial lung disease induced by anticancer agents in advanced lung cancer: A case control study
... examina-tions, including HRCT findings, pulmonary function test, BAL fluid analysis, and pathological findings [11] It is important to distinguish between ILD-AA and other types of ILD, including ... between change in serum markers and pre-existing IPF (data not shown) Moreover, there were no findings of carcinomatous lymphangitis, including the thickening of the bronchovascular bundle, inter-lobular ... pre-existing interstitial shadow Moreover, pre-existing interstitial shadow in all patients were categorized into IIPs Of these patients, 14 patients with pre-existing interstitial shadow were clinically
Ngày tải lên: 06/08/2020, 07:49
Supporting the patients with advanced cancer and their family caregivers: What are their palliative care needs
... Previous experience in providing care for someone sick a “Partially” referring to less than 50% involvement in caregiving role b “Yes” referring to at least 50% involvement in the caregiving role Trang ... pa-tient, caregiving roles, assistance with caregiving, caregiver’s medical condition, clinical setting, and whether patients were receiving palliative care Functional status of the patients cared ... prob-lems (including caregivers’ training needs as part of quality care for patients) and provide timely information and supportive care In addition, our results highlight the importance of ensuring
Ngày tải lên: 19/09/2020, 22:08
Implementing exercise in cancer care: study protocol to evaluate a communitybased exercise program for people with cancer
... identified the importance of incorporating exercise in comprehensive cancer care but information regarding effective approaches to translating evidence into practice is lacking This paper describes ... of increased primary health care use in cancer survivors J Clin Oncol 2012; 30(33):4155 –60. 8 Ganz PA, Earle CC, Goodwin PJ Update on Progress in Cancer Survivorship Care and Research J Clin ... comprehensive cancer care [26], translation strategies for the integration of efficacious exercise programs into routine cancer care are limited There is a clear paucity of research investigating the design
Ngày tải lên: 20/09/2020, 01:20
Phase-specific and lifetime costs of cancer care in Ontario, Canada
... esophageal cancer in the initial phase, and lymphoma, colorectal and thyroid cancers in the continuing phase, indicating similarity in costs There Table 1 Characteristics of patients diagnosed with cancer ... which includes same-day surgeries/procedures and emergency department visits), Continuing Care Reporting System (other institution-based care), Ontario Home Care Administrative System and Home Care ... Fig 1 Cancer care continuum in Ontario Source: Ontario Cancer Plan IV 2015-2019, Cancer Care Ontario https://cancercare.on.ca/common/ pages/UserFile.aspx?fileId=333871 Trang 4to the terminal phase;
Ngày tải lên: 20/09/2020, 18:18
FERTILITY ISSUES IN CHILDHOOD CANCER TREATMENT pptx
... females Cisplatin Carboplatin Doxorubicin Specific Regimens: VAMP w/COP Low Risk/No Risk: Cytarabine Vincristine Methotrexate Dactinomycin Bleomycin Mercaptopurine Vinblastine Page Risk of infertility ... years away from having children of his or her own, thinking about his or her fertility before starting cancer treatment can help increase the chances of being able to have children in the future Talk ... of taking hormone therapy with their doctor Low levels of ovarian hormones also increase the risk of bone thinning (osteoporosis) Getting enough calcium and vitamin D (in the diet or by taking...
Ngày tải lên: 15/03/2014, 01:20