a case for multivariate optimization and product homogeneity

... and ORF 1a overlap, ORFX has higher amino acid conservation than ORF 1a (182/ 229 identities for ORFX, 153/229 identities for ORF 1a) Next, the ORF 1a alignment was analysed for conservation at synonymous ... here (An alternative explanation In Breda virus (NC_007447), the annotated ORF 1a AUG initiation codon is at nucleotide coordinates 859 861 and the first ORFX-frame AUG codon is at coordinates ... transitions and transversions There was a striking, and highly statistically significant (p < 10-17 for the total conservation within ORFX), peak in ORF 1a- frame synonymous site conservation at the...

Ngày tải lên: 12/08/2014, 04:20

... and ORF 1a overlap, ORFX has higher amino acid conservation than ORF 1a (182/ 229 identities for ORFX, 153/229 identities for ORF 1a) Next, the ORF 1a alignment was analysed for conservation at synonymous ... here (An alternative explanation In Breda virus (NC_007447), the annotated ORF 1a AUG initiation codon is at nucleotide coordinates 859 861 and the first ORFX-frame AUG codon is at coordinates ... transitions and transversions There was a striking, and highly statistically significant (p < 10-17 for the total conservation within ORFX), peak in ORF 1a- frame synonymous site conservation at the...

Ngày tải lên: 12/08/2014, 04:20

... Preliminary data analysis revealed no significant main effects and only one significant interaction of day and aroma on the pleasantness ratings of the young, implicating an increase in pleasantness ... investigation, since there are ambiguous results and evidence for and against on that matter Acknowledgements The authors thank practical trainees Linda van Mierlo and Pascalle Weijzen from Wageningen ... bitter and more intense in currant flavor and in overall flavor, and stronger in after-taste than the sample with a regular aroma concentration The heightened aroma concentration caused a slight...

Ngày tải lên: 03/04/2013, 21:06

... Iizumi Y, Sagara H, Kabe Y, Azuma M, Kume K, Ogawa M, Nagai T, Gillespie PG, Sasakawa C & Handa H (2007) The enteropathogenic E coli effector EspB facillitates microvillus effacing and antiphagocytosis ... pathogenesis EspB as an effector of actin filament reorganization The EspB (or EarB) gene product was first identified as an important factor in EPEC attachment [14] and later characterized as a ... 2403–2408 Hamaguchi M, Hamada D, Suzuki KN, Sakata I & Yanagihara I (2008) Molecular basis of actin reorganization promoted by binding of enterohaemorrhagic Escherichia coli EspB to a- catenin FEBS...

Ngày tải lên: 29/03/2014, 09:20

... design & analysis of the study and the preparation of the manuscript All authors reviewed the final manuscript Additional material Additional file Table 1: Clinical data of both groups at study ... daily treatment session started, and the wrist scores were 2/5 (# 2) and 3/5 (#1) Passive hand care was easier, although active hand function did not change considerably; the FM scores were and ... occupational therapy every workday The major treatment goals were restoration of stance and gait, and independence in ADL About 15% of total therapy time was devoted to upper limb work, such as...

Ngày tải lên: 19/06/2014, 08:20

... issuance of qualified audit opinions (Bartov et al 2000), audit failures (Geiger and Raghunandan 2002), and auditor changes (DeFond and Subramanyam 1998), while lower accruals levels are associated ... numerous accounting studies that consider the relation between earnings management and accruals behavior, and earnings quality and accruals behavior Early studies used the change in Total Accruals as ... in Panel B, and on the raw values in Panel C for our two accruals measures Panel A reveals that the coefficients for Tenure are negative and significant for both Discretionary and Current Accruals...

Ngày tải lên: 06/01/2015, 19:43

... Sukanta Kumar Hazra and Mr Wang Haiguang Many others have contributed to making the author’s candidature at the Institute for Infocomm Research a satisfying and enlightening experience The author ... probability of a loss run, P(LA(jA) = lA), can be expressed as: P ( LA ( j A ) = l A ) = P ( A( n A − 1) = 0, A( n A − 2) = 0, , A( n A − l A ) = 0, A( n A − l A − 1) = A( n A ) = 1) , (3.4)  nA  ... ∞ that P ( LA = l A ) = where A l A( n A − l ) n A →∞ ( ), P A0 = 1, A 1 = 0, , A lA = 0, A lA −1 = P ( A0 = 1) (3.8) We assume that all packets passing through Channel A are of the same length,...

Ngày tải lên: 16/09/2015, 12:35

... increased use of IP network cameras and RFID scanners This standard allows electric power to be sent along the same cables that carry Ethernet data PoE-enabled switches and controllers can now ... five and a half months • Annual benefit per employee: $93 • Five-year ROI: 115% Financial Analysis Table on the following page contains the input data used in our analysis Table summarizes the value ... per year for a large network Among the major benefits of the ADC midspan PoE controllers are lower acquisition and installation costs; lower support, maintenance, and power costs; and increased...

Ngày tải lên: 21/12/2013, 08:17

... research and digital libraries of the future is to handle the increasing automatization of the research sources in a way that makes these resources manageable and available to a broader audience ... European Database on AIDS and HIV infection a bibliographic database focused on grey literature and educational material produced by a group of European documentation centres specialized in AIDS and ... will make your local librarian rarer and rarer[Arms 2000] Another fact that also point in that direction is that one of the major costs for classic libraries are staff, facilities and materials,...

Ngày tải lên: 24/01/2014, 00:20

... towards recording, rmance against standards, processing, summarising examining and analysing and reporting of financial deviations, taking corrective data actions and reappraising standards based ... personal interviews and obtaining information through questionnaires Social Auditor(s) must go around and meet local administration and Gram Panchayat members, particularly Panchayat Secretary and ... informal and social institutions created for managing the resources; formation of networks and forums Formal, informal and social institutions created for managing resources – natural, human,...

Ngày tải lên: 06/03/2014, 23:20

... (min-max, average, etc.) The fscan and iscan stages are replicated and are separately attached to the database tables This way, queries that access the same tables can take advantage of relations that ... common or shared data and code (to avoid stage and scheduling overhead), and separate operators that access a large common code base or common data (to take advantage of a stage’s affinity to ... a relational query execution plan and apply a dataflow approach for designing highperformance, scalable systems In the GAMMA database machine project [De+90] each relational operator is assigned...

Ngày tải lên: 07/03/2014, 14:20

... data users, is important because data move from raw state to and through datasets and databases User feedback Networking of databases Data in the supply chain Raw data collection Database management ... prepararon artớculos temỏticos para cada 21 ỏrea y la informaciún previamente publicada fue extraớda y colocada en una base de datos para la preparaciún de dichos artớculos y para su consulta durante ... Change ISIC International Standard Industrial Classification ISO International Organization for Standardization IT information technology JEMAI Japan Environmental Management Association for...

Ngày tải lên: 07/03/2014, 23:20

... A core curriculum for international health: evaluating 10 year’s experience at the University of Arizona Acad Med 1992;67:90–94 42 International Health Group Global Health Pathway Available at: ... Several associations, organizations, and institutions have recently created scholarships and fellowships for medical students to pursue international research and training The Global Health Education ... education At the same time, more quantitative data on global health in medical education should be collected Teaching the global aspects of medicine and understanding medical resources and care...

Ngày tải lên: 14/03/2014, 21:20

... standards appear here> Teamwork Below Expectations Meets Expectations Role Model Achieving ... guidance, fails to adapt style and materials to communicate straightforward information With guidance, adapts style and materials to communicate straightforward information Independently adapts ... adapts style and materials to communicate information Organizational Know-How Below Expectations Meets Expectations Role Model

Ngày tải lên: 17/03/2014, 15:20

... Nature 460, 909–913 89 Hong H, Takahashi K, Ichisaka T, Aoi T, Kanagawa O, Nakagawa M, Okita K & Yamanaka S (2009) Suppression of induced pluripotent stem cell generation by the p53–p21 pathway ... from Leukemia and Lymphoma UK, Fanconi New advances in human hematopoiesis from human ESCs Hope UK and the Fanconi Anemia Research Fund USA, and funds for research in the field of regenerative medicine ... a CD34+ hESC-derived starting population has been considered as a potential AIDS therapy, and as a way to alleviate secondary effects produced by anti-retroviral drugs [16] Various studies have...

Ngày tải lên: 22/03/2014, 17:20

... Brothers Atanu Kumar Jana Joy Lawn Indira Narayanan Chandrakant Ruparelia Harshad Sanghvi Achmad Surjono Editor: Melissa McCormick Editorial assistance: Sonia Elabd Dana Lewison Erin Wagner Artist: ... Sylvia Deganus A. M Djauhariah France Donnay Trevor Duke L Haksari Ekawaty Indarso Fatimah Masanori Fujimura Frances Ganges Adenike Grange Dasatjipta Guslihan Petra ten Hoope-Bender Ardi Kaptiningsih ... Kimberly Battista Graphic assistance and layout: Deborah Raynor Cover design: Máire Ní Mhearáin Reviewers: Youssef Al-Eissa Deema Al Imam Anna Alisjahbana Saif Al-Saif Duong Thi Cuong Gary Darmstadt...

Ngày tải lên: 22/03/2014, 22:20

... International Law No 39 (1996), and Draft Articles on the Law Applicable to Contractual and non-Contractual Obligations (2), Japanese Annual of International Law No 40 (1997) The draft includes a ... heritages? What is a characteristic aspect of a landscape in an international context? Finally, under Article 2, paragraph 7, damage means: « a) Loss of life or personal injury; b) c) loss or damage ... the same Annex 42 28 States in Africa, 32 in Asia and the Pacific region, 27 in Western Europe and other parts, 19 in Central and Eastern Europe, 27 in Latin America and the Caribbean; lastly,...

Ngày tải lên: 23/03/2014, 00:20

... J., Tomita M and Goodman K (1992) Machine Translation: A Knowledge-Based Approach Morgan Kaufmann Publishers, San Mateo, California, USA Sinclair J (1991) Corpus, Concordance and Collocation Collins, ... be regarded as an initial exploratory step into a new exciting research area There is large room for further research and discussion, especially in word disambiguation and syntax analysis And we ... from Mandarin than other regions in Mainland China One can easily spot Cantonese dialect articles in Hong Kong newspapers which are totally unintelligible to Mandarin speakers, while Mandarin articles...

Ngày tải lên: 23/03/2014, 19:20