—scientific treatment and segregation with indeterminate sentence

IPython notebook essentials  compute scientific data and execute code interactively with numpy and scipy

IPython notebook essentials compute scientific data and execute code interactively with numpy and scipy

... and not rendered with an external program Commands that start with % and %% are called magic commands and are used to set up configuration options and special features The %pylab magic command ... Chapter 4, Handling Data with pandas, shows how to use the pandas library for data handling and analysis The main data structures provided by the library are studied in detail, and the chapter ... newsletters and receive exclusive discounts and offers on Packt books and eBooks • Fully searchable across every book published by Packt • Copy and paste, print, and bookmark content • On demand and

Ngày tải lên: 04/03/2019, 16:43

190 96 0
ANTITHROMBOTIC TREATMENT IN PATIENTS WITH CONCOMITANT INDICATION FOR DAPT AND CHRONIC ORAL ANTICOAGULATION

ANTITHROMBOTIC TREATMENT IN PATIENTS WITH CONCOMITANT INDICATION FOR DAPT AND CHRONIC ORAL ANTICOAGULATION

... patients with AF undergoing PCI 2010 (ESC) triple: VKA, aspirin, and clopidogrel in patients with AF undergoing PCI for as short a period as possible, which was based on expert opinions and not ... patients with AF undergoing PCI 2010 (ESC) triple: VKA, aspirin, and clopidogrel in patients with AF undergoing PCI for as short a period as possible, which was based on expert opinions and not ... patients with AF undergoing PCI 2010 (ESC) triple: VKA, aspirin, and clopidogrel in patients with AF undergoing PCI for as short a period as possible, which was based on expert opinions and not

Ngày tải lên: 23/08/2019, 15:19

28 109 0
First experience with Tolvaptan for the treatment of neonates and infants with capillary leak syndrome after cardiac surgery

First experience with Tolvaptan for the treatment of neonates and infants with capillary leak syndrome after cardiac surgery

... morbidity and mortality, therefore adverse effects especially on renal and cardiac impairment and long-term outcome could not be evaluated and need further evaluation in a prospective, randomized and ... ’ contributions AK collected and analyzed the data JM and OT designed the study and interpreted the data JM and AK drafted the main manuscript HM and CW performed and interpreted the statistical ... ap-proved for the treatment of hyponatremia associated with CHF in adults and the syndrome of inappropriate antidiuretic hormone secretion (SIADH) in adults and children The approval for treatment of

Ngày tải lên: 01/02/2020, 05:50

11 54 0
Real-world treatment and survival of patients with advanced non-small cell lung Cancer: A German retrospective data analysis

Real-world treatment and survival of patients with advanced non-small cell lung Cancer: A German retrospective data analysis

... On the other hand, female gender and treatment with therapies other than chemotherapy were associated with a lower risk of early death Conclusions: Despite the introduction of new treatments, the ... outpatient and inpatient diagnoses and treatments prescribed by all types of treating physicians and departments within the German healthcare system Diagnoses were identified based on inpatient and ... respective drugs [25] Patients with any treatment approved for SCLC, or with a treatment Trang 3approved for both SCLC and NSCLC were excluded.The complete list of SCLC and NSCLC-specific drugs (Supplementary

Ngày tải lên: 17/06/2020, 11:28

14 39 0
Treatment decisions, clinical outcomes, and pharmacoeconomics in the treatment of patients with EGFR mutated stage III/IV NSCLC in Germany: An observational study

Treatment decisions, clinical outcomes, and pharmacoeconomics in the treatment of patients with EGFR mutated stage III/IV NSCLC in Germany: An observational study

... current treatment pat-terns, clinical outcomes and resource use in patients withEGFR Mut + NSCLC in Germany In summary, RR, PFS and OS with first-line EGFR-TKI treatment for pa-tients with EGFR ... estimates of PFS and OS: patients with EGFR Mut + advanced NSCLC by therapy Kaplan-Meier estimates of progression-free survival (a and b) and overall survival (c and d), of patients with EGFR Mut ... with TKI and switch therapy (75.5% and 76.7%, respectively) compared with chemotherapy (57.1%) In terms of mean outpatient and inpatient costs, the chemo-therapy group had the highest costs and

Ngày tải lên: 24/07/2020, 00:35

10 26 0
Personalized treatment of women with early breast cancer: A risk-group specific cost-effectiveness analysis of adjuvant chemotherapy accounting for companion prognostic tests OncotypeDX and

Personalized treatment of women with early breast cancer: A risk-group specific cost-effectiveness analysis of adjuvant chemotherapy accounting for companion prognostic tests OncotypeDX and

... costly) for patients with 1) low ODX risk independent of AO classification; and 2) low AO risk and intermediate ODX risk For patients with an intermediate or high AO risk and an intermediate or ... probabilities of distant recurrence (with and without chemotherapy) especially within the risk groups L-I, I-L, I-I, H-L, H-I, L-N In the risk groups L-I, I-L and H-L, chemotherapy was dominated ... vinblastine, and vinorebline These studies were performed in the healthcare contexts of China, Canada, Germany, France, Italy, South Korea, Spain, UK, USA, The Netherlands, and Thailand In particular,

Ngày tải lên: 06/08/2020, 03:51

10 19 0
Prognostic impact of blood and urinary angiogenic factor levels at diagnosis and during treatment in patients with osteosarcoma: A prospective study

Prognostic impact of blood and urinary angiogenic factor levels at diagnosis and during treatment in patients with osteosarcoma: A prospective study

... diagnosis and during treatment Methods: Patients with localised or metastatic osteosarcoma enrolled in OS2005 and OS2006 studies between 2005 and 2011 were prospectively included in this study VEGF and ... di-agnosis, and the values at the end of treatment The association of each biomarker with the survival out-comes was evaluated by using Cox regression models stratified by treatment group (with or without ... in serum and/or urine of adults and children with malignancies, including osteosarcoma [11–14] However, a better knowledge of angiogenic factor levels and kinetics in body fluids during treatment

Ngày tải lên: 06/08/2020, 07:33

10 29 0
A multi-center phase II study and biomarker analysis of combined cetuximab and modified FOLFIRI as second-line treatment in patients with metastatic gastric cancer

A multi-center phase II study and biomarker analysis of combined cetuximab and modified FOLFIRI as second-line treatment in patients with metastatic gastric cancer

... cetuximab and mFOLFIRI was well tolerated and active as a second-line treatment for patients with metastatic gastric cancer Patients with low baseline plasma VEGF levels were associated with better ... treatment with paclitaxel and irinotecan in patients with MGC refractory to treatment with fluoropyrimidine plus platinum This study reported no significant differ-ence between paclitaxel and irinotecan ... oxaliplatin when combined with civ 5-Fu, but couldn’t when combined with bolus 5-Fu or capecitabine EGFR antagonists were com-bined with capecitabine and platinum in both EXPAND and REAL3 trials, the

Ngày tải lên: 19/09/2020, 21:30

10 27 0
Treatment and outcome of 32 patients with distant metastases of Hürthle cell thyroid carcinoma: A single-institution experience

Treatment and outcome of 32 patients with distant metastases of Hürthle cell thyroid carcinoma: A single-institution experience

... beginning of treatment in patients with and without neoadjuvant chemotherapy was 100 and 141 months (log-rank p = 0.256), respectively 5-year disease-specific survival for patients with and without ... of distant metastases in patients with and without RAI therapy was 93 months and 77 months, respectively Patients treated only with surgery and RAI without EBRT and/or chemotherapy had median disease-specific ... disease and distant progression was 7 cm and 6.65 cm, respectively (p = 0.75) Extrathyroid tumor growth was present in patients with and without initially proven metastatic disease and 75 % and 40

Ngày tải lên: 21/09/2020, 02:00

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Summary of Dissertation medical Doctor: Study on the immune modification and effectiveness of treatment in patients with lupus nephritis after induction treatment with mycophenolate mofetil

Summary of Dissertation medical Doctor: Study on the immune modification and effectiveness of treatment in patients with lupus nephritis after induction treatment with mycophenolate mofetil

... The ultimate goal of treating lupus nephritis is to improve the quality of life of the patient as well as to improve the patient's survival. After decades of multi­center clinical trial studies have been conducted with various drugs to find the best treatment strategy for patients. Treatment of lupus nephritis is based on different severity, with  or without histopathological classification, and is divided into two stages of induction and maintenance treatment ... thereby inhibiting the nucleotide nucleoside synthesis of guanosine, inhibiting the maturation and development of B and T lymphocytes IV, and class V Chapter 2: SUBJECT AND METHOD OF THE STUDY 1. Subject of the study 56 patients were diagnosed with lupus nephritis by clinical expert and renal biopsy and be treated by MMF with dose 2g per day at the Center of Allergic and Clinical Immunology, Bach Mai Hospital from August 8, 2015 to June 6 /2018 was enrolled this study ... Trang 104. Treatment of SLE and lupus nephritis 4.1. The treatment of SLE SLE is a complex pathology, damage of many organ systems, and at different times, lesions of varying degrees, with varying degrees of severity. Therefore, there is 

Ngày tải lên: 23/09/2020, 01:14

30 17 0
Phase Ib study evaluating a self-adjuvanted mRNA cancer vaccine (RNActive®) combined with local radiation as consolidation and maintenance treatment for patients with stage IV non-small

Phase Ib study evaluating a self-adjuvanted mRNA cancer vaccine (RNActive®) combined with local radiation as consolidation and maintenance treatment for patients with stage IV non-small

... chemotherapy (strata 1 and 2) or within six months of starting treatment with an EGFR TKI (erlotinib or gefitinib) (stratum 3) Patients will be vaccinated twice (Day 1 and Day 8) with CV9202 before ... IFN-gamma and TNF-alpha production by CD4+ and CD8 + T cells, and IFN-gamma ELISpot assay Vali-dated protocols (SOPs) and assay-specific response criteria are in accordance with harmonization panels and ... at least four cycles of platinum- and pemetrexed-based first-line chemotherapy, and with an indication for maintenance therapy with pemetrexed Table 3 Inclusion and exclusion criteria Inclusion

Ngày tải lên: 14/10/2020, 16:26

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Treatment of medulloblastoma with oncolytic measles viruses expressing the angiogenesis inhibitors endostatin and angiostatin

Treatment of medulloblastoma with oncolytic measles viruses expressing the angiogenesis inhibitors endostatin and angiostatin

... pi-pet tip The cells were subsequently washed with PBS and incubated with the medium containing VEGF (10 ng/ml for HUVEC and 20 ng/ml for bEnd.3) with or without MV conditioned media (10μg/ml) The ... removed and replaced with DMEM with 10% FBS and the cells were incubated an additional 48–72 hours at 37°C When the majority of the Vero cells had fused into syncytia, the media was removed and the ... supplemented medium with 10% FBS, endo-thelial cell growth supplements (Cascade Biologics Inc., Portland Oregon), and 2 mM L-glutamine at 37°C with 5% CO2 Measles virus plasmid construction and rescue

Ngày tải lên: 05/11/2020, 00:52

13 13 0
Efficacy and safety of pharmacological interventions in second- or later-line treatment of patients with advanced soft tissue sarcoma: A systematic review

Efficacy and safety of pharmacological interventions in second- or later-line treatment of patients with advanced soft tissue sarcoma: A systematic review

... patients with advanced STS pre-treated with anthracycline- and/orifosfamide-based therapy Results: The review identified six RCTs (one phase III and five phase II trials) and 94 non-randomised ... included trials and systematic reviews was also performed Study selection and characteristics The review included randomised controlled trials (RCTs) and non-randomised studies (prospective and retrospect-ive ... recruiting both patients with early stage andadvanced STS, or where studies included a mixed popula-tion of treatment-naive patients and patients previouslytreated with anthracycline- and/or ifosfamide-based

Ngày tải lên: 05/11/2020, 05:59

21 12 0
A prospective multicenter phase II study evaluating multimodality treatment of patients with peritoneal carcinomatosis arising from appendiceal and colorectal cancer: The COMBATAC

A prospective multicenter phase II study evaluating multimodality treatment of patients with peritoneal carcinomatosis arising from appendiceal and colorectal cancer: The COMBATAC

... chest, ab-domen and pelvis with oral, rectal and intravenous con-trast will be performed prior to treatment start, within 3 weeks after cytoreductive surgery (CRS) and HIPEC and 30 days after ... ana-lyses and the Dutch Trial may be explained by patient se-lection and the introduction of more efficient combined chemotherapeutic regimens with or without targeted drugs in the standard treatment ... prospective randomized phase III trial analyzing CRS and HIPEC with MMC plus adjuvant chemotherapy with 5-FU/folinic acid compared to systemic chemotherapy with 5-FU/folinic acid and palliative

Ngày tải lên: 05/11/2020, 07:09

10 13 0
Báo cáo y học: "Special considerations in the treatment of patients with bipolar disorder and medical co-morbidities"

Báo cáo y học: "Special considerations in the treatment of patients with bipolar disorder and medical co-morbidities"

... associated with risperidone, quetiapine and ziprasidone, and more frequently with clozapine and olanzapine [26,27] http://www.general-hospital-psychiatry.com/content/3/1/7 Of note, those with baseline ... 50% in patients with CHF [41] Women with obesity and polycystic ovaries or hyperandrogenism treated with valproate have also been shown to have elevations in serum triglycerides and low HDL to ... weighed at baseline and again two weeks after beginning treatment If the patient gains four pounds or more, behavioral interventions of diet and exercise and a consultation with a nutritionist...

Ngày tải lên: 25/10/2012, 10:51

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DATA HANDLING IN SCIENCE AND TECHNOLOGY -VOLUME 4 Advanced scientific computing in BASIC with applications in chemistry, biology and pharmacology potx

DATA HANDLING IN SCIENCE AND TECHNOLOGY -VOLUME 4 Advanced scientific computing in BASIC with applications in chemistry, biology and pharmacology potx

... DATA HANDLING IN SCIENCE AND TECHNOLOGY -VOLUME Advanced scientific computing in BASIC with applications in chemistry, biology and pharmacology DATA HANDLING IN SCIENCE AND TECHNOLOGY ... Applications in Chemistry, Biology and Pharmacology by P Valk6 and S.Vajda DATA HANDLING IN SCIENCE AND TECHNOLOGY -VOLUME Advisory Editors: B.G.M Vandeginste, O.M Kvalheim and L Kaufman Advanced scientific ... handle a number of realistic p r o b l w with the power and sophistication needed by professionals and with simple, step - by step introductions for students and beginners In spite of their broad...

Ngày tải lên: 22/03/2014, 23:20

340 2,4K 2
scientific american   -  2003 11  -  strings and spacetime with 11 dimensions

scientific american - 2003 11 - strings and spacetime with 11 dimensions

... and applications of cloning American statesman and science enthusiast Thomas Jefferson once pondered this theme himself, postulating in 1810 that “laws and institutions must go hand in hand with ... use and destruction of cloned human embryos— even in the service of the noble cause of science and medicine In keeping with our mandate, the council has sought to “articulate fully the complex and ... substance? and revolutionize the stationary HOW CHILDREN LEARN, as studied by Jean Piaget, 1953 Has any man seen it with his generation of power The gas tureyes, handled it with his hands bine,...

Ngày tải lên: 12/05/2014, 16:18

87 390 0
Báo cáo hóa học: " Comparison of three rapamycin dosing schedules in A/J Tsc2+/- mice and improved survival with angiogenesis inhibitor or asparaginase treatment in mice with subcutaneous tuberous sclerosis related tumors" docx

Báo cáo hóa học: " Comparison of three rapamycin dosing schedules in A/J Tsc2+/- mice and improved survival with angiogenesis inhibitor or asparaginase treatment in mice with subcutaneous tuberous sclerosis related tumors" docx

... patients with kidney angiomyolipomas associated with TSC and/ or LAM treated with rapamycin In a cohort of 20 TSC and/ or LAM patients treated with rapamycin for 12 months and then followed off of treatment ... consisting of males and females, Tsc2+/+ months consisting of males and females, Tsc2+/- 12 months consisting of males and females, and Tsc2 +/+ 12 months consisting of males and females To determine ... Hospital Boston, Boston, MA) and were compliant with federal, local, and institutional guidelines on the care of experimental animals Treatment of subcutaneous tumors with asparaginase, vincristine,...

Ngày tải lên: 18/06/2014, 16:20

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Báo cáo y học: " A comparison of olanzapine and risperidone on the risk of psychiatric hospitalization in the naturalistic treatment of patients with schizophrenia" ppsx

Báo cáo y học: " A comparison of olanzapine and risperidone on the risk of psychiatric hospitalization in the naturalistic treatment of patients with schizophrenia" ppsx

... customarily dispensed to patients with schizophrenia in usual care settings [10], with daily mean and (median) doses of 14.5 mg (14.3 mg) and 4.5 mg (4.3 mg) for the OLZ and RIS treatment groups, respectively ... risperidone treatment group (19.0 days) than for the OLZ treatment group (7.3 days) As figure illustrates, treatment with OLZ was associated with significantly fewer hospitalization days starting with ... peoples' lives, and interruptions of patients' mental health treatments in the community Our findings documented the consistency with which treatment with olanzapine was associated with a lower...

Ngày tải lên: 08/08/2014, 20:23

11 522 0
Báo cáo y học: "Physical function, disease activity, and health-related quality-of-life outcomes after 3 years of adalimumab treatment in patients with ankylosing spondylitis" potx

Báo cáo y học: "Physical function, disease activity, and health-related quality-of-life outcomes after 3 years of adalimumab treatment in patients with ankylosing spondylitis" potx

... of treatment in improving and sustaining patient-reported physical functioning and HRQOL Materials and methods Patients and study design The Adalimumab Trial Evaluating Long-Term Efficacy and ... signs and symptoms, physical function, and HRQOL in patients with active AS [16,32] Maintenance of improvement Page of 12 (page number not for citation purposes) in clinical signs and symptoms (without ... placebo-treated and adalimumab-treated patients for the BASFI and ASQOL Table Baseline demographic and clinical characteristics of patients with AS: comparison of patients entering double-blind and open-label...

Ngày tải lên: 09/08/2014, 14:22

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