abc of spinal cord injury

... limb func-tion is one of the most common sequelae in central ner-vous system injury [1,2] In the case of spinal cord injury (SCI), the upper limb is affected in more than 50% of cases [3] Upper ... included in the study: age 16 to 65 years, injury of at least 6 months’ duration and level of injury C6 or C7 classified according to the American Spinal Injury Association (ASIA) [25] scale into ... characteristics of the CG were similar to those of the two groups of patients with SCI (Table 1) All subjects were right-handed In the case of subjects with C6 and C7 tetraplegia, the etiology of injury

Ngày tải lên: 19/06/2014, 08:20

... individuals with incomplete spinal cord injury Address: 1 Division of Kinesiology, University of Michigan, Ann Arbor, MI, USA, 2 Department of Mechanical Engineering, University of Michigan, Ann Arbor, ... pattern and reduce their muscle activation The goal of this study was to test the effects of robotic assistance in subjects with incomplete spinal cord injury using pneumatically powered ankle-foot ... neural control of walking [27-30] Individuals with incomplete spinal cord injury typically exhibit abnormal ankle kinematics and deficits in top speed during walking due to lack of propul-sion

Ngày tải lên: 19/06/2014, 10:20

... with incomplete spinal cord injury Methods: We tested six volunteers with incomplete spinal cord injury and six volunteers with intact nervous systems Subjects with spinal cord injury walked on ... manual assistance Variability of the kinematic profile at the ankle joint decreased when subjects with spinal cord injury were EMG profiles for subjects with spinal cord injury walking with (MA) and ... and kinematic profiles of control subjects with the profiles of each spinal cord injury subject with and without man-ual assistance [33-35] where x i and y i are two series of data, and i =

Ngày tải lên: 19/06/2014, 10:20

... recovery after transplantation of ASCs into the areas of spinal cord injury in vivo was reported in rodent models of SCI [18] Rodent spinal cords are smaller than canine cords and are also anatomically ... transplantation of ASCs in dogs with spinal cord injury may be partially due to the neural differentiation of implanted stem cells. Keywords: adipose-derived stem cells, dog, spinal cord injury, ... fluorescence was identified in cytoplasm of cells 48 h after transfection with a fluorescent microscope (Fig 2B) Induction of spinal cord injury Spinal cords of the experimental dogs under general

Ngày tải lên: 07/08/2014, 23:22

... the white matter of the spinal cord distal to the LC(Figure 4B), whereas ramified Figure 1 Proteome analysis of the lesion center of the injured spinal cord (A) The injured spinal cords were collected ... number of apoptotic cells in the injured spinal cord compared to those found in the injured spinal cord without any treat-ment (Figure 2B) Extensive inflammation in the injured spinal cord in ... of spinal cord contusive injury Chih-Yen Wang1, Jen-Kun Chen2, Yi-Ting Wu2, May-Jywan Tsai3, Song-Kun Shyue3, Chung-Shi Yang2,4*, Shun-Fen Tzeng1* Abstract Background: Traumatic spinal cord injury

Ngày tải lên: 10/08/2014, 05:21

... thoracic spinal cord J Neurosci 22:6670-6681 156 Tator CH (1995) Update on the pathophysiology and pathology of acute spinal cord injury Brain Pathol 5:407-413 Tator CH, Fehlings MG (1991) Review of ... Model of Spinal Cord Injury Molecular neurobiology Zhang L, Ma Z, Smith GM, Wen X, Pressman Y, Wood PM, Xu XM (2009) GDNFenhanced axonal regeneration and myelination following spinal cord injury ... after cervical spinal cord injury, PLoS One, doi:10.1371/journal.pone.0030012 2011 Walker, CL and Xu, XM Morphological Assessments Following Spinal Cord Injury In: Animal Models of Acute Neurological

Ngày tải lên: 24/08/2014, 09:14

... site of rostral perilesion at day 21 after SCI.Parasagittal section of rat spinal cord labeled with BrdU (green) and DAPI (blue) in SCI, SCI+MT, and SCI+MT+Ex groups at day 21 after spinal cord injury ... mixture of expectation and skepticism Therapies for spinal cord injury have been promised almost since the dawning of the stem cell approaches Although stem cell therapy, like many in the field of spinal ... These cells can be isolated and expanded for transplantation from spinal cord [12,13] In response to injury, eNSPCs of the spinal cord have been shown to proliferate and mature into oligodendrocytes

Ngày tải lên: 01/11/2022, 08:56

... weeks post-spinal cord injury (SCI) (B, C) The total estimated number of BrdU+NG2+cells using Stereo Investigator software in a 2-mm segment of spinal cord centered on the site of injury was ... the spinal cord at a predetermined impact force of 50 kdynes (moderate injury) and the mice were in-jured by a rapid displacement of the impounder resulting in a spinal cord displacement of 400 ... 2-mm long spinal cord segments 7 weeks after SCI Supporting our finding of increasing numbers of (Figure 2D), we found significantly more CC1+ cells (P = 0.04) in the injured spinal cord of IκBα-dn

Ngày tải lên: 02/11/2022, 11:41

... validity of a Spinal Cord Injury Secondary Conditions Scale J Spinal Cord Med 2007;30:131 –9. 69 Peter C, Cieza A, Geyh S Rasch analysis of the General Self-Efficacy Scale in spinal cord injury ... variants in spinal cord injury research: a systematic review. J Spinal Cord Med 2014;37:128 –38. 67 Forchheimer M, McAweeney M, Tate DG Use of the SF-36 among persons with spinal cord injury Am ... for the time of assessment. SCI, spinal cord injury; SwiSCI, Swiss Spinal Cord Injury Cohort Study. Trang 7A large majority of persons with SCI were SPAmembers (88%) In total, 37.4% of the sample

Ngày tải lên: 04/12/2022, 15:07

... neurological classification of spinal cord injury (revised 2011). J Spinal Cord Med 2011;34:535–46. [40] International Association of Neurorestoratology Spinal cord injury functional rating scale ... patients with subacute and chronic spinal cord injury Cell Transplant 2006;15:675–87. [3] Yoon SH, Shim YS, Park YH, Chung JK, Nam JH, Kim MO, et al Complete spinal cord injury treatment using autologous ... invasive delivery of stem cells for spinal cord injury: advantages of the lumbar puncture technique J Neurosurg Spine 2004;1:330–7. Shumsky JS, Neuhuber B, et al Lumbar puncture delivery of bone marrow

Ngày tải lên: 04/12/2022, 16:07

... National Spinal Cord Injury Statistical Center: Spinal cord injury Facts and figures at a glance J Spinal Cord Med 2005, 28:379-380 Ackery A, Tator C, Krassioukov A: A global perspective on spinal cord ... transplantation and spinal cord injury Neurosurgery 2000, 47:691-700 Houle JD, Tessler A: Repair of chronic spinal cord injury Exp Neurol 2003, 182:247-260 Schwab ME: Repairing the injured spinal cord Science ... (OECs) in the distal and proximal cord stumps and infusion of chondroitinase ABC to the SC bridge/host spinal cord interface was studied in a rat model of spinal cord transection [79] OECs were

Ngày tải lên: 19/06/2014, 10:20

... nerve injury [5] Several studies demonstrated increased TNFα levels in DRG [6-8] and spinal cord [9-11] in different models of peripheral neuropathy The main sources of cytokines in the spinal cord ... Institute of Physiology, Academy of Sciences of the Czech Republic, Prague, Czech Republic Authors: Diana Spicarova, Ph.D Department of Functional Morphology, Institute of Physiology vvi, Academy of ... or incubation of spinal cord slices with TNFα modulates excitatory [13-16] and inhibitory [17, 18] synaptic transmission in the spinal cord DH Furthermore, intrathecal application of exogenous

Ngày tải lên: 19/06/2014, 22:20

... of the spinal cord causes atrophy of significant numbers of red nucleus neurons, a process that begins approximately 1 week after spinal cord injury [29] F Fiigguurree 88 Grid-walk analysis of ... therapies, with the treatment of spinal cord injury being one of the primary targets for early translation of laboratory efforts to clinical trials A variety of cell types of both non-CNS and CNS origin, ... repairing the injured adult spinal cord In contrast to the lack of effect of astrocyte transplantation regeneration, neuroprotection and functional recovery after acute spinal cord injury [14] The ability

Ngày tải lên: 06/08/2014, 18:21

... surae muscle after spinal cord injury in mice Zaghloul Ahmed*1,2, Robert Freedland2 and Andrzej Wieraszko2,3 Abstract Background: From the onset to the chronic phase of spinal cord injury (SCI), peripheral ... investigate the changes in excitability of the sciatic nerve and to characterize the properties of muscle contractility after contusive injury of the mouse thoracic spinal cord Results: The following changes ... the duration of PMCT indicates that post-injury axonal changes lead to an increase in the conduction velocity along the whole motor nerve from the spinal cord to the site of the recording electrode

Ngày tải lên: 10/08/2014, 10:20

... exposed spinal cord with a mechanical device that displaces the spinal cord by a preselected amount The contusion injury model seems to be the most relevant to human spinal cord traumatic injury ... urethral sphincter in a rat model of spinal cord injury: effect of injury severity J Neurosci 2001, 21:559-569. 5 Chang S, Mao ST, Hu SJ, Lin WC, Cheng CL: Studies of detrusor-sphincter synergia ... following spinal cord injury J Neurochem 2007, 101:182-200. 29 Pannu R, Barbosa E, Singh AK, Singh I: Attenuation of acute inflammatory response by atorvastatin after spinal cord injury in

Ngày tải lên: 11/08/2014, 03:20

... urethral sphincter in a rat model of spinal cord injury: effect of injury severity. J Neurosci 2001, 21:559-569. 5. Chang S, Mao ST, Hu SJ, Lin WC, Cheng CL: Studies of detrusor-sphincter synergia ... following spinal cord injury. J Neurochem 2007, 101:182-200. 29. Pannu R, Barbosa E, Singh AK, Singh I: Attenuation of acute inflammatory response by atorvastatin after spinal cord injury in ... Histological and immunofluo- Figure 6 Simvastatin improves histomorphology of spinal bladder evaluated at 14th day after SCI in rats. Histomorphology of spinal bladder of sham (a-c), vehicle

Ngày tải lên: 11/08/2014, 06:22

... sharp meniscus of contrast; spinal cord deviated away from mass; ipsilateral subarachnoid space enlarged up to mass Intramedullary masses Location: inside spinal cord Tissues: cord parenchyma, ... characteristic of ABCs.20 Grossly, ABCs are multiloculated, expansile, highly vascular osteolytic lesions that often contain blood degradation products Histologically, ABCs consist of thin-walled, ... etiologies, not the hemangioma.4 Approximately 20% of VHs present with progressive neurologic deficits or symptoms of acute spinal cord compression Progression of an asymptomatic or painful lesion to a

Ngày tải lên: 29/12/2020, 17:07

... (From Nesathurai S The Rehabilitation of People With Spinal Cord Injury: A House Officer’s Guide © Boston Medical Center for the New England Regional Spinal Cord Injury Center Boston, MA: Arbuckle ... Veins of the Spinal Cord drain mainly into the internal venous plexus FIGURE 7–4. Arterial and venous supply to the spinal cord (transverse section). Trang 6SPINAL PATHOLOGYTYPES OF CERVICAL SPINAL ... dislocation of the vertebral body. B: posterior view. FIGURE 7–8. Cervical spine hyperextension injury. B A Trang 8TABLE 7-1. Spinal Cord and Pathology Associated with Mechanism of InjuryTypes of Spinal

Ngày tải lên: 04/03/2021, 13:58

... and family to develop a plan of rehabilitation and care The statutory definitions of brain and spinal cord injury are:  A spinal cord injury is a lesion to the spinal cord or cauda equina, resulting ... Trang 1BRAIN AND SPINAL CORD INJURY PROGRAMFISCAL YEAR 2010 - 2011 ANNUAL PERFORMANCE REPORT March 1, 2012 Trang 2TABLE OF CONTENTSBrain and Spinal Cord Injury ProgramTrang 3Table of Figures iiExecutive ... to improve the percentage of referrals made within ten days of the date of injury Trang 19DATA AND STATISTICSBrain and Spinal Cord Injury ProgramIndicator 3 - Percent of BSCIP-Eligible Clients

Ngày tải lên: 19/10/2022, 01:20

... function is normal Spinal reflexes after cord injury Note: Almost one third of patients with spinal cord injury examined within 1–3 hours of injury have reflexes Plantar reflex after cord injury Distinguish ... alcohol ABC OF SPINAL CORD INJURY 25 Management of spinal cord injury in an acute specialised unit is associated with reduced mortality, increased neurological recovery, shorter length of stay ... Neurological Classification of Spinal Cord Injury. Reproduced from International Standards for Neurological Classification of Spinal Cord Injury, revised 2000. American Spinal Injury Association/International...

Ngày tải lên: 17/02/2014, 19:20