alkoxycarbonylamino acid amides and 4 nitroanilides

... Biol Chem 2 54, 1211–1216 43 De Marco A, Petros AM, Laursen RA & Llinas M (1987) Analysis of ligand-binding to the kringle 3399 Plasminogen transitions and proteolysis 44 45 46 47 48 49 50 51 52 ... raise polyclonal antibodies [44 ,45 ] and mAbs that specifically differentiate the LBS of plasminogen K1 and K4 [ 34, 35 ,46 ,47 ] In this study, using two mAbs that allow direct and selective blockage of ... binding sites on fibrin and cells [23] and the LBS of both K1 and K4 are simultaneously occupied by lysine analogues [41 ,42 ] However, by nature of their conservative amino acids substitutions at...

Ngày tải lên: 20/02/2014, 01:20

... 4. 1.3.7) is usually found as isoenzymes in mitochondria and glyoxysomes, respectively [42 ,43 ] They usually have a molecular mass of  90 kDa and are typically homodimers of 45 -kDa subunits [44 ,45 ] ... Cell Mol Life Sci 54, 1350±13 64 105 Gray, M.W., Burger, G & Lang, B.F (1999) Mitochondrial evolution Science 283, 147 6± 148 1 106 Kurland, C.G & Andersson, S.G.E (2000) Origin and evolution of the ... MATERIALS AND METHODS Amino -acid sequences for individual plant tricarboxylic acid cycle and glyoxylate cycle enzymes and their constituent subunits were extracted from the databases and compared...

Ngày tải lên: 22/02/2014, 04:20

... supplementation with gamma-linolenic acid alters fatty acid content and eicosanoid production in healthy humans J Nutr 127, 143 5– 144 4 63 Fonteh, A.N (1999) Assessment of arachidonic acid distribution into ... 0 .49 5 1.655 0.102 1.829 0.858 1.279 5 .49 1 ± ± ± ± ± ± ± A23187 0.066 0.2 24 0.013 0. 041 0.235 0 .47 0 0.857 0.237 0.550 0.191 0.991 0.720 1. 142 2.661 ± ± ± ± ± ± ± Net Release 0.070* 0.058* 0. 141 ... Pharmacia (Piscataway, NJ, USA) and Dextran 70 from Abbot Laboratories (North Chicago, IL, USA) Arachidonic acid, leukotriene B4 (LTB4) and 20-hydroxy-leukotriene B4 were purchased from Cayman (Ann...

Ngày tải lên: 22/02/2014, 07:20

... $9,957,865 $7,087,917 $1, 744 ,44 7 $320,000 $900,000 $60,000 $20,070,229 The MSHDA Mortgage is set at 1% interest for a 40 -year term, which is the only debt on the project and is repayable from project ... Supportive Housing with Tax-Exempt Bonds and 4% Low-Income Housing Tax Credits Background on Tax-Exempt Bonds and 4% Tax Credits Tax-exempt bonds partnered with 4% Low-income Housing Tax Credits (LIHTC) ... states and bond issuing agencies, and from year-to-year based on public priorities and the demand for volume cap Bonds for multifamily housing compete directly with other infrastructure and public...

Ngày tải lên: 06/03/2014, 04:20

... Psy1 and Psy2 cDNAs were cloned in suitable vectors, sequenced and deposited in the NCBI database as EF5 347 39 and EF5 347 38 Combining these two mRNA sequences with those of GTOM5 (X6 044 1) and clone ... Results Isolation of tomato Psy1 and Psy2 genes Using the sequences M 847 4 and L2 342 4 reported in the NCBI database corresponding, respectively, to tomato Psy1 and Psy2 mRNAs, an extended database ... RT-PCR EF5 347 39 69 RT-PCR EF5 347 38 72 RT-PCR EF5 347 39 1522 Cloning EF5 347 38 16 74 Cloning Fig Comparison of the structures of the Psy1 and Psy2 genes Table Structure of tomato Psy1 and Psy2 genes...

Ngày tải lên: 07/03/2014, 05:20

... GLY170 4. 35 ASP191 GLU222 SER195 CYS 145 4. 05 2. 84 2. 84 GLN192 GLY1 94 SER195 SER195 THR223 GLY193 C D LYS96 ASP2 24 ARG96 H2O B H2O sulso H2O CYS 145 M22B H2O SER171 SER171 ARG96 SER172 CYS 145 CYS 145 ... temperature of 40 °C and the molecules eluted with 4. 5 mm HClO4 Propionamide and its acid were separated with an Rspack KC-811 (MIXED MODE) coupled with Rspack KC-G (Shodex) mm · 300 mm and monitored ... versatile program to convert, handle and visualize molecular 47 24 E Cilia et al structure on Windows-based PC J Mol Graph 21, 47 49 21 Peitsch MC (1996) ProMod and Swiss-Model: Internetbased...

Ngày tải lên: 07/03/2014, 21:20

... subtilis 4, 200,000 Closed-circular double-stranded DNA F plasmid 95,000 Closed-circular double-stranded DNA λ phage 48 ,500 Linear double-stranded DNA T7 phage 40 ,000 Linear double-stranded DNA ... Nucleic Acids Research , 2011 Jan;39(Database issue):D32-7 ) There are approximately 126,551,501, 141 bases in 135 ,44 0,9 24 sequence records in the traditional GenBank divisions and 191 ,40 1,393,188 ... sequences G pairs with C, A pairs with U, and G pairs with U bulge internal loop Nucleic Acids in Acid and Base The glycosidic bond of DNA and RNA is hydrolyzed by acids Order of stability: dA, dG

Ngày tải lên: 13/03/2014, 16:42

... Borsäureester 44 Ester anorganischer Säuren Phosphorsäureester Ester der ortho-Phosphorsäure:  Natürlich vorkommend: Als Phosphorsäurediester sind in der DNA die Nucleotide miteinander verbunden 45 Ester ... Esters berechnet werden 30 Carbonsäureester 2.6 CH-acide Ester  Ester verfügen über eine schwache Acidität des α –Wasserstoffatoms  Besonders CH-acide Ester verdanken ihre Eigenschaft der Mesomeriestabilisierung ... Diese stehen dann zur Solvatation anderer Moleküle nicht mehr zur Verfügung 20 Carbonsäureester 2 .4 Darstellung  Carbonsäuren und Alkohole reagieren langsam miteinander  Mineralsäure als Katalysator...

Ngày tải lên: 15/03/2014, 23:14

... 3.69 a 4. 62 4. 99 4. 97 3.32 4. 09 3.76 3.51 3.92 3.95 3.62 4. 16 4. 36 3.60 3.87 3.97 4. 05, 3.75 3.95, 3.73 4. 61 4. 96 4. 03 3.58 3. 74 3.70 4. 00 3 .44 3.69 3.66 a 3.87, 3.77 a a a Signals for H6a and H6b ... 3,6)-b-D-GalpNAcI-(1 ® ® 4) -a-D-Galp-(1 ® ­ b-D-GalpNAcII-(1 ® a-D-GlcpII-(1 ® a H1 H2 H3 H4 H5 H6a, H6b 4. 59 4. 96 4. 95 3.31 4. 07 3.76 3.51 3.89 3.96 3.55 4. 12 4. 39 3.59 3.66 3.96 4. 05, 3.75 4. 61 4. 02 3. 74 3.99 ... between the anomeric and linkage protons: Gal H1/Glc H6b at d 4. 95/3.75, Glc H1/GalNAcI H3 at d 4. 59/3.89, GalNAcI H1/Gal H4 at d 4. 96 /4. 39, and GalNAcII H1/Gal H3 at d 4. 61/3.96 These data ®tted...

Ngày tải lên: 17/03/2014, 17:20

... for AU4 (nM) Kd for M8 (nM) PABP PABP12 34 PABP12 PABP 34 0.67 (0.61–0. 74) 0. 74 (0.61–0.81) 1.8 (1.6–1.9) 1.5 (1.3–1.6) 3.9 (3.7 4. 1) 1.3 (1.2–1 .4) 113 (82–157) 2.9 (2.8–3.1) 7.7 (6.5–9.1) 2 .4 (2.2–2.6) ... His6-tagged proteins PABP12 34 contains the four RRM domains but not the large C-terminal domain, while PABP12 and PABP 34 contain RRM domains and 2, and RRM domains and 4, respectively (Fig 3) The ... protein specifies its binding to poly (A) RNA and its interaction with eukaryotic initiation factor (eIF) 4F, eIFiso4F, and eIF4B J Biol Chem 275, 1 745 2– 1 746 2 38 Lee, J & Bedford, M.T (2002) PABP1...

Ngày tải lên: 23/03/2014, 12:20

... 0. 24 0.10 – 0.93 0 0 .44 – – 0.07 0.98 0 .43 0.90 0. 04 0.65 0.32 0.50 0.92 0. 94 0 .45 0.21 0. 94 0.21 0 0.93 0.1 0 .42 0 .44 0.93 0.96 0.08 0.97 0.29 0 .43 0.85 0.85 0.55 0.05 0. 84 0. 24 0.96 0.95 0 0.96 ... 0. 94 0.92 0 .45 0.51 0.93 0 .48 0.02 0.93 0.01 0.07 0. 24 0.29 0.95 0.98 0.13 0.97 0.15 0.28 0.90 0.85 0. 54 0.09 0.66 0.51 0.98 0.97 0 0.96 0. 04 – – – 0 .42 0 .42 0 .45 – – 0.02 – 0.62 – – – 0. 94 – ... ND 41 ± 61 ± 11 40 ± – ND ND ND 0–3 32 ± 56 ± 13 – ND ND ND 0–6 68 ± 12 ± 34 ± 66 ± 23 ± 6±5 0–6 63 ± 6±5 28 ± 72 ± 43 ± 27 ± 0–3 24 ± 47 ± 41 ± 59 ± 33 ± 6±6 0–10 62 ± 0–8 0 4 33 ± 65 ± 14 0–4...

Ngày tải lên: 23/03/2014, 12:20

... and J Turk, Endocrinology 139, 40 73 -40 85 (1998) 42 H C Yang, M Mosior, B Ni, and E A Dennis, J Neurochem 73, 1278-1287 (1999) 43 S K Hanks, A M Quinn, and T Hunter, Science 241 , 4~ 52 (1988) 44 ... Kennedy, and H.-E Claesson, Eur J Biochem 262, 575-585 46 47 48 49 50 51 52 (1999) 54 55 56 57 58 59 60 61 62 63 S Liu and J Mchowat, Am J Physiol 275, H 146 2-H 147 2 (1998) H Meves, Prog Neurobiol 43 , ... Biochemistry 37, 45 53~1567 (1998) 141 I Baburina and S Jackowski, J Biol Chem 2 74, 940 0- 940 8 (1999) 142 S E Barbour, A Kapur, and C L Deal, Biochim Biophys Acta 143 9, 77-88 (1999) 143 S Akiba, S...

Ngày tải lên: 05/05/2014, 16:43

... Range 45 -80 45 -89 Race White 30 94% 28 90% 58 Black 3% 10% 92% 6% Hispanic ECOG PS 3% 0% 2% 15 47 % 17 55% 32 51% 16 50% 12 39% 28 44 % 3% 6% 5% Measurable, Non-Osseous Disease Present 14 44% 13 42 % ... 10 :40 7 -41 5 doi:10.1186/ 147 9-5876-8-20 Cite this article as: DiPaola et al.: A randomized phase II trial of mitoxantrone, estramustine and vinorelbine or bcl-2 modulation with 13-cis retinoic acid, ... safety and activity of the combination in CRPC and found evidence of activity including complete responses in measurable disease [ 14] Clearly, further efforts are needed to understand and target...

Ngày tải lên: 18/06/2014, 16:20

... Ihara Y: Visualization of Aβ 42 (43 ) and A 40 in senile plaques with endspecific Af3 monoclonals: Evidence that an initially deposited species is A 42 (43 ) Neuron 19 94, 13 :45 -53 Naslund J, Thyberg ... CHO apolipoprotein E 4 CHO apolipoprotein E ε3 CHO apolipoprotein E 4 CHO apolipoprotein E ε3 CHO apolipoprotein E 4 CHO apolipoprotein E ε3 CHO apolipoprotein E 4 Aβ1 -40 1.0 ± 0.l-fold 1.0 ... amyloid J Biol Chem 19 94, 269:2 340 3-2 340 6 Zhou Z, Smith JD, Greengard P, Gandy S: Alzheimer amyloid-β peptide forms denaturant-resistant complex with type ε3 but not type 4 isoform of native apolipoprotein...

Ngày tải lên: 19/06/2014, 22:20

... prostaglandin E synthase and upregulation of cyclooxygenase-2 by 9-cis retinoic acid Prostaglandins Other Lipid Mediat 20 04, 74: 61- 74 Subbaramaiah K, Cole PA, Dannenberg AJ: Retinoids and carnasol ... (SAF200506 242 -C03-01 and 03) Alique is a fellow of the Spanish Ministry of Education and Science We thank Dr H Kagechika (Tokyo Medical and Dental University, Tokyo, Japan) for LE 540 and HX531 and Dr ... present in the brain and spinal cord of adult rats and mice [6,7] and are involved in functions such as spatial learning and memory [8,9] ATRA is the carboxylic acid form of vitamin A and is considered...

Ngày tải lên: 19/06/2014, 22:20

... 19 94) 47 -55 INSPEC: A 941 7-8630F-002, B 940 9- 841 0E-002 20 D.A.J Rand/ Journul oj’Power Scm~es 60 (1996) I-1 24 B2 14 Electrochemical kinetics of anodic layer formation and reduction on antimony and ... for lead -acid battery D.A.J Rand/ Journal of Power Sources 60 (1996) 1-1 24 In K.R Bullock and D Pavlov (eds.), Advances in LeadAcid Batteries, Electrochem Sot., Proc Vol 84- 14, 19 84, pp 2 14- 23 B21 ... Proc Vol 86-10, 1986, pp 33 -47 CA: 105(20) 1 944 47f 8 D.A./ Rand/Journal of Power Sources 60 (19%) I-1 24 B48 Positive pole corrosion in lead -acid batteries T Take and K Akuto Nn Electr Commun...

Ngày tải lên: 05/07/2014, 20:21

... 6.7 14. 7 43 .6 2.0 - - - 15.8 0.5 0 .4 1.1 - 14. 4 0.7 e 25.9 28.8 28.7 - - 7 .4 1.5 3.3 - 0.3 - - 4. 0 0.1 b 8.8 36.6 40 .5 - - - - 14. 0 - - - - - - e 0 .4 21.8 4. 5 0.9 2.5 12.3 0.8 6 .4 6.2 41 .1 4. 1 ... total) 14: 0 16:0 16:1 16:2 16:3 16 :4 18:0 18:1 18:2 18:3 18 :4 20 :4 20:5 22:6 Ref Phaeodactylum 9.2 26.8 45 .4 - - - 0.7 4. 6 - - - - 12.3 1.1 a tricornutum 9 .4 23.7 35.8 - - - 6.0 3.3 4. 4 3.2 0.2 ... 3.0 - 46 .0 1.0 - c 19.8 - 5.2 - - 18.2 10.2 14. 3 14. 3 - 14. 0 4. 3 - e Nostoc commune 0.3 - 43 .5 25.3 11.3 24. 1 0 .4 - - - 1.5 - 6.9 - 19.3 12.5 16.3 38.1 - - - - d e Synechocystis sp 13 .4 26.5 43 .6...

Ngày tải lên: 11/08/2014, 11:21

... Histopathologic and clinical study of 11 cases J Oral Pathol Med 20 04, 33(2):115-20 Narins RS, Brandt F, Leyden J, et al.: A randomized, double-blind, multicenter comparison of the efficacy and tolerability ... capsule utable to local injection of hyaluronic acid and not to previous local trauma Further studies are necessary to determine the underlying mechanism and the causes of this cyst formation Conclusions ... in the surgical treatment and in the follow-up of this patient, MT: drafted the manuscript and reviewed the literature, FMA: participated in the surgical treatment and in the follow-up of this...

Ngày tải lên: 11/08/2014, 20:20