... on stimulation and infection with RML brain homogenate (Fig 5) In J774 n i co CpG-ODN LPS 5838 Fig PrPSc is located intracellularly in J774 and BV-2 cells BV-2 (left panel) and J774 (right panel) ... dependent on the prion strain used for infection [33,34] Microglial cells can contain infectivity in vivo and may disseminate prion infectivity within the brain during their migratory activities ... stimulated J774 cells as indicated and incubated them with RML brain homogenate Cells were lysed directly, or incubated for a further 24 h in culture medium either with or without suramin (Fig 6C)
Ngày tải lên: 07/03/2014, 05:20
... organizing, and printing projects Calling the STEP 7 online help Setting the window display and arrangement, selecting the language, and making settings for process data Editing blocks and inserting ... with STEP 7 Detailed instructions in the individual chapters will show you step-by-step the many ways in which you can use STEP 7 Creating a Program with Binary Logic In Chapters 2 to 7, you will ... Installing STEP 7 Regardless of whether you want to start with programming or configuring hardware, you first have to install STEP 7 If you are using a SIMATIC programming device, STEP 7 is already installed
Ngày tải lên: 29/03/2014, 12:20
Báo cáo y học: "Bullying in school and cyberspace: Associations with depressive symptoms in Swiss and Australian adolescents" docx
... associated with externa-lizing problems, while being a victim of bullying is strongly associated with internalizing symptoms Consequences and correlates of bullying and cyber-victimisation The existing ... bullying behaviors and psychosocial adjustment Archives of Pediatrics and Adolescent Medicine 2004, 158:730-736. 28 Perren S, Hornung R: Bullying and Delinquency in Adolescence: Victims ’ and ... 2007, 43:564-575. 38 Slonje R, Smith PK: Cyberbullying: Another main type of bullying? Scandinavian Journal of Psychology 2008, 49:147-154. 39 Ybarra ML, Mitchell KJ: Youth engaging in online
Ngày tải lên: 13/08/2014, 18:21
Magnetic resonance spectroscopy correlation with histological analysis in gliomas and structure determination of a hypothetical protein
... reaction kinetics and intra-molecular dynamics of macromolecules Additionally, NMR is efficient in determining ligand binding and mapping interaction surfaces of protein/ligand complexes Since first ... reduced in the brain of patients with brain tumor or infectious brain masses (Wang, 1998) In vivo NMR measurements in brain observe the total of both creatine and phosphocreatine as prominent singlet ... Consequently, only spin systems within individual amino acids can be obtained in proton spectrum In proteins which are labeled with 15N and 13C, J couplings between 1H, 15N and 13C allow through-bond
Ngày tải lên: 10/11/2015, 11:35
A key genomic signature associated with lymphovascular invasion in head and neck squamous cell carcinoma
... drug–module interactions (XL844, AT7519, AT9283, alvocidib, and nelarabine) in the turquoise module and three drug–module interactions (benzamidine, L-glutamine, and zinc) in the pink module could ... metastasis in patients with HNSCC According to recent studies, the clinical characteristics of and parameters contributing to LOI remain uncertain In fact, the incidence of LOI in patients with HNSCC ... the pink module in the biological process category Trang 8in head and neck cancer have been conducted (Additionalfile 7: Table S7) Moreover, XL844 (NCT00475917), AT7519 (NCT00390117, NCT02503709),
Ngày tải lên: 17/06/2020, 11:24
Tumoral BRD4 expression in lymph nodenegative breast cancer: Association with Tbet+ tumor-infiltrating lymphocytes and disease-free survival
... EGFR The luminal subtype was subsequently distinguished into luminal A and luminal B based on PgR, p53 status and Ki-67 labeling index Tumors with a Ki-67 labeling index of ≥14% and were negative ... (Bromodomain-Containing Protein 4), a member of the Bromodomain and Extra Terminal domain (BET) family, as a gene that distinguished T-bet+/high and T-bet−/low tumors In clinical studies, BET inhibitors ... notably via activating NF-kB-regulated pathways in cancer cells [17] NF-kB is a major transcription factor involved in regulating immune and inflammatory responses, and in influencing cancer progression
Ngày tải lên: 03/07/2020, 01:13
Feasibility and acceptability of combining cognitive behavioural therapy techniques with swallowing therapy in head and neck cancer dysphagia
... life without eating and drinking (n = 1) x x x x x x x x Feel better about changes to eating and drinking (n = 2) x x x x x x Become more confident about eating (n = 4) x To increase eating amount ... recovery and well-being Patients liked the combination of talking, visualising issues using a whiteboard and other applied techniques, and concrete goal setting ‘Maybe it should be part of the initial ... Competing interests The authors declare that they have no competing interests Publisher’s Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional
Ngày tải lên: 23/07/2020, 23:44
Prognostic value of S1PR1 and its correlation with immune infiltrates in breast and lung cancers
... angiogenesis and tumor growth [13] Studies have shown that S1PR1 inhibits VEGF signaling by pro-moting the interaction between VE-cadherin and VEGFR2, thereby inhibiting VEGF-induced vascular sprouting ... S1PR1 in breast and lung cancers Gene expression data of breast invasive carcinoma (BRCA), lung adenocarcin-oma (LUAD) and lung squamous cell carcinadenocarcin-oma (LUSC) in TCGA were downloaded and ... expression levels and levels of infiltrating CD8+ T cells (r = 0.279, P = 1.76e-03) and CD4+ T cells (r = 0.237, P = 8.52e-03) Similarly, there were positive correlations with infil-trating levels of
Ngày tải lên: 19/09/2020, 22:14
Bullying in school and cyberspace: Associations with depressive symptoms in Swiss and Australian adolescents
... of bullying: traditional bullying, including physical or verbal harassment, exclusion, relational aggression and cyber-bullying, involving the use of some kind of electronic media (i.e., Internet ... strongly associated with externalizing problems, while being a victim of bullying is strongly associated with internalizing symptoms Consequences and correlates of cyber-bullying and cybervictimisation ... internalizing (and externalizing) problems However, as traditional and cyber-bullying forms are strongly associated and frequently co-occur within the same individuals [1,36-39] it is important to investigate
Ngày tải lên: 22/10/2020, 21:50
Identification of FISH biomarkers to detect chromosome abnormalities associated with prostate adenocarcinoma in tumour and field effect environment
... number gain with DAPI staining (A) showing the nuclei morphology, and MYC staining (B) displaying gain of copy numbers C and D: the images of PTEN loss with DAPI staining (C) of the tumour ROI, and ... for 3 minutes in deionized water, incubated 20–22 minutes in 0.15% pepsin in 0.1 N HCl solution at 37°C, and rinsed again for 3 minutes in deionized water Slides then were dehydrated for 1 minute ... abnormalities in most RP specimens, both within tumour regions and extending beyond histologically evident tumour The six probes in-cludedMYC, LPL, CEP8, PTEN, CEP10, and CEP7 We expanded the initial
Ngày tải lên: 05/11/2020, 01:22
Ellipsis in complex sentences in the novel “gone with the wind” in english and their vietnamese equivalents in translated version
... - 2020 MINISTRY OF EDUCATION AND TRAINING HANOI OPEN UNIVERSITY M.A THESIS ELLIPSIS IN COMPLEX SENTENCES IN THE NOVEL “GONE WITH THE WIND” IN ENGLISH AND THEIR VIETNAMESE EQUIVALENTS IN TRANSLATED ... translation of ellipsis in complex sentences in English literary works into Vietnamese In this thesis some challenges in teaching, learning ellipsis and translating elliptical elements into Vietnamese ... sentences in the novel “Gone with the wind” in English and their Vietnamese equivalents in translated version by Vu Kim Thu 31 4.2 English elliptical noun phrase in the novel “Gone witht the Wind” and
Ngày tải lên: 22/12/2020, 00:46
Ellipsis in complex sentences in the novel “gone with the wind” in english and their vietnamese equivalents in translated version
... - 2020 MINISTRY OF EDUCATION AND TRAINING HANOI OPEN UNIVERSITY M.A THESIS ELLIPSIS IN COMPLEX SENTENCES IN THE NOVEL “GONE WITH THE WIND” IN ENGLISH AND THEIR VIETNAMESE EQUIVALENTS IN TRANSLATED ... translation of ellipsis in complex sentences in English literary works into Vietnamese In this thesis some challenges in teaching, learning ellipsis and translating elliptical elements into Vietnamese ... sentences in the novel “Gone with the wind” in English and their Vietnamese equivalents in translated version by Vu Kim Thu 31 4.2 English elliptical noun phrase in the novel “Gone witht the Wind” and
Ngày tải lên: 07/02/2021, 15:04
comparative phylogeography of two related plant species with overlapping ranges in europe and the potential effects of climate change on their intraspecific genetic diversity
... agarose gels and visualised by ethidium bromide staining, and the remaining 15 μl sequenced in both directions using the BigDye sequencing kit (V3.1; Applied Biosystems) and run on an AB 3730XL DNA ... -England ENPE 0.624 - 6 - - - 6 - -Estonia EEJO 0.690 - 6 - - - 6 -EEPO 0.573 7 - - - 8 -Ireland IEEL 0.500 8 - - - 7 - -IEST 0.370 8 - - - 7 - -Poland PLCL 0.516 - - 8 - - - - 7 - -PLLG 0.716 ... 421:37-42. Fingerprints of global warming on wild animals and plants Nature 2003, 421:57-60. change Ann Rev Ecol Evol Syst 2006, 37:637-669. Collingham YC, Erasmus BFN, de Siqueira MF, Grainger
Ngày tải lên: 02/11/2022, 08:49
phenotypic histological and proteomic analyses reveal multiple differences associated with chloroplast development in yellow and variegated variants from camellia sinensis
... transport, and 5 proteins in LHC; whereas between HY2 and CK2, 14 proteins, including 5 proteins in PSI, 5 proteins in PSII, 2 proteins in the cytochrome b6/f complex, 1 protein in the F-type ATPase, and ... and 170 proteins increased in HY1 and HY2, respectively (Tables S6 and S7) For example, as shown in Fig. 3, the expression of chlorophyll a-b binding proteins, heat shock proteins and proteins ... expressed proteins were associated with photosynthesis between HY1 and CK1, including 4 proteins in PSI, 3 proteins in PSII, 1 protein in the cytochrome b6/f complex, 1 protein in the photosynthetic
Ngày tải lên: 04/12/2022, 16:07
Coping with Chronic Illness in Childhood and Adolescence
... Coping with Chronic Illness: Fundamental IssuesDefining and conceptualizing coping After considerable debate and confusion, some consensus is slowly emerging regarding thedefinition of coping in ... self-isolation and catastrophizing (which cross-loaded with active coping in the original factoranalyses), and stoicism and acceptance (which cross-loaded with accommodative coping in Trang 7the original ... (3–4 times per day or use of an insulinpump), monitoring and controlling carbohydrate intake, altering insulin dose to match dietand activity patterns, and checking urine for ketones when necessary
Ngày tải lên: 02/02/2024, 08:25
A contrastive analysis of idioms denoting humans with dispraising implications in english and vietnamese
... - Investigating syntactic, stylistic and semantic features of IDHDIE and IDHDIV - Finding out the similarities and differences between IDHDIE and IDHDIV - Making some suggestions for teaching, ... Trang 1MINISTRY OF EDUCATION AND TRAINING UNIVERSITY OF DANANG TRƯƠNG THỊ BÍCH HỒNG A CONTRASTIVE ANALYSIS OF IDIOMS DENOTING HUMANS WITH DISPRAISING IMPLICATIONS IN ENGLISH AND VIETNAMESE ... languages and showing an essential relationship between language and culture + Inspiring the love of the Vietnamese language and culture to English-speaking people when learning Vietnamese and vice
Ngày tải lên: 26/11/2013, 13:31
Network administration with FreeBSD 7 building securing and maintainning network with the FreeDBS operating system
... Trang 2Network Administration with FreeBSD 7Building, securing, and maintaining networks with the FreeBSD operating system Babak Farrokhi Trang 3Network Administration with FreeBSD 7Copyright © 2008 ... both client and server Chapter 10 has a closer look at routing and bridging in FreeBSD using built-in bridging features and also different routing protocols including OSPF and BGP using third-party ... virtualization in FreeBSD and introduces Jails from ground up This chapter covers creating and maintaining Jails and scenarios in which you can benefit from these built-in virtualization facilities in FreeBSD
Ngày tải lên: 07/04/2017, 16:34
Impact of obstructive sleep apnea on lung volumes and mechanical properties of the respiratory system in overweight and obese individuals (download tai tailieutuoi com)
... resistance and peripheral airway resistance significantly increase, and its inverse Grs decrease, in obese patients with OSA in comparison with those without OSA, and are independently associated with ... measurements and severity of OSA Figure 3a and b show that significant increases in R0, Zrs5 and R5 and a decrease in Grs were found with in-creasing severity of OSA among male subjects and those ... chin, electrocardiogram, and recording of snoring and body position, respiratory efforts were de-tected with ribcage and abdominal piezo belts, oxygen sat-uration using pulse oximetry, according
Ngày tải lên: 23/10/2022, 16:34
Matematik simulation and monte carlo with applications in finance and mcmc phần 7 ppt
... of 4.1708 and standard error of 0.00037 using 100 replications, each consisting of 2500 replications over 100 strata, as given in Table 6.2. Bearing in mind the different sample sizes and the ... Z1 and Z2 are independent standard normal random variables and 1 and 2 are... replacement is better when cp =cf < 6 37= 2500 Problem 1.4 2 Two points A and B are selected randomly in ... strike price K and exercise time T , on an underlying asset having an initial price S 0 which earns interest continuously at rate q with constant volatility s, and where the risk-free interest rate
Ngày tải lên: 09/08/2014, 16:21
Study of Epstein Barr virus, human Herpes 6 and human herpes 7 in children with acute Lymphoblastic leukemia
... between EBV and HHV6 infection in patients (P=0.001) (Figure 1) There was increase in the prevalence of EBV (36.8%), HHV6 (40%) and HHV7 (75%) in age above 4 years, however the increase were insignificant ... Simpore J.EBV and HHV-6 Circulating Subtypes in People Living with HIV in Burkina Faso, Impact on CD4 T cell count and HIV Viral Load Mediterr J Hematol Infect Dis 2017 Sep 1;9(1):e2017049 doi: 10.4084/ ... Epestein Barr virus (EBV), Human Herpes virus 6 (HHV6)and Human Herpes virus 7 (HHV7) by molecular methods in newly diagnosed ALL in children and to correlate their presence with clinical and
Ngày tải lên: 14/01/2020, 19:46
Bạn có muốn tìm thêm với từ khóa: