3 trail apo2l and its receptors

Synthesis and biological investigation of pyrimido 1,2 a 1,3,5 triazine and its analogues 2

Synthesis and biological investigation of pyrimido 1,2 a 1,3,5 triazine and its analogues 2

... type-1 On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases Type II receptors phosphorylate and activate type I receptors which ... 1ouy,3new, 3fl4, 1w82 3.024 0.4324 11 Androgen receptor Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation ... TGF-beta receptor type-1 On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases It then bind and activate SMAD transcriptionalcomplex,

Ngày tải lên: 10/09/2015, 15:49

55 349 0
3 17 science and its uses (space and technology)

3 17 science and its uses (space and technology)

... technology tool Picture Credits Every effort has been made to secure permission and provide appropriate credit for photographic material The publisher deeply regrets any omission and pledges to correct ... 1860s The Pony Express used horses and riders to carry mail across the country This way, mail could be delivered between Missouri and California Many riders and horses followed a schedule to move ... used horses and buggies to travel Many people also used trains But these types of transportation were slow Trains and cars are very fast today Sometimes you see superfast trains and cars in movies

Ngày tải lên: 21/04/2017, 08:55

14 155 0
Expression of prosaposin and its receptors in the rat cerebellum after kainic acid injection

Expression of prosaposin and its receptors in the rat cerebellum after kainic acid injection

... for PS-AS3 on days 1 and 3 (b and c) were more intense, whereas the signals for PS-AS4 (e and f) were less intense, compared to the control rats without KA injection (a and d, respectively) ... hippocampus and cerebellum AS4 (Pro+0) signals in the Hippcampus (Hip) and choroid plexus (CP) increased following the KA injection (a and b) but decreased in the cerebellum (CB) (c and d) AS3 ... typesetting, and review of the resulting proof before it is published in its final form Please note that during the production process errors may be discovered which could affect the content, and all

Ngày tải lên: 24/11/2022, 17:51

37 3 0
New Concepts in Diabetes and Its Treatment - part 3 docx

New Concepts in Diabetes and Its Treatment - part 3 docx

... (whole grain) gums and mucilages form gels and are soluble (oats, fruits and legumes) Thefoods naturally rich in fibers are legumes, roots, tubers, whole-grain cereals,fruits and green leafy vegetables ... obese) diabetic patients Diet education is crucial and requiresthe participation of the patient and its family in the planning-diet process and in the implementation of the adequate strategies ... dietary therapy in diabetes are to reach and maintain ideal bodyweight (IBW), to maintain fasting and postprandial glycemic levels as close as possible to normal and to achieve optimal blood lipid

Ngày tải lên: 09/08/2014, 15:20

27 305 0
3 carbon isotope discrimination in roots and shoots of major weed species of southern u s  rice fields and its potential use for analysis of rice–weed root interactions

3 carbon isotope discrimination in roots and shoots of major weed species of southern u s rice fields and its potential use for analysis of rice–weed root interactions

... f and fs are the respective C fractions and M and Ms are the respective masses of the total sample and soil component (g) in the sample mixture; f1and f2are the respective C fractions and M1 and ... (i.e., the original f1 and R1values become f2 and R2, respectively, whereas the original f2 and R2 values become f1 and R1, respectively) The fsand f values and the Rsand R values are left unchanged ... f1, and fsare the respective C fractions, and M, M1, and Ms are the respective masses of the total sample, root component, and soil component (g) in the sample mixture Note that for simplicity and

Ngày tải lên: 04/09/2015, 07:24

15 377 0
Studies of vortex breakdown and its stability in a confined cylindrical container 3

Studies of vortex breakdown and its stability in a confined cylindrical container 3

... independent calculations in other studies and with experimental results Table 1 presents the values and locations of three local maxima and minima of ψ and η at H/R = 2.5 and Re = 2494 with constant rotating ... for the present study Assuming N+1 and M+1 are the number of grid points in the r and z direction, respectively, then Δr and Δz can be calculated as: 1 M R H and + = + 1 N 1 Δ so, 1 M 0,1, ... continuity equation and appropriate boundary and initial conditions A cylindrical container with radius R and height H is completely filled with an incompressible fluid of constant density ρ and kinematic

Ngày tải lên: 14/09/2015, 14:02

16 269 0
Mixed mode i II III fracture criterion and its application to cement mortar 3

Mixed mode i II III fracture criterion and its application to cement mortar 3

... specimen, and the provision of an appropriate test set-up and procedure The former would include the casting and de-moulding of the specimen, as well as the formation of its pre-crack and notch, ... preparation, its compactness, and the ease of setting up and loading The load was applied monotonically at a rate of 0.1mm/min, until failure took place in the specimen The applied force, and corresponding ... loading frame, in two halves, by bolting, and subjected to pure modes I and III, as well as mixed mode I–III, loading Two purpose-built couplings were fabricated, and connected each half of the loading

Ngày tải lên: 17/09/2015, 17:18

23 195 0
3 16 the sun and its planets (space and technology)

3 16 the sun and its planets (space and technology)

... Opener: Brand X Pictures; 1 (CL, T) Brand X Pictures; 2 Brand X Pictures; 3 Brand X Pictures; 6 (TL) Brand X Pictures; 9 (CR, B) Brand X Pictures; 15 (B) ©Roger Ressmeyer/Corbis. Scott Foresman/Dorling ... Opener: Brand X Pictures; 1 (CL, T) Brand X Pictures; 2 Brand X Pictures; 3 Brand X Pictures; 6 (TL) Brand X Pictures; 9 (CR, B) Brand X Pictures; 15 (B) ©Roger Ressmeyer/Corbis. Scott Foresman/Dorling ... system Picture Credits Every effort has been made to secure permission and provide appropriate credit for photographic material The publisher deeply regrets any omission and pledges to correct

Ngày tải lên: 21/04/2017, 08:54

10 151 0
Effect of organic, inorganic and integrated nutrient sources on the yield and its attributes of two Basmati rice varieties Viz Type-3 and taraori grown in Tarai regions of Uttarakhand India

Effect of organic, inorganic and integrated nutrient sources on the yield and its attributes of two Basmati rice varieties Viz Type-3 and taraori grown in Tarai regions of Uttarakhand India

... cultivated land and water resources and particular socio-economic conditions Over exploitation of vegetation and soil resources and adoption of inappropriate farming systems have resulted in land degradation ... Organic, Inorganic and Integrated Nutrient Sources on the Yield and Its Attributes of Two Basmati Rice Varieties viz Type-3 and Taraori Grown in Tarai Regions of Uttarakhand India Dipti Bisarya ... methods and irrigation regimes Therefore with this concept and the benefits of organic fertilizers in mind the present investigation was carried out to understand the effect of different organic and

Ngày tải lên: 09/07/2020, 01:15

16 12 0
Molecular evidence of IGFBP-3 dependent and independent VD3 action and its nonlinear response on IGFBP-3 induction in prostate cancer cells

Molecular evidence of IGFBP-3 dependent and independent VD3 action and its nonlinear response on IGFBP-3 induction in prostate cancer cells

... actinomycin D and cy-cloheximide, which are transcriptional inhibitor and protein synthesis inhibitor, respectively, were added with VD3 or DHT/VD3, and behavior of IGFBP-3 protein and its mRNA was ... pattern of IGFBPs and their efficacy on the cell growth in-hibition would be required in depth understanding of the VD3 and DHT treatment in combination with anticancer drugs and its molecular mechanisms ... pre- and post-treatment serum were 0.24 nM and less than 0.01 nM (limit of de-tection), respectively The concentrations of total vita-min D in the pre- and post-treatment serum were 82.9 and 80.6

Ngày tải lên: 22/09/2020, 23:17

13 7 0
Plant organelle RNA editing and its specificity factors: Enhancements of analyses and new database features in PREPACT 3.0

Plant organelle RNA editing and its specificity factors: Enhancements of analyses and new database features in PREPACT 3.0

... AccessPlant organelle RNA editing and its specificity factors: enhancements of analyses and new database features in PREPACT 3.0 Henning Lenz1,2, Anke Hein1and Volker Knoop1* Abstract Background: ... Predicting and analyzing RNA editing, which ranges from only few sites in some species to thousands in other taxa, is bioinformatically demanding Results: Here, we present major enhancements and extensions ... thousands, such as in the lycophytes [35–37] The PREPACT WWW service developed in our group [38,39] aimed for (i) standardizing RNA editing annota-tion and nomenclature, (ii) making the vast and

Ngày tải lên: 25/11/2020, 14:05

18 10 0
Empirical Modeling and Its Applications. Chapter 3: Least Squares Method and Empirical Modeling: A Case Study in a Mexican Manufacturing Firm

Empirical Modeling and Its Applications. Chapter 3: Least Squares Method and Empirical Modeling: A Case Study in a Mexican Manufacturing Firm

... types of models (e.g., linear, quadratic, and exponential) that could best fit the relationship between TC and its determinants [8] After different tests and analyses, it was found that a linear ... sometimes, impartiality and scientific rigor in the analysis of data and results might be difficult to achieve Consequently, inconsistencies between the real-life problem and the model proposed ... shipment Evidently, more accurate cost estimates can result in better budgeting decisions and its associated benefits To accomplish their objective, MF’s top management made the decision to conduct

Ngày tải lên: 08/02/2021, 07:45

15 10 0
Big Data on Real-World Applications. Chapter 3: Introduction to Big Data in Education and Its Contribution to the Quality Improvement Processes

Big Data on Real-World Applications. Chapter 3: Introduction to Big Data in Education and Its Contribution to the Quality Improvement Processes

... analysis and reporting of data about learners and their contexts, for purposes of understanding and optimising learning and the environments in which it occurs” [20] and affects actions and operations ... devices and apparatuses, teleconference and remote access systems, educational platforms and services and other that students, teachers, academic faculty, evaluation specialists, researchers and ... improvement science and its impact on different processes in education such as the learning, educational and academic processes and (b) as a result of the practical application and realization of

Ngày tải lên: 08/02/2021, 07:45

19 14 0
Chapter 3 : ELASTICITY AND ITS APPLICATION  PRINCIPLES OF MICROECONOMICS

Chapter 3 : ELASTICITY AND ITS APPLICATION PRINCIPLES OF MICROECONOMICS

... if A demand is inelastic and supply is elastic B supply is inelastic and demand is elastic C both supply and demand are elastic D both supply and demand are inelastic 51 Assume the demand for ... decline? A price rises and supply is elastic B price falls and demand is elastic C price rises and demand is inelastic D price rises and demand is elastic 13 Technological improvements in agriculture ... points further up and to the left along the demand curve B at points further down and to the right along the demand curve C when the demand curve becomes steeper D when the demand curve is vertical

Ngày tải lên: 21/04/2021, 13:29

12 123 0
Synthesis and structural properties of N -3,4-(dichlorophenyl)-3-oxo-3- phenyl-2-(phenylcarbonyl)propanamide and its Cu(II) complex

Synthesis and structural properties of N -3,4-(dichlorophenyl)-3-oxo-3- phenyl-2-(phenylcarbonyl)propanamide and its Cu(II) complex

... between molecular structure and the physiochemical property relationship of molecules such as biomolecules and drugs,20−26 and to understand sites for electrophilic and nucleophilic reactions ... chloroform and methanol mixture The route for the synthesis of compounds 3 and 4 is shown in the Scheme The characterization of 3 and 4 was carried out by elemental analysis, UV-Vis, IR, 1H, APT NMR, and ... 131.37, and 134.49 and the second one, C–H carbon, among three carbonyl carbons at 64.88 ppm In summary, 1H and APT NMR spectra of compound 3 provided the characteristic chemical shifts and confirmed

Ngày tải lên: 12/01/2022, 23:55

17 6 0
Hydraulic modeling of open channel flows over an arbitrary 3-d surface and its applications in amenity hydraulic engineering

Hydraulic modeling of open channel flows over an arbitrary 3-d surface and its applications in amenity hydraulic engineering

... the following published and/ or accepted journal and conference papers: Anh T N and Hosoda T.: Depth-Averaged model of open channel flows over an arbitrary 3D surface and its applications to analysis ... channel, flow in meandering channel, and flow in Parshall flume with supercritical outflow was satisfactory Zhou and Goodwill (1997) presented a depth-averaged model and compared its predictions ... and Vreugdenhill, C B 1973 Calculations of two-dimensional horizontal flow Rep S163, Part 1, Delft Hydraulics Laboratory, Delft, The Netherlands Steffler M P and Jin Y C 1993 Depth averaged and...

Ngày tải lên: 06/11/2012, 10:35

127 599 0
Báo cáo khoa học: Isoquinoline-1,3,4-trione and its derivatives attenuate b-amyloid-induced apoptosis of neuronal cells pdf

Báo cáo khoa học: Isoquinoline-1,3,4-trione and its derivatives attenuate b-amyloid-induced apoptosis of neuronal cells pdf

... isoquinoline-1,3,4-trione and its derivatives as selective, irreversible, slow-binding, pan-caspase inhibitors This compound and its derivatives protected PC12 cells and primary cortical neuronal ... caspase solutions were 90% pure, and 15% SDS ⁄ PAGE revealed they contained 20 kDa and 10 kDa subunits, which is consistent with previous reports on their autocleavage and activation Selectivity of ... caspase-3 have been reported [21–24] Isatin sulfonamide and its analogues are potent and selective inhibitors of apoptosis of chondrocytes and mouse bone marrow neutrophils in cell-based models...

Ngày tải lên: 07/03/2014, 11:20

11 389 0
Báo cáo khoa học: "The early responses of VEGF and its receptors during acute lung injury: implication of VEGF in alveolar epithelial cell survival" ppt

Báo cáo khoa học: "The early responses of VEGF and its receptors during acute lung injury: implication of VEGF in alveolar epithelial cell survival" ppt

... the mRNA levels of VEGF and its receptors The results are also not statistically significant (data not shown) Correlations of VEGF and its receptors with lung injury and epithelial cell death ... surrounding cells and tissues may mask the changes of VEGF, or its receptors Conclusion Our results suggest that significant and dynamic changes of expression of VEGF and its receptors take place ... scoring and supervised pathological studies TKW and SK provided assistance in physiological studies and data interpretation ML conceived the study, and participated in its design and coordination and...

Ngày tải lên: 13/08/2014, 03:20

13 291 0
Synthesis and biological investigation of pyrimido,1,2 a ,1,3,5,triazine and its analogues 1

Synthesis and biological investigation of pyrimido,1,2 a ,1,3,5,triazine and its analogues 1

... Mahajan and coworkers13 in 2008 contained only 16 references and have missed out many valuable references 1.1 Literature review on the synthesis of pyrimido[1,2-a][1,3,5]-triazines and its fused ... derivatives 101a against Microsporum canis and average affinity of 101b for serotoninergic 5-HT1A and 5-HT2B receptors was also published by Lucry and coworkers53 C2H5 O O C2H5 N C2H5 N H Cl ... atoms and its applicability to address critical questions in a wide range of disciplines, the Nobel Prize was awarded to John Pople and Walter Kohn in 1998 Comprehensive review on methodology and...

Ngày tải lên: 10/09/2015, 15:49

143 421 0
Tài liệu Báo cáo khoa học: Biochemical characterization of human 3-methylglutaconyl-CoA hydratase and its role in leucine metabolism docx

Tài liệu Báo cáo khoa học: Biochemical characterization of human 3-methylglutaconyl-CoA hydratase and its role in leucine metabolism docx

... seems, that the fronting, the shoulder and the tailing is due to acetyl-CoA and not due to any other compound (B) The peaks 3, 4, and were isolated by HPLC and used as substrates for AUH The AUH ... for its synthesis and developing a new assay In addition, a mutant form of AUH (A240V) derived from an MGA1 patient was tested using 3-MG-CoA Results Overexpression of AUH in Escherichia coli and ... proteolysis and the resulting proteins AUHp40 and AUHp30 were again purified by chromatography Thus, four different pure fractions of AUH could be generated: MBP-AUHp40, AUHp40, MBP-AUHp32 and AUHp32...

Ngày tải lên: 19/02/2014, 07:20

11 625 0
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