alpha l iduronidase the development of aldurazyme laronidase

... 7controlled method of localizing biologically active molecules indefined area on the electrodes Also the use of conducting poly-mers in the area of bioanalytical sciences is of great interest since their ... conductive polypyrrole nanowires by the grafting of PPy from isolated synthetic polyelectrolyte molecule Also, the direct electrochemical synthesis of large arrays of uniform and oriented nanowires of ... with self-assembled monolayers of well separated thiolated cyclodextrins in an alkanethiol ‘forest’ (molecular template)[108] A simple strategy for the synthesis of wire/ribbon like polypyrrole nano-structures

Ngày tải lên: 20/03/2014, 13:06

... cooperatives, literally, “Savings and loan associations.”like a lender of last resort Banks that were in trouble could sell bills out of their own portfolio tothe Bank of Prussia The Reichsbank, ... engaged in profit-making activities, includinglending, and especially the discounting of bills Firms whose bills met certain criteria could alwayshave their bills bought and sold by the Bank of Prussia, ... more willing to enter into long-term commitments if they know a lender of last resort will provide liquidity in a general crisis The U.S.had no central bank or other official lender of last resort

Ngày tải lên: 22/03/2014, 20:21

... clinical trials do reveal the analytical validity, clinical validity, and clinical utility of a predictive test, the reliability of test results can still be problematic due to 2 The Clinical ... Debra Leonard of the Weill Cornell Medical College suggested capturing data from the medi-cal practices of early users of predictive tests These data could be used to analyze the clinical value of ... were collected prospectively The assay methods are applied retrospectively after the clinical outcomes of the trial are known Although prospective clinical trials are viewed as the gold standard

Ngày tải lên: 22/03/2014, 20:21

... embroidery tells not only of the riches of available material, but of the habit of personal preparation, instead of the mechanical The little Bible description ofcaptured "needlework alike on ... hollows The butternut in all stages of itsgrowth, from the smallest and greenest to the rusty black of the ripe ones, and the blackest black of the driedshell, was a mine of varied color; and the ... story of embroidery includes in its history all the work of the needle since Eve sewed fig leaves together in the Garden of Eden We are the inheritors of the knowledge and skill of all the daughters

Ngày tải lên: 24/03/2014, 02:20

... levels and were substantiallymore likely to score below the nationally ranked 25th percentile In addition, ELLs aresubstantially less likely than their peers to finish high school About 20% of ... research on the role of English oral proficiency in acquiring English literacy, describe the issues that English-language learners (ELLs)encounter because of their developing English oral proficiency, ... some children in the lowest reading group were relatively orallyproficient in English (after two years of schooling in English), but still couldn’t read well In summarizing the findings, the authors

Ngày tải lên: 24/03/2014, 19:20

... cells, and Itk may regulate the expression of T-bet in these cells, thus regulating iNKT cell development [20] Role of Itk in i NKT cell function Analysis of the remaining Itk-null i NKT cells ... conventional T cells, particularly Th1 cells, IFN-c is predominantly regulated by T-bet, whereas IL-4 is Fig 1 Involvement of Itk in the development of i NKT and NKT-like cd T cells During T-cell development ... section, we discuss the role of Itk in the development of peripheral cd T cells, although Itk also plays a role in the develop-ment of skin cd T cells [38] The cd T-cell population contains many

Ngày tải lên: 28/03/2014, 22:21

... efforts Together with the image of the lotus, the petal in letter "k" brings along a feeling of the consistence in sustainable development and orientation of the bank, creating the image of VPBank ... certain habits of receiving emails, often called the weekly newsletter (Newsletter) The emails which are indiscriminately sent will make customers uncomfortable, and these emails (spam emails) may cause ... procedures The green color shows a fresh vitality with a meaning of bringing sustainable success to customers, as well as success and development of the bank itself Especially, letter "k" at the end of

Ngày tải lên: 23/04/2014, 16:41

... ultimately the world, especially in light of the globalization of financial accounting standards by the International Accounting Standards Board (IASB) The number of organizations and resulting ... represents an integral part of the development of financial accounting standards and the fulfillment of the mission of the FASB Embedded in the second purpose statement is a concept called due process ... letters at the FASB under a methodological process defined by Creswell (1998) Creswell explains that the methodological process or assumption will include detailed descriptions of each case, followed

Ngày tải lên: 01/06/2014, 13:59

... and for clinical-pathological reasons are often divided into two broad categories: small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC) All major histological types of lung cancer ... molecular and cellular functions primarily affected by the E6/E7 coexpression are associated to cellular development, cell cycle, cellular growth and proliferation Interestingly, the analysis of ... http://www.translational-medicine.com/content/9/1/2 Normal Lung Small Cell Lung Cancer Figure Human SCLC hierarchical clustering of the significantly deregulated genes Analysis show human normal control lung

Ngày tải lên: 18/06/2014, 16:20

... inner cell mass of blastocyst Derived from somatic cells Isolated from postnatal adult tissue Allogenic material Autologous or allogenic material Autologous or allogenic material Pluripotent Pluripotent ... and culture of stem cells can change the characteristics of the stem cell due to intra-cellular and extraintra-cellular influences Every cell division has a small chance of introducing deleterious ... for isolation and pre-paration of fetal neural stem cells details of the cells after culture are lacking This anecdotal case report illustrates that the risk of tumour formation of stem cell is

Ngày tải lên: 18/06/2014, 19:20

... Chapel Hill, Chapel Hill, NC, USA, 2 Department of Pediatrics, College of Medicine, Department of Landscape Architecture and Urban Planning, College of Architecture, Texas A&M University College ... Division of General Medicine and Clinical Epidemiology, Cecil G Sheps Center for Health Services Research, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA Email: Debra ... critically for important intellectual content; and have given final approval of the version to be published Acknowledgements We would like to acknowledge the contributions of Jin-Shei Lai PhD,

Ngày tải lên: 18/06/2014, 19:20

... fatigued and stopped the exercise to allow the user to rest The following two examples illustrate the performance of the POMDP model Example 1 assumes that the user is able to reach the maximum target ... paper will present a new controller that was developed based on a POMDP (partially observable Markov decision process), as well as early pilot data collected to show the efficacy of the new system ... This ability to consider the future effects of current actions allows the POMDP to trade off between alternative ways to satisfy a goal and plan for multiple interacting goals It also allows the

Ngày tải lên: 19/06/2014, 08:20

... viên, hợp đồng lao động Quản l l u trữ hồ sơ nhân tài liệu có liên quan Theo dõi thay đổi diễn biến số l ợng lao động Thực thủ tục l hợp đồng lao động toán l ơng chế độ cho người lao động chấm ... tuyển dụng theo quy định Công ty L p kế hoạch quỹ tiền l ơng xây dựng đơn giá tiền l ơng Đăng ký đơn giá tiền l ơng với quan có liên quan L p quản l sổ BHXH, sổ lao động, sổ l ơng theo quy định ... tiền l ơng, nhằm quán triết nguyên tắc trả l ơng theo số l ợng chất l ợng lao động Hay số tiền mà người sử dụng lao động thưởng cho người lao động, điều kiện đặc biệt theo thỏa thuận trước bên theo...

Ngày tải lên: 19/04/2013, 23:00

... well designed policy can help to supply global quality products at global prices Several countries attempted to use targeted policies to enhance industrial development following the example of ... skill premia and thus an acceleration of human capital accumulation (through the complementarity of capital and skilled labour and the substitutability between physical capital and unskilled labour) ... Informal on-thejob training is likely to correlate with the skill content of the job, and hence MNEs offer more of this when they are more skill intensive Little is known about the effects of voluntary...

Ngày tải lên: 23/04/2013, 11:16

... purposes Usually the loan is not large capital needs Therefore, loans are small but the number of loans often plentiful and varied • The client Target customers of consumer lending are individuals and ... recovery, the collateral and customer’s reputation, all of these will affect the interest rate of the bank Besides, the loan time has an effect on the interest rate as well • Furthermore, loans with ... receiving the loan application forms Then, loan documents will be transmitted to the credit department • Step 2: The evaluators will conduct the evaluation of such customer record as collateral, legal...

Ngày tải lên: 25/07/2013, 11:20

... emotionally and politically plausible ideological defense of a level of statism in American politics that previously would have been understood, emotionally and politically, as wholly incompatible ... imagines the long stretch of constitutional development concerning the criminal process provisions of the Bill of Rights as the kernels of later developments, in the process obscuring key developmental ... acts of local school of cials as matters of “state” action and “state” policy The progressive construction of the conduct of local school of cials as “state” policy was supplemented by the further...

Ngày tải lên: 18/02/2014, 11:20

... 'Let the field be joyful, and all that is therein; then shall all the trees of the wood rejoice.' Psalm 96 'Let the floods clap their hands: let the hills be joyful together.' Psalm 98 'The floods ... roof of the forest below The poetic and mythical allusion at the close of the letter falls on the Christian ear like an echo from another and earlier world The Hellenic poets of the Anthology, ... motives as well as religious feeling In the little Octavius of Minucius Felix, a writing full of genuine human feeling of the time of Commodus, the mixture of the heathen culture and opinions of antiquity...

Ngày tải lên: 21/02/2014, 20:20

... In the solution of the transportation problem the people freely used their political institutions Nearly all the numerous canals built after 1825 and several of the early railroads were public ... of the South, and fearful that the fulminations of the abolitionists and the successful efforts of the Northern political leaders to restrict the territorial expansion of slavery only foretold ... Northern States and settled the large unfavorable balance of the Northern foreign trade The multiplication of factories in the North together with the spread of cotton culture in the South and the...

Ngày tải lên: 05/03/2014, 16:20

... series of rational numbers was irrational or transcendental The 1843 publication of their letters prompted Liouville to lay the foundations of the theory of transcendental numbers The detailed table ... the required sankalitam and also the sankalitam of all the sankalitams of all lower powers up to various limits Jyesthadeva’s next lemma stated: Multiply the lower [power] sankalitam [up to the ... intentionally left blank Sources in the Development of Mathematics The discovery of infinite products by Wallis and infinite series by Newton marked the beginning of the modern mathematical era The use of...

Ngày tải lên: 05/03/2014, 22:21

... effects of the years of schooling of the head of the household, the years of schooling of the money manager and the average schooling of the heads of the village households are estimated All of the ... estimates also include the following household level variables: the age of the household head, the age of the household head squared, the number of adult females in the household, the number of adult ... village banks may be more likely in poorer villages in the Northeast as well In the Northeast, the presence of village banks is negatively related to the percentage of business households in the...

Ngày tải lên: 06/03/2014, 10:20