acute kidney injury in chronic kidney disease

... in the absence of these 'absolute' indications [8] Clinical studies addressing the 'optimal' timing of RRT are conflicting [9-12] In a meta-analysis, Seabra and colleagues AKI: acute kidney injury; ... RRT Introduction a result, the provision of renal support is very variable in clinical practice [5-7] Acute kidney injury (AKI) is a common problem in hospitalised patients with a reported incidence ... urine output less than 400 ml/day and would have (probably) fulfilled the urine criteria for AKI stage III The remaining 583 patients had RRT without a 300% change in creatinine or a creatinine...

Ngày tải lên: 13/08/2014, 19:20

... interleukin-1b, cross-reaction protein, interleukin-4, and interleukin-10 Our results also implied that the inflammatory responses and liver injury may be involved in nanoanatase TiO2-induced liver toxicity ... mRNA and protein expressions of several inflammatory cytokines, including nucleic factor-jB, macrophage migration inhibitory factor, tumor necrosis factor-a, interleukin-6, interleukin-1b, cross-reaction ... 10.1007/s11671-009-9393-8 NANO EXPRESS The Acute Liver Injury in Mice Caused by Nano-Anatase TiO2 Linglan Ma Ỉ Jinfang Zhao Ỉ Jue Wang Ỉ Jie Liu Æ Yanmei Duan Æ Huiting Liu Æ Na Li Æ Jingying Yan Ỉ Jie Ruan Ỉ Han...

Ngày tải lên: 22/06/2014, 00:20

... using a murine model of http://respiratory-research.com/content/8/1/60 LPS-induced lung injury Using the lung specimens, TUNEL staining and immunostaining of caspase-3, Bax, apoptosis inducing ... levels in epithelial lining fluid (ELF) in the ALI/ARDS patients who survived than in those who did not [17] In addition, VEGF concentration in ELF was inversely correlated with lung injury score ... role of VEGF in the pathogenesis of acute lung injury, we first evaluated the effects of exogenous VEGF and VEGF blockade using monoclonal antibody on LPS-induced lung injury in mice Using the lung...

Ngày tải lên: 12/08/2014, 15:21

... the following: the association between predefined clinical conditions and the development of acute lung injury by using the American–European consensus definition; the frequency of lung injury development ... observational study in three Spanish teaching hospitals, enrolling consecutive patients who developed clinical conditions previously linked to lung injury, both inside and outside the intensive care ... in two ways First, our finding that most patients entering the ICU do so on the day of developing their clinical insult is new, and it under-scores the potential need for rapid intervention in...

Ngày tải lên: 13/08/2014, 08:20

... underestimating the degree of change in GFR [17, 18] Acute kidney injury network criteria for staging acute kidney injury In 2005 the Acute Kidney Injury Network (AKIN) was formed, comprising a group ... ADQI = Acute Dialysis Quality Initiative, AKI = acute kidney injury, AKIN = Acute Kidney Injury Network, ATN = acute tubular necrosis, AUC = area under the curve, CKD = chronic kidney disease, ... for detecting AKI, including two serum and three urine biomarkers: Serum neutrophil gelatinase lipocalin (sNGAL) and cystatin C, and urinary kidney injury molecule 1 (KIM-1), interleukin-18 (IL-18)...

Ngày tải lên: 13/08/2014, 20:21

... by fine-tuning inflammation The role of PTX3 in determining MSCs’ effects might merit further scrutiny Keywords: Acute respiratory distress syndrome, Acute lung injury, Stem cells, Pentraxin 3, ... acute lung injury (PBS = acid aspiration acute lung injury + intraperitoneal (i.p.) PBS treatment in 1 h; WT-MSCs = acid acute lung injury + i.p PTX3-deficient MSCs treatment in 1 h) Trang 9in comparison ... act as fine-tuners of inflammation during acute lung injury We assessed the effects of adoptive transfer of MSCs in acid aspiration acute lung injury and explored the role of long pentraxin PTX3...

Ngày tải lên: 04/12/2022, 15:02

... 1NOVEL INSIGHTS ON CHRONIC KIDNEY DISEASE, ACUTE KIDNEY INJURY AND POLYCYSTIC KIDNEY DISEASE Edited by Soundarapandian Vijayakumar Trang 2Novel Insights on Chronic Kidney Disease, Acute Kidney Injury ... free online edition of this book is available at www.intechopen.com Additional hard copies can be obtained from orders@intechweb.org Novel Insights on Chronic Kidney Disease, Acute Kidney Injury ... obstetric acute kidney injury in this book Polycystic Kidney Diseases (PKD) are a group of genetic diseases affecting nearly 12 million people worldwide and there has been a significant interest...

Ngày tải lên: 23/03/2014, 17:20

... Analysis of polymorphism in Renin Angiotensin System and other related genes in South Indian chronic kidney disease patients. Clinica Chimica Acta 2009, 406:108-112. 5. Griffin KA, Bidani AK: Hypertensive ... rennin-angiotensin-aldosterone system in chronic kidney diseases. Expert Rev Cardiovac Ther 2003, 1:227-235. 11. Mayer G: ACE genotype and ACE inhibitor response in Kidney disease: a perspective. Am J Kidney Dis 2002, ... used in a total 25 μl volume. There was an initial denaturation at 94°C for 10 min. followed by 35 cycles of 1 min at 94°C, 1 min. at 55°C and 1 min at 72°C, final extension was at 72°C for 10 min....

Ngày tải lên: 11/08/2014, 03:20

... Analysis of polymorphism in Renin Angiotensin System and other related genes in South Indian chronic kidney disease patients Clinica Chimica Acta 2009, 406:108-112. 5 Griffin KA, Bidani AK: Hypertensive ... rennin-angiotensin-aldosterone system in chronic kidney diseases Expert Rev Cardiovac Ther 2003, 1:227-235. 11 Mayer G: ACE genotype and ACE inhibitor response in Kidney disease: a perspective Am J Kidney Dis 2002, ... used in a total 25μl volume There was an initial denaturation at 94°C for 10 min followed by 35 cycles of 1 min at 94°C, 1 min at 55°C and 1 min at 72°C, final extension was at 72°C for 10 min...

Ngày tải lên: 11/08/2014, 06:23

... severity for acute kidney injury based on changes in either serum creatinine or urine output from the baseline condition This allows classification of patients with acute kidney injury into one of ... to result in acute kidney injury or RIFLE class F compared with surgical admissions Progression of acute kidney injury to maximum RIFLE class The progression of acute kidney injury during the ICU ... End-stage Kidney Disease (RIFLE) class during the intensive care unit stay (days). Key messages • The RIFLE classification is a very sensitive definition of acute kidney injury: acute kidney injury...

Ngày tải lên: 12/08/2014, 23:23

... baseline renal function or eCCl < 35 ml/min per 1.73 m 2 The original pediatric Risk, Injury, Failure, Loss, End Stage Kidney Disease criteria [21] for acute kidney injury (AKI) also include ... predicted development of severe AKI in a heterogeneous group of patients with unknown timing of kidney injury Introduction Severe acute kidney injury (AKI) increases morbidity and mor-tality of ... reproduction in any medium, provided the original work is properly cited. Abstract Introduction Serum creatinine is a late marker of acute kidney injury (AKI) Urine neutrophil gelatinase-associated...

Ngày tải lên: 13/08/2014, 08:20

... developed acute kidney injury. Pulmonary dysfunction and systemic inflammatory response syndrome were present in all of the patients with acute kidney injury and developed before the acute kidney injury. ... aggravating factor in acute kidney injury in 48%. Extensive deep burns (25% or more full thickness burn) increased the risk for developing acute kidney injury early (risk ratio 2.25). Conclusions Acute ... Acute kidney injury is common, develops soon after the burn, and parallels other dysfunctioning organs. Although acute kidney injury recovered in all survivors, in higher acute kidney injury...

Ngày tải lên: 13/08/2014, 11:23

... AKI = acute kidney injury; CKD = chronic kidney disease; CPFA = coupled plasmafiltration adsorption; CRRT = continuous renal replacement therapy; ESRD = end-stage renal disease; ICU = intensive ... (CRG110600093). AKI: acute kidney injury; APACHE: acute physiology and chronic health evaluation; CI: confidence interval; CRRT: continuous renal replacement ther-apy; CVVH: continuous veno-venous ... Risk-Injury-Failure-Loss-Endstage renal disease; RRT: renal replacement therapy; SAPS II: simplified acute physiology score; SOFA: sequential organ failure assessment. Trang 2Acute kidney injury...

Ngày tải lên: 13/08/2014, 16:20

... classification [24] for acute kidney injury GFR criteria Urine output criteria Risk Increase plasma creatinine ×1.5 or GFR decrease > 25% < 0.5 ml/kg/h × h Injury Increase plasma creatinine ×2 or GFR decrease ... Physicians India 1997, 45:850-852 36 Mehta RL, Kellum JA, Shah SV, Molitoris BA, Ronco C, Warnock DG, Levin A: Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury ... Clinical review: timing and dose of continuous renal replacement therapy in acute kidney injury Crit Care 2007, 11:232 40 Baudouin SV, Wiggins J, Keogh BF, Morgan CJ, Evans TW: Continuous veno-venous...

Ngày tải lên: 13/08/2014, 19:20

... and urinalysis for albumin Adults with diabetes Serum creatinine (with eGFR) and urinary albumin–creatinine ratio (ACR) in a spot urine sample Offer CKD testing with urinary albumin–creatinine ... and Chronic Kidney Disease Kosaku Nitta 71 Metabolic Acidosis and Chronic Kidney Disease Richard M Treger and Jeffrey A Kraut 83 Acute Kidney Injury in Chronic Kidney ... Levin A, Levin N, et al The burden of kidney disease: improving global outcomes Kidney Int 2004;66:1310–4 National Kidney Foundation KDOQI clinical practice guidelines for chronic kidney disease: ...

Ngày tải lên: 09/08/2016, 18:13

... decreased by points in the Activator group, points in the manipulation group, and points in the mobilisation group A reduction in pain of at least points is considered a clinically meaningful improvement ... small sample size and, this interesting finding needs to be confirmed in larger trials Competing interests The authors declare they have no non-financial competing interests A portion of the study ... rating? J Eval Clin Pract 2001, 7:399-410 54 Wyrick K, Nienaber N, Tierney W, Wolinsky F: Linking clinical relevance and statistical significance in evaluating intra-individual changes in health-related...

Ngày tải lên: 13/08/2014, 14:20

... (protein) amino acids which can be leucine (L) and arginine (R) in microcystin LR, arginine (R) and arginine (R) in microcystin RR, Leucine (L) and tryosine (Y) in microcystin LY etc Microcystins ... cylindrospermopsin and neurotoxins such as anatoxin-a, anatoxin-a(s) and saxitoxins, the marine toxin aplysiatoxin, debromoaplysiatoxin and lyngbyatoxin-a), and lipopolysaccharides (LPS) All are biotoxins ... liver exhibiting centrilobular necrosis 10 Other variants of cylindrospermopsin are demethoxy-cylindrospermopsin and deoxy-cylindrospermopsin Figure 3: Cylindrospermopsin Cylindrospermopsin is hydrophilic,...

Ngày tải lên: 11/09/2015, 10:14

... (culture, industry, etc.) could influence the results 23 Thus, examining these relationships in other contexts would provide useful information to further test the generalizability of our findings ... set of analyses indicate that individual performance is the most significant factor to determine financial rewards In other words, performance levels in a given time period were indeed associated ... associated 11 with long-term incentives As a result, in many situations, gaining a long-term incentive does not translate into a form of pay with immediate spendable value The vesting or other restrictions...

Ngày tải lên: 11/09/2013, 11:44

... obtaining market share in loan markets because of their more prominent stature In any event, the movement into lending represents an increase in the value of output produced and an improvement in ... improvements or changes in the exercise of market power in setting prices There is a substantial dispersion in the findings some mergers appear to result in large increases in efficiency, whereas ... find acquiring banks to be more efficient than the banks they acquire, this suggests an improvement in total efficiency from mergers, Since they include an output index as well as an input index,...

Ngày tải lên: 06/03/2014, 08:21

... quantities of protein utilizing the principle of protein-dye binding Anal Biochem 72, 248–254 55 Marchini C, Angeletti M, Eleuteri AM, Fedeli A & Fioretti E (2005) Aspirin modulates LPS-induced nitric ... staining carry, respectively, the wild-type and a mutant p53 gene This mutation consists of a single G fi A transition in codon 237, resulting in a missense mutation of methionine to isoleucine ... and T-L components being the most in uenced activities We also demonstrated that TQ induces a U-shaped inhibition in proteasome complexes through the binding of two distinct sites with different...

Ngày tải lên: 15/03/2014, 11:20