and the risk of oral cancer

Silica and asbestos exposure at work and the risk of bladder cancer in Canadian men: A population-based case-control study

Silica and asbestos exposure at work and the risk of bladder cancer in Canadian men: A population-based case-control study

... Department of Health and Human Services based on unequivocal epidemiologic evidence for lung cancer and mesothelioma [8, 9] However, the impact of these expo-sures on the risk of cancer at other sites ... accounting for almost 90% of all bladder cancers [13] Smoking is the most important risk factor for bladder cancer based on an attributable risk of 50% [14] Other established risk factors include ... silica and asbestos exposure by periods of 20 and 40 years Results The number of workers exposed and the most common exposure coding (concentration, frequency and reliabil-ity) among the 2014

Ngày tải lên: 17/06/2020, 03:18

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Association between alcohol intake and the risk of pancreatic cancer: A dose response meta-analysis of cohort studies

Association between alcohol intake and the risk of pancreatic cancer: A dose response meta-analysis of cohort studies

... BMI, and EI influenced the association between alcohol intake and the risk of pancreatic cancer However, we could not determine the effects of these potential confounding factors on the risk of ... consumption and risk of pancreatic cancer in the Netherlands Cohort Study Am J Epidemiol 2009;169:1233 –42. 35 Jiao L, Silverman DT, Schairer C, et al Alcohol use and risk of pancreatic cancer: the NIH-AARP ... from the Japan collaborative cohort study for evaluation of cancer risk In J Cancer 2002;99:742 –6. 11 Michaud DS, Giovannucci E, Willett WC, et al Coffee and alcohol consumption and the risk of

Ngày tải lên: 21/09/2020, 09:24

11 13 0
Dietary calcium intake and the risk of colorectal cancer: A case control study

Dietary calcium intake and the risk of colorectal cancer: A case control study

... [33], and the presence of ionized calcium may inhibit the toxic and potential ir-ritating effects of fatty acids and free bile acid in the colon [34] The sub-sites of the colon (proximal and distal) ... 1 shows the relationship between daily dietary calcium intake and the risk of colorectal cancer in men and women Figure 2 shows the relationship between dietary calcium intake and risk of colorectal ... colorectal cancer risk and meta-analysis of randomized controlled trials (RCTs) did not show statistically significant effects of calcium supplementation on colorectal cancer risk [8, 9] Therefore the

Ngày tải lên: 22/09/2020, 23:00

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Coffee consumption and the risk of gastric cancer: A meta-analysis of prospective cohort studies

Coffee consumption and the risk of gastric cancer: A meta-analysis of prospective cohort studies

... to investigate the association between coffee consump-tion and the risk of gastric cancer and quantify the dose–response relationship of coffee consumption with gastric cancer risk Methods Search ... consumption and the risk of gastric cancer Figure 2 showed the results from the random-effects meta-analysis combining the RRs for gastric cancer in Fig 1 Flow chart showing the relevant studies of coffee ... analysis of coffee consumption with the risk of gastric cancer Nine studies with 14 reports were included in the dose–re-sponse analysis of coffee consumption and gastric cancer risk The pooled

Ngày tải lên: 22/09/2020, 23:57

14 24 0
Consumption of hot beverages and foods and the risk of esophageal cancer: A meta-analysis of observational studies

Consumption of hot beverages and foods and the risk of esophageal cancer: A meta-analysis of observational studies

... consumption and the risk of esophageal cancer The results from the random-effects meta-analysis of hot beverage and food consumption and the risk of EC were shown in Figure 2 Thirty-two of 47 independent ... were to examine the stability of the primary re-sults and explore the resources of potential heterogen-eity The associations between hot beverage and food consumption and the risk of EC were similarly ... beverages and foods and EC risk [11-13], arguing that the oral cavity could modulate the heat, and the temperature could fall too rapidly to cause injury to the esophageal mucosa [14] But many other

Ngày tải lên: 30/09/2020, 11:14

13 15 0
Genetic variation in TLR or NFkappaB pathways and the risk of breast cancer: A case-control study

Genetic variation in TLR or NFkappaB pathways and the risk of breast cancer: A case-control study

... candidate gene studies have reported on genetic variants in TANK af-fecting the risk of breast cancer In the CGEMS GWAS data, neither of these SNPs was strongly associated with breast cancer risk ... increased risk of breast cancer (OR 1.15, 95% CI 1.01–1.30) Although the associations with breast cancer were of similar magnitude and direction for most SNPs when comparing the two datasets, the risk ... with ductal and luminal subtypes respectively (Table 3) For most SNPs, the magnitude of risk associated with each subtype was the same as with the overall risk of breast cancer Fur-ther, onlyTLR9

Ngày tải lên: 05/11/2020, 06:22

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Oral primary care: An analysis of its impact on the incidence and mortality rates of oral cancer

Oral primary care: An analysis of its impact on the incidence and mortality rates of oral cancer

... was because of the nature of the data collected and to ensure the legitimacy of the data collected In the case of the oral health instrument, the primary respondent was the dentist The third survey ... far and the lack of long-term and population-based studies, the aim of this study was to analyze the effect of the parameters re-lated to the PHC structure and work process on the in-cidence and ... outlines the results of the multivariable analysis Discussion Main findings Our findings highlighted the association of oral cancer mortality rates and the oral primary care The exam of a time

Ngày tải lên: 06/08/2020, 04:30

11 31 0
Chronic kidney disease and the risk of cancer: An individual patient data meta-analysis of 32,057 participants from six prospective studies

Chronic kidney disease and the risk of cancer: An individual patient data meta-analysis of 32,057 participants from six prospective studies

... the effects of reduced kidney function and risk of cancer and cancer death The availability of individual data allowed for an assessment of the potential influence on estimates of competing risks ... Assessment of incident cancers and cancer deaths Incident cancers were defined as the first cancer diag-nosed after inception of the individual studies Diagno-ses of incident cancers and cancer ... writing of the manuscript CB supervised the statistical analyses and contributed to the writing of the manuscript JCC conceived of and designed the study and contributed to the writing of the manuscript

Ngày tải lên: 20/09/2020, 14:14

11 13 0
STAT3 polymorphism and Helicobacter pylori CagA strains with higher number of EPIYA-C segments independently increase the risk of gastric cancer

STAT3 polymorphism and Helicobacter pylori CagA strains with higher number of EPIYA-C segments independently increase the risk of gastric cancer

... evaluate the number of EPIYA-C segments as a predictor of gastric cancer as well as the co-participation of the bacterial EPIYA-C segments and STAT3 polymorphism in the risk of the disease The logistic ... nuclei in the gastric stroma cells and glandular cells of a carrier of AA genotype and e and f, densely stained nuclei of 100 % of cells, both of the gastric stroma (arrow head) and glands (arrow) ... localization of p-STAT3 in the antral glandular cells and stroma cells of carriers of AA and GG STAT3 rs744166 genotypes The percentage of p-STAT3 expression was significantly higher in the nuclei of the

Ngày tải lên: 28/09/2020, 10:07

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Interplay between 3′-UTR polymorphisms in the vascular endothelial growth factor (VEGF) gene and metabolic syndrome in determining the risk of colorectal cancer in Koreans

Interplay between 3′-UTR polymorphisms in the vascular endothelial growth factor (VEGF) gene and metabolic syndrome in determining the risk of colorectal cancer in Koreans

... Colorectal cancer (CRC) is the third most common type of cancer and the second leading cause of cancer-related mortality in Western countries [1] The prognosis of pa-tients with CRC depends on the tumor ... laboratory and others [6,24] The other three single nucleotide polymor-phisms (SNPs) in the VEGF 3′-UTR, 1451C > T, 1612G > A, and 1725G > A, are poorly understood in the context of their ... susceptibility The purpose of this study was to investigate whether these poly-morphisms ofVEGF 3′-UTR correlate with CRC suscepti-bility and the genetic contributions are modified by the presence of MetS

Ngày tải lên: 14/10/2020, 13:10

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Alcohol consumption, cigarette smoking and the risk of subtypes of head-neck cancer: Results from the Netherlands Cohort Study

Alcohol consumption, cigarette smoking and the risk of subtypes of head-neck cancer: Results from the Netherlands Cohort Study

... smoking and the risk of subtypes of head-neck cancer: results from the Netherlands Cohort Study Denise HE Maasland1*, Piet A van den Brandt1, Bernd Kremer2, R Alexandra (Sandra) Goldbohm3 and Leo ... habits, and other cancer risk factors Figure 1 Flow diagram of the number of subcohort members and cases on whom the analyses were based *PALGA: nationwide network and registry of histopathology and ... consumption and risk of subtypes of head-neck cancer; Netherlands CohortStudy (NLCS), 1986– 2003 Categorical median Person time at risk (years) No of cases RR (95% CI) No of cases RR (95% CI) No of cases

Ngày tải lên: 05/11/2020, 00:46

14 18 0
Prognostic value of stromal and epithelial periostin expression in human prostate cancer: Correlation with clinical pathological features and the risk of biochemical relapse or

Prognostic value of stromal and epithelial periostin expression in human prostate cancer: Correlation with clinical pathological features and the risk of biochemical relapse or

... survival was calculated as the amount of time between the date of prostatectomy and the date of death, regardless of the cause Table 2 POSTN expression in epithelium or stroma of tumor or normal tissue ... predict the risk of PSA failure, regard-less of which Gleason score variable was used By contrast, stromal IRS was the only independent predictor of the risk of death, regardless of how the Gleason ... not possible, by contacting the local tumor registry or the registry office of the patient’s place of residence The main characteristics of the patients making up the study cohort are summarized

Ngày tải lên: 05/11/2020, 08:13

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Longitudinal associations between BMI change and the risks of colorectal cancer incidence, cancer-relate and all-cause mortality among 81,388 older adults

Longitudinal associations between BMI change and the risks of colorectal cancer incidence, cancer-relate and all-cause mortality among 81,388 older adults

... between BMI change and the risks of colorectal cancer incidence, cancer-relate and all-cause mortality among 81,388 older adults BMI change and the risks of colorectal cancer incidence and mortality ... (BMI) and the risks of colorectal cancer (CRC) incidence, cancer-related and all-cause mortality among midlife to elder population Methods: A total of 81,388 participants who were free of cancer and ... increase in weight and the risk of incident CRC [16] Similarly, investigations on weight loss are challenging, as studies of its impact on the risk of cancer and mortal-ity are sparse and provided

Ngày tải lên: 17/06/2020, 19:13

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Honokiol inhibits sphere formation and xenograft growth of oral cancer side population cells accompanied with JAK/ STAT signaling pathway suppression and apoptosis induction

Honokiol inhibits sphere formation and xenograft growth of oral cancer side population cells accompanied with JAK/ STAT signaling pathway suppression and apoptosis induction

... densitometric values indicated at the top of the bands are expressed relative to the value of parental cells after being normalized to actin (#: The intensity of ABCG2 band of parental SAS cells was ... thousand times higher) than the non-SP Therefore, we used SAS SP xenograft as a model to evaluate the effectiveness of honokiol The effects of honokiol on the increase of Bax to Bcl-2 ratio and ... to 70 and 38 % by honokiol at dose of 5 and 10 μM, respectively In SAS sphere cells, the number of colonies was even down to 50 and 22 % by the same doses of honokiol (Fig 4a) After 48 h of honokiol

Ngày tải lên: 21/09/2020, 09:33

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A functional genetic variant in fragile-site gene FATS modulates the risk of breast cancer in triparous women

A functional genetic variant in fragile-site gene FATS modulates the risk of breast cancer in triparous women

... FFS, JZ and LQ performed the experiments and statistical analysis, participated in the design of the study, and drafted the first version of the manuscript YWZ and PX participated in the acquisition ... acquisition of data, helped in the interpretation of the results and to draft the manuscript JCL, KXC and ZL conceived the study and supervised its design and coordination, and critically revised the ... However, whether the non-proteolytic ubiquitination of p53 by FATS may have some physiologic significance and whether the genetic variants of FATS may modulate the risk of breast cancer remain

Ngày tải lên: 28/09/2020, 01:25

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Association between epidermal growth factor gene +61A/G polymorphism and the risk of hepatocellular carcinoma: A meta-analysis based on 16 studies

Association between epidermal growth factor gene +61A/G polymorphism and the risk of hepatocellular carcinoma: A meta-analysis based on 16 studies

... indicates the OR and the ends of the diamond correspond to the 95% CI. Trang 9partly ascribed to the higher prevalence of EGF +61G allele.The frequency of EGF +61G among the controls of all studies ... ◆) and a horizontal line The size of a box (gray square) is proportional to the weight that the study has in calculating the summary effect estimate (`) The center of the diamond indicates the ... because of obvious irrelevance to our study aim by browsing the titles and abstracts According to the in-clusion criteria, 32 of the remaining 45 records were fur-ther excluded by review of the full

Ngày tải lên: 29/09/2020, 16:09

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Factors infl uencing the risk of breast cancer – established and emerging ppt

Factors infl uencing the risk of breast cancer – established and emerging ppt

... views of the funders and the EU institutions Factors influencing the risk of breast cancer – established and emerging April 2008 Introduction Most of us will know of someone affected by breast cancer, ... However, all the established risk factors together can only explain about half of breast cancer cases and for the remainder, scientists and doctors are still unsure of the causes2,3 One of the suggested ... the ovaries) and is essential for the development of the breast, paradoxically oestrogen is also involved in the development of breast cancer via the stimulation and proliferation of breast cancer...

Ngày tải lên: 15/03/2014, 01:20

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Critical evaluation of diagnostic aids for the detection of oral cancer docx

Critical evaluation of diagnostic aids for the detection of oral cancer docx

... in the detection of oral cancer and precancer J Oral Pathol Med 1996;25(3):97–103 53 Onofre MA, Sposto MR, Navarro CM Reliability of toluidine blue application in the detection of oral epithelial ... D, Frist S The relevance of the high positive predictive value of the oral brush biopsy Oral Oncol 2005;41(7):753–5 42 Sciubba JJ Improving detection of precancerous and cancerous oral lesions ... disease of interest (in this case: oral dysplasia and/ or oral cancer) and other noncancerous conditions? The importance of this criterion can be appreciated by recalling the development of carcinoembryonic...

Ngày tải lên: 06/03/2014, 02:21

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Work-Related Health Limitations, Education, and the Risk of Marital Disruption pdf

Work-Related Health Limitations, Education, and the Risk of Marital Disruption pdf

... in the amount of work they could perform, irrespective of whether they are limited in the kind of work they can perform (1 = yes, and = no) The vast majority of respondents who noted that they ... indicated whether the husband made less than 40% of the couple’s total income, and the second dummy variable indicated whether the husband made more than 60% of the couples’ total income The omitted ... by the end of the study but were at risk of divorce until the study ended) The model I estimated is of the following general form and takes into account the fact that all eligible members of...

Ngày tải lên: 28/03/2014, 21:20

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Reducing the Risk of Breast Cancer With Medicine: A Guide for Women potx

Reducing the Risk of Breast Cancer With Medicine: A Guide for Women potx

... breast cancer Risk of Breast Cancer Most women will never get breast cancer A woman’s risk of breast cancer depends on her age and other risk factors Most women who get breast cancer have no risk ... others Talk with your doctor or nurse about your risk of breast cancer Tamoxifen and raloxifene can lower the risk of getting some kinds of breast cancer These medicines also can raise the risk ... Blood clots in the lungs and legs Tamoxifen and raloxifene raise the risk of blood clots Blood clots happen more often with tamoxifen than raloxifene n Endometrial cancer (cancer of the uterus lining)...

Ngày tải lên: 29/03/2014, 01:20

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