2 narrative synthesis and systematic reviews

... binding and selective alkylation leading to a depletion of mtDNA in intact cells (Fig 1) Here we report the synthesis and characterization of a novel mitochondria-targeted alkylating reagent and ... liver mitochondria (40 mg protein) and incubated with 500 lM mitoDC-81 for h and then cut with ClaI (C and D) DNA was separated by electrophoresis on an agarose gel and the ethidium bromide fluorescence ... bromide gel and the fluorescence recorded (A and C) The DNA was then transferred to a nylon membrane and TPP moieties covalently attached to the DNA were visualized using anti-TPP serum (B and D) The...

Ngày tải lên: 20/02/2014, 11:20

... Cruise Take-off and Landing Fuel Materials Themal Protection Certification Base 300 passengers at 175 lbs and 40 lbs of baggage each pilots and 10 flight attendants at 175 lbs and 30 lbs of baggage ... Acceptable system cost Safety and reliability Reliability and survivability Long service life System complexity and mechanical design Damage tolerance Military standards Must be certifiable (FAA, ... reliability and maintainability, subsystems properties and performance, and others Some of these are illustrated in the table below, based on a Boeing chart Transport Aircraft Design Objectives and Constraints...

Ngày tải lên: 08/08/2014, 11:21

... solves the three-position and four-position linkage synthesis problems The computer programs provided with this text also allow you to three-position analytical synthesis and general linkage design ... chapter discusses graphical dimensional synthesis of linkages in detail Chapter presents methods of analytical linkage synthesis, and Chapter presents cam synthesis 3.2 * Available from Knowledge ... angle is then between links and and is zero at that position But a force applied to link as the input link will move it The transmission angle is now between links and and is 45 degrees * Alt,...

Ngày tải lên: 08/08/2014, 12:23

... review,' and 'rapid and systematic reviews. ' These rapid reviews vary in the length of time taken to conduct literature reviews and synthesis, with timeframes ranging from one to nine months Some reviews ... of rapid review approaches and systematic reviews, in a study of reporting characteristics of systematic reviews, Moher et al found that the quality of systematic reviews themselves are inconsistent, ... limited time and resources to conduct full systematic reviews [4] Systematic reviews typically take a minimum of six months to one year to complete To address requests for literature reviews in...

Ngày tải lên: 10/08/2014, 10:23

... policymakers and managers to use systematic reviews in decision making Three of the articles report data from one intervention that distributed five systematic reviews to health policymakers and managers ... the study concept and design LP and SES constructed and refined the search strategy SES and LP acquired the data Analysis and interpretation of the data was completed by LP, KM, and SES Drafting ... appraise, and apply (see Additional File 1) The grey literature was searched after identifying key websites and search engines, such as Google and Intute Reference lists of all papers and relevant reviews...

Ngày tải lên: 10/08/2014, 10:23

... 84, and 87 97 X List of Schemes 2.1A: Synthesis of A-Ring Analogs - 14 39 2.1B: Synthesis of A-Ring Analogs 15 - 17 40 2.2A: Synthesis of Thioamide 18 41 2.2B: Synthesis of Quinazolinones 19 and ... auxiliary based method of synthesis Preliminary success led to a more thorough exploration of the scope and limitations of this methodology, and ultimately to the synthesis of the R and S enantiomers ... and 20 41 2.2C: Synthesis of Quinoxaline 21 42 3.1A: Synthesis of C-Ring Analogs 22 – 29 54 3.1B: Synthesis of C-Ring Analog 30 54 3.1C: Synthesis of C-Ring Analog 31 55 3.2A: Synthesis of D-Ring...

Ngày tải lên: 13/11/2014, 11:20

... (DMSO-d6) using Tetramethylsilane as an internal standard The mass spectra were recorded on a Micromass Q-TOF and Shimadzu LC–MS 2010A Mass spectrometer and CHN elemental analysis was performed at Perkin ... (D’Armour and Smith, 1941) method using Swiss albino mice In this method, heat is used as a source of pain Overnight fasted healthy and adult male Swiss albino mice weighing between 20 g and 25 ... h, h, h, h and h after treatment of test compounds by digital analgesiometer (INCO, Ambala, India) The drug pentazocine (3.9 mg/kg, i.p.) was used as standard drug for comparison and test groups...

Ngày tải lên: 02/09/2015, 13:45

... current and previous friends in Singapore, Anand, Durga, Deva, Gopal, Dr Vasu, Venu and many more for their help and association I want to pay my deep regards and gratitude to all my teachers and ... CPs and its photo reactivity which are synthesized from using Cd2+, 1,4-benzenedicarboxylate as linker and 4spy and its derivatives as photoreactive ligand Among these, the CP with 4spy ligand ... C-Hπ and C-HX in solid state and their properties in solid state and their role in the design and synthesis of organic solids during his studies in the late 80’s and early 90’s showed the promising...

Ngày tải lên: 09/09/2015, 11:15

... 2nll 2.973 0.515 Androgen receptor Steroid hormone receptors are ligandactivated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation ... 3.348 0.308 49 Androgen receptor Steroid hormone receptors are ligandactivated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation ... C3 Catalyzes the conversion of aldehydes and ketones to alcohols Catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ) and the oxidation of 9-alpha,11-beta- PGF2...

Ngày tải lên: 10/09/2015, 15:49

... only 16 references and have missed out many valuable references 1.1 Literature review on the synthesis of pyrimido[1,2-a][1,3,5]-triazines and its fused analogues Ziegler and Noelken14 were the ... pyrimido[1,2-a][1,3,5]triazindione 110 1.1.3 Synthesis by concurrent formation of both the pyrimidine and triazine ring Two bond formation with concurrent cyclization using anthranillate and amidine as pyrimidine and triazine ... Sawada and coworkers33 addressed the question of regioselectivity of the reaction using X-ray and 13 C NMR analysis They confirmed that 2H- pyrimido[1,2-a][1,3,5]triazin-2,4,8(3H,9H)-trione 45 (and...

Ngày tải lên: 10/09/2015, 15:49

... from 3a and generated by breaking H-bond of Oa···Hb (1A & 1B), Hb···Oc (2A & 2B), Oc···Hd (3A & 3B) and Hd···Oe (4A & 4B), and by breaking H-bonds of both Oa···Hb and Hb···Oc (5A & 5B), and both ... between axis ac and plane of the molecules, all the other three dimers (2a, 2c and 2d) are stacked along axis a with angles of 90º, 53º and 70º, respectively, between axis a and plane of the ... supramolecular structures with non-collapsible pores and channels capable of conducting ions and small molecules.10m 2.2 Result and Discussion 2.2.1 Synthesis of Oligoamides OC 8H 17 R2 O N H O 8R...

Ngày tải lên: 10/09/2015, 15:49

... from to V and to -2 V at room temperature while the corresponding current was detected 61 Chapter 2.3 Synthesis of metal thiobenzoate precursors and metal sulfide nanoparticles 2.3.1 Synthesis ... standardize the concentration of Hg(NO3)2 using: bromophenol blue and diphenylcarbazone as indicators 2.2 Characterization Techniques 2.2.1 Elemental analysis (EA) The microanalysis for C, H and ... standardized as follows: 3.0 grams of Hg(NO3)2 (AR, BDH) was weight accurately and dissolved in 500 mL of 0.01 M HNO3 After filtering, the solution was made up to 1750 mL with 0.01 M HNO3 and...

Ngày tải lên: 12/09/2015, 08:16

... properties – can be widely and easily tuned by adjusting the crystal’s size and shape The combination of size- and shape-dependent physical properties and ease of fabrication and processing makes NCs ... are good candidates for synthesizing photonic crystals 6.4 Synthesis and Methodology All the reactions were performed under the argon atmosphere using standard Shlenk techniques The synthesis ... books and reviews. 36-41 Reaction conditions that influence the mixing process, such as rate of reactant addition and stirring rate, must be considered relevant to product size, morphology, and...

Ngày tải lên: 14/09/2015, 10:19

... that Ge has a narrower bandgap and a similar electron affinity as Si which provides a higher confinement barrier for the retention mode and a smaller barrier for the program and erase modes for the ... quality and thus reduce its thermal stability - 110 - Chapter Figure 5.7: Results & Discussions II Raman spectrum for Sample C annealed at 700 and 800°C in N2 for 15 and 60 minutes Figures 5.8 (a) and ... Kosinski and K W West, “Precipitation of group V elements and Ge in SiO2 and their drift in a temperature gradient,” Appl Phys Lett., vol 53, pp 1178 -1180, 1988 [21] D.C Paine, C Caragianis and A...

Ngày tải lên: 14/09/2015, 14:04

... organic groups and n = 6, 8, 10 or higher Structures of silsesquioxanes include random, ladder, cage and partial cage structures (Figure 4.1) and are generally produced by the hydrolysis and condensation ... containing barium, strontium and zirconium These fillers increase strength and modulus of elasticity and reduce the polymerization shrinkage, the coefficient of thermal expansion and water sorption.37 ... substantial tensile strength and modulus, acceptable water sorption and solubility, and a slight expansion Increased concentrations of the SOC produced greater expansion and slightly stronger polymers,...

Ngày tải lên: 14/09/2015, 18:35

... dissolved in chloroform and the absorbance and emission properties were studied The polymers, C6PPPOH, C12PPPOH and C18PPPOH, showed a strong absorption (λabs = 335, 345 and 331 nm) and intense blue ... 1H-, 13 C-NMR and elemental analysis to confirm product The details of synthesis and characterization are given in the experimental chapter (chapter 6) The polymers C6PPPOH, C12PPPOH and C18PPPOH ... CH3 CH3 CH3 65 LS and LB Film Formation of Planar Amphiphilic poly(p-phenylene)s Figure 2.1 Molecular structure of CnPPPOH polymers 2.2 Results and discussion 2.2.1 Synthesis and characterization...

Ngày tải lên: 14/09/2015, 18:38

... gave one major band and two minor bands Band gave orange crystals of Cp*IrOs2(CO)9, 8, (trace amount) identified by comparison with the X-ray, IR, 1H NMR and MS data reported [25] Band gave unreacted ... either a Cp or Cp* ligand, along with the isolated yields and 1H NMR chemical shifts 29 Table 2.1 Known Cp and Cp* containing Ru3Ir and Ru3Rh tetranuclear clusters Cluster and yield reported Cp*IrRu3(μ-H)4(CO)9 ... the Ru3Ir and Os3Ir mixed metal framework, only a handful are on clusters containing a Cp or Cp* ligand Table 2.1 summarizes the known tetranuclear Ru3Ir and Ru3Rh, as well as Os3Ir and Os3Rh...

Ngày tải lên: 16/09/2015, 08:32

... region and a broad peak at 2θ = 7.52 and 20.2°, from which a d spacing of 11.8 and 4.4 Å is derived For P02 and P04, the diffraction patterns only exhibit one broad peak at 2θ = 20.1o and 20.2 o, and ... mol), and 100 ml absolute ethanol were added to a 250 ml roundbottom flask, and purged with N2 for 20 0.9 g NaOH was added to the mixture and purged with N2 for another 20 min, heated to 60 °C and ... of 35.9Å, 30.6 Å and 18.0 Å are derived It also offers a sharp reflection in the middle angle region and a broad halo at 2θ = 7.42 and 19.9 °, from which d spacings of 11.9 Å and 4.5 Å are derived...

Ngày tải lên: 16/09/2015, 17:11

... all monomers is shown in Figure 2.1 Bands at around 3110 cm-1 and 3050 cm-1 were results of C-H stretching for H (Hs at positions and on the thiophene ring) and H (H on position of the thiophene ... absorption bands at 1254 (-CH2- deformation), 645 and 556 cm-1 (C-Br stretching) [17] In addition, the polymers depicted bands at 3052 cm-1 which are ascribable to thienylene C-H stretching and 829 ... in ether, and the ethereal extract was filtered from , -dimethoxyphenoxy alkane, washed with dilute sodium hydroxide and water, dried and distilled, giving recovered , -dibromobutane and -(p-...

Ngày tải lên: 16/09/2015, 17:11