a better model for generating test networks

3D pancreatic carcinoma spheroids induce a matrix-rich, chemoresistant phenotype offering a better model for drug testing Paola Longati1,2, Xiaohui Jia1,2, Johannes Eimer1,2,

3D pancreatic carcinoma spheroids induce a matrix-rich, chemoresistant phenotype offering a better model for drug testing Paola Longati1,2, Xiaohui Jia1,2, Johannes Eimer1,2,

... FN, COL6A1 and COL1A and membrane transporter genes ABCC1/-3/-5 was higher in 3D during the sphere formation (contact making) and compaction phase (Figure 4A and 5A) After day a steady-state -level ... performed [15] The viability rate was calculated as a percentage of the untreated cells All data were expressed as the mean ± SD of at least replicates All experiments were performed at least ... contour (Figure 1A) In contrast, MiaPaCa2 lacked any degree of cell aggregation and ASPC-1 or Capan-1 cells were aggregating without generating a compact spheroid (Figure 1A) As the Panc-1 cell line

Ngày tải lên: 05/11/2020, 07:16

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Báo cáo hóa học: " Research Article A Fluid Model for Performance Analysis in Cellular Networks" doc

Báo cáo hóa học: " Research Article A Fluid Model for Performance Analysis in Cellular Networks" doc

... paper, we have proposed and validated by Monte Carlo simulations a fluid model for the estimation of outage and spatial outage probabilities in cellular networks This approach considers BS as a ... Given that there are already n, these curves give the probability that a new user, initiating a new call at a given distance, implies an outage As an example, a new user in a cell with already 16 ... for the traditional hexagonal network The simplicity of the result allows a spatial integration of the OCIF leading to closed-form formula for the global outage probability and for the spatial

Ngày tải lên: 21/06/2014, 11:20

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báo cáo khoa học: "A statistical model for genotype determination at a major locus in a progeny test design" ppt

báo cáo khoa học: "A statistical model for genotype determination at a major locus in a progeny test design" ppt

... variability of the ovulation rate is a bias source already shown by Dnvts et al (1982 a) For example, an FF ram may have a very low breeding value for ovulation rate (compared to the mean of the FF) which ... Trang 1A statistical model for genotype determinationat a major locus in a progeny test design J.M ELSEN Jacqueline VU TIEN KHANG Pascale LE ROY Institut National de la Recherche Agronomique, ... random variables are denoted y, , y,,, y, and y respectively. 3 Notation for probabilities For ease of presentation, we shall use the same notation the denote an event as well as the value taken

Ngày tải lên: 09/08/2014, 22:22

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Báo cáo y học: "A model for generating circadian rhythm by coupling ultradian oscillators" potx

Báo cáo y học: "A model for generating circadian rhythm by coupling ultradian oscillators" potx

... Reso- nating circadian clocks enhance fitness in cyanobacteria. Proc Natl Acad Sci USA 1998, 95:8660-8664. 53. Dodd AN, Salathia N, Hall A, Kevei E, Toth R, Nagy F, Hibberd JM, Millar AJ, Webb AAR: ... feedback inhibition and feedforward stimulation of mRNA transcription and translation are thought to be critical for many circadian mechanisms, and genes coding for essential components of circadian ... ingly, it was the circadian clock in Drosophila that prompted the modeling of circadian rhythms as coupled ultradian ones [12], and this proposal was based partly on data showing ultradian peaks in

Ngày tải lên: 13/08/2014, 23:20

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Báo cáo y học: "Cross-species cluster co-conservation: a new method for generating protein interaction networks" docx

Báo cáo y học: "Cross-species cluster co-conservation: a new method for generating protein interaction networks" docx

... where functional information was available While this is appropriate... versatile Gram-negative bacterium that also thrives in soil, marshes and coastal marine habitats, and on plant tissues [32] ... organisms that range from closely to distantly related Construction... is likely noise Addressing this limitation is an important area for continued effort Data availability Data are available upon ... formation at the air-liquid... Gamma Gram-negative and one low G+C bacteria (B subtilis) were used to evaluate the CCC method Substantial experimental data exist for all six bacteria The gammaproteobacteria

Ngày tải lên: 14/08/2014, 08:20

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A simulation by using cohesive zone model for indentation test in thin film substrate systems

A simulation by using cohesive zone model for indentation test in thin film substrate systems

... indentation load and a critical Trang 15indentation depth associated with the initial delamination crack at the thin film/substrate interface, and using the mechanical analysis, the general properties ... displacement can be called as “cohesive law” or “Traction-Separation law” When an extended is force applied to the models, the upper and lower surfaces separate gradually, after the separation ... Mulhearn’s mechanism to a cavity in an elastic-plastic material being expanded by internal pressure He found that the elastic modulus of material played a critical role in this deformation mechanism

Ngày tải lên: 26/09/2015, 09:56

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a comprehensive model for real gas transport in shale formations with complex non planar fracture networks

a comprehensive model for real gas transport in shale formations with complex non planar fracture networks

... semi-analytical model against a numerical model and an analytical model Subsequently, the effects of various gas flow mechanisms and fracture network complexities on well performance and rate transient ... numerical model and analytical model Analytical and semi-analytical approaches have also been developed to investigate the well performance in complex fracture networks Zhou et al (2013) proposed a semi-analytical ... fracture; Case is the non-planar hydraulic fracture; Case is the simple planar natural fracture; Case is the non-planar natural fracture; Case is the simple planar natural fracture network; Case is

Ngày tải lên: 08/11/2022, 14:56

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Báo cáo khoa học: "A Bayesian Model for Unsupervised Semantic Parsing" ppt

Báo cáo khoa học: "A Bayesian Model for Unsupervised Semantic Parsing" ppt

... evaluate, test, re-solve, determine, investigate 10 nf-kappab, nf-kappa b, nfkappab, nf-kb 11 antiserum, antibody, monoclonal antibody, ab, an-tisera, mab 12 tnfalpha, tnf-alpha, il-6, tnf Table ... made in our model: for ex-ample, proper modeling of alterations requires joint generation of syntactic realizations for predicate-argument relations (Grenager and Manning, 2006; Lang and Lapata, ... MI USA. Nathanael Chambers and Dan Jurafsky 2009 Unsu-pervised learning of narrative schemas and their par-ticipants In Proc of the Annual Meeting of the As-sociation for Computational Linguistics

Ngày tải lên: 23/03/2014, 16:20

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Team Risk Management: A New Model for Customer- Supplier Relationships doc

Team Risk Management: A New Model for Customer- Supplier Relationships doc

... Integrated management • Making risk management an integral and vital part of project management • Adapting risk management methods and tools to a project’s infrastructure and culture Trang 12SEI ... administrators itmay mean ‘quality assurance.’ To safety professionals it is reducingaccidents and injuries [Kloman 90, p 20] Kloman Paraphrase of Rowe Risk management is a discipline for living ... 8].Kloman summarized the meaning of risk management in the context of a number of different disciplines in an article for Risk Analysis: What is risk management? To many social analysts, politicians,

Ngày tải lên: 23/03/2014, 23:21

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Synchronizing Gender Strategies: A Cooperative Model for Improving Reproductive Health and Transforming Gender Relations pot

Synchronizing Gender Strategies: A Cooperative Model for Improving Reproductive Health and Transforming Gender Relations pot

... and imbalance of power as a means of reaching health as well as gender- equity objectives. Gender-transformative approaches encourage critical awareness among men and women of gender roles and ... The Campaign promotes the idea that every man has a role to play, that each man can create a better, more equitable, and more just world The Campaign promotes this goal through a variety ... integration into new and rewarding territory: the adoption of gender synchronization as a practical approach that will make programs that challenge harmful gender norms—gender transformative

Ngày tải lên: 28/03/2014, 14:20

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Báo cáo " A numerical model for the simulation of wave dynamics in the surf zone and near coastal structures " pot

Báo cáo " A numerical model for the simulation of wave dynamics in the surf zone and near coastal structures " pot

... Trang 1A numerical model for the simulation of wave dynamics   in the surf zone and near coastal structures  Vu Thanh Ca*  Center for Marine and Ocean-Atmosphere Interaction Research, Vietnam ... observed  values  of  various  wave  characteristics,  it  can  be  remarked  that  the  numerical  model  can  simulate  wave  transformation  in  the  nearshore  region  with  an acceptable accuracy.  ... numerical  model  can  satisfactorily  simulate  the  wave  transformation,  including  wave  breaking,  wave  runup  on  the  beach,  and  turbulence  generated  by  wave  breaking  and  shear.  As 

Ngày tải lên: 28/03/2014, 15:20

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Báo cáo khoa học: A kinetic model for the burst phase of processive cellulases pptx

Báo cáo khoa học: A kinetic model for the burst phase of processive cellulases pptx

... Materials and methods All mathematical analysis and numerical fitting were performed using the software package Mathematica 7.0 (Wolfram Research, Inc Champaign, IL, USA) The substrate in the calorimetric ... n units are available for enzy- matic hydrolysis. This interpretation of obstacles and processivity is similar to that recently put forward by Jalak & Valjamae [14]. A kinetic treatment of ... nm 2 for Cel7A [34], we find an S 0 :E 0 area ratio (total available substrate area divided by monolayer coverage area of the whole enzyme popula- tion) which is an order of magnitude smaller

Ngày tải lên: 28/03/2014, 23:20

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Towards a better internet for children pdf

Towards a better internet for children pdf

... develop a generally valid approach to age-rating, which could be used across sectors and provide parents with understandable age categories; (4) Wider availability and use of parental controls: user-friendly ... in an age-appropriate way so they can safely manage personal information This includes giving the user control over their personal information (e.g that submitted during initial registration ... particular, young people are reluctant to seek (face-to-face) professional help, suggesting that alternative/online forms of support are important especially for girls; see Andersson, K., Osvaldsson,

Ngày tải lên: 29/03/2014, 20:20

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FED: FUZZY EVENT DETECTION MODEL FOR WIRELESS SENSOR NETWORKS pptx

FED: FUZZY EVENT DETECTION MODEL FOR WIRELESS SENSOR NETWORKS pptx

... Trang 1FED: F UZZY E VENT D ETECTION MODEL FOR WIRELESS SENSOR NETWORKS HadiTabatabaee Malazi1,Kamran Zamanifar1 and Stefan Dulman2 1 Department of Computer Eng., University of Isfahan, Iran ... sub-events, in a Boolean data type format, as an input parameter andcomputes a numeric value showing how likely the CE has happened DSWare aggregates the reported events alongthe path to the sink ... that Manjunatha addresses in[27] According to the proposed approach, sensors submit their sensed values to an aggregation point The meanof transmitted values are considered as aggregated value

Ngày tải lên: 30/03/2014, 16:20

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RBF Neurals Networks and a new algorithm for training RBF networks

RBF Neurals Networks and a new algorithm for training RBF networks

... Trang 11 Summary 2 Introduction about function regression 3 RBF Neurals Networks and a new algorithm for training RBF networks 4 Experiment 5 Conclusion Trang 21 SUMMARY Gaussian radial basis ... regression method, we create a new set of data with equally spaced nodes in a given web defined in the range of parameters of original unequally spaced nodes Each value of new equally spaced nodes is noise ... HDH-1phase algorithm with the input data is new equally spaced nodes (circles) and the reduction value of each node Trang 52.3 The approximately multivariable function problemApproximating multivariable

Ngày tải lên: 12/04/2014, 15:40

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Báo cáo hóa học: " Development of a mathematical model for predicting electrically elicited quadriceps femoris muscle forces during isovelocity knee joint motion" potx

Báo cáo hóa học: " Development of a mathematical model for predicting electrically elicited quadriceps femoris muscle forces during isovelocity knee joint motion" potx

... length A was found to vary in a parabolic manner and was modeled as A(θ) = a(40 - θ)2 + b(40 - θ) + A40, (11) where A40 is the value of A at 40° of knee flexion, and a and b are constants that need ... parameterizing and testing trains Force data in response to parameterizing trains Force data in response to parameterizing trains Force data in response to testing trains that were not used for model ... motor A40 N/ms scaling factor for force at 40° of knee flexion a N/ms-deg 2 scaling factor to account for force at each knee flexion angle b N/ms-deg scaling factor to account for force at each

Ngày tải lên: 19/06/2014, 08:20

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báo cáo hóa học: " A cost model for optimizing the take back phase of used product recovery" docx

báo cáo hóa học: " A cost model for optimizing the take back phase of used product recovery" docx

... the take back process and provide significant insights for analyzing and also managing the take back process. Model We consider three important aspects of take back in our model: the financial ... impractical. In this section we rationalize a simple model for mte without further empirical validation. Alternative models may be used based on empirical data. Ghoreishi et al. Journal of Remanufacturing ... RESEARCH Open Access A cost model for optimizing the take back phase of used product recovery Niloufar Ghoreishi 1* , Mark J Jakiela 1 and Ali Nekouzadeh 2 Abstract Taking back the end-of-life

Ngày tải lên: 21/06/2014, 02:20

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Báo cáo hóa học: " Research Article Experimental Characterization of a UWB Channel for Body Area Networks" potx

Báo cáo hóa học: " Research Article Experimental Characterization of a UWB Channel for Body Area Networks" potx

... 2004. [10] Q. Wang, T. Tayamachi, I. Kimura, and J. Wang, “An on- body channel model for UWB body area communications for various postures,” IEEE Transactions on Antennas and Propagation, vol. 57, ... channels with various TX and RX antennas placed near the human are characterized. The frequency- and distance- dependent characteristics of a UWB channel are analyzed in this paper, where an ... node, such as in a local data storage memory. Then when the patient goes to the hospital, the doctor can read these data through high-data- rate transmission and make a thorough diagnosis, as shown

Ngày tải lên: 21/06/2014, 07:20

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báo cáo hóa học:" Research Article A Formal Model for Performance and Energy Evaluation of Embedded Systems" pot

báo cáo hóa học:" Research Article A Formal Model for Performance and Energy Evaluation of Embedded Systems" pot

... estimation A tool, named PECES, was implemented for automatizing the method Additionally, a measuring platform, named AMALGHMA, was constructed for characterizing the platform and for comparing ... The AMALGHMA (Advanced Measurement Algorithms for Hardware Architectures) tool has been implemented for automating the measuring activities AMALGHMA adopts a set of statistical methods, such as ... model a real platform, namely, NXP LPC2106, and a theoretical multiprocessor platform The high level of abstraction of the proposed models allows for fast but accurate estimates Additionally, although

Ngày tải lên: 21/06/2014, 11:20

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báo cáo hóa học:" Research Article Towards Automation 2.0: A Neurocognitive Model for Environment Recognition, Decision-Making, and Action Execution" docx

báo cáo hóa học:" Research Article Towards Automation 2.0: A Neurocognitive Model for Environment Recognition, Decision-Making, and Action Execution" docx

... Lab situations as we use today for training systems are not available in the real world It is always an amalgamation of different types of inputs, where relevant information is embedded into a ... perceptual aspects of all modalities are merged An example would be to perceive the visual shape of a person, a voice, and a certain odour and conclude that all this information belongs to a particular ... Taking these concepts as a basis for the development of technical systems appears to be a very reasonable idea: animals and humans have the capability to perceive and (re-)act on their environment

Ngày tải lên: 21/06/2014, 11:20

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