... Trang 1Alternative splicing: regulation of HIV-1 multiplicationas a target for therapeutic action Jamal Tazi1, Nadia Bakkour1, Virginie Marchand2, Lilia Ayadi2, Amina Aboufirassi1and Christiane ... to p300⁄ CBP coactivators J Virol 76, 9724–9734 34 Kuramitsu M, Hashizume C, Yamamoto N, Azuma A, Kamata M, Yamamoto N, Tanaka Y & Aida Y (2005) A novel role for Vpr of human immunodeficiency ... HIV and AIDS: 20 years of science Nat Med 9, 839–843 2 Barbaro G, Scozzafava A, Mastrolorenzo A & Supuran CT (2005) Highly active antiretroviral therapy: current state of the art, new agents
Ngày tải lên: 06/03/2014, 09:22
... size, it has a decided advantage in ease of absorption “This breed can be traced back for 2,000 years and was always famous for dairy purposes In temperament, these animals are quiet and docile, ... harm Nature is always endeavoring to maintain a normal standard against any agent or condition that may attempt to alter it And when temporarily or accidentally that standard may be departed ... head f the tub, or some contrivance such as a water bad, air cushion or canvas strap Do not keep the head bent forward at an unnatural angle to keep it out of the water Breathe deeply, and occasionally
Ngày tải lên: 15/03/2014, 00:20
Báo cáo Y học: The S100A8/A9 protein as a partner for the cytosolic factors of NADPH oxidase activation in neutrophils doc
... contaminant [15] The identity of S100A8 was further ascertained by amino-acid sequencing, using Edman degra-dation As S100A9 has a blocked N-terminal amino acid, analysis of the protein was carried ... amount of arachidonic acid determined for each assay of oxidase activation [12] The rate of O2 production by the activated NADPH oxidase was calculated from the rate of the superoxide dismutase-inhibitable ... p47phox and Rac was maintained at a value of 4, i.e a nonsaturating concentration with respect to p47phox and Rac2 (cf Fig 3A) The concentration of flavocytochrome b was maintained at a fixed value, and
Ngày tải lên: 18/03/2014, 01:20
Báo cáo khoa học: Hematopoietic differentiation from human ESCs as a model for developmental studies and future clinical translations Invited review following the FEBS Anniversary Prize received on 5 July 2009 at the 34th FEBS Congress in Prague docx
... a CD34+hESC-derived starting popu-lation has been considered as a potential AIDS therapy, and as a way to alleviate secondary effects produced by anti-retroviral drugs [16] Various studies have ... demonstrating that placenta can yield higher amounts of HSCs than umbilical cord blood, and further suggesting that placenta could be banked and used for clinical transplant in a similar way to ... clinical application as well as their use as tools for pharmaceutical research and drug discovery being a major impetus for such investigations [2] The study of human hematopoiesis using hESCs and
Ngày tải lên: 22/03/2014, 17:20
Báo cáo khoa học nông nghiệp " Nutrient recovery by rice crops as a treatment for aquaculture solid waste: crop yield, nutrient status and nutrient budgets " doc
... fishpond solid waste was applied before planting as was 50 % of the inorganic P and K The remaining P and K was applied at panicle initiation stage at 35 days after sowing (DAS) while N was split 3 ... (Page et al 1982), plant analysis (Chapman and Pratt, 1961); water and wastes samples analysis followed methods for chemical analysis of water and wastes (MCAWW) EPA/600/4/79-020 revised March ... stated that most intensively cultivated paddy fields in Asia had negative K balance Potassium balance depended on many factors such as water source, K adsorption by soil, straw management and
Ngày tải lên: 21/06/2014, 04:20
Báo cáo khoa học: "Near infrared analysis as a tool for rapid screening of some major wood characteristics in a eucalyptus breeding program" ppsx
... The meal was mixed and then 15 g was removed with a spatula for disk samples and about 5 g for extreme value samples and placed in a sample cup After the samples had been scanned under a near in-frared ... screening A value of above 3.0 is regarded as satisfactory for screening (for example in plant breeding), values of 5 and upward are suitable for quality control analysis, and values of above 8 are ... (NIRS) is a highly promising method that could be adapted for rapid measurements on wood NIRS analysis is a fast, environment-friendly analytical method that has gained widespread acceptance in
Ngày tải lên: 08/08/2014, 14:20
Báo cáo khoa học: "An evaluation of decapitation as a method for selecting clonal Quercus petraea (Matt) Liebl with different branching intensities" ppt
... determinate and there are 1 or more growing season which are, in part, under endogenous control (Barnola et al, 1986; Alatou et al, 1989; Barnola et al, 1990; Par-mentier et al, 1991; Barnola et al, ... temperature was a small 3-way interaction (table I), the data for both warm and cool chambers have been com-bined (fig 5) There were no sylleptic branches For plants under all conditions there ... physio-logical state reflecting the differences between acrotony (apical control) and apical dominance (Brown et al, 1967; Champagnat et al, 1971; Champagnat, 1978; Crabbé, 1987; Champagnat, 1989)
Ngày tải lên: 08/08/2014, 19:21
Báo cáo y học: "Direct Toll-like receptor 2 mediated co-stimulation of T cells in the mouse system as a basis for chronic inflammatory joint disease" ppsx
... (Promega, Mannheim, Trang 4Germany; 1 µM) and Omniscript RT (Qiagen, Hilden, Ger-many; 4 U) The cDNA obtained was used as a template for real-time quantitative polymerase chain reaction, which was ... [27,60,61] 5 TLR ligands have been implicated by other groups as a cause of CIJD or as enhancing factors in the disease, for example hypomethylated bacterial DNA [12], LPS [13] and heat shock protein ... regulated rather markedly: a more than 10-fold decrease in TLR-1 was found in PMA/ ionomycin-treated freshly isolated B6 cells, as well as in CTL lines Whether this TLR modulation would translate
Ngày tải lên: 09/08/2014, 01:23
Báo cáo lâm nghiệp: "Diagnosing plant water status as a tool for quantifying water stress on a regional basis in Mediterranean drylands" pdf
... trees) in an area As an example, at equal vegetation covers, a forest will show more PhA than a shrub or grass vegetation so that NDVI will be much higher in the former than in the latter case [7, ... potential, usually assumed to be in equilibrium with ΨLwhen measured as Ψpd[58] The significance of both Ψpdand Ψminas indicators of plant water status has been questioned As an example, Ψpdhas been ... Trang 1Original articleDiagnosing plant water status as a tool for quantifying water stress on a regional basis in Mediterranean drylands Moreno Vertoveca, Serdal Sakçalib, Munir
Ngày tải lên: 09/08/2014, 04:20
Báo cáo y học: "Targeting Toll-like receptor signaling in plasmacytoid dendritic cells and autoreactive B cells as a therapy for lupus" pps
... we now classify INH-ODN into two categories: class B (broadly reactive) and class R (restricted reactivity) We therefore see a possible therapeutic role for class R INH-ODNs as a means to suppress ... 34 Tan EM: Antinuclear antibodies: diagnostic markers for autoimmune diseases and probes for cell biology Adv Immunol 1989, 44:93-151. 35 Casciola-Rosen LA, Anhalt G, Rosen A: Autoantigens targeted ... target TLR7 signaling pathways Based on their preferential cell reactivity, we classify INH-ODNs into class B and class R Class B (‘broadly reactive’) INH-ODNs target a broad range of TLR-expressing
Ngày tải lên: 09/08/2014, 07:20
báo cáo khoa học: " Whole-Organ analysis of calcium behaviour in the developing pistil of olive (Olea europaea L.) as a tool for the determination of key events in sexual plant " ppsx
... situ Ca2+localization showed a gradual accumulation on the stigma, and further expansion toward the style and the ovary after anther dehiscence At the post-anthesis phase, the Ca2+signal on the ... compared with flower with turgid anthers (stage 3) At this stage of flower development, a significant amount of Ca2+was also found in the anthers (Figure 2A), whereas in the petals and calyx, there ... signal molecules in plants and animals [5] and is involved in multiple signal transduction pathways, which are fundamental for many intercellular and intracellular interactions [6,7] Calcium plays
Ngày tải lên: 11/08/2014, 11:21
Báo cáo y học: " Amino acid residues that are important for Hyal2 function as a receptor for jaagsiekte sheep retrovirus" potx
... LQTHFRCQCYLGWSGEQCQWDHRQAAGGASEAWAGSHLTSLLALAALAFTWTL 473 Mouse LQKHFRCQCYLGWGGEQCQRNYKGAAGNASRAWAGSHLTSLLG VA ALTWTL 473 Rat LQMHFRCHCYLGWGGEQCQWN KRAAGDASRAWAGAHLASLLG VAMTLTWTL 473 ** ****:*****.***** ... and human Hyal2 at 2 days after Hyal2 plasmid transfection, at the same time we assay for JSRV vector transduction, but the cell-surface Flag signal was too low to allow reliable quantitation ... data, and drafted the man-uscript All authors read and approved the final manuscript Additional material Acknowledgements We thank Neal Van Hoeven for assistance with the FACS analysis, Roland Strong,
Ngày tải lên: 13/08/2014, 09:21
Báo cáo y học: " Chinese medicines as a resource for liver fibrosis treatment" ppsx
... 51:603-9. 26 Rino Y, Tarao K, Morinaga S, Ohkawa S, Miyakawa K, Hirokawa S, Masaki T, Tarao N, Yukawa N, Saeki H, Takanashi Y, Imada T: Reduc-tion therapy of alanine aminotransferase levels prevent ... cirrhosis ascites Largehead Atractyloidis Rhizoma, Hoelen, Aurantii Nobilis Pericarpium, Radix Ginseng, Radix Scutellariae, Magnolia Bark, Alisma Rhizoma, Radix Ophiopogonis, Atractylodis Rhizoma Fangji ... mice Gastroenter-ology 2000, 118:380-9. 75 Ikeda H, Nagashima K, Yanase M, Tomiya T, Arai M, Inoue Y, Tejima K, Nishikawa T, Watanabe N, Kitamura K, Isono T, Yahagi N, Noiri E, Inao M, Mochida S,
Ngày tải lên: 13/08/2014, 15:21
Báo cáo y học: "Vasculature deprivation – induced osteonecrosis of the rat femoral head as a model for therapeutic trials" ppsx
... reparative activities that are conventionally accepted as the epitome of revitalization of avascular dead bone Investigators have a priori endeavored to enable vascular ingrowth Accepting that ... an exaggerated revascularization of the formerly avascular femoral heads To conclude, the above alterations are unmistakably exclusive to the healing phase of osteonecrosis of the femoral head ... migration of osteoblasts and activation of osteoclasts So far so good; but medication with VEGF would also enhance the removal of dead bone and increase the formation of a mechanically weak intramembranous
Ngày tải lên: 13/08/2014, 23:20
Báo cáo y học: "A mouse plasma peptide atlas as a resource for disease proteomics" ppt
... publicly available at the PeptideAtlas site [9], which can be viewed and searched The raw data as well as the search results are also available for download from the 'Data Repository' page of the same ... Trang 8Materials and methodsSample preparation and mass spectrometry analysis The data for the mouse plasma PeptideAtlas was produced from an initial set of four reference plasma samples Each represented ... LTQ-Orbitrap mass spectrometer (Thermo-Finnigan, Waltham, MA, USA) coupled to a nanoAcquity nanoflow chromatography system (Waters, Milford, MA, USA) Database searches and building the mouse plasma
Ngày tải lên: 14/08/2014, 08:21
Marketing a country promotion as a tool for attracting foreign investment docx
... Development Authority IDA) 9 Jamaica Jamaica National Investment Promotion (JNIP) 6,8 Malaysia Malaysian Industrial Development Authority (MIDA) 6 try Jamaica's JNIP, Malaysia's MIDA, and Britain's ... other than final sales Among the mea-sures that are often advocated as appropriate intermediate mea-sures are attitudinal changes caused by advertising Those whoadvocate using an intermediate ... regional market Costa Rica and Jamaica, for example,both had preferential access to the United States market throughthe Caribbean Basin Initiative; Britain and Ireland both had pref-erential access
Ngày tải lên: 14/08/2014, 23:20
Flavor enhancement as a tool for increasing pleasantness and intakeof a snack product among the elderly
... significant interaction of day and aroma on the pleasantness ratings of the young, implicating an increase in pleasantness of the heightened aroma sample in the presence of health-related information. ... session than in the first one, whereas the pleasantness of the heightened aroma sample increased in the second tasting session compared with the first one (interaction of age group and aroma and tasting, Fð1; ... between age groups. Hedonic ratings In the pleasantness ratings, the aroma concentration had a similar effect on both age groups in the first tasting session: the heightened aroma sample was rated as...
Ngày tải lên: 03/04/2013, 21:06
Module 7: Microsoft Proxy Server 2.0 as a Solution for Internet Connectivity
... are based on LAN and demand-dial technologies that can be persistent or non-persistent. Public network segments that appear to Proxy Server as LAN interfaces are persistent, and the data rate ... accessing Internet-based Web objects. Point out that active caching updates the cache when requested and also automatically updates the cache. Passive caching updates the cache only when ... from the cache, and when to select each caching method. Use To remove content based on the If you want to Active caching Selected parameters such as HTML header information, age, and URL....
Ngày tải lên: 18/10/2013, 18:15
Module 8: Routing as a Solution for Private Network Connectivity
... Traffic Multicast Traffic Multicast Traffic Internet Multicast Mbone Server Routing and Remote Access-based Router Many organizations are including applications and protocols that are based on ... subnets and hosts can be easily managed by RIP -for- IP version 2. To automatically update the routing information at a regular interval. To authenticate routers when exchanging routing information. ... hosts can be easily managed by RIP -for- IP version 2. To automatically update the routing information at a regular interval. To authenticate routers when exchanging routing information. To authenticate...
Ngày tải lên: 18/10/2013, 18:15
Module 10: RADIUS as a Solution for Remote Access
... design, you can: Make certain that all redundant RADIUS servers use the same user account authentication database, thereby ensuring that the user accounts are available for authentication. ... that are based on the IPX/SPX protocol. AppleTalk Administer Apple Macintosh–based servers. Access Apple Macintosh–based file and print resources. Run applications that are based on the AppleTalk ... servers. • Access Apple Macintosh-based file and print resources. • Run applications that are based on the AppleTalk protocol. AppleTalk • Administer NetWare-based servers. • Access NetWare-based...
Ngày tải lên: 22/10/2013, 16:15
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