and overall survival in critically ill patients

... modality in critically ill patients, especially haemodynamically unstable ones Central to its optimal use is an understanding of its clinical effects in critically ill ICU patients Such information ... Synthamin 17 Table 14 Serum amino acid concentration in umol/L Table 15 Daily infusion and losses of individual amino acids Table 16 Clearance of individual amino acids in ml/min Table 17 Changes in ... noted in patients with ARF There was a higher incidence of acute gastrointestinal tract (GIT) bleeding in patients with ARF Such bleeding was in turn associated with greatly increased mortality and...

Ngày tải lên: 16/09/2015, 17:14

... RCTs comparing percutaneous dilatational and surgical tracheostomy in critically ill patients concealment Blinding Intention-to-treat analysis Predefined outcomes Baseline Imbalance ICU, intensive ... reduces the overall incidence of wound infection and may further reduce clinical relevant bleeding and mortality when compared with ST performed in the operating theatre PDT, performed in the ICU, ... critically ill patients to the OT [10] The proportion of patients receiving PDT and ST varies greatly in different practice settings, with ST being performed exclu-sively in some ICUs, PDT being performed...

Ngày tải lên: 12/08/2014, 23:23

... SPRINT is limited to 6 U/hour to minimise saturation and the administration of ineffective insulin [23,29,30,43] Insulin is given predominantly in bolus form for safety, avoiding infusions being ... the practice of using insulin-only protocols In the presence of significant insulin resistance, insulin effect saturates at high concentrations of insulin [23,29,30], limiting the achievable ... cardiovascular patients and SPRINT gastrointestinal patients were randomly eliminated from the patient pools to create the cohorts used for analysis, as shown in Figure 1 The patient elimination pro-cedure...

Ngày tải lên: 13/08/2014, 10:20

... platelets were determined daily for clinical purposes, and aspartate amino transferase, alanine amino transferase, and urate were determined three times weekly using standard clinical laboratory ... frequent in the cardiac patients (P < 0.0001) and least frequent in SAH (2 in AOX and 1 in pla-cebo) The more severe grades of renal failure (increases of 50 μmol/L in 32 patients and of 90 ... = 0.005) as did that of having any infection (P = 0.0015) The lowest infection rate was observed in SAH patients with 13 infections (5 in AOX and 8 in placebo) in 10 patients Length of mechanical...

Ngày tải lên: 13/08/2014, 11:22

... protocols in critically ill patients Introduction Pain, physical discomfort and anxiety are common in critically ill patients The underlying disease, care procedures, pro-longed immobility and sleep ... record the following interventions, defined as events: sedative and analgesic drug bolus, increas-ing or decreasincreas-ing continuous sedation and analgesia, intratra-cheal suctioning, and other potentially ... to sed-ative and opiate drugs and intratracheal suctioning, alone or in combination with drugs, during nurse-driven, protocol-guided sedation and analgesia The interventions were administration...

Ngày tải lên: 13/08/2014, 11:22

... replacement therapy and mortality in critically ill patients with acute kidney injury Sergio Vesconi1*, Dinna N Cruz2*, Roberto Fumagalli3, Detlef Kindgen-Milles4, Gianpaola Monti1, Anibal Marinho5, Filippo ... assessment (SOFA) and serum creatinine at CRRT initiation and CRRT downtime (hours); for IRRT the covariates included were age (10-years increments), sex and RIFLE class at IRRT initiation In addition ... adsorption or combination), timing of initiation and dose of treatment The relationship between patient outcome and treatment dose was first introduced in a landmark study where patients ran-domised...

Ngày tải lên: 13/08/2014, 16:20

... PM: Retinol-binding protein-4 in experimental and clinical metabolic disease Expert Rev Mol Diagn 2008, 8:289-299. 10 Wolf G: Serum retinol-binding protein: a link between obesity, insulin resistance, ... illness and impact the mortality rate, especially in sepsis Retinol binding protein 4 (RBP4) promotes insulin resistance in mice and is systemically elevated in patients with obesity and type ... patients Introduction Hyperglycemia, glucose intolerance and insulin resis-tance are common features of critically ill patients, espe-cially in patients with sepsis or septic shock and even in...

Ngày tải lên: 13/08/2014, 21:21

... EVLWI and CVP using CT scans of the thorax is able to evaluate intravascular and pulmonary fluid status in critically ill patients To obtain representative data in a clinical routine setting, ... Results Patients and patients’ characteristics Thirty critically ill ICU patients were enrolled in this study The patients’ basic demographic data and clinical characteristics including reason ... and EVLWI using standard CT scans of the thorax is not accurate in critically ill patients in a clini-cal setting without the support of quantitative CT ana-lyzing software when compared to invasive...

Ngày tải lên: 13/08/2014, 23:20

... Sixty-seven critically ill adult intensive care patients were divided into two groups, 32 septic critically ill patients (sepsis group) and 35 non-septic critically ill patients (non-sepsis group), in ... proteasome and the percentage of apoptotic lymphocyte median values could be a good indicator of patient prognosis and survival in critically ill patients. Introduction Sepsis in critically ill patients ... prothrombin time, aspartate aminotransferase, alanin e amino transferase, albumin and C-reactive protein, and arterial blood gas analysis were recorded. Routine cultures of urine, blood and suspecte...

Ngày tải lên: 14/08/2014, 07:21

... late initiation of RRT in critically ill patients with AKI is low. • Earlier initiation of RRT in critically ill patients with AKI may have a beneficial impact on survival. • A well-designed randomised ... patient and population characteristics including type of ICU, severity of illness (baseline APACHE II scores), and metabolic derange- ments (baseline creatinine and urea levels). Accordingly, ... will ideally require broad-based consensus on eligibility criteria and operational definitions for ‘early’ and ‘standard’ initiation of RRT in critically ill patients to ensure feasibility and...

Ngày tải lên: 14/08/2014, 07:21

... are invariably associated with improved intracranial tumor control and survival in NSCLC BM patients Keywords: Whole brain radiotherapy, Non-small cell lung cancer, Brain metastases, Overall survival, ... of all NSCLC BM patients newly treated in 2013– 2015 at a single cancer institution in China In this study, patients with WBRT 30–39 and ≥ 40 Gy had esti-mated MTS of OS of 10.3 and 11.9 months, ... between WBRT total dose, intracranial tumor control, and overall survival in NSCLC patients with brain metastases - a single-center retrospective analysis Zhensheng Li* , Dongxing Shen, Jian Zhang,...

Ngày tải lên: 17/06/2020, 19:16

... N-acetylcysteine Sixteen randomized controlled trials investigated the efficacy of NAC in preventing contrast-induced nephropathy, both in patients with pre-existing renal insufficiency and in patients with ... contrast-induced nephropathy included critically ill patients [43] Huber and coworkers investigated whether theophylline reduced the incidence of contrast-induced nephropathy in a prospective study in ... administrations Patients received theophylline intravenously 30 min before infusion of contrast medium Concentrations of serum creatinine and blood urea nitrogen, urine volume, fluid balance, and...

Ngày tải lên: 12/08/2014, 20:21

... epidemiology and incidence of invasive aspergillosis in Table 4 Radiological findings in intensive care unit patients with invasive pulmonary aspergillosis or Aspergillus colonisation Radiological finding ... macrophage killing of Aspergillus spores and mononuclear cell killing of Aspergillus hyphae [40] In the setting of underlying lung disease, there is a risk factor for inva-sive aspergillosis at ... findings in acute invasive pulmonary aspergillo-sis: utility and reliability of halo sign and air-crescent sign for diagnosis and treatment of invasive pulmonary aspergillosis in high-risk patients...

Ngày tải lên: 12/08/2014, 23:21

... as an increase of serum creatinine above the baseline serum creatinine level Acute kidney injury should be both abrupt (within 1–7 days) and sustained (more than 24 hours) When the baseline serum ... kidney injury and maximum RIFLE class F were associated with increased base-line severity of illness and older age (Tables 2 and 3) Patients developing acute kidney injury were slightly older and ... bal-ance in patients with sepsis In Yearbook of Intensive Care and Emergency Medicine 2004 Edited by: Vincent JL Berlin: Springer-Verlag; 2004:58-67 different patterns of inflammatory response in...

Ngày tải lên: 12/08/2014, 23:23

... complications, and their influence on the prognosis in critically ill patients Materials and methods Design This study was designed as a multicenter prospective cohort study of incidence of LD in patients ... Fat infiltra-tion and intrahepatic cholestasis are the typical findings in these patients [28,43,44] The progress of this LD is generally self-limiting but can lead to liver failure in a minority ... participated in its design and coordination, and helped to draft the manuscript TG per-formed the statistical analysis MR and DM were involved in drafting the manuscript or revising it critically...

Ngày tải lên: 13/08/2014, 03:20

... achieved in the 13 remaining patients, which was CIM in six cases, CIP in four, and combined CIM and CIP in three Table 1 Baseline characteristics of the patients Characteristic Age in years ... for the purpose of defining MOF SIRS and sepsis were defined according to current standards [38] Serial clinical and electrophysiological investigations Daily simplified and weekly complete electrophysiological ... com-bined with serial electrophysiological studies may also be val-uable in determining the ultimate prognosis of patients with CRIMYNE and in gauging the rate of recovery, as well as in assessing...

Ngày tải lên: 13/08/2014, 03:20

... gastric emptying variables, (a) t50 and (b) GEC, in critically ill patients The impact of various admission diagnoses on gastric emptying variables, (a) t50 and (b) GEC, in critically ill patients ... nutrition in critically ill patients [1-3] Continuous infusion of liquid nutrient into the stomach is convenient, mini-mally invasive, and cost-effective However, impaired tolerance to gastric feeding ... emptying in ventilated critically ill patients: measurement Key messages • Delayed GE is common in critically ill patients (60%) and is associated with suboptimal delivery of enteral feeds and...

Ngày tải lên: 13/08/2014, 03:20

... were included in this review: 11 stud-ies examining the effects of SAP and 22 studstud-ies on SDD Study and patient characteristics are presented in Tables 2 and 3 for SAP and in Tables 4 and ... increased proportion of included surgical patients Conclusion Antifungal prophylaxis (SAP or SDD) is effective in reducing yeast colonisation and infections across a range of critically ill patients ... urine in surgical patients with infections [2] The development of fungal/yeast infections is a rapidly increasing health problem, especially in hospitalized patients and in patients with impaired...

Ngày tải lên: 13/08/2014, 10:20

... control in critically ill patients, and to inspect the applicability of their definitions Methods We searched in MEDLINE® for all studies evaluating a tight glycaemic control protocol and/or quality ... den, Wouters PJ, Bouillon R, Weekers F, Verwaest C, Schetz M, Vlasselaers D, Ferdinande P, Lauwers P: Outcome benefit of intensive insulin therapy in the critically ill: insulin dose versus glycemic ... with out-come in trauma patients than in other critically ill patients J Trauma 2006, 60:873-879. 42 Krinsley J, Grissler B: Intensive glycemic management in criti-cally ill patients Jt Comm...

Ngày tải lên: 13/08/2014, 11:23

... between CMV and other herpes viruses exists in critically ill patients Trang 6Human herpesviruses -6 and -7HHV-6 infection has been frequently observed in critically ill patients [12,15] In one study, ... seropositive patients developed CMV infection. Table 1 (Continued) Characteristics of studies assessing the rate and outcome of cytomegalovirus infection in critically ill patients Trang 5(median 18%), and ... data for optimizing outcomes in critically ill patients Materials and methods English-language reports of published studies on CMV infec-tion in critically ill immunocompetent patients were identified...

Ngày tải lên: 13/08/2014, 16:20