2 regional therapy techniques plus extracorporeal drug removal systems

... smoking history Chemotherapy was done before radiation in 21 patients (62%), and concurrent chemoradiotherapy was done in 15 patients (44%) The used regimens for concurrent chemotherapy were combinations ... 63:324-333 Marino P, Preatoni A, Cantoni A: Randomized trials of radiotherapy alone versus combined chemotherapy and radiotherapy in stages IIIa and IIIb non-small cell lung cancer a meta-analysis ... Martin M, Douillar JY, Tarayre M, Lacombe-Terrier MJ, Laplanche A: Radiotherapy alone versus combined chemotherapy and radiotherapy in unresectable non-small cell lung carcinoma Lung Cancer 1994,...

Ngày tải lên: 09/08/2014, 10:20

... radiotherapy, surgery only, radiotherapy only, and neither surgery nor radiotherapy) (p < 0.01) The percentage of cases surviving five years by treatment modality was: 73% for surgery and radiotherapy, ... following treatment groups was queried: both surgery and radiotherapy, surgery only, radiotherapy only, neither surgery nor radiotherapy Staging in the SEER data is based on classification criteria ... Estimate (months) Both Surgery and Radiotherapy 296 (61.0) 109 187 150 Surgery Only 105 (21.7) 41 64 169 Radiotherapy Only 53 (10.9) 30 23 39 Neither Surgery nor Radiotherapy 31 (6.4) 18 13 10 *26 cases...

Ngày tải lên: 09/08/2014, 09:20

... survivals in radiotherapy and no-radiotherapy group Radiotherapy Group Radiotherapy n = 66 NoRadiotherapy n = 24 n % n % 1.5 P Local-regional recurrence Chest wall alone No Radiotherapy Peripheral ... Failure al e-Free Sur rvival Rat (%) te Local Failure-Free Survival Radiotherapy Radiotherapy No Radiotherapy No Radiotherapy Long –rank p value=0.038 (78.152-220.361 CI 95%) Long-rank P value ... 5-fluorouracil) adjuvant chemotherapy were administered to 89 of patients (99%) and 66 patients (73%) received adjuvant endocrine therapy for years One patient only received hormonal therapy Sixty-six patients...

Ngày tải lên: 09/08/2014, 09:20

... regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any change in indications and dosage and for ... Radiation Therapy of Prostate Cancer – Techniques, Outcomes, Pitfalls 145 Adjuvant Radiotherapy following Radical Prostatectomy Wiegel, T (Berlin) 152 Morbidity following Radiation Therapy Three-Dimensional ... planned treatment techniques The techniques which have been recently developed in this context are called intensity-modulated radiotherapy (IMRT) (see below) Modern Conformal Treatment Techniques As...

Ngày tải lên: 28/03/2014, 11:20

... c3DCRT: classic tridimensional conformal radiotherapy; f3DCRT: fitting tridimensional conformal radiotherapy, IMRT: intensity modulated radiation therapy; D95: minimal dose to 95% of the volume; ... conventional tridimensional conformal radiotherapy (blue line) f3DCRT: modificated tridimensional conformal radiotherapy (pink line) IMRT: intensity modulated radiation therapy (green line) Table Homogeneity ... c3DCRT: classic tridimensional conformal radiotherapy; f3DCRT: fitting tridimensional conformal radiotherapy, IMRT: intensity modulated radiation therapy; GTV: gross tumor volume; CTV: clinical...

Ngày tải lên: 09/08/2014, 08:22

... image modalities is widely used in radiotherapy for delineating the region of interests[27] As the registration algorithms in the commercial treatment planning systems generally use rigid body transformations, ... image guided radiation therapy need for plan adaptation? J Appl Clin Med Phys 2009, 10(3):2883 Thomas SJ: Relative electron density calibration of CT scanners for radiotherapy treatment planning ... Chao KK, Wloch J, Yan D: ImageGuided Radiotherapy Via Daily Online Cone-Beam CT Substantially Reduces Margin Requirements for Stereotactic Lung Radiotherapy Int J Radiat Oncol Biol Phys 2008,...

Ngày tải lên: 09/08/2014, 08:23

... for comparing tomotherapy with coplanar IMRT *: The p value is < 0.05 for comparing tomotherapy with noncoplanar IMRT [40] In the mean time, the noncoplanar IMRT and tomotherapy techniques reduced ... radiation therapy could be an effective choice for selected HCC patients with PVT [20] Rotational IMRT modalities, including helical tomotherapy (HT) [23], VMAT (Volumetric intensity modulated arc therapy) ... helical tomotherapy techniques All targets and OARs were delineated on Eclipse V7.3.10 planning system (Varian Medical System, Palo Alto, CA, USA) and then transferred to Helical Hi-Art Tomotherapy...

Ngày tải lên: 09/08/2014, 08:23

... tumor dose, both compared to conventional techniques and 3D conformal therapy There are several limitations to the current study First, we compared techniques in only three patients In order ... patients after radiotherapy J Clin Oncol 2008, 26:5119-5125 Eisbruch A, Levendag PC, Feng FY, et al: Can IMRT or brachytherapy reduce dysphagia associated with chemoradiotherapy of head and neck ... PTV margins as low as 0.3 cm have been utilized with conformal techniques We found in this study that, while IMRT and 3D conformal techniques were similar in terms of target coverage and the “clinically...

Ngày tải lên: 09/08/2014, 09:20

... JF, Gonzalez DG, Peiffert D, van Glabbeke M, Pierart M: Concomitant radiotherapy and chemotherapy is superior to radiotherapy alone in the treatment of locally advanced anal cancer: results of ... intensitymodulated radiation therapy (IMRT) and chemotherapy Radiother Oncol 2009, 93:298-301 10 Pepek JMWCG, Clough RW, Wu QJ, Yoo S, Czito BG: Intensity Modulated Radiation Therapy (IMRT) for Anal ... modulated arc therapy for delivery of prostate radiotherapy: comparison with intensity-modulated radiotherapy and three-dimensional conformal radiotherapy Int J Radiat Oncol Biol Phys 2008, 72:996-1001...

Ngày tải lên: 09/08/2014, 09:20

... radiotherapy techniques using AP/PA fields and 6-15 MV photon beams with partial OAR shielding is applied but this has major dosimetric limitations [6,35] The advent of newer radiation techniques ... complete surgical remission after induction chemotherapy: a randomized, controlled, clinical trial comparing whole abdominal radiotherapy, chemotherapy, and no further treatment Int J Gynecol ... delivery of prostate radiotherapy Comparison with intensity modulated Page of 24 25 26 27 28 29 30 31 32 33 34 35 36 37 radiotherapy and three-dimensional conformal radiotherapy Int J Radiat Oncol...

Ngày tải lên: 09/08/2014, 09:20

... Therapeutic Radiation Oncology; CRT: Conformal Radiation Therapy; CT: Chemotherapy; CTV: Clinical Target Volume; EORTC: European Organization on Radiation Therapy Consortium; GI: Gastrointestinal; GU: Genitourinary; ... Mensurements; IMRT: Intensity Modulated Radiation Therapy; OAR: Organ at Risk; PTV: Planning Target Volume; RT: Radiation Therapy; RTOG: Radiation Therapy Oncology Group; SIB: Simultaneous Integrated ... radiotherapy versus conventional techniques for treatment of cervical cancer Int J Radiat Oncol Biol Phys 2008, 71:1504-1510 15 Lujan AE, Mundt AJ, Yamada SD, et al: Intensity-modulated radiotherapy...

Ngày tải lên: 09/08/2014, 09:20

... fewer sites of metastases in which all sites were treated with aggressive local therapy with possible systemic therapy Otherwise, patients were classified as having extensive metastatic disease ... year OS rate of 39% [30] The argument for using ablative local therapy for isolated metastases is strengthened if effective systemic therapy is available to complement it [31] And in recent years, ... from a general reduction in their systemic disease burden, whether achieved by systemic therapy or local therapy Indeed, for the case of RCC in particular, two independent phase III studies indicate...

Ngày tải lên: 09/08/2014, 09:20

... compared to postoperative therapy [4] The recently published NSABP R-03 trial demonstrated a significant improvement in 5-year disease-free survival with preoperative therapy, and a trend toward ... intensity-modulated radiation therapy (IMRT) Wholepelvis IMRT has been applied to gynecologic malignancy, with less toxicity than traditional 3D conformal radiation therapy (3DCRT)[13] In anal ... planning target volume; IMRT = intensity modulated radiation therapy; 3FBB = field belly board; 3DCRT = dimensional conformal radiation therapy; HI = homogeneity index; CI = conformality index;...

Ngày tải lên: 09/08/2014, 09:20

... reirradiation Brachytherapy Brachytherapy has achieved good local control in selected patients Hepel reported of experiences in 30 patients reirradiated by high-dose-rate brachytherapy [22] All ... [18] Patients were treated with multiple 2-week cycles of days of chemoradiotherapy, followed by a 9-day break Radiotherapy was administered either daily or twice daily (bid), with a mean total ... those observed in RTOG 96-10 Accordingly, to compare reirradiation and concurrent chemotherapy with chemotherapy alone in inoperable, previously irradiated, locally recurrent or second primary...

Ngày tải lên: 09/08/2014, 09:21

... after completion of treatment No patients received neoadjuvant chemotherapy Thirteen patients (24.5%) received adjuvant chemotherapy after surgery Serum samples were stored at -20°C until analysis ... concentrations in serum drawn at follow-up in patients receiving adjuvant chemotherapy compared to patients not receiving adjuvant chemotherapy (data not shown) Association between TATI in tissue and serum ... Trial: long lasting benefits from radiotherapy on survival and local recurrence rate J Clin Oncol 2005, 23:5644-5650 Improved survival with preoperative radiotherapy in resectable rectal cancer...

Ngày tải lên: 09/08/2014, 09:21

... radiotherapy; FU = follow-up; Tox = toxicity score used; Ref = reference; 3D = three-dimensional conformal radiation therapy; IMRT = intensity modulated radiation therapy; RTOG = Radiation Therapy ... Lukka HR, Levine M: Randomized trial comparing iridium implant plus external-beam radiation therapy with external-beam radiation therapy alone in node-negative locally advanced cancer of the prostate ... patient was counted as a single event; † During therapy and until months after completion; ‡ maximal late toxicity > months after completion of therapy; § Incidence of late toxicity at last follow-up...

Ngày tải lên: 09/08/2014, 09:22

... techniques such as tomotherapy, intensity modulated arc therapies or volumetric modulated arc therapies have been described [1,2] As results of treatments of lung cancer patients with these techniques ... C: Clinical implementation of intensity-modulated arc therapy Int J Radiat Oncol Biol Phys 2002, 53:453-463 Otto K: Volumetric modulated arc therapy: IMRT in a single gantry arc Med Phys 2008, ... Primary tumor size-Radiation dose-related accelerated, twice daily radiotherapy by target splitting, preceded by two cycles of chemotherapy – first results of a prospective study Strahlenther Onkol...

Ngày tải lên: 09/08/2014, 10:20

... the recent, more sophisticated RT techniques, including intensitymodulated radiotherapy (IMRT), image guided radiotherapy (IGRT), and especially helical tomotherapy (HT), are promising However, ... this aggressive procedure [5,6] In this context, radiation therapy (RT) as the sole treatment in the presence or absence of concurrent chemotherapy may be a good alternative in suitable patient population ... tomography-computed tomography; PTV1 = planning target volume (defined as CTV plus a 1-cm margin); PTV2 = planning target volume (defined as GTV plus a 1-cm margin) increament was due to additional involved...

Ngày tải lên: 09/08/2014, 10:20

... fractionation radiotherapy schedule, surgery, chemotherapy and RPA class, showed in table The supportive care (oral prednisone) and neurological status was not evaluated Chemotherapy was Results ... supportive care (oral predinisone) plus radiotherapy versus supportive care alone or WBRT alone versus supportive care However, Horton et al [19] compared WBRT plus supportive care (oral prednisone) ... be made to incorporate multimodality approaches including surgery, radiosurgery, chemotherapy, and radiotherapy sensitizers to improve survival In this study, patients with multiple brain metastases...

Ngày tải lên: 09/08/2014, 10:21