ascs for adipose tissue reconstruction and transplantation

... via the lipoprotein system [5,6] Tissue- distribution studies have shown that B[a]P accumulates in lipid-storing tissues including the mammary glands and adipose tissue The carcinogenicity of B[a]P ... essential for processing B[a]P [36] A study monitoring the kinetics of B[a]P and other pollutants in both overweight and obese subjects before and during weight loss would provide useful information ... Indeed, b1- and b2-adrenergic receptors are predominant in human adipocytes, whereas b3-adrenergic receptor activity is predominant in rodent brown and white adipose tissue We therefore sought...

Ngày tải lên: 30/03/2014, 11:20

... bioengineering and transplantation Endogenous and exogenous stem and progenitor cells for lung repair The airway epithelium is subjected to a lifetime exposure by inhaled particles and pathogens ... containing a cell-binding site for ligation of cell-surface integrin receptors and substrates for MMPs, proteases implicated in wound healing and tissue regeneration [51,52] and fabrication of scaffolds ... and trauma Rejuvenation Res doi:10.1186/1423-0127-17-92 Cite this article as: Chistiakov: Endogenous and exogenous stem cells: a role in lung repair and use in airway tissue engineering and transplantation...

Ngày tải lên: 10/08/2014, 05:21

... phenotypic stability of differentiated cells and tissues, delivery systems and biomaterials for cartilage repair, and survivability and integration of the tissue graft to the host cartilage This review ... addition, biomaterials may also provide physical cues for cell orientation and spreading, which are critical for hESC differentiation and tissue formation For example, co-cultured hESC-derived chondrogenic ... homogenous cartilaginous tissue, with good tissue growth and an absence of teratoma formation The cartilaginous tissue formed also displayed high levels of collagen type I and II, as well as some...

Ngày tải lên: 11/09/2015, 09:57

... melanin and cytochrome will be ignored 2.3 Optical properties of breast tissues The human breast tissues are majorly constituted by glandular tissue and fatty tissue The concentrations of water and ... breast tissues Meanwhile, its effect will increase with women ageing because older women tend to have less fibrous tissue and more adipose tissue 2.2.3 Hemoglobin Oxyhemoglogin (HbO) and deoxyhemoglobin ... resolution and signal to noise ratio, fast data acquisition speed and stable performance • to design an optical hand-held probe and the detection geometry • to develop advanced image reconstruction...

Ngày tải lên: 12/09/2015, 11:35

... devices and polymers used as nerve conduits) Nanotechnology and nanomaterials: Promises for improved tissue regeneration used for neural tissue repair have been limited by the extensive formation ... vitronectin and laminin) adsorption and bioactivity before cells adhere on implants, further regulating cell behavior and dictating tissue regeneration [12] Furthermore, an important criterion for designing ... conventional materials for tissue growth Therefore, by controlling surface properties, various nanophase ceramic, polymer, metal and composite scaffolds have been designed for bone/cartilage tissue engineering...

Ngày tải lên: 20/03/2014, 13:05

... locations and consists of two major forms: white adipose tissue (WAT) and brown adipose tissue (BAT) WAT is the main site for the storage of energy in the form of triglycerides located in large lipid ... renewed interest in understanding its formation and function Differentiation of white and brown preadipocytes Changes in adipose tissue mass as a result of genetic and environmental factors involve ... white and brown depots Adipose tissue is the most abundant tissue in humans, representing approximately 10–29% of body weight It is found in a multitude of locations and consists of two major forms:...

Ngày tải lên: 29/03/2014, 22:21

... of adipose tissue consistently point to the microvasculature and angiogenesis within adipose tissue as critical role players in adipose tissue health and expansion [3] Expansion of adult adipose ... an important player in adipose tissue circulation and will discuss the interactions between the lymphatic circulation and adipose tissue later in this minireview Adipose tissue angiogenesis Studies ... of existing adipose tissue may result in increased levels of inflammation Adipose tissue and tumor growth Although adipose tissue vascularization functions in a delicate balance in tissue homeostasis,...

Ngày tải lên: 29/03/2014, 22:21

... give informed consent Figure Inclusion and exclusion criteria of the study time, blood loss, requirement for blood products, incision-to-suture time) and donor data (age, serum sodium and gamma-GT ... intensive care unit before and for at least 48 hours after the cell infusion (see Figure 4) Follow-up Thirteen follow-up visits will be performed during the first 30 days after transplantation Blood ... examinations performed, and adverse events recorded as detailed in Table Dose-limiting toxicity (DLT) assessments will be performed on days 1, 2, 3, 4, 10, and 30 Per protocol, biopsies will be performed...

Ngày tải lên: 18/06/2014, 22:20

... durations, numbers, and fre- Table 1: Patient and wound details before and after negative pressure wound therapy No Age Sex Injury Site Wound grade (before) Wound grade (after) Size (before) Size (after) ... confirming the formation of healthy granulation tissue Skin grafting was performed when further coverage was required Wound types (acute or traumatic versus chronic) and location were noted, and durations, ... NPWT helps healing and whether the technique can reduce the need for flap surgery for the treatment of acute or chronic open wounds in the foot and ankle region Materials and methods Over the...

Ngày tải lên: 20/06/2014, 01:20

... contributions Hou ZQ, Yi YF, and Zhang QQ conceived of the study and participated in the design of the study and performed the statistical analysis and drafted the manuscript Zhan CM and Jiang QW carried ... dark condition for h, and a yellow FA-NPs suspension was obtained The FA-NPs were collected by centrifugation at 12,000 rpm for 30 min, and the deposit was washed with distilled water and centrifuged ... decanted, and the NPs were dispersed in M HCl for 12 h and then dialyzed against the distilled water until the pH near 7.0 in order to remove the excess NaBH4, STPP, and glutaraldehyde Preparations and...

Ngày tải lên: 20/06/2014, 22:20

... pain more difficult and led to patients suffering Assessments of patients for opioids and wise use will begin to reverse this trend 194 Many patients with soft -tissue problems and non-operable osteoarthritis ... the benefits of treatment and informed choice Conclusion Patients still require pain relief; all NSAIDs/Cox-2 inhibitors have cardiovascular and renal side-effects, and the older NSAIDs have ... P, et al.: EULAR evidence based recommendations for the management of hip osteoarthritis: report of a task force of the EULAR Standing Committee for International Clinical Studies Including Therapeutics...

Ngày tải lên: 09/08/2014, 07:20

... slightly modified from those used earlier [19], are r = for lung, and r = 0.825 for breast (values used earlier were r = 0.96 for lung, and r = 0.76 for breast, the current values give slightly better ... of tissue receiving ≥ 4Gy) [5,8,22,23] and bilateral lung V5 [22] V30 for the whole heart was also calculated [23] Second cancer risk modeling Given a dose-volume histogram (DVH) for a normal tissue ... risk reduction Following RT for HL, breast and lung cancer account for the greatest burden of excess risk [1] The estimated ERRs for radiation-induced breast cancer and lung cancer in never-smokers...

Ngày tải lên: 09/08/2014, 10:21

... collecting and contributing tissue samples We also thank Alicia Bertles (USDA, BFGL) for RNA standardization and Keith Moon (Illumina, Inc., formerly Solexa) for cDNA synthesis and next generation sequence ... website, and database schema GPH, TSS, TPLS, and LJA developed the concept of the BGA resource and wrote the manuscript LJA collected the Hereford tissues and extracted total RNA TSS standardized ... endocrine (BRENDA [6,7] gland), alimentary (BRENDA viscus), and nervous tissues that provide for a wide diversity in expression profiles In addition, muscle and fat depots from adult and juvenile steers...

Ngày tải lên: 09/08/2014, 22:23

... analysis Tissue and 3T3-L1 metabolite extraction Metabolites were extracted from white adipose tissue and 3T3-L1 cells using a modified Bligh and Dyer method [33] Frozen white adipose tissue (approximately ... activate PPARδ in both the mice and the adipocyte cell line (GW610742 EC50 for murine PPARδ is 28 nM compared to 8,900 nM for PPARa and > 10,000 nM for PPARg) [12] and contrasted with a well defined ... of triglycerides and glucose in white adipose tissue and systemic metabolism as a whole However, this metabolic systems biology approach also suggests that increased demand for branched chain...

Ngày tải lên: 09/08/2014, 23:20

... extracted and separated by gravity The resulting 100 cm3 of adipose tissue was then centrifuged at 3500 rpm for five minutes The end result was approximately 40 cm3 of packed adipose tissue, fibrous tissue, ... increased pain when standing and walking (VAS score 9) For a week prior to liposuction, she was restricted from taking corticosteroids, aspirin, NSAIDs, and oriental herb medications For the liposuction ... solution (ACD) formula This was centrifuged at 200 g for five minutes The resultant supernatant was drawn and centrifuged at 1000 g for five minutes The supernatant was drawn and discarded The...

Ngày tải lên: 10/08/2014, 23:21

... ligands for both toll-like receptors (TLR) and 4, two major inflammatory receptors in adipose tissue [12,13 ] We demonstrate herein, for the first time, that SLPI is upregulated in adipose tissue ... Epididymal adipose tissue was obtained by careful dissection of adipose tissue around the epididymis and used for RNA extraction with Trizol (Invitrogen, Carlsbad, CA) or tissue lysates for western ... epididymal tissue of mice on high fat diet, visceral (mesenteric and subcutaneous) vs subcutaneous depot and in stromal vascular cells vs adipocytes and whole adipose tissue (Figures 2A, B and 2C)...

Ngày tải lên: 11/08/2014, 03:20

... nerves in the adipose tissue of the painful sites [1,20], which has only been confirmed in one case report [21] As regards inflammatory signs in the adipose tissue in DD, leukocytes and plasma cells ... of patients, and compare them with healthy, obese, body mass index (BMI)-matched controls and controls with normal BMI Patients and Methods Patients A total of 53 women with adipose tissue pain ... reactions in adipose tissue in all groups are summarised in Table Plasma cells were found in very few of the biopsies There was no difference between adipose tissue from painful and non-painful...

Ngày tải lên: 11/08/2014, 03:20

... ligands for both toll-like receptors (TLR) and 4, two major inflammatory receptors in adipose tissue [12,13 ] We demonstrate herein, for the first time, that SLPI is upregulated in adipose tissue ... Epididymal adipose tissue was obtained by careful dissection of adipose tissue around the epididymis and used for RNA extraction with Trizol (Invitrogen, Carlsbad, CA) or tissue lysates for western ... epididymal tissue of mice on high fat diet, visceral (mesenteric and subcutaneous) vs subcutaneous depot and in stromal vascular cells vs adipocytes and whole adipose tissue (Figures 2A, B and 2C)...

Ngày tải lên: 11/08/2014, 06:22