annotating and recognising named entities in clinical notes

... obtain opinions from MOIT and the ministry managing the specialized industry [line ministry] in the following cases: (a) It shall obtain an opinion from MOIT and from the line ministry on issuing ... to other wholesaling and retailing business entities and other organizations; and does not include the activity of retailing 7 Retailing means the activity of selling goods to individuals, family ... CHAPTER 4 17 Reporting Regime, Sending and Archiving Licences, and Information Disclosure 17 Article 40 Reporting regime 17 Article 41 Sending and archiving licences, and information disclosure

Ngày tải lên: 19/02/2018, 10:01

... reported in ta-ble 1 and 2 This set of named entities has been defined in order to provide more fine semantic in-formation for entities found in the data, e.g a person is better specified by first and ... entity terminals (as they are pre-terminals nodes in the trees) The other entities, like pers.ind or amount, are called entities or non-terminal entities, depending on the context Entities Since the ... discussed in the introduction and in section 2, since CRFs and models for parsing constitute the main issue in our work, we discuss some important models here Beyond the models for parsing discussed in

Ngày tải lên: 24/03/2014, 03:20

... AccessThymoglobulin, interferon-g and interleukin-2 efficiently expand cytokine-induced killer (CIK) cells in clinical-grade cultures Giuseppina Bonanno1,2, Paola Iudicone2, Andrea Mariotti1, ... T cells and NK cells, insofar they express CD3 and are rapidly expandable in culture like T cells, while not necessitating functional priming for in vivo activity like NK cells Interestingly, ... permeabilized and labeled as detailed in Materials and Methods The percentage of cells staining positively for intracellular FoxP3 is indicated both at baseline and after 21 days in culture Quadrant

Ngày tải lên: 18/06/2014, 16:20

... research, and choosing study instruments These findings have implications for clinicians, for QOL researchers, and for investigators choosing an instrument Clinicians may expect measured QOL (and, ... screening value was 16 or higher The last 6 instruments were not used in the screening population. The information in Appendix Table 1 should be useful to others in planning future studies of clinically ... performance of the var-ious instruments in a cohort of persons who were initially clinically depressed, to determine which instruments showed the most change, and to provide some informa-tion about the

Ngày tải lên: 20/06/2014, 15:20

... Tolerability and adverse events in clinical trials of celecoxib in osteoarthritis and rheumatoid arthritis: systematic review and meta-analysis of information from company clinical trial reports R Andrew ... quality using a three-item, 1- to 5-point scale [12], and at least two points, one each for randomisation and dou-ble blinding, were required for inclusion Trials were scored for validity using an ... event, and patients with any serious adverse event For gastrointestinal adverse events, we included an overallmeasure of gastrointestinal tolerability as well as individualgastrointestinal adverse

Ngày tải lên: 09/08/2014, 06:22

... Erosion and joint space narrowing scores of MCP and PIP joints at inclusion and follow-up Erosion and joint space narrowing scores of MCP and PIP joints at Inclusion and follow-up Erosion and joint ... scores in anti-CCP-negative RA patients Correlations between joint swelling and the erosion score and between joint swelling and the joint space narrow-ing score were determined for each MCP and ... inclusion and follow-p Swelling of the MCP and PIP joints at inclusion and follow-up Joint swelling (mean and 95% confidence interval [CI]) of the metacarpophalangeal (MCP) and proximal interphalangeal

Ngày tải lên: 09/08/2014, 06:23

... disease and treatment and revealed an initial increase in BUN and creatinine and decrease in phosphorus, which coincided with ART initiation (Figure 2) These values tended to normalize following ... post infection 0 1 2 3 PMPA 30mg/kg PMPA 20mg/kg B. Figure 2 Longitudinal changes in serum BUN, creatinine and phosphorus following SIV infection and ART treatment. Longitudinal changes in Blood ... light microscopic level and normal BUN and creatinine levels in serum, reinforcing the relative insensitivity of these tests in diagnosing renal pathology For these rea-sons, investigators should

Ngày tải lên: 10/08/2014, 05:21

... lineages such as intestine [52] and from the ectodermal tissues including skin [53], deciduous teeth [54] and nerve tissue [8,9,55,56] ASCs originate during ontogen-esis and remain in a marginal ... located in blood, liver, BM, lung, kidney and pancreas, endothelial ones found in BM and placenta, epithelial ones located in liver and pancreas and neural ones located in brain and spinal cord ... Interestbusulphan-contain-ing results have been obtained in VOD treatment by oral defibrotide [105] and combination of intravenous heparin, oral glu-tamine and ursodiol [106]. Obstacles and possible solutions

Ngày tải lên: 10/08/2014, 10:20

... external funding and the difference between total external and internal (in-kind) funding will be tracked Table 2: NCCCP site deliverables and evaluation metrics Clinical Trials Increase clinical trial ... research and in clinical care Federal research institutions are scrutinized and criticized for the limited existing initiatives that facilitate a rapid transla-tion of research findings into clinical ... growing commitment to reconfiguring clinical research and the need to improve access to state-of-the-art cancer care in community settings Reconfiguring clinical research In 2002, the National Institutes

Ngày tải lên: 11/08/2014, 05:21

... positive impacts on process included: believing that involving patients in decision-making promotes trust and honesty and, in turn, leads to better diagnosis and care[51]; helping patients address all ... analytic approach, "beginning with a basic set of codes based on a priori theoretical understanding and expanding on these codes by readings of the text"[26] The beginning set of a priori codes ... citation purposes) decision making[63] Therefore, in order to not increase inequity in health (patients who are not invited to be involved in decision making regarding their health, but who want

Ngày tải lên: 11/08/2014, 05:22

... causing inhibition of degradation of collagen andcausing its accumulation thereby causing OSMF The rise in serum copper may be due to increased turn over of cer-uloplasmin in the serum of carcinoma ... stress and lipid peroxidation [38] Iron is also required for collagen synthesis by enzymes in hydroxylation of proline and lysine This hydroxylation of proline and lysine is cata-lyzed by proline ... peroxidase, type I iodothyronine deiodinase, metal-loprotein, fatty acid binding protein and selenoprotein P therefore selenium is considered as an antioxidant nutri-ent and the diseases where low

Ngày tải lên: 11/08/2014, 23:22

... correlations of SOC, BDI, BAI and SDQ-em scores in measurement 1 of the non-clinical sample (NC1), measurement 2 of the non clinical sample (NC2) (6 months interval) - and in the clinical sample (C). ... non-clinical and clinical samples The SOC scale and measures of anxiety and depression showed similar pat-terns of correlations to health-related parameters in both non-clinical and clinical samples ... BDI in the non-clinical sample on both mea-surements and also in the clinical sample (table 2) Trang 5Multiple regression models showed that BDI was thestrongest predictor of SOC in the non-clinical

Ngày tải lên: 12/08/2014, 01:21

... The binding of LPS via LBP and CD14 to TLR enhances mitogen activated pro-tein kinase (MAPK) signalling and promotes the secre-tion of pro-inflammatory cytokines and chemokines [6] CD14 can bind ... detection of inflammatory and infective lung dis-eases in childhood are of high interest Lipopolysaccharide (LPS) is recognized by the human immune system via binding to LPS binding protein (LBP) and ... treatment resulted in increased mCD14 expression on monocytes [21] and alveolar macrophages [34] Our findings indicate that 40 h incubation with LPS and CpG induced sCD14 secretion and increased mCD14

Ngày tải lên: 12/08/2014, 11:21

... Open AccessDiagnostic value and clinical laboratory associations of antibodies against recombinant ribosomal P0, P1 and P2 proteins and their native heterocomplex in a Caucasian cohort with systemic ... determine the diagnostic value and clinical laboratory associations of autoantibodies against recombinant ribosomal P0, P1 and P2 proteins and their native heterocomplex in systemic lupus erythematosus ... recombinant ribosomal protein P0, P1 or P2 expressed in insect cells (DIA-RECT, Freiburg, Germany) Sera diluted 1:201 in phos-phate-buffered saline (PBS) and 0.1% (wt/vol) casein were added and

Ngày tải lên: 12/08/2014, 15:22

... reported worsening outcome after discontinuing routine use of albumin to induce hypervolemia in SAH [80] Lumbar drainage of CSF and intracisternal thrombolysis The amount of blood in the subarachnoid ... simvastatin in a smaller group of patients [140] The incidence of TCD-defined vasospasm and DID was signifi-cantly reduced in the simvastatin group The routine use of statins in SAH is awaiting larger, ... vaso-spasm is increased in the presence of systemic inflammatory response syndrome [27] Furthermore, cerebrospinal fluid (CSF) levels of interleukin-1β and -6 in patients with SAH are increased during

Ngày tải lên: 13/08/2014, 03:21

... basal insulin Monotherapy: Meglitinide, SU, AGI, metformin, TZD, pre-mixed insulin analogs or basal insulin Monotherapy or combination therapy Pre-mixed insulin analogs Pre-mixed insulin analogs, ... Glargine vs NPH Insulin Added to OralsRiddle MC et al and the Insulin Glargine 4002 Study Investigators Diabetes Care 2003:26:3080-3086 Trang 42Insulin Glargine vs NPH Insulin Added to Oral ... 1Glycemic Targets in Clinical Practice: Postprandial vs Preprandial and Fasting? Steven D Wittlin MD University of Rochester School of Medicine and Dentistry Rochester, New York Trang 2In all affairs

Ngày tải lên: 13/08/2014, 09:38

... adhesion involves the interaction of leukocyte integrins of the beta 2 subfamily (CD11a, CD11b and CD11c) with endothelial ligand receptors [19] An increase in the expression of those integrins on ... these integrins on neutrophils is clearly induced ex vivo upon LPS stimulation [38] In a clinical setting, Russwurm et al [20] found increased CD11b expression in patients with sepsis and septic ... pathogenesis of sepsis involves a complex interactionbetween host and infecting microorganism, including bacterial recognition, cell activation and transmigration, phagocytosis and destruction of

Ngày tải lên: 13/08/2014, 10:20

... something special" or "I think I will be something like a guinea pig": information and assent of legal minors in clinical trials – assessment of understanding, appreciation and reasoning ... providing information about clinical tri-als according to informed consent criteria and the under-standing of information related to clinical trials The appreciation of children and adolescents and ... information about clinical trials and assessed understanding, appreciation and reasoning We adapted this tool for legal minors and examined 19 children and adolescents between the ages of 7 and

Ngày tải lên: 13/08/2014, 18:21

... considerable clinical importance, especially in scenarios with diminished to absent shivering or inadequate passive warming In a sustained cold outdoor environment, such as in prolonged ... warming or passive warming with the addition of active warming by opening of sequentially numbered and sealed envelopes containing randomized study protocols. A tympanic sensor was placed in ... 2 cm), reaching about 50 °C within 2 minutes, was applied across the anterior upper torso, leaving only one layer of thin clothing between the heat pad and the skin. If the clothing had to be

Ngày tải lên: 13/08/2014, 23:20

... expressed at considerably lower levels in both the mixed gastric and intestinal-type and solely intestinal-intestinal-type of gastric cancers (Li et al., 2004) Interestingly, poorly differentiated or ... MLH1 and MSH2 protein are essential in the mismatch repair machinery and mutations in MLH1 and MSH2 have been implicated in HNPCC (Boland et al., 1998) Many colorectal cancers with an intact ... inhibiting TYMS that causes depletion of thymidines and disruption DNA and RNA synthesis As a result, the cell undergoes apoptosis by “thymineless” death Interestingly, part of the interest in

Ngày tải lên: 03/10/2015, 20:57