1 polygenic studies in the risk of arrhythmias

... conducted the analyses, explained the main findings, and wrote the manuscript All of the authors have read and approved the final manuscript. Competing interests The authors declare that they have ... of the population of Mainland China and about 18 % of the entire global human population We investigated 23 tagSNPs in six genes in the inflammation pathway for their associa-tions with CRC The ... genotype of the tagSNP rs2282151, the expression levels of HSP90AB1, and the risk of CRC As shown in Fig 3, the C allele of rs2282151 was associated with increased risk of CRC Meanwhile, the C allele...

Ngày tải lên: 20/09/2020, 18:20

... role in the initiation and propagation of hypoxia/ischemia-induced inflammation by secreting inflammatory chemokines that attract neutrophils and monocytes into the brain However, triggers of chemokine ... HIF-1 binds to HIF-1-binding sites in the target genes and activates their transcription We have recently shown that hypoxia-induced expression of IL-1β in astrocytes is mediated by HIF-1α In this ... Journal of Neuroinflammation BioMed Central Open Access Research Hypoxia-inducible factor-1 (HIF-1) is involved in the regulation of hypoxia-stimulated expression of monocyte chemoattractant protein-1...

Ngày tải lên: 19/06/2014, 22:20

... Trang 39Mrs Tuyet: At 2:30 in the afternoon we go to the field again We repair the banks of our plot of land Then my husband pumps water into it while I do the transplanting We work for about two ... Trang 35Mrs Tuyet: At 2:30 in the afternoon we go to the field again We repair the banks of our plot of land Then my husband pumps water into it while I do the transplanting We work for about two ... repair the banks of the plot of land Trang 29- to pump water into the plot of landTrang 31- to do the transplantingTrang 33II While you read1 Task 1: Multiple choice Pair work Trang 34 Mr Vy: The...

Ngày tải lên: 19/10/2014, 05:00

... about the verb tense to use in talking about daily routines - Remind Ss of some rules of the present simple tense - Recall the way of telling time - Close their books - Work in groups of three ... operate them, then compare their list with other groups’ - Introduce the topic of the listening text: ‘A day in the life of a cyclo driver’ and asks Ss to open their books - Ask Ss to work in pairs ... DAY IN THE LIFE OF LESSON 3: WRITING Preparing date: / / Teaching date: / / I Objectives: By the end of the lesson, Ss will be able to: - Find out the verbs in the past simple and the...

Ngày tải lên: 07/02/2015, 03:00

... Task 2 Trang 12In the afternoon and evening a Mr Vy and Mrs Tuyet go to the field again/ repairs the banks of their plot of land/pumps water /finish work/does the transplanting/have dinner/ watch ... repairs the banks of their plot of land/finish work/Watch TV/does the transplanting/have dinner/pumps water/go to bed.  d Mr Vy and Mrs Tuyet go to the field again/ repairs the banks of their ... go to the field again/ does the transplanting /repairs the banks of their plot of land/pumps water /finish work/have dinner/go to bed/watch TV  c Mr Vy and Mrs Tuyet go to the field again/ repairs...

Ngày tải lên: 12/02/2015, 07:00

... : things a person buys. food stall: place where people buy food or have meal. routine: have same meaning with habbit. office: whose place of bussiness. Trang 9 Ho Chi Minh city college of Education ... passengers to everywhere they want He is a cyclo driver Trang 7- Listen and number the order of the given words.Trang 8district: part of town or country drop: allow sb to get out off a transport. passenger: ... Education Tran Hung Dao street  Nguyen Thi Minh Khai school  Ben Thanh Market Thai Binh Market Trang 141 Mr Lam lives in District 1. Mr Lam lives in District 5 3 After Mr Lam gets up he rides...

Ngày tải lên: 26/05/2015, 16:57

... for the first time in my life 9 The moon (goes / went) round the earth 10 Mary’s grandfather died (at / in) 1998 11 They would really like to visit the art gallery (on Trang 18Put the verbs in ... occasionally, often / usually, always… _ I usually read books in the evening. _ He doesn’t often go out at night. _ She is always happy. CE16b Trang 14Arrange the given words in the correct order_ often ... the following sentences into the negative form _ Mary made a lot of cakes yesterday. 1 John was happy yesterday Trang 3CE12a CE 12Change the following sentences into the interrogative form _...

Ngày tải lên: 28/06/2015, 15:27

... explain them to the class: There are a lot of accidents in our lives, to understand them we learn part Writing Pre-writing: (10 minutes) - Ask student to read the narrative in task 1 - Explain ... best suits the meaning of the italicised words - Let students work individual or in - Ask students look through the passages then try to answer the questions in right way - Let them work in pairs ... works in a school He works in a factory He works in the field - Listen to the teacher andopen the book – Unit 1,part A: reading Trang 3- Ask students to use the suggestion intheir books to work in...

Ngày tải lên: 29/08/2016, 09:44

... Identifying -Events: some details of the narrative -Climax: the most important, thrilling, interesting detail -Conclusion: the end of the story, * Sts do the task individually then compare their ... water into it and Mrs Tuyet does the transplanting * Sts: fill in the 3rd column In the morning In the afternoon 4:30 5:15 5:30 7:45 10:30 11:30 2:30 6:30 pm Mr Vy gets up, goes to boil water, drinks ... 1Part A: READING (TCT-02) Aims Reading a passage about a farmer’s daily routine  Objectives - To train students in guessing meaning in context, understanding the whole passage and scanning for specific...

Ngày tải lên: 29/08/2016, 09:45

... Listen to the teacher - Check and explain them to the class: and open the books There are a lot of accidents in our Prewriting 10’ lives, to understand them we learn part Writing Tak1: Finding verbs ... read the narrative in task - Read the narrative - Ask the teacher if necessary - Look through the passage again and find all the verbs that used in the past simple and the connectors - Explain ... the life of Period 5: Lesson :Writing I Objectives: *Aims: By the end of the lesson, Ss wil be able to write a narrative by using given prompts * Language: The simple past of verbs and the connectors...

Ngày tải lên: 29/08/2016, 09:46

... give their answers - One completes the column “in the morning”; the other with “in the afternoon”; the restone with “after dinner” - Show the posters with their answers In themorning 4:30: the ... Guess the words and give their meanings by looking at the pictures: Trang 3leading the buffalo to the field, singing karaoke, doing homework , ploughing and harrowing, transplanting, teaching ... field,ploughing and harrowing, transplanting, pumping water into the land, getting up early,chatting with friends, drinking tea While-reading: 25’ - Ask Ss to read the text - Ask Ss to work in groups...

Ngày tải lên: 29/08/2016, 09:48

... groups and make a list of vehicles and the people who operate them, then compare their list with other groups’ - Introduce the topic of the listening text: ‘A day in the life of a cyclo driver’ and ... to read the passage again , and explain what they are going to do - Ask them to complete the note in 7 minutes, then discuss their answers with their partners - Ask three sts to report their answers ... 1: A DAY IN THE LIFE OF LESSON 1: READING Class Date of teaching - Students read and guess the meaning of words in contexts. - They read and answer questions about the texts - They practise...

Ngày tải lên: 29/08/2016, 09:51

... 4Gives the correct answer3 In the morning, he ploughs and harrows on his plot of land, drinks tea and smokes local tobaco during his break. 4 In the afternoon, they repair the banks of their ... Tiếng Anh 10 A READING I OBJECTIVES: - Ss read the text and guess the meaning of the new words, ask and answer base on the content of the text, scan and take note the information - Students ... of those adverbs of frequencyin its appropriate place in the given sentences Checks and calls 1 or 2 ss to read in front of the class Exercise3: (14mn) ASks Ss to choose the past simple of the...

Ngày tải lên: 29/08/2016, 09:52

... carefully.-Listen to the tape -Some Ss explain the answers, others listen - Work in pairs - Some pairs practice asking and answering in front of the class - Prepare the new lesson Trang 12II/TEACHING METHODSCommunication ... practice in front of the class - Sets the sence: Today, we are going to learn how to write a narrative - Asks Ss to read the passage in the book and find the new words - Writes the new words onthe ... to read the words - Asks Ss to work in pairs, read the passage again and find all the verbs that are used in the past simple and the connectors in the story - Calls on some Ss to give the verbs...

Ngày tải lên: 29/08/2016, 09:53

... air In Xai Pho, the air is fresh, and the water is very cool and clean The waterfall high about 10 metters,the water leak from above so it creates bubbles very nice On the right of it, there ... can help you with avoiding the sun On the left are fields, it’s very wonderfull Around of Xai Pho, there is not any drink or foods store, so, if you want to have a picnic in Xai Pho, you have ... because in summer, it’s very wonderful and you can swim, take some photos etc You should bring some clothes because the flow of water can make you wet, and you should bring some fast food Eating...

Ngày tải lên: 05/12/2016, 15:20

... A DAY IN THE LIFE OF…Welcome to our class Trang 2A GUESSING GAMELOOK AT THE WORKPLACES, THEN GUESS WHO WORKS IN THESE PLACES. Farmer Trang 3 UNIT 1: A DAY IN THE LIFE OF… Lesson 1: Reading/ ... lunch/ dinner/ go to bed ? - What do you often do in the morning/ afternoon/ evening? Trang 7II While you read.Reading: read the passage and then do the task that follow. Reading: read the passage ... your note with a partner. in the morning in the afternoon in the evening - 4 : 30:The alarm goes off and Mr Vy gets up - 5 : 15: leave your house - 5 : 30: arrive in the field - From 5 : 30...

Ngày tải lên: 11/12/2017, 12:00

... thought / gained Trang 6II While you write.Task 2. Work in groups Identify the events, the climax, and the conclusion of the story Then report the result.  The events: got on the plane, the plane ... began coughing and choking Then, just as we thought we had only minutes to live, the fire brigade arrived Firemen fought their way into the room and soon everyone was safely out of the building Luckily ... safely It was the most frightening experience of my life Trang 5I Before you write.-Task 1 Read the following passage and find all the verbs that are used in the past simple and the connectors...

Ngày tải lên: 11/12/2017, 12:00

... during his break). In the afternoon, they repair the banks of their plot of land Mr Vy pumps water into it while his wife does the transplanting. Yes, they are Because they love working and they ... 4:30 and then he goes down to the kitchen to boil some water for his morning tea. In the morning, he leads the buffalo to the field and then ploughs and harrows his plot of land, (drinks tea ... working and they love their children Trang 9In the morning In the afternoon after dinner 4:30: The alarm goes off and Mr Vy gets up. -5:15: leave your house , 5:30: arrive in the field, From 5:30...

Ngày tải lên: 11/12/2017, 12:00

... (to inf.) have/ want + sb/sth + to inf (be) + adj + to inf Exercise 1: Put the words in the correct order to make sentences, writing the main V in the present simple and making the other an infinitive ... in the next room The customs officer told him to open the briefcase => The customs officer made …  The customs officer made him open the briefcase The cat jumped through the window => The ... Rewrite the sentences, using the words given in brackets Example: - They arrived home late (He saw) => He saw them arrive home late They talked in the next room => I heard ……  I heard them talk in...

Ngày tải lên: 11/12/2017, 12:00

... PART C:LISTENING Trang 3I: Before you listen Trang 4In the picture, there is a fire engine with some firefighters who are trying to stop a big fire. WHAT’S HAPPENING IN THE PICTURE? There is a ... đánh giá cao Trang 6Task 1.Christina is being interviewed about the most unforgettable experience in her life Listen to the interview, and then decide whether the statements are true (T) or ... Trang 71.Christina is a businesswoman. 2 The fire happened three years ago 3 The fire started in the bedroom 4 When the fire started, Christina was reading a book. 5 Her mother came and rescued...

Ngày tải lên: 11/12/2017, 12:00