antihypertensive properties of plant protein derived peptides

... history of plants means that the mechanical properties of their load-bearing elements, i.e the plant fibres, are highly optimised with respect to the mechanical requirements of plants Moreover, plant ... critical aspect in the use of plant fibres; i.e their properties are less controllable in comparison to the properties of synthetic fibres The axial tensile properties of the composites are affected ... their properties have therefore been highly optimised with respect to the functional requirements of plants Thus, the study of plant fibre mechanical properties is not just an assessment of the

Ngày tải lên: 13/01/2020, 17:50

... development of a graphitic nano-structure[43] The growth of the D + D’ and 2D’ bands near 2930 and 3200 cm1, respectively, is one more proof of the formation of a defective graphitic nature of PFe ... val-ues of electrical conductivity of the studied samples may be mainly attributed to the combination of the graphitisation degree of the carbon materials and of the relative amounts of N6, N5 ... layers are stacked The appearance of two small peaks instead of a broad one in the 2nd-order part of the spectra of PNiH900 and PFeD800 suggests the better organisation of these materials with respect

Ngày tải lên: 11/05/2020, 10:49

... capability of protein is defined as the amount of oil that can be absorbed per gram of protein (Lin & Zayas, 1987) The oil absorption capacity of protein is influenced by particle size, protein ... functional properties of modified protein from lima bean (Phaseolus lunatus) using Transglutaminase” with the aim of studying the potential application of this type of protein in the field of food ... modification of lima bean protein However, there are studies on the modification of other bean proteins, including research on improving the technological functional properties of isolated mung bean proteins

Ngày tải lên: 07/06/2024, 16:26

... composition - The biochemical properties of sericin: • Evaluation of the antioxidant activity of sericin (ABTS) - The physicochemical properties of sericin: • Evaluation of Isoelectric point (pI) ... moisture, ash, lipids, protein, and carbohydrates content Investigation of different types of acid extraction solvents - The chemical properties of sericin: • Evaluation of the amino acid composition ... industry.Layout of the researchThe report "Effects of acid solvents on properties of sericin protein extracted from silk cocoon" is presented in the following 5 chapters: LITERATURE REVIEWOverview of Silkworm

Ngày tải lên: 20/12/2024, 14:58

... atoms: Ct of the C-terminus, Cc of Asp and Cd of Glu, and Og of Tyr Positive unit charges were added at the following atoms: Nt of the N-terminus, Nf of Lys, Cf of Arg, and Nd or Ne of His (depending ... regulation of protein–protein interactions as a result of changes in phosphorylation state of the regulatory subunit Although recent studies have addressed the hydrophobic character of packing of RIIa ... II of monomer 1, and helices I¢ and II¢ of monomer 2, are intertwined We call this a top-bottom structure The inset of Fig shows a cylinder model of the lowest total energy structures of each of

Ngày tải lên: 08/03/2014, 22:20

... (TTR)-related proteins comprise a protein family of 5-hydroxyiso-urate hydrolases with structural similarity to TTR In this study, we tested the amyloidogenic properties, if any, of sea bream ... packing of the protein core [41–43], increased electrostatic inter-actions on the surface of the protein [44,45], more pro-lines and alanines [46,47], and increased hydrogen bonding of the polypeptide ... frequently used to induce and monitor the degree of protein aggregation and fibril formation of hTTR [28,53] Application of this method to the three proteins in our study showed that hTTR displayed

Ngày tải lên: 16/03/2014, 01:20

... sequences of each protein The chimeric protein composed of the N-ter-minal domain of hoPL and of the C-terN-ter-minal domain of hoPLRP2 was named NcC2 Conversely, the other chimeric protein, bearing ... The properties of the chimeras were compared to those of the original proteins bearing the modifications induced by the con-structions in the chimeric proteins and compared with the properties of ... activity or the behavior of the proteins Kinetic properties of chimeric proteins) effects of bile salts and colipase The lipolytic activity of the different chimeric proteins was investigated by

Ngày tải lên: 16/03/2014, 06:20

... 1RNA-binding properties of HCF152, an Arabidopsis PPR proteininvolved in the processing of chloroplast RNA Takahiro Nakamura1, Karin Meierhoff2, Peter Westhoff2and Gadi Schuster1 1 Department of Biology, ... the possible protein–protein interactions of HCF152, we produced the protein and several truncated versions in bacteria, and analyzed its protein–protein interactions and RNA-binding properties ... lgÆmL)1of yeast tRNA (Sigma) for 15 min The protein and RNA were crosslinked by 1.8 J of UV irradiation in a UV-crosslinker (Hoefer Inc.) following digestion of the RNA by 10 lg of RNaseA and 30 U of

Ngày tải lên: 17/03/2014, 10:20

... intensities of the band of intact protein at the beginning of tryp-sinolysis and at the fixed time of tryptryp-sinolysis) against the time of incubation (Fig 8D) The apparent rate constants of trypsinolysis ... model protein substrates Reduction of the disulfide bonds of insulin results in dissociation of its peptide chains and aggregation of chain B Addi-tion of the wild-type HSP22 retarded the onset of ... eliminates one poten-tial site of chemical modification, the probability of crosslinking of the K137E mutant by DMS is higher than the probability of crosslinking of the wild-type protein This fact agrees

Ngày tải lên: 23/03/2014, 07:20

... investi-gation of the chemical modifications of OBP as a result of incubation with large excesses of HNE and evaluation of their effects on the binding properties of the protein; (c) determination of OBP ... Evaluation of the third hypothesis, the molecular basis of which is described above, is the aim of this study Here, we report the binding properties, chemical modification and chemical resistance of recombinant ... Evaluation of the protective role of OBP against HNE cytotoxicity in a simplified model simulating the nasal epithelium The aim of this experiment was a preliminary evalua-tion of the protective role of

Ngày tải lên: 23/03/2014, 10:20

... relevance Analysis of the properties of this region illuminated a unified mechanism for the formation of the peptide bond, the translocation of the tRNA molecules and the entrance of nascent proteins into ... various binding modes of those analogs is identical to that of ASM [8], and analyses of these modes indicate that the chemical nature of each analog may dictate the properties of its binding mode ... the environment of the derived ASM-P-site 3¢ end is similar to that of ASM Furthermore, the derived P-site 3¢ end of the tRNA mimic is positioned in a manner consistent with most of the available

Ngày tải lên: 23/03/2014, 17:22

... Modification of virus envelope proteins often results in the loss of infection as envelope proteins are required for spread of infection In the baculovirus AcMNPV, the envelope glycoprotein gp64 ... target protein as a N-terminal fusion to a second copy of gp64 [37– 39] Boublik et al [37] suggested that incorporation of the target protein was a result of co-oligomerization of the gp64 fusion proteins ... avidity display of short peptides on the surface of virions and infected cells [23] To gain further insight into the structural properties of gp64 and to increase the accessibility of peptide insertions

Ngày tải lên: 23/03/2014, 21:21

... sequence of branch points of plants (YTNAN) upstream of the 3¢ splice site [24] We next analyzed the promoter region of GmPDIM, 2340 bp upstream of the translational initiation codon ATG A search of ... (supplementary Fig S4) Nucleotide sequence of the ORF of the GmPDIM gene was identical to that of the cDNA Comparison of the soybean genomic sequence of GmPDIM with those of A thaliana (AGI number At1g04980 ... required for shedding of the soluble major his-tocompatibility complex class I-related ligand, resulting in the promotion of tumor immune evasion [10] In plants, a set of 22 orthologs of known PDI-like

Ngày tải lên: 30/03/2014, 04:20

... higher affinity for ACTH-derived peptides than a-, b-, and c-MSH Our unpublished results on characterization of the chicken MCRs suggest similar preference to ACTH-derived peptides Our new results ... fluorescence protein (EGFP) fusion to show the presence of SacMC3R in plasma membrane of Chinese hamster ovary and HEK293 cells but the SacMC5R was retained in intracellular compart-ments of these ... Expression of MC1R is also detected in other skin cell types and in a number of peripheral tissues, including leukocytes, where it mediates the broad anti-inflammatory actions of the melanocortin peptides

Ngày tải lên: 30/03/2014, 15:20

... formation of amyloid precipitates and therefore that lim-ited proteolysis of proteins can be a causative mechanism of protein aggregation and fibrillogenesis Indeed, a vast majority of protein deposits ... of proteins can be induced to aggregate into highly ordered protein aggre-gates [1–10] Considering that all protein fibrils, inde-pendently of the native structure of the given amyloidogenic protein, ... tumor cells of a partly folded variant of LA bound to oleic acid [35,36], the ability of the protein to bind histones [37,38] and the bactericidal activity of some of its chymotryptic peptides [39]

Ngày tải lên: 30/03/2014, 16:20

... them with sequences of cationic peptides in the venom of other arthropods EXPERIMENTAL PROCEDURES Collection of venom Venom of O carinatus was collected by electrical stimulation of the telson with ... Determination of synergism of cationic peptides with conventional antibiotics Twofold serial dilutions of amoxicillin, levofloxacin, cefuroxime and erythromycin were tested in the presence of a constant ... activity of the peptides was assayed by microspectrophotometry of liquid cultures grown in microtiter plates as described previously [33] Briefly, in one well of a 96-well microplate, 20 lL of the protein...

Ngày tải lên: 21/02/2014, 15:20

... mixture of 10 mL taken from each of the five reaction mixtures The method consists of adding various iodoacetamide and iodoacetate ratios to portions of the protein to generate a complete spectrum of ... or presence of ATP, show that ATP has little or no effect on this activity Interestingly, comparison of the genomes of archaea and bacteria showed the existence of a group of redox proteins with ... Assessment of the ATP binding properties of Hsp90 J Biol Chem 271, 10035–10041 35 Quemeneur, E., Guthapfel, R & Gueguen, P (1994) A major phosphoprotein of the endoplasmic reticulum is protein disulfide...

Ngày tải lên: 16/03/2014, 16:20

... Study the effects of crystallinity on the physical properties of the PEAs  Prepare a PEA with an ester to amide ratio of 4:1 in order to model the trend observed in the physical properties versus ... structure resulted in a decrease of thermal stability a The increase of ester to amide ratio did not impact dramatically the thermal degradation of the PEAs b The increase of ester to amide ratio decreased ... biodegradability of PEAs with varying ratios of ester to amide groups  Increase the molecular weights of the synthesized PEAs to further improve the thermal and mechanical properties (such as...

Ngày tải lên: 02/07/2014, 13:01

... the absence of infiltration of immunocompetent cells and tissue destruction (Fig 1d) Histological examination of joint sections of AMD3100-treated mice that did show clinical symptoms of arthritis ... Table Inhibition of the incidence and mean score of CIA by treatment with AMD3100 Experiment number Treatmenta Cumulative incidence (%) Start of treatmentb End of treatmentc Score of arthritis (mean ... of the pits was performed at a magnification of ×20 in 15 areas of constant size, positioned adjacent to one another and spanning the whole quartz slide In all slides, the minimum threshold of...

Ngày tải lên: 09/08/2014, 07:20

... Mathison et al.: Salivary gland derived peptides as a new class of anti-inflammatory agents: review of preclinical pharmacology of C-terminal peptides of SMR1 protein Journal of Inflammation 2010 7:49 ... Journal of Inflammation 2010, 7:49 http://www.journal-inflammation.com/content/7/1/49 Page of 11 Intravenous injection of feG 20 minutes before LPS dose-dependently reduced the length of time of disruption ... within a window of concentrations of about 0.0035 to 0.35 ng/mL, and that in model studies in rats feG dosage of 100 μg/kg was consistently found to be effective regardless of route of administration,...

Ngày tải lên: 11/08/2014, 03:20