1 600 kda 1 hour post lipopolysaccharide infusion
Báo cáo y học: "Mechanical ventilation using non-injurious ventilation settings causes lung injury in the absence of pre-existing lung injury in healthy mice" pdf
... (mmol/l) 21. 4 ( 21. 1 to 24 .1) 16 .6 (15 .2 to 18 .9) 28.0 (26 .1 to 30.0) 14 .6 (13 .3 to 15 .6) 24.9 ( 21. 3 to 25.5) BE -1. 3 (-2.3 to -0.5) -11 .7 ( -12 .5 to -10 .2) 4 .1 (1. 3 to 6.0) -12 .8 ( -13 .4 to -10 .1) 2.3 ... 16 1 (50) PaO2 (mmHg) HCO3- (mmol/l) 21. 1 (17 .9 to 24 .1) 14 .4 (12 .9 to 15 .2) 25.2 (23.6 to 25.9) 13 .5 (12 .1 to 14 .7) 24.5 (22.7 to 25.4) BE -3.9 (-6.2 to -2.5) -12 .3 ( -13 .6 to -11 .8) 0 .15 ( -1. 1 ... 7 .11 (0.07)‡ 7.37 (0.08) 39.3 ( 31. 6 to 51. 3) 35.7 ( 31. 1 to 39.5) 41. 2 (35.3 to 43.6) 40.8 (37.0 to 55.6) 44.3 (36 .1 to 51. 7) 19 3 (36) PaCO2 (mmHg) NaCl 7.34 (0.05) PH NaHCO3 16 8 (48) 17 3 ( 51) 16 1...
Ngày tải lên: 13/08/2014, 11:23
Báo cáo sinh học: "Genetic parameters for lactation traits of milking ewes: protein content and composition, fat, somatic cells and individual laboratory cheese yield" ppt
... ã L1 ) 46.0 b 47.2 a 48.0 a 47.8 a Serum Protein content (g ã L1 ) 11 .6 b 12 .0 a 12 .1 a 12 .0 a LILCY (kg ã 10 0 L1 ) 26.7 b 26.6 b 27 .1 a 27.3 a LSCC 11 .9 12 .3 12 .1 12.2 Lambing type >1 b 94 10 2 ... (L30 -12 0) (L) Fat content (g ã L1 ) Protein content (g ã L1 ) Casein content (g ã L1 ) Serum protein content (g ã L1 ) LILCY (kg ã 10 0 L1 ) LSCC x 93 74.9 61. 1 48.4 12 .1 27.2 12 .1 SD 30.9 10 .5 ... [6,7 ,17 ] Trait L30 -12 0 Total fat content (TF) (g ã L1 ) TP TC SP LILCY LSCC 0.09 Milk yield (L30 -12 0) (L) TF 0.04 0. 01 0 .12 0 .11 0 .16 0.48 0.50 0.22 0. 41 0.03 0.99 0.66 0.29 0 .14 0.55 0.29 0 .12 ...
Ngày tải lên: 14/08/2014, 13:21
Báo cáo y học: "MALDI-TOF MS Combined With Magnetic Beads for Detecting Serum Protein Biomarkers and Establishment of Boosting Decision Tree Model for Diagnosis of Colorectal Cancer"
... 9286 .1 215 2.5 15 114 .2 2545.7 814 6 .1 2756.8 p 3.2 10 -6 3.5 10 -6 4.6 10 -6 5 .1 10 -6 5.8 10 -6 6.3 10 -6 6.8 10 -6 7 .1 10 -6 7.4 10 -6 8.9 10 -6 9.2 10 -6 9.4 10 -6 9.6 10 -6 9.9 10 -6 m/z 4599 .1 6837.5 2949 .1 ... 3400.7 3 817 .5 5905 .1 3 219 .4 619 4.6 4703.3 2686 .1 5545.4 13 270 .1 4985.2 5504.8 p 1. 2 10 -5 1. 5 10 -5 1. 9 10 -5 2 .1 10 -5 2.3 10 -5 2.4 10 -5 2.9 10 -5 3.3 10 -5 3.8 10 -5 4 .1 10 -5 4.5 10 -5 4.6 10 -5 6.2 10 -5 ... 3089.7 p 2.0 10 -8 4.2 10 -8 4.9 10 -8 7.3 10 -8 1. 5 10 -7 2.2 10 -7 4.5 10 -7 5.8 10 -7 6.4 10 -7 8.8 10 -7 9.8 10 -7 9.9 10 -7 1. 1 10 -6 2.0 10 -7 m/z 11 513 .2 13 748.8* 2 915 .8 5 910 .8 5703.4 3320.4 3975. 31 4647.4...
Ngày tải lên: 25/10/2012, 11:18
Tài liệu Báo cáo khoa học: Interaction between very-KIND Ras guanine exchange factor and microtubule-associated protein 2, and its role in dendrite growth – structure and function of the second kinase noncatalytic C-lobe domain docx
... CD2 -1 CD2-2 CD2-3 CD2 10 99 Inter- 600 250 767 15 0 934 IB: -v-KIND E F CD2 -1 CD2 -1- 1 634 CD2 -1- 2 667 CD2 -1- 3 7 01 CD2 -1- 4 CD2 -1- 5 735 CD2 -1- 6 702 CD2 -1- 7 668 CD2 -1- 8 635 CD2 -1- 6 -1 702 CD2 -1- 6-2 ... CD2 -1- 6-3 Interaction PD Input GST CD2 -1- 1 CD2 -1- 2 CD2 -1- 3 CD2 -1- 4 CD2 -1 767 250 15 0 PD 734 Input GST CD2 -1- 5 CD2 -1- 6 CD2 -1- 7 CD2 -1- 8 CD2 -1 600 734 744 755 250 PD Input GST CD2 -1- 6 -1 CD2 -1- 6-2 ... interaction MAP2 RII CD1 CD2 CD3 MBD RII InterMBD action CD 1 14 7 14 8–599 600 10 99 11 00 15 18 15 19 18 29 B IP PD Input Mouse IgG -MAP2 GST RII CD1 CD2 CD3 MBD A 250 15 0 IB: -v-KIND CD2 CD2 -1 CD2-2 CD2-3...
Ngày tải lên: 14/02/2014, 19:20
Tài liệu Báo cáo khoa học: SREBPs: protein interaction and SREBPs Ryuichiro Sato doc
... Sp1 required for synergistic activa- 626 13 14 15 16 17 18 tion with sterol regulatory element binding protein of low density lipoprotein receptor promoter Proc Natl Acad Sci USA 92, 610 2– 610 6 ... 3-hydroxy-3-methylglutaryl coenzyme A synthase and squalene synthase J Biochem 12 3, 11 91 11 98 Dooley KA, Millinder S & Osborne TF (19 98) Sterol regulation of 3-hydroxy-3-methylglutaryl-coenzyme A synthase ... Sato 19 Nishida T & Yasuda H (2002) PIAS1 and PIASxa function as SUMO-E3 ligases toward androgen receptor and repress androgen receptor-dependent transcription J Biol Chem 277, 413 11 413 17 20...
Ngày tải lên: 18/02/2014, 13:20
Tài liệu Báo cáo khoa học: Combinatorial approaches to protein stability and structure pdf
... Am Chem Soc 11 7, 7558–7559 10 3 Roy, S., Ratnaswamy, G., Boice, J.A., Fairman, R., McLendon, G & Hecht, M.H (19 97) A protein designed by binary 10 4 10 5 10 6 10 7 10 8 10 9 11 0 11 1 11 2 11 3 patterning ... Soc 12 0, 11 38 11 45 10 0 Ho, S.P & DeGrado, W.F (19 87) Design of a 4-helix bundle protein: synthesis of peptides which self-associate into a helical protein J Am Chem Soc 10 9, 67 51 6758 10 1 Raleigh, ... stability determinants Eur J Biochem 2 71, 16 23 16 29 61b Watters, A.L & Baker, D (2004) Searching for folded proteins in vitro and in silico Eur J Biochem 2 71, 16 15 16 22 62 Distefano, M.D., Zhong, A...
Ngày tải lên: 19/02/2014, 12:20
Tài liệu Báo cáo khoa học: The role of the SEA (sea urchin sperm protein, enterokinase and agrin) module in cleavage of membrane-tethered mucins pdf
... } 10 5 kDa 75 kDa 30 kDa 25 kDa 15 kDa MUC12FREG 35 kDa 30 kDa 25 kDa MUC3SEA 50 kDa 35 kDa MUC12SEA 10 5 kDa 75 kDa 50 kDa MUC3-GA U MUC12-CL D MUC3-CL MUC12FREG MUC12SEA MUC3SEA MUC3-GA MUC12-CL ... MUC12SEA MUC3SEA MUC3-GA MUC12-CL U T Palmai-Pallag et al MUC3-CL A MUC1F∆TR SEA modules and mucin cleavage 10 5 kDa 75 kDa 10 5 kDa 75 kDa 50 kDa 50 kDa 35 kDa 35 kDa 30 kDa 25 kDa 30 kDa 25 kDa ... QNLEILFRNGS¼¼¼IVVNSRMKFANSVPP J05582 U1 617 5 L 415 43 U36 918 L 415 46 AF1433 71 U765 51 AF147790 AF3 614 86 [12 ] AF430 017 AB 019 120 AF 017 776 AF157624 surface membrane [4] MUC1 subunits remain associated through...
Ngày tải lên: 19/02/2014, 18:20
Tài liệu Báo cáo Y học: Control of p70 ribosomal protein S6 kinase and acetyl-CoA carboxylase by AMP-activated protein kinase and protein phosphatases in isolated hepatocytes pot
... insulin Biochem Soc Trans 25, 12 38– 12 42 20 Hardie, D.G & Hawley, S.A (20 01) AMP-activated protein kinase: the energy charge hypothesis revisited Bioessays 23, 11 12– 11 19 21 Kemp, B.E., Mitchelhill, ... C.G (19 96) p70, S6 kinase: an enigma with variations Trends Biochem Sci 21, 18 1 18 5 Dufner, A & Thomas, G (19 99) Ribosomal S6 kinase signaling and the control of translation Exp Cell Res 253, 10 0 10 9 ... 273, 14 484 14 494 11 Pullen, N., Dennis, P.B., Andjelkovic, M., Dufner, A., Kozma, S.C., Hemmings, B.A & Thomas, G (19 98) Phosphorylation and activation of p70s6k by PDK1 Science 279, 707– 710 Ó...
Ngày tải lên: 22/02/2014, 07:20
Báo cáo khoa học: Muramyl-dipeptide-induced mitochondrial proton leak in macrophages is associated with upregulation of uncoupling protein 2 and the production of reactive oxygen and reactive nitrogen species docx
... rate B 10 0 10 1 PI 10 2 10 3 A 10 4 MB (10 0 lgÆmL )1) 10 0 ± 11 2 ± 14 .2 10 7 ± 10 .8 95.68 ± 4.6 LPS (1 lgÆmL )1) 10 0 ± 1. 5 10 2 ± 12 .3 98 ± 7.6 98.27 ± 8.2 10 0 10 1 10 2 10 3 Annex-FITC 10 4 10 0 10 1 10 2 10 3 ... Briefly, macrophages (1 · 10 6 well )1) were covered with 450 lL of Kreeb’s ringer phosphate buffer (12 3 mmolÆL )1 NaCl, 1. 23 mmolÆL )1 MgCl2, 4.9 mmolÆL )1 KCl and 16 .7 mmolÆL )1 Na phosphate buffer, ... Biochem J 3 61, 49–56 Echtay KS (2007) Mitochondrial uncoupling proteins – what is their physiological role? Free Radic Biol Med 43, 13 51 13 71 FEBS Journal 278 (2 011 ) 3054–3064 ª 2 011 The Authors...
Ngày tải lên: 05/03/2014, 23:20
Báo cáo khoa học: Concepts and tools to exploit the potential of bacterial inclusion bodies in protein science and biotechnology pdf
... between 16 60 and 16 48 cm )1, intramolecular b-sheets between 16 40 and 16 23 cm )1 and around 16 86 cm )1, whereas intermolecular b-sheet absorption in protein aggregates is found between 16 30 and 16 20 ... investigation of IB formation and characterization FEBS Journal 278 (2 011 ) 2408–2 418 ª 2 011 The Authors Journal compilation ª 2 011 FEBS 2 411 Potential of bacterial inclusion bodies P Gatti-Lafranconi et ... body formation FEBS Journal 278 (2 011 ) 2408–2 418 ª 2 011 The Authors Journal compilation ª 2 011 FEBS 2 417 Potential of bacterial inclusion bodies 58 59 60 61 62 63 64 65 66 67 68 69 P Gatti-Lafranconi...
Ngày tải lên: 06/03/2014, 00:20
Báo cáo khoa học: Protein aggregation and amyloid fibril formation prediction software from primary sequence: towards controlling the formation of bacterial inclusion bodies pot
... 5 31 536 14 Fernandez-Escamilla AM, Rousseaux F, Schymkowitz J & Serrano L (2004) Prediction of sequence-dependent 2434 18 19 20 21 22 23 24 25 26 27 28 FEBS Journal 278 (2 011 ) 2428–2435 ª 2 011 ... protein is shown in green Adapted from [ 31] with permission of BiomedCentral Ltd FEBS Journal 278 (2 011 ) 2428–2435 ª 2 011 The Author Journal compilation ª 2 011 FEBS S J Hamodrakas Fig Cartoon representations ... Similarly as above, for the construction of FEBS Journal 278 (2 011 ) 2428–2435 ª 2 011 The Author Journal compilation ª 2 011 FEBS 24 31 Software for controlling formation of bacterial inclusion bodies...
Ngày tải lên: 06/03/2014, 00:20
Báo cáo khoa học: Interaction of the general transcription factor TnrA with the PII-like protein GlnK and glutamine synthetase in Bacillus subtilis potx
... interaction of TnrA with GlnK, 40 nm GlnK (trimer) FEBS Journal 278 (2 011 ) 17 79 17 89 ª 2 011 The Authors Journal compilation ª 2 011 FEBS 17 81 Interaction of TnrA with GlnK and GS A Kayumov et al Fig BIAcore ... 2-oxoglutarate [12 ] Other nucleotides, such as ADP, AMP, and GTP, at concentrations of FEBS Journal 278 (2 011 ) 17 79 17 89 ª 2 011 The Authors Journal compilation ª 2 011 FEBS A Kayumov et al 1 3 mm had ... ATP at 10 mm was required to completely abolish complex formation; however, once the complex was formed, FEBS Journal 278 (2 011 ) 17 79 17 89 ª 2 011 The Authors Journal compilation ª 2 011 FEBS 17 83...
Ngày tải lên: 06/03/2014, 00:21
Báo cáo khoa học: Protein–protein interactions and selection: yeast-based approaches that exploit guanine nucleotide-binding protein signaling doc
... lessons FEBS Journal 277 (2 010 ) 19 82 19 95 ª 2 010 The Authors Journal compilation ª 2 010 FEBS 19 91 Screening systems using yeast G-protein signaling 10 11 12 13 14 15 16 17 18 J Ishii et al learned ... Acta 17 83, 13 81 13 95 Fields S & Song O (19 89) A novel genetic system to detect protein–protein interactions Nature 340, 245–246 Gyuris J, Golemis E, Chertkov H & Brent R (19 93) Cdi1, a human G1 ... 31 32 33 proteome-scale map of the human protein–protein interaction network Nature 437, 11 73 11 78 Paravicini G & Friedli L (19 96) Protein–protein interactions in the yeast PKC1 pathway: Pkc1p...
Ngày tải lên: 06/03/2014, 11:20
Báo cáo khoa học: Protein–protein interactions and selection: generation of molecule-binding proteins on the basis of tertiary structural information potx
... 277, 19 82 19 95 Tomizaki K, Usui K & Mihara H (2 010 ) Protein– protein interactions and selection: array-based techniques for screening disease-associated biomarkers 2 012 15 16 17 18 19 20 21 22 ... both affinity and size 10 11 12 13 14 References Winter G, Griffiths AD, Hawkins RE & Hoogenboom HR (19 94) Making antibodies by phage display technology Annu Rev Immunol 12 , 433–455 Watanabe H, ... Proc Natl Acad Sci USA 10 1, 12 467 12 472 39 Fellouse FA, Li B, Compaan DM, Peden AA, Hymowitz SG & Sidhu SS (2005) Molecular recognition by a binary code J Mol Biol 348, 11 53 11 62 40 Koide A, Bailey...
Ngày tải lên: 06/03/2014, 11:20
Báo cáo khoa học: Functional analysis of a murine monoclonal antibody against the repetitive region of the fibronectin-binding adhesins fibronectin-binding protein A and fibronectin-binding protein B from Staphylococcus aureus pot
... IgG)] 15 E 11 100 S.aureus SH1000 spa::KanR 10 0 15 E 11 14G6 80 80 60 60 40 40 20 Inhibition (%) S.aureus Cowan I spa::TetR 14 G6 20 0 10 0 0.2 0.4 0.6 0.8 0 .1 0 .12 S.aureus P1 spa::KanR 15 E 11 0.4 ... 15 E 11 0.4 0.6 0.8 0 .1 0 .12 S.aureus MRSA 19 0 15 E 11 100 14 G6 14 G6 80 0.2 80 60 60 40 40 20 20 0 0.2 0.4 0.6 0.8 0 .1 0 .12 0 mAb (μM) 0.2 0.4 0.6 0.8 0 .1 0 .12 Fig Effect of 15 E 11 on the binding of ... MINT-79 913 90, MINT79 914 05, MINT-79 914 20: fnbB (uniprotkb:Q53682) binds (MI:0407) to Fibronectin (uniprotkb:P027 51) by filter binding (MI:0049) l MINT-79 911 03, MINT-79 911 14, MINT-79 911 26, MINT-79 911 38,...
Ngày tải lên: 06/03/2014, 22:21
Báo cáo khoa học: NMR and molecular dynamics studies of an autoimmune myelin basic protein peptide and its antagonist Structural implications for the MHC II (I-Au)–peptide complex from docking calculations ppt
... epitopes, found in segments 1 14 , 22–34, 43–68, 67–75, 75–82, 83–96, 90–99, 11 4 12 1, 11 8 13 1, 12 5 13 1, 13 0 13 7 and 13 1 14 0 [23–26], which have antigenic properties Characterization of the molecular ... I-Au for the MBP (1 6) epitope, but substitution with Thr maintains the interaction [68] This is in accord- 1BX2 H90, K93, R99 1FV1 H126, H137 2IAD K90, R92 R108, R 111 , H 114 H328, H3 31 Human myelin ... Neurochem 55, 14 04 14 11 18 Martenson, R.E (19 81) Prediction of the secondary structure of myelin basic protein J Neurochem 36, 15 43 15 60 19 Mendz, G.L., Barden, J.A & Martenson, R.E (19 95) Conformation...
Ngày tải lên: 07/03/2014, 16:20
Báo cáo khoa học: "Age Prediction in Blogs: A Study of Style, Content, and Online Behavior in Pre- and Post-Social Media Generations" ppt
... times the collocation 18 -22 ldquot (’) t school x anything maybe because him 10 1 15 2 17 2 17 3 17 5 17 9 68 59 28-32 great find many years week post because him 16 6 16 7 17 7 17 9 18 1 19 0 80 85 38-42 may ... livejournal.com 2 010 # of Blogs # of Posts1 # of words1 age size 19 320 1. 4 million 295 million 11 5 21 256,000 50 million majority baseline 43.8% (13 -17 ) download year 13 17 23·27 33·37 18 ·22 28·32 38·42 ... Features 19 79 59.66 70.22 65.382 60.572 67 .16 2 19 84 61. 61 74. 61 67.282 62 .10 2 71. 312 53.4 71 73.452 55.5 41 74.002 75.26 76.39 77.45 77.76 79.22 80.88 74.8 80.36 74.73 80.54 74.39 77.20 79.96 81. 57 71. 26...
Ngày tải lên: 07/03/2014, 22:20
Báo cáo khoa học: NBR1 interacts with fasciculation and elongation protein zeta-1 (FEZ1) and calcium and integrin binding protein (CIB) and shows developmentally restricted expression in the neural tube pptx
... Berkowitz, R.S., Leavitt, T., Griths, C.T., Parker, Ó FEBS 2002 10 11 12 13 14 15 16 17 18 19 L., Zurawski, V.R Jr & Knapp, R.C (19 83) A radioimmunoassay using a monoclonal antibody to monitor ... and FEZ1 as interacting partners of NBR1 HF7c cells were cotransformed with either pACT2FEZ1 (Y 214 ), pACT2FEZ1 (Y156), pACT2FEZ1 (Y163), pACT2CIB (Y198) or pGAD424NBR1 and (i) pGBT9NBR1 (ii) ... protein J Cell Biol 14 5, 12 77 12 92 21 Cruts, M & Van Broeckhoven, C (19 98) Presenilin mutations in Alzheimer's disease Hum Mutat 11 , 18 3 19 0 22 Naik, U.P., Patel, P.M & Parise, L.V (19 97) Identi®cation...
Ngày tải lên: 08/03/2014, 10:20
Báo cáo khoa học: Biochemical properties of the human guanylate binding protein 5 and a tumor-specific truncated splice variant Mark Wehner and Christian Herrmann doc
... (kcalÆmol )1) TÆDS (kcalÆmol )1) 7.2 ± 0.3 2.6 ± 0.3 15 ± )14 .7 ± 0 .1 ) 31. 3 ± 0.4 ) 21. 4 ± 0.8 )7.7 ± 0.2 )23.5 ± 0.6 )14 .9 ± 0.9 11 ± ± 0.2 26 ± )16 .5 ± 0 .1 )25.3 ± 0.3 )38 .1 ± 0.8 )9.7 ± 0.2 )18 .2 ... 0.5 0 .19 ± 0.02b 1. 9 ± 0.3 mant-GTP 0. 014 ± 0.0 01 0.62 ± 0. 01 – 44 ± 4* hGBP5ta mant-GDP 0.066 ± 0.004 0 .13 ± 0. 01 0.23 ± 0. 01 3.5 ± 0.3 mant-GTPcS 0.072 ± 0.006 1. 4 ± 0 .1 1 .15 ± 0.05a 16 ± 0.20 ... lm )1 s )1) and mant-GTP (0. 014 lm )1 s )1) were quite similar In contrast, we found a five-fold faster dissociation of mant-GTPcS (1. 11 s )1) compared to mant-GDP (0.23 s )1) and mant-GTP (0.62 s )1) ...
Ngày tải lên: 15/03/2014, 10:20
Báo cáo khoa học: pyr RNA binding to the Bacillus caldolyticus PyrR attenuation protein – characterization and regulation by uridine and guanosine nucleotides potx
... 0.5 0.4 0.4 0.3 0.3 0.2 0.2 0 .1 0 .1 0.0 0.00 01 0.0 01 0. 01 B 0 .1 10 10 0 0.0 0.00 01 0.0 01 0. 01 1000 10 000 E 0.6 0 .1 10 10 0 10 00 10 000 10 0 000 10 10 0 10 00 10 000 10 0 000 0.7 0.6 0.5 Fraction RNA ... 0.2 0.2 0 .1 0.0 0.00 01 0.0 01 0. 01 0 .1 0 .1 10 10 0 10 00 10 000 0.0 0.00 01 0.0 01 0. 01 0 .1 PyrR (nM) C 0.7 Fraction RNA bound 0.6 0.5 0.4 0.3 0.2 0 .1 0.0 0.00 01 0.0 01 0. 01 0 .1 10 10 0 10 00 10 000 PyrR ... 10 00 10 00 900 750 500 250 10 0 50 0 .13 0.06 0.06 0.05 0 .11 0.29 0.84 1. 1 9.8 0 50 15 0 250 500 750 900 10 00 10 00 950 850 750 500 250 10 0 0 .13 0.05 0.06 0.09 0 .11 0 .17 0.40 0. 61 0.75 ND, not determined...
Ngày tải lên: 16/03/2014, 06:20