... improvement in breast cancer survival rate The purpose of this study was therefore to explore the factors influencing resilience in women who completed chemotherapy for breast cancer in the Accra ... systems that influence resilience in women who completed chemotherapy for breast cancer in Accra Metropolis? 4 How do women with breast cancer adapt to breast cancer diagnosis and chemotherapy ... receive chemotherapy Again, this study ‘s findings shall serve as a vital information source for preparing educational materials for clinicians and the general public on factors influencing resilience
Ngày tải lên: 31/07/2019, 00:38
... RIA kit Clinical staging and pathology Clinical breast cancer staging was determined using the 7th edition of the American Joint Committee on Cancer (AJCC) at both institutions At Iowa, institutional ... especially in breast cancer Preclinical data have found that VD impacts the regulation of cancer cell proliferation by intervening on the cell cycle via kinases such as cyclines, cyclin-dependant kinases ... Conclusion: Vitamin D deficiency is associated with the inability to reach pCR in breast cancer patients undergoing NAC Keywords: Vitamin D, Neo-adjuvant breast cancer, pCR Background Neoadjuvant chemotherapy
Ngày tải lên: 03/07/2020, 01:26
Prediction of survival after neoadjuvant chemotherapy for breast cancer by evaluation of tumor-infiltrating lymphocytes and residual cancer burden
... tumor-infiltrating lymphocytes in a phase III randomized adjuvant breast cancer trial in node-positive breast cancer comparing the addition of docetaxel to doxorubicin with doxorubicin-based chemotherapy: ... surrounding environment (cancer microenviron-ment) also influences cancer cells and is involved in the intrinsic characteristics of cancer [13] The tumor im-mune environment not only influences ... evaluated on a single full-face hematoxylin and eosin (HE)-stained tumor section using criteria described by Salgado et al [29] TILs were defined as the infiltrating lymphocytes within tumor stroma
Ngày tải lên: 23/07/2020, 23:58
Validation of the CancerMath prognostic tool for breast cancer in Southeast Asia
... its performance in a Southeast Asian setting Methods: Using Singapore Malaysia Hospital-Based Breast Cancer Registry, clinical information was retrieved from 7064 stage I to III breast cancer ... this model in the Singapore Malaysia Hospital-Based Breast Cancer Registry, demonstrating its predictive performance for different subgroups and determining its calibration and discrimination Methods ... combined databases from three public tertiary hospitals The breast cancer registry at National University Hospital (NUH) in Singapore collects information on breast cancer patients diagnosed since
Ngày tải lên: 20/09/2020, 18:20
Genome-wide association study of susceptibility loci for breast cancer in Sardinian population
... with breast cancer risk at thep < 10−6level Twenty of these regions contained defined genes, including one already associated with breast cancer risk:TOX3 With a lower threshold for preliminary ... Sardinia (Italy) In Sardinia, breast cancer represents the principal death-causing malignancy among women, with an in-cidence similar to that observed in other western populations [10] The Sardinian ... such a case–control GWA study for breast cancer risk in our collection of Sardinian breast cancer patients who are negative for BRCA1 or BRCA2 mutations Methods Breast cancer cases and controls From
Ngày tải lên: 30/09/2020, 10:53
Obesity is a significant risk factor for breast cancer in Arab women
... available on the breast cancer risk factors for the Arab population Therefore, in an attempt to identify and better define these risk factors for breast cancer among Arab women, we initiated the ... <0.0001), indicating two-half fold in-crease in breast cancer risk among obese premenopausal patients (Table 2) In the post-menopausal females, obese women have 66% increase chance of breast cancer ... [29,35-37] Further investigations are recommended to understand the underlying mechanisms of the influ-ence of breastfeeding on breast cancer It is well established that breast cancer risk increases with
Ngày tải lên: 30/09/2020, 14:41
Patient and physician factors associated with Oncotype DX and adjuvant chemotherapy utilization for breast cancer patients in New Hampshire, 2010-2016
... to examine multiple outcomes: use of ODX, being recommended chemotherapy following ODX, receiv-ing chemotherapy followreceiv-ing ODX, and chemotherapy refusal following ODX We further examined ... total variance in chemotherapy use, respectively For all patients tested with ODX, clustering within physicians and within hos-pitals accounted for 18 and 4% of variation in receiving chemotherapy, ... regarding physi-cians caring for Medicare eligible patients in the United States [36] Study cohort and definitions Our study cohort includes women residing in New Hampshire and diagnosed with breast
Ngày tải lên: 28/09/2020, 09:41
Retrospective and comparative analysis of 99mTc-Sestamibi breast specific gamma imaging versus mammography, ultrasound, and magnetic resonance imaging for the detection of breast cancer in
... semi-quantitative value of BSGI in breast cancer diagnosis possible Interestingly, Fig 5 Images for the case of breast cancer patient with TRN = 12.75 a MMG for right breast b US for right breast and axillary ... leading type of new cancer cases and the second leading cause of cancer related deaths in fe-males worldwide [1] During the past 30 years, the inci-dence and mortality of breast cancer in Chinese ... Chinese women, particularly for ductal carcinoma in situ (DCIS), mammographic breast density and non-luminal A breast cancer Keywords: Breast specific gamma imaging, Breast cancer, Sensitivity, Specificity
Ngày tải lên: 21/09/2020, 01:57
The treatment patterns, efficacy, and safety of nab® -paclitaxel for the treatment of metastatic breast cancer in the United States: Results from health insurance claims analysis
... and Drug Admin-istration in January 2005 for the treatment of breast cancer after failure of combination chemotherapy, includ-ing anthracyclines, for metastatic disease or relapse within 6 months ... data in the clinical trial setting In addition, claims data for analysis tend to bias toward underreporting in comparison with prospective National Cancer Institute Common Terminology Criteria for ... breast cancer with patients with MBC, missing information on hormone receptor status, mis-interpreting disease-onset dates, misclassifying the line of therapy, and inaccurately estimating actual
Ngày tải lên: 21/09/2020, 10:20
Patterns of resource utilization and cost for postmenopausal women with hormonereceptor–positive, human epidermal growth factor receptor-2–negative advanced breast cancer in Europe
... HT-refractory b in 1st line ( n = 107) HT-eligible c in 2nd line ( n = 248) Total cost difference (over 3 lines of therapy)d HT instead of CTx in 1st line €14 362 €7300 NA HT instead of CTx in 2nd line €10 ... same line of treatment, with a notable increase during second-line treatment for cohort A (41 % for chemotherapy) com-pared with first-line treatment (19 % for hormone ther-apy) Additionally, in ... Adjuvant drug therapies, n (%) First-line ABC setting, n (%) Second-line ABC setting, n (%) Third-line ABC setting, n (%) Trang 6chemotherapy in the same treatment settings (Table 5).Furthermore, substantial
Ngày tải lên: 22/09/2020, 23:58
Real-world patient-reported outcomes of women receiving initial endocrine-based therapy for HR+/HER2− advanced breast cancer in five European countries
... participating in a clinical trial Data for this Ad-vanced Breast Cancer DSP were collected between March and July 2017 at a single time point for each par-ticipating patient and physician in France, ... items related to pain severity (worst pain in last 24 h, least pain in last 24 h, average pain in last 24 h, pain right now) and seven items related to interference by pain in the past 24 h (general ... addressed include the optimal initial therapy for advanced disease and the sub-sequent sequence of treatments for delaying disease pro-gression and improving/maintaining the HRQoL of those living with
Ngày tải lên: 28/09/2020, 09:29
Internet-based cognitive behavioral therapy for sexual dysfunctions in women treated for breast cancer: Design of a multicenter, randomized controlled trial
... sexuality and breast cancer of The Netherlands Cancer Institute Unpublished manuscript] that was conducted in women who attended an informational meeting of a sexu-ality and breast cancer clinic, but ... effect-iveness of online CBT for FSD in the general population [76], and of an online intervention for sexual problems in breast cancer survivors [81] However, the efficacy of an internet-based CBT for sexual ... available in this article, Trang 2Breast cancer is the most common type of cancer among women in the Netherlands [1] Improved breast cancer screening and treatment have resulted in increased
Ngày tải lên: 29/09/2020, 16:10
Eligibility criteria for intraoperative radiotherapy for breast cancer: Study employing 12,025 patients treated in two cohorts
... available in this Trang 2Breast cancer (BC) is the leading cancer worldwide in terms of incidence, with 1.38 million new cases diag-nosed in 2008 (23% of all cancers) It is now the most frequent cancer ... restrictive in the RIOP trial) Magnetic resonance imaging (MRI) of the breast was not indispensable for inclusion in the pre-sent study Nevertheless, one must question the value of MRI for disqualifying ... (Radiothérapie IntraOPératoire) trial (RIOP is a trial being carried out in France, coordina-ted by the Institut René Gauducheau and it is being conducted under the aegis of the Institut National du Cancer)[5]
Ngày tải lên: 30/09/2020, 15:12
Development and validation of a questionnaire to assess delay in treatment for breast cancer
... where the interviewers administered the questionnaire to breast cancer patients in the presence of KUS The patients who were interviewed in the training stage were not included in the final analysis ... argued in the discussion section, this find-ing could be an effect of the passage of time Best time for the interviews After testing different moments for performing the interviews, we determined ... are much lower than in developed coun-tries, mainly because cancer is diagnosed in later stages For instance, in the United States, 60% of breast cancer cases are diagnosed in stages 0 and I,
Ngày tải lên: 05/11/2020, 08:13
báo cáo khoa học: "Complications after radical gastrectomy following FOLFOX7 neoadjuvant chemotherapy for gastric cancer" pdf
... without nodal involvement as determined by physical examination, imaging and endoscopy Although clinical staging before treatment was similar in the two groups, pathologic staging (according to the ... remains to be determined Various regimens of neoadjuvant chemotherapy in gastric cancer have been shown to induce tumour responses [4] But the potential accompanied disadvantages, including increased ... gastric cancer [3] Up to this point, many neoadjuvant chemotherapy treatments for gastric cancer have been used with varying success to downstage locally advanced gastric cancers [4], and finding
Ngày tải lên: 09/08/2014, 02:21
báo cáo khoa học: "Free Rhodium (II) citrate and rhodium (II) citrate magnetic carriers as potential strategies for breast cancer therapy" docx
... of actin filaments in MCF-7 breast carcinoma cells 48 hours after treatment Cells were stained with DAPI (4 ’,6-diamidino-2-fenilindol) to visualize the nucleus (in blue) and with Phalloidine-Alexa ... Phosphatidylserine exposition on breast carcinoma cells In Figure 7 the percentage of cells that were positively stained for annexin V-FITC is represented After 500 μM Rh2(H2cit)4 treatment, the annexin-V+ ... 4 ) in breast carcinoma cell lines (MCF-7 and 4T1) and breast normal cell line (MCF-10A) Cells were incubated with free rhodium (II) citrate (Rh 2 (H 2 cit) 4 ), Magh-Rh 2 (H 2 cit) 4 (final
Ngày tải lên: 11/08/2014, 00:23
Outcome after breast cancer in singapore and malaysia
... Literature Review Breast cancer in South East Asia Screening for breast cancer Clinical investigations of breast cancer Treatment of breast cancer Prognostic indicators of breast cancer Lymph node ... breast cancer with special attention being paid to breast cancer in Singapore and Malaysia Breast cancer in South East Asia Developing countries have seen a rapid rise in breast cancer incidence ... chance of missing out the cancer Trang 37 Clinical examination and Imaging were discussed in detail under the heading ―Screening for breast cancer‖ Breast Biopsy Breast biopsy is performed once
Ngày tải lên: 09/09/2015, 17:55
Health services research on endoscopic surveillance for gastric cancer in the singapore chinese population experience of the gastric cancer epidemiology clinical and genetic program
... in gastric cancer mortality and incidence for males 11 Figure 1-7 Declining trends in gastric cancer mortality and incidence for females 12 Figure 2-1 Carcinogenesis for Gastric Cancer 19 ... gastric cancer in the stomach (2003-2007) 2 Table 1-2 TNM staging system for gastric cancer 4 Table 1-3 Clinical staging system for gastric cancer 6 Table 1-4 Basic statistics of gastric cancer in ... Figure 2-2 Clinical consequences of H pylori infection Given the role of H pylori infection in GC development, intuitively, eradicating this infection would eliminate cancer risk before precancerous
Ngày tải lên: 10/09/2015, 09:07
Liposomal co encapsulation of quercetin with synergistic chemotherapeutic drugs for breast cancer treatment
... QUERCETIN AND VINCRISTINE IN THE PLASMA OF BALB/C MICE AFTER INTRAVENOUS ADMINISTRATION OF FREE COMBINATION OF QUERCETIN AND VINCRISTINE OR QUERCETIN AND VINCRISTINE CO- ENCAPSULATED IN LIPOSOMES ... VINCRISTINE/QUERCETIN OVER TIME FOR FREE VINCRISTINE AND QUERCETIN COMBINATION (■) AND VINCRISTINE/QUERCETIN IN CO-ENCAPSULATED LIPOSOMES (♦) IN PLASMA THE DOTTED LINE REPRESENTS THE INITIAL ... TREATED VIA TAIL VEIN INJECTIONS WITH VEHICLE BUFFER (♦), QUERCETIN (■), VINCRISTINE (▲), QUERCETIN AND VINCRISTINE AS FREE FORM (X) AND CO-ENCAPSULATED QUERCETIN AND VINCRISTINE IN LIPOSOMES (∆)
Ngày tải lên: 11/09/2015, 10:07
Báo cáo sinh học: " Encapsulation of docetaxel in oily core polyester nanocapsule intended for breast cancer therapy" pptx
... publishing your research in Nanoscale Research Letters go to http://www.nanoscalereslett.com/authors/instructions/ For information about other SpringerOpen publications go to http://www.springeropen.com Nanoscale ... SK, Li Y, Jennings NB, Fan D, Nelkin GM, Schmandt R, Schaller MD, Sood AK: Focal adhesion kinase silencing augments docetaxel-mediated apoptosis in ovarian cancer cells. Clin Cancer Res 2005, ... drug loading. Background In cancer therapy, most of the proposed formulations present certain drawbacks related to the formulation properties including low drug loading, toxicity, and unsuitable...
Ngày tải lên: 18/06/2014, 22:20