a novel system for biomass utilization

... new strategy that combines the strengths of two different MA schemes such that to guarantee a good tradeoff between fairness and AME 1.1 System Model Consider a single-antenna Gaussian MA channel ... smaller than the minimum rate for TS Next, we demonstrate by simulations the capabilities of various MA schemes 3 Simulation Results 3.1 Evaluation Criteria As it was already mentioned, the fairest ... show the Average AME for the six methods which are compared As it was already pointed out previously, OMA achieves always the maximum possible AME We can notice fromFigure 2(b)that SIC and TS yield

Ngày tải lên: 21/06/2014, 11:20

... signatures as input data: a Hidden Markov Model [3] and a Gaussian Mixture Model [14] For performance assessment, both skilled and random forgeries are considered Ten random samplings are carried ... sigsig-natures randomly sampled in equal number in each Personal Entropy category (10 random forgeries per category) are considered for both databases The False Acceptance and False Rejection Rates are ... verification by a human expert A human operator labels signatures according to both criteria and their impact on performance is studied Also in [20], signature analysis by means of fractal geometry

Ngày tải lên: 21/06/2014, 19:20

... mobility situation and low traffic density situation are main performance challenges for application systems To evaluate the applicability of ERS we analyze the average accumulation speed for vehicles ... the reputation adap-tation mechanism, that is, the algorithm for repuadap-tation value accumulation and the degradation function D( ) for reputation decrease, can be flexibly defined and constructed ... simple assumption may not be practical in a real world First of all, some types of traffic events (e.g., traffic jam) usually change their status such as an inaccurate warning message may be broadcast

Ngày tải lên: 21/06/2014, 23:20

... efficiency allows us to use large 4-gram language models in a single pass of the decoder Other approaches are forced to use a smaller language model in the first pass and rescore with a larger language ... good performance, while main-taining a very low latency for stream-based operation The impact of its errors on the ASR performance is small (0.5% absolute) when compared with hand-labeled audio ... has a good real-time performance, although the results for European Portuguese are not yet at the level of the ones for languages like English, where much larger amounts of training data are available

Ngày tải lên: 22/06/2014, 20:20

... are Data bus Adjacent PEs Data bus Adjacent PEs ICS ALU (mul, add, sub, comp) Register Embedded SRAM Data bus Data (a) Data bus Adjacent PEs Data bus Adjacent PEs ICS Multiplier (MAC, MAS) Accumulator/subtractor ... modeled Standard PE Trang 10Data bus Adjacent PEs Data bus Adjacent PEsICS Inter PE bus ALU (mul, add, sub, comp) Inter PE bus Embedded SRAM Data bus Address Data bus Adjacent PEs Data bus ICS ALU ... program 1 execution Unit chip 2: program 1 execution Unit chip 3: program 1 execution Data frame buffer Data frame buffer Data frame buffer Data frame buffer Data memory Data memory Data memory Data

Ngày tải lên: 22/06/2014, 23:20

... hypoxia An enzymatic hypoxia system (GOX/CAT) based on the use of glucose oxidase (GOX) and catalase (CAT) that allows induction of stable hypoxia for in vitro approaches more rapidly and with ... order to evaluate cellular metabolism Cell proliferation after photon irradiation was investigated for evaluation of radioresistance under normoxia and hypoxia using both a hypoxia chamber and the ... GO-analysis Pathway analysis was performed based on information available on cellular signalling processes from a curated database on signalling networks and sys-tems biology package (Metacore, Genego,

Ngày tải lên: 09/08/2014, 09:20

... SL and TS evaluated and interpreted SNP microarray and aCGH data All authors read and approved the final manuscript for publication Acknowledgments We thank the heterotaxy patients and families ... quality at each aligned base position which serves as the basis for variant calling Variants are reported based on a configurable formula using the following additional parameters: depth of coverage, ... using traditional genetic approaches Although functional analyses of rare variants in the Nodal pathway have been performed that confirm their deleterious nature, in many cases these variants are

Ngày tải lên: 09/08/2014, 23:20

... receptor: a potential molecular imaging marker for human cancer Neoplasia 2003, 5:495-506. 37 Maranga L, Rueda P, Antonis AF, Vela C, Langeveld, J.P., Casal JI, Car-rondo MJ: Large scale production and ... albumin and transferrin Photochem Photobiol 2000, 72:234-241. 33 Sato Y, Yamauchi N, Takahashi M, Sasaki K, Fukaura J, Neda H, Fujii S, Hirayama M, Itoh Y, Koshita Y, Kogawa K, Kato J, Sakamaki ... gradi-ent also suggested VLP preparation has packaged variable amounts of nucleic acids that are most likely random cel-lular RNA since the particles assemble in the cytoplasm (data not shown) Gradient

Ngày tải lên: 11/08/2014, 00:22

... Trang 1Open AccessResearch Polymeric nanoparticle-encapsulated curcumin ("nanocurcumin"): a novel strategy for human cancer therapy Savita Bisht1, Georg Feldmann1, Sheetal Soni3, Rajani ... Feldmann1, Sheetal Soni3, Rajani Ravi2, Collins Karikar1, Amarnath Maitra3 and Anirban Maitra*1,2 Address: 1 The Sol Goldman Pancreatic Cancer Research Center, Department of Pathology, Johns Hopkins University ... Savita Bisht - sbisht1@jhmi.edu; Georg Feldmann - gfeldma4@jhmi.edu; Sheetal Soni - sheetalsoni@gmail.com; Rajani Ravi - ravira@jhmi.edu; Collins Karikar - ckarika1@jhmi.edu; Amarnath Maitra

Ngày tải lên: 11/08/2014, 00:22

... (TCGA) database This dataset comprises of molecular characterizations from 373 GBM patients For each patient, the database provides copy number (level2 data 150 patients), microarray (level2 data ... interactions dataset: Network information was obtained from the National Cancer Institute's Pathway Interaction Database [12] Gene-expression analysis Pathway Consistency and Pathway Activity ... behavior [11] Interaction and pathway information were obtained from The National Cancer Institute's Pathway Interaction Database (PID) [12] We Trang 4combined pathway metrics with clinical data

Ngày tải lên: 11/08/2014, 12:21

... vision, as others have also adopted this strategy as a way forward in molecular analysis Alagaratnam et al are utilising Bayesian approaches to pursue muscular dystro-phy diagnosis [223] Similarly, ... Vaisocherova et al devised an SPR assay for detection of the candidate pancreatic cancer marker activated cell leukocyte adhesion molecule (ALCAM) that can be used to distinguish between ALCAM ... metabolomics and transcrip-tomics examine only one strand of the information available about an organism Systems biology combines data from all these fields with bioinformatic, computa-tional biology and

Ngày tải lên: 12/08/2014, 14:20

... CAAAATTCCATGACAATTGTGGTGGAATGCCACTAGAAA CAAAAAACGATGAGTATGTAGGTCCATTGCCACTAGAAA CAAAATTCCATGATTATTATGGTTTAATGCCACTAGAAA CAGAGATAGGTTTGAATGTTGTTACAGTTTGGAACAAGA GAAAATCTCTAGCAGTACTGGAAGGGCTAATTCACTCCC CAGCGGGGGTCTTTCATTAATGAAAGACCCCACCTGTAG ... junction active integrase: A T G A T T A G G A T G T A C C T A T LTR-LTR junction in PFV-1 infected cells -AA T - -A A -AGGA-A GTGTGGTGG-ATGC -10 % -CAAAATTCCATGACAATTGTGGTGGAATGCCACTAGAAA ... processing integrated DNA TGT -ACA ACA -TGT classical integration viral DNA 3’-processed at each IN-cleavage of 2-LTR molecules 2-nt lost TGT -ACAAT ACA -TGTTA IN -ACAAT TGT -TGTTA DNA with LTR-LTR

Ngày tải lên: 13/08/2014, 09:21

... of actual human physiological parameters and are linked mechanistically Therefore, the WBPBPK approach can elucidate kinetics in organs and is applicable for a variety of uses The SAC approach ... equation Using the scaled-up SAC parameters, human pharmacokinetics were simulated and each pharmacokinetic parameter was calculated These simulated parameters were compared to the observed data ... approach, which is also used to extrapolate clinical pharmacokinetic parameters, uses in vitro materi-als such as hepatocytes and microsomes to scale up to an actual target pharmacokinetic parameter

Ngày tải lên: 13/08/2014, 16:21

... cells, mouse Apo B was amplified using the primers 5' CACGT-GGGCTCCAGCATT 3'and 5' TCACCAGTCATTTCT-GCCTTTG 3' and the TaqMan hydrolysis probe 5'(FAM) CCAATGGTCGGGCACTGCTCAATA (TAMRA) 3' (cour-tesy ... Natalia Natalia, Stephanie Behnke, Karen Burns, Kelly W Maloney, Anne B Warwick and Rimas J Orentas* Address: Department of Pediatrics, Medical College of Wisconsin and the Children's Research ... large vaccine stocks that can be qualified for clini-cal use A vaccine for neuroblastoma featuring the expression of both a cytokine and a chemokine transgene (IL-2 and lymphotactin) by a single

Ngày tải lên: 14/08/2014, 19:22

... the salvage and the de novo pathways Because a yeast cell must be able to utilize at least one of these pathways to sur-vive and NMA1 is not an essential gene, NMA1 is clearly not vital for the ... (Table C in Additional data file 4) In order to validate the microarray data, we used quantitative RT-PCR to examine the expression of five of the up-regulated genes in a set of RNA samples that ... transcriptase that uses an RNA template to add telomeric DNA, chromosome ends are maintained by the addition of DNA repeats [4] In budding yeast and mammalian cells not expressing telomer-ase, telomeres

Ngày tải lên: 14/08/2014, 21:20

... health care industry [22] The latter is ofparticular importance, because it can positively affect many persons and in some Trang 2ro-areas will constitute a reasonably big market that can afford ... the human and for stability analysis Trang 6a simple, time invariant, spring-damper-mass model for the human arm (exceptionsinclude [1]).? Stability and passivity results are based on a (usually ... so that relevant applications are computationally intensive and problem-atic for a totally unstructured and unknown environment The second group entailsthe use of wave variables to form a passive

Ngày tải lên: 26/10/2014, 14:31

... Mitra et al 2003) R00681 6 AACAAACACAA AC-box: H1TF1 (La Bella et al 1989), HiNF-A (van Wijnen et al 1988b), HiNF-D (van Wijnen et al 1996; and Heintz 1994; Gallinari et al 1989), HiNF-B (van ... intrinsically have any bias towards a particular location or orientation (Werner 1999) However for a particular class of promoters such a bias may be observed (Wasserman and Fickett 1998) Adding ... many other approaches Bayesian networks offer a natural way to represent probabilistic data (Jensen 2001) As highlighted later in the text, biological data are prone to sequencing and annotation

Ngày tải lên: 11/09/2015, 21:20

... describes diagrams by keywords and parameter-value pairs Parameter-value pairs denote the contents of diagrams such as block sample times by associating particular values withrelevant parameters ... predicates (for example, automat-a predicautomat-ate cautomat-an depend on intervautomat-al operautomat-ators, time points, or both) Tautomat-aking the ruleintroduced in Chapter 2.1 as an example, its ... and aerospace [12] application areas A Simulinkdiagram made up of blocks and wires represents a set of time-dependent mathemat- ical relationships which model a dynamic system A block can be an

Ngày tải lên: 14/09/2015, 08:23

... CAA GCG AGC CCT CCT AAA TCT GGG CCA AA GCC CAG AGC TAT CTA GTC CTA AAC CT AGC AAC CGC AAT ACT CAC AG GGA ACT CTG GAC TTG AGC ATG CAT TGA CAA GAG CCT CAG AAA CCT C GGA GAA TGA TGA GGA GAT CAA ... ACC ATG ACC AAA TCA TAC AGC GAG A REVERSE ATA TAT CTC GAG GCC ACC CTA ATC GTG AAA GAT GGC ATT AAG CT FORWARD REVERSE NEUROD1 ATA TAT CTC GAG GCC ACC CTA GAC CTG AAT GCC CC FORWARD MYT1 ATA TAT ... GA ATA TAT GCT AGC GCC ACC ATG CTG TTC CAC AGT CTG REVERSE ATA TAT ACC GGT GCC ACC ATG GCG GAG ATG AAG AGC C REVERSE ATA TAT GCT AGC GCC ACC ATG AGC TCA GAA AGT GAT GAC AAG C REVERSE ATA TAT ACC...

Ngày tải lên: 24/08/2014, 12:37

... Primer location Amplified band (bp) P553 P554 P557 P558 GTGATTCTCTGCTAGATGTTG GGCACTCGAACAGTCATATTG ATTAAGGAGCTTCGGGAGATG CTCTTATACCCAATGCTGCTG First pair GCCTTTGAGTCCATCACTAAC CCAGTGTCTTGGCAGGAATC ... of amplified message DNA ladder is marked M (A) HaCaT keratinocytes (lane 1); normal epidermal keratinocytes (lane 2); C1–4 squamous cell carcinoma (lane 3); dermal fibroblasts (lane 4); epidermal ... (lane 2) or black (lane 3) patients; melanoma WM35 (lane 4); normal epidermal keratinocytes (lane 5); HaCaT keratinocytes (lane 6); C1–4 squamous cell carcinoma (lane 7); dermal fibroblasts (lane...

Ngày tải lên: 23/03/2014, 13:20