... still could not account for the very high clinical CL/Foral values Therefore, the rate of metabolism in intestinal microsomes was investigated Reaction phenotyping, in recombinant expressed human ... accounting for species differences in intestinal metabo-lism when making projections of human Foral and dose for CDs based on in vitro and pre-clinical PK data typically available during the drug ... cost of bringing a drug to market, that the accuracy and certainty of these predictions face considerable scrutiny The purpose of this article is to discuss the importance of understanding and
Ngày tải lên: 11/05/2020, 11:45
... the need for unification of the international law of the contract of sale of goods within the framework of international CISG volume due to the growing trade between the member countries of the ... at the time of delivery, at the place of delivery.52 One other thing to note is in the process of drafting the Convention as well as the body of the Convention, the composer always uphold the international ... presentations, the thesis will give the inestimable experiences for Vietnam in the future in case Vietnam signs to be the official Contracting States to the Convention 3 Delimitation of the Thesis With the
Ngày tải lên: 20/04/2021, 22:52
The application of cisg in united states experience for vietnam
... the need for unification of the international law of the contract of sale of goods within the framework of international CISG volume due to the growing trade between the member countries of the ... at the time of delivery, at the place of delivery.52 One other thing to note is in the process of drafting the Convention as well as the body of the Convention, the composer always uphold the international ... presentations, the thesis will give the inestimable experiences for Vietnam in the future in case Vietnam signs to be the official Contracting States to the Convention 3 Delimitation of the Thesis With the
Ngày tải lên: 21/04/2021, 20:03
Application of the standard method for the determination of acrylamide in heat-processed starchy foods by GC
... value for the x-axis obtained from the calibration curve, when the value of the y-axis was equal to zero, was calculated as the amount of the analyte in unspiked portion of the sample In 1993, ... that the major brominated derivative of acrylamide detected in DB-17 capillary column was in fact 2-BPA, suggesting that the dehydrobomination had occurred either in the injection port of the ... Supelco Inc., PA, USA) Separations were performed using nitrogen as the carrier gas Following injection, the column was held at 60°C for 1 min, then programmed at 20 °C/ min to 220°C and held for
Ngày tải lên: 12/09/2021, 13:01
THE APPLICATION OF CISG IN UNITED STATES EXPERIENCE FOR VIET NAM (luận văn thạc sỹ luật)
... the need for unification of the international law of the contract of sale of goods within the framework of international CISG volume due to the growing trade between the member countries of the ... at the time of delivery, at the place of delivery.52 One other thing to note is in the process of drafting the Convention as well as the body of the Convention, the composer always uphold the international ... presentations, the thesis will give the inestimable experiences for Vietnam in the future in case Vietnam signs to be the official Contracting States to the Convention 3 Delimitation of the Thesis With the
Ngày tải lên: 15/01/2022, 22:32
The application of cisg in united states experience for vietnam
... the need for unification of the international law of the contract of sale of goods within the framework of international CISG volume due to the growing trade between the member countries of the ... at the time of delivery, at the place of delivery.52 One other thing to note is in the process of drafting the Convention as well as the body of the Convention, the composer always uphold the international ... presentations, the thesis will give the inestimable experiences for Vietnam in the future in case Vietnam signs to be the official Contracting States to the Convention 3 Delimitation of the Thesis With the
Ngày tải lên: 14/08/2023, 06:37
Báo cáo lâm nghiệp: "of morphological characters and molecular markers for the analysis of hybridization in sessile and pedunculate oak" pps
... 1995) During autumn 1989, seeds were col-lected in the crown of several open-pollinated trees of the two species A map of the positions of the mother trees in the stand is given in figure 1. The ... genotype n/n (P In the second case of the figure, the het-erozygote deficit (f) must be considered The fre-quency of the phenotype A+ is the sum of the frequency of the genotype P and of the genotype ... between the means of the groups was significant in sig-nificant in sessile oak were the same over the three analyses the family 97 remained classified in the space of the other species over the
Ngày tải lên: 08/08/2014, 18:21
Báo cáo y học: "Clinical guidelines for the recognition of melanoma of the foot and nail unit." doc
... compared to other forms of skin cancer, the disease is relatively uncommon [6] However in the UK, like much of the world, the incidence of cutaneous melanoma continues to rise accounting for the majority ... tumour (cancer) arising from the pigment producing cell of the skin, the mela-nocyte The number of cases of malignant melanoma worldwide is increasing faster than any other form of cancer amongst ... melanoma on the skin of the foot. Trang 4suggests many cases of melanoma are brought to theattention of the patient by co-incidental trauma and injury The role of trauma in the aetiology of melanoma
Ngày tải lên: 10/08/2014, 21:24
Báo cáo khoa học: " Comparisons of Sampling Procedures and Time of Sampling for the Detection of Salmonella in Danish Infected Chicken Flocks Raised in Floor Systems" pptx
... test the null hypothesis of marginal symmetry, namely that the probability of an observation being classi-fied into cell [i,j] in the contingency table is the same as the probability of being ... effective in detecting S enterica as the 60 faecal samples In broiler flocks, 5 pairs of socks were used both in the routine samples taken at about 3 weeks of age for the establishment of infection of ... identification of infected flocks to be included in the study, and in the follow-up samples, typ-ically taken a few days before slaughtering the animals This provided an opportunity for studying infection
Ngày tải lên: 12/08/2014, 15:20
Báo cáo khoa học: "Recombinant activated factor VIIa for the treatment of bleeding in major abdominal surgery including vascular and urological" doc
... design of the work, sam-pling of data, interpretation of the data, and drafting of the arti-cle JK contributed to the conception of the work, interpretation of the data, revision of the article for ... con-traindication for the administration of rFVIIa [35] Since there are no controlled studies on bleeding therapy in abdominal surgery, the formal degree of evidence on the use of rFVIIa in patients ... series included in the meta-analysis, there is no information on the dose in the subgroup of patients with interventions in the abdominal region [11,13] In the other 30 patients, the initial rFVIIa
Ngày tải lên: 13/08/2014, 10:20
Báo cáo y học: "Could increased axial wall stress be responsible for the development of atheroma in the proximal segment of myocardial bridges?" pot
... is the force generated by the drag of the blood in the tun-neled segment; F3 is due to the pressure pushing in upstream direction in the exit cone of the bridge, and F tis-sue is the retaining ... x = 0 in Fig 3) Since the ves-sel is more or less tethered to the surrounding tissues, the local wall elongations induced by this force generate in turn retaining forces in these tissues The resulting ... retaining axial force provided by the myocardial tissues surrounding the artery distally of the cross section x = 0 In the following, we mainly consider the effect of these four forces in the wall cross
Ngày tải lên: 13/08/2014, 16:21
Báo cáo y học: " A multi-center, randomized, double-blind, parallel, placebo-controlled trial to evaluate the efficacy, safety, and pharmacokinetics of intravenous ibuprofen for the treatment of fever in critically ill and non-critically ill adults" pdf
... and for the reduction of fever in adults and in children [1] Ibuprofen was first developed as an anti-rheumatic drug in the 1960 s [2] Ibuprofen is believed to work by inhibiting the formation of ... was administered in a 100 mL bag of normal saline Addi-tion of IV ibuprofen to the bag for diluAddi-tion did not notice-ably affect the volume of the infusion bag, since only a maximum of 4 mL ... secondary endpoints, 21 of 30 (70%) of subjects in the 200 mg IV ibuprofen group, and 19 of 31 (61%) of subjects in the 100 mg IV ibuprofen group, compared to 9 of 28 (32%) of the placebo group
Ngày tải lên: 13/08/2014, 21:20
Báo cáo y học: " Updating the evidence for the role of corticosteroids in severe sepsis and septic shock: a Bayesian meta-analytic perspective" pot
... papers of potential interest including review papers The published text of 31 ‘randomized’ clinical trials, including seven abstracts from proceedings of scientific meetings, were further reviewed ... forest plot representation of the effect The vertical straight line denotes null effect (odds ratio (OR) = 1) The individual points denote the OR for each study and the lines on either side the ... risks, the probability of an event is more appropriately estimated by the cumulative incidence function, which, for the particular event of interest, is a function of the hazards of all the competing
Ngày tải lên: 13/08/2014, 21:21
Báo cáo sinh học: "Eleven generations of selection for the duration of fertility in the intergeneric crossbreeding of ducks" doc
... unre-lated and not inbred Therefore, the average inbreeding coefficient in G1 was 0 This was also the case in G2, due to the rotational nature of the mating plan in the C line In contrast, full-sib ... and the durations of fertility according to the egg set rates in 1997 (G6), 2001 (G9) and 2005 (G12) for the S line and in 2005 for the C line The R2 were >0.99 indicating the goodness of fit ... her mother, for mating according to the rotational scheme shown in Figure 1[21] In the mating plan, constitutive groups of breeders in the control line for the generation Gn+1 were divided into
Ngày tải lên: 14/08/2014, 13:21
guide for the use of polymers in concrete
... greaterthan the softening point of the polymer The designershould consider the softening point of the particular poly-mer used in relation to the expected service temperature.However, for a typical ... finishedproducts Curing of the formulations for PC patching materials isgenerally referred to as exothermic reaction curing Theworking and curing time for PC is affected by the amount ofthe promoter and initiator ... are often called catalysts in the context of PIC In reality they are not catalysts in the purechemical sense since they are consumed during the polymer-ization reaction Only small amounts of initiators
Ngày tải lên: 24/10/2014, 22:11
The Application of Textiles in Rubber
... mm, inwhich form it is coiled into a large can for passing to the next stage In this form, thecontinuous ‘rope’ of cotton is called a ‘roving’ (4) Drafting: the drafting stage in the spinning ... done using thedistaff to hold the unspun fibres, which were then teased out using the fingers andtwisted into the final yarn on the spindle In the 1530s, in Brunswick, a ‘spinningwheel’ was invented, ... weather on the soldiers from southern Europe In the family context, it generally fell to the female side to undertake the spinning,while the weaving was the domain of the men Spinning was originally
Ngày tải lên: 07/08/2015, 15:14
Bioanalytical strategies for the quantification of xenobiotics in biological fluids and tissues 1
... directly into the environment [13, 14] The major routes by which the aforementioned environmental toxicants enter the body are through the skin, the lungs, and the gastrointestinal tract and they ... be the major source for introduction of PPCPs into the aquatic system PPCPs enter into the environment through individual human activity and as residues from manufacturing, agribusiness, veterinary ... in the environment and increase in Trang 4concentration with time For example, burning of plastics and certain fertilizers forms dioxin, a xenobiotic toxin, so pervasive and it can be found in
Ngày tải lên: 10/09/2015, 09:08
Bioanalytical strategies for the quantification of xenobiotics in biological fluids and tissues 2
... [5-8] Therefore, determining the level of estrogens in these body fluids would be very important for the study of their roles in the carcinogenesis of ovarian and breast cancer The role of estrogen ... was then heat sealed using an electrical sealer to the main sheet The fold-over section was then trimmed off from the main membrane sheet The former was then cut (at ~1.5 cm intervals) into individual ... samples The information regarding the levels of estrogen in tumor ovarian cyst fluids might play an important role in disease diagnostics This work also investigates the feasibility of applying the
Ngày tải lên: 10/09/2015, 09:08
Slide an investigation into some approaches to vocabulary teaching and learning and the application of games in teaching and learning vocabulary at pre – intermediate level at foreign language center – haiphong university
... Rationale Aims of the study Scope of the study Methods of the study Design of the study Research questions: What is the present situation of teaching and learning vocabulary at Pre – Intermediate ... expectation 1.What you think of the games your teachers used in your vocabulary lesson? a b c d Very interesting and useful Rather interesting and useful Interesting and useful Uninteresting and useless ... with one another Games can motivate learners by bringing fun to classes Games are highly motivating because they are amusing and interesting (Ersoz, 2000) By bringing fun to the language...
Ngày tải lên: 29/01/2014, 14:36
Tài liệu OUTLINES OF DAIRY BACTERIOLOGY A CONCISE MANUAL FOR THE USE OF STUDENTS IN DAIRYING docx
... 14 Effect of cooling milk on the growth of bacteria Conn[42] is inclined to regard temperature of more significance in determining the keeping quality than the original infection of the milk itself ... themselves and their excreta taint the air will often result in the absorption of these odors by the milk to such an extent as to seriously affect the flavor The custom of straining the milk in the barn ... stirring up of the same increases the number of organisms to be found in the air (Fig 11) Thus, the feeding of dry fodder and the bedding of animals with straw adds greatly to the germ life floating...
Ngày tải lên: 16/02/2014, 22:20