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Discriminative ability of the generic and conditionspecific Child-Oral Impacts on Daily Performances (Child-OIDP) by the Limpopo-Arusha School Health (LASH) Project: A cross-sectional study

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Generic and condition-specific (CS) oral-health-related quality-of-life (OHRQoL) instruments assess the impacts of general oral conditions and specific oral diseases. Focusing schoolchildren from Arusha and Dar es Salaam, in Tanzania.

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R E S E A R C H A R T I C L E Open Access

Discriminative ability of the generic and condition-specific Child-Oral Impacts on Daily Performances (Child-OIDP) by the Limpopo-Arusha School Health (LASH) Project: A cross-sectional study

Hawa S Mbawalla1,2,3, Matilda Mtaya3, Joyce R Masalu3, Pongsri Brudvik4and Anne N Astrom1*

Abstract

Background: Generic and condition-specific (CS) oral-health-related quality-of-life (OHRQoL) instruments assess the impacts of general oral conditions and specific oral diseases Focusing schoolchildren from Arusha and Dar es Salaam, in Tanzania, this study compared the discriminative ability of the generic Child OIDP with respect to dental caries and periodontal problems across the study sites Secondly, the discriminative ability of the generic-and the

CS Child OIDP attributed to dental caries, periodontal problems and malocclusion was compared with respect to various oral conditions as part of a construct validation

Methods: In Arusha, 1077 school children (mean age 14.9 years, range 12-17 years) and 1601 school children in Dar es Salaam (mean age 13.0 years, range 12-14 years) underwent oral clinical examinations and completed the Kiswahili version of the generic and CS Child-OIDP inventories The discriminative ability was assessed as

differences in overall mean and prevalence scores between groups, corresponding effect sizes and odd ratios, OR Results: The differences in the prevalence scores and the overall mean generic Child-OIDP scores were significant between the groups with (DMFT > 0) and without (DMFT = 0) caries experience and with (simplified oral hygiene index [OHI-S] > 1) and without periodontal problems (OHI-S≤ 1) in Arusha and Dar es Salaam In Dar es Salaam, differences in the generic and CS Child-OIDP scores were observed between the groups with and without dental caries, differences in the generic Child-OIDP scores were observed between the groups with and without

periodontal problems, and differences in the CS Child-OIDP scores were observed between malocclusion groups The adjusted OR for the association between dental caries and the CS Child-OIDP score attributed to dental caries was 5.4 The adjusted OR for the association between malocclusion and CS Child-OIDP attributed to malocclusion varied from 8.8 to 2.5

Conclusion: The generic Child-OIDP discriminated equally well between children with and without dental caries and periodontal problems across socio-culturally different study sites Compared with its generic form, the CS Child-OIDP discriminated most strongly between children with and without dental caries and malocclusion The CS Child OIDP attributed to dental caries and malocclusion seems to be better suited to support clinical indicators when estimating oral health needs among school children in Tanzania

* Correspondence: anne.nordrehaug@cih.uib.no

1

Department of Clinical Dentistry, Community Dentistry, University of Bergen,

Bergen, Norway

Full list of author information is available at the end of the article

© 2011 Mbawalla et al; licensee BioMed Central Ltd This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and

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Planning dental treatment within a public health system

requires information on the prevalence and distribution

of oral diseases [1] However, normative treatment

needs, reflected in clinical oral indicators, provide little

information about the patients’ self-perceived treatment

needs To overcome this limitation, oral-health-related

quality-of-life (OHRQoL) instruments have been

devel-oped to assess the impact of oral health on daily life

activities [2] According to Locker [3], the subjective

perception of oral health and treatment needs is

consid-ered to be the consequence of oral conditions, although

studies that have investigated the relationship between

subjective and clinical oral health indicators have shown

both strong and weak significant associations and even

the absence of any relationship [4] Numerous studies

have identified a gap between professionally and

self-defined oral health, suggesting that they document

dif-ferent dimensions of the human experience, which are

conceptually and often empirically distinct, with

differ-ent implications for treatmdiffer-ent need [5] Consequdiffer-ently,

OHRQoL instruments are recommended to supplement

clinical measures and as adjuncts to them [4]

Whereas clinical oral health indicators refer to specific

oral conditions, such as dental caries, periodontal

dis-ease, and malocclusion, most OHRQoL indicators are

generic in that they assess the overall impact of oral

problems by considering numerous oral conditions In

contrast, condition-specific (CS) OHRQoL measures

focus on particular diseases, conditions, symptoms,

functions, or populations, and should be used when any

of these attributes must be assessed [1] CS instruments

provide information about the consequences of a

speci-fic, untreated oral condition and the corresponding

ben-efits of its treatment This might make CS instruments

more sensitive to small but clinically relevant changes in

oral diseases than both generic HRQoL and OHRQoL

instruments [1,6] Assuming that oral conditions have

consequences for more widespread health issues, Allen

et al [7] compared the validity of the Oral Health

Impact Profile (OHIP) with a generic HRQoL

instru-ment, SF36, in edentulous patients seeking implants or

conventional dentures Whereas OHIP discriminated

between three clinically disparate groups, SF36 did not

Lee et al [8] compared the performances of the

Pedia-tric Quality of Life Inventory and the Early Childhood

Oral Health Impact Scale and showed that the latter

instrument was superior in identifying those children

affected by early childhood caries from those without

caries However, with few exceptions, the superiority of

CS measures to generic HRQoL and OHRQoL

instru-ments has yet to be established [1,9-11]

One of the most commonly used OHRQoL

instru-ments, the Oral Impact on Daily Performances (OIDP), is

designed to be used both as a generic and a CS instru-ment As a CS instrument, it can link specific oral condi-tions to an individual’s quality of life [11] The Child-OIDP [12], derived from the adult Child-OIDP version, has been shown to be applicable to school children across occidental and non-occidental socio-cultural contexts, when used as self-administered questionnaires or in face-to-face interviews [for a review, see [13]] However, there

is little empirical evidence about the relationship between the Child-OIDP and various oral diseases or on whether those relationships vary across socio-cultural contexts Few studies have compared the capacities of the generic and CS Child-OIDP inventories to discriminate between groups with different levels of normative treatment needs, as part of a construct validity assessment [14]

In Tanzania, dental diseases have remained at moderate levels, and approximately 30%-40% of the population, irre-spective of age, is reportedly free of dental caries However, Tanzanian children have for many years demonstrated a high prevalence of untreated dentinal lesions, with a majority located in molars, which show relatively slow pro-gression [15] Recently, 19.2% of a sample of rural school children was identified with normative treatment needs for dental caries [16] Periodontal problems have been reported to account for 80% of all oral diseases in the Tan-zanian population [17] Poor oral hygiene at an age of 15 years or older is very common (65%-99%) and the preva-lence of gingivitis is reported to range from 80% to 90% [18,19] Previous studies have indicated a wide variation in the prevalence of malocclusion, ranging from 45% to 97% among school children [20] Exposure to dental services is low in this country, particularly in rural areas, and dental pain and discomfort have been cited as common reasons for seeking dental care [17] Information is needed about the generic and CS impacts of periodontal disease, dental caries, and malocclusion on children’s quality of life, to guide the assessment of the dental treatment needs of Tanzanian school children

Purpose

Focusing on school children, this study compared the discriminative ability of the generic Child-OIDP for den-tal caries and periodonden-tal problems across socio-cultu-rally different study sites (Arusha and Dar es Salaam) in Tanzania The discriminative ability of the generic and

CS Child-OIDP attributed to dental caries, periodontal problems, and malocclusion were then compared with respect to various oral conditions among school children

in Dar es Salaam, as part of a construct validation

Methods Arusha site

As a part of the Limpopo-Arusha school health project (LASH), a cross sectional study was performed in 2009

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in Arusha, northern Tanzania, focusing on secondary

school students In this study area, the fluoride

concen-tration in the drinking water has been estimated to be

3.6 mg/L [21] Fifty-nine public secondary schools were

listed, 31 of which fulfilled the inclusion criteria of

being a public school with a student enrolment of more

than 200 A one-staged stratified cluster design was

uti-lized, with the school as the primary sampling unit All

available students in forms I and II (i.e the two first

school years) in 20 selected schools (10 urban and 10

rural) were invited to participate in the study

Ulti-mately, 1163 and 1249 students from urban and rural

schools, respectively, were included in the study (2412/

2988 participation rate, 80.7%) A structured

question-naire, including 165 questions, was initially developed in

English, translated into Kiswahili, and then

back-trans-lated into English by independent translators qualified

in English and Kiswahili This questionnaire was

com-pleted by the students in a classroom setting under the

supervision of trained research assistants In total, 1077

of the 1331 participants (participation rate, 80.9%)

enrolled in a random sub-sample of 10 schools (five

urban and five rural) consented to undergo a full-mouth

clinical oral examination A sample size of 1200 school

children was calculated to be sufficient for two-sided

tests, assuming the prevalence of oral impact to be 0.40

and 0.50 in children with and without an orthodontic

anomaly, respectively, a significance level of 5%, power

of 90%, and a design factor of 2 [22] The sampling

pro-cedure has been described in detail elsewhere [23]

Par-ents and studPar-ents gave their written informed consent

to participate in both the main questionnaire survey and

the clinical examination Permission to conduct the

study was granted by the school authorities and the

Ministries of Education and Health of Tanzania Ethical

approval was given by Muhimbili University of Health

and Allied Sciences, the National Institutes for Medical

Research in Tanzania and the Regional Committee for

Research Ethics of Western Norway (REK Vest)

Dar es Salaam site

A cross-sectional survey was conducted in 2006 in Dar

es Salaam, the commercial capital of Tanzania Dar es

Salaam is divided into three districts, and two of them,

Kinondoni and Temeke, are quite diverse in their

socio-demographic profiles: Kinondoni has higher

employ-ment and literacy rates, and a greater proportion of the

population uses electricity (the most expensive energy

source) for cooking [24] All districts have drinking

water with a fluoride content of about 1 mg/L (1 ppm)

The study population comprised children attending

grade 7 (i.e the last school year) in public primary

schools A stratified proportionate two-staged cluster

sampling design was utilized, with public primary

schools as the primary sampling unit A sample size of

1200 school children aged 12-14 years was calculated to

be sufficient for two-sided tests, assuming the preva-lence of oral impact to be 0.40 and 0.50 in children with and without an orthodontic anomaly, respectively, a sig-nificance level of 5%, power of 90%, and a design factor

of 2 [22] In total, 1601 children completed the clinical oral examination and a structured interview in the school setting The interview schedule was developed in English and translated into Kiswahili by two trained research assistants Oral health professionals reviewed the interview schedules for semantic, experiential, and conceptual equivalence Sensitivity to culture and the selection of appropriate words were considered The interview schedule was piloted before its administration Informed consent was obtained from parents and stu-dents Ethical approval was obtained from all the rele-vant persons, authorities, and committees in Tanzania and from the Regional Committee for Research Ethics

of Western Norway (REK Vest) For a more detailed description of the sampling procedure, see [20]

Variables and measurements

Identical variables were assessed at both study sites in terms of socio-demographic factors: age, sex, place of residence, and religious affiliation Oral-health-related quality of lifewas measured using a Kiswahili version [20] of the eight-item generic and CS Child-OIDP inventories (e.g., during the preceding three months, how often have you had problems with your teeth and mouth that caused you difficulty with: eating, speaking, cleaning your teeth, smiling, sleeping, emotional balance, study, or social contact) Each item was scored on a scale of 0-3, which equated to (0) never, (1) once or twice a month, (2) once or twice a week, and (3) every day/nearly every day The generic Child-OIDP was assessed at both study sites, whereas the CS Child-OIDP was assessed only in Dar es Salaam The generic and CS Child-OIDP simple count (SC) scores were calculated

by summing the dichotomized frequency items of (1) affected (original score 1-3) and (0) not affected (original score 0) The participants in Dar es Salaam were also asked to identify from a list of oral problems those that they believed caused the specific impact The prevalence

of generic and CS oral impact was calculated as the per-centage of children with overall generic and CS Child-OIDP SC scores above zero The CS Child-Child-OIDP assessed only those impacts related to the specific oral conditions linked to various types of treatment needs

CS impacts related to toothache were considered to be

CS Child-OIDP attributed to dental caries, whereas CS impacts related to swollen gums, bleeding gums, and ulcerous gums were considered CS Child-OIDP attribu-ted to periodontal problems Finally, CS impacts relaattribu-ted

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to spaces between the teeth and bad positioning of the

teeth were considered CS Child-OIDP attributed to

malocclusion

Clinical oral examination

Clinical oral examinations were carried out at each site

by one trained and calibrated dentist, together with

den-tal assistants Caries experience was assessed under field

conditions and scored according to the criteria

described by the World Health Organization [25] Oral

hygiene was assessed using the simplified Oral Hygiene

Index (OHI-S) [26] Plaque was assessed on six index

teeth in terms of (0) no debris present, (1) soft debris

covering more than one-third of the tooth surface, (2)

soft debris covering more than one-third but not more

than two-thirds of the tooth surface, or (3) soft debris

covering more than two-thirds of the tooth surface

Cal-culus was assessed on six index teeth and recorded as

(0) no calculus present, (1) supra-gingival calculus

cov-ering at most one-third of the tooth surface, (2)

supra-gingival calculus covering more than one-third but not

more than two-thirds of the tooth surface, or (3)

supra-gingival calculus covering more than two-thirds of the

tooth surface For each individual, the debris and

calcu-lus scores for each index tooth were summed and

divided by the number of teeth assessed (range 0-3)

The average debris score was dichotomized into 0/1 =

good/bad debris score (cut-off point 0.7) The average

calculus score was dichotomized into 0/1 = good/bad

calculus score (cut-off point 0.7) The OHI-S was

calcu-lated by summing the debris and calculus scores (range

0-6) For the analysis, the OHI-S scores were

dichoto-mized into 0 = good oral hygiene (OHI-S≤ 1) and 1 =

poor oral hygiene (OHI-S > 1) Occlusion was recorded

according to Björk et al [27], as modified by al-Emran

et al [28] A sum score for malocclusions (SMO) was

calculated based on a diagnosis of the absence

(0)/pre-sence (1) of the following phenomena: maxillary overjet,

mandibular overjet, class II or class III molar occlusion,

open bite, deep bite, lateral cross bite, midline shift,

scis-sors bite, crowding, or spacing Detailed information

about the criteria used for the single malocclusion

diag-noses are presented in a previous study [20]

Reproducibility and internal consistency reliability

In Dar es Salaam and Arusha, duplicate clinical

exami-nations were carried out on randomly selected

sub-sam-ples of 71 and 25 individuals, respectively, considered to

be representative of the study subjects In Dar es

Sal-aam, the kappa statistics were 0.93 for the decayed,

missed and filled teeth (DMFT) scores, 0.74 for the

OHI-S scores, 0.78 for the midline shift scores, 0.79 for

the deep bite scores, 0.82 for the mandibular overjet

scores, 0.93 for the maxillary overjet scores, and 0.97 for

the spacing scores The kappa statistics were 1 for the scores for open bite, angle classification, cross bite, scis-sor bite, and crowding The test-retest reliability for the eight Child-OIDP items ranged from 0.7 (emotional state) to 1.00 (eating, speaking, cleaning teeth, sleeping, smiling, and social contact) In Arusha, the kappa statis-tics were 0.78, 0.67, and 0.83 for the calculus, OHI-S, and DMFT scores, respectively These figures indicate good and very good intra-examiner reliability [25] The internal consistency reliability (standardized itema) of the Child-OIDP inventory was 0.85 in Arusha and 0.77

in Dar es Salaam, which agree with the values obtained previously in Tanzania [see [16,20]]

Statistical analysis

Statistical Package for the Social Sciences (SPSS) version 15.0 was used for the data analysis We adjusted for the design effect at both sites using STATA 10.0 The dis-criminative abilities of the generic and CS Child-OIDP scores were examined by comparing the distributions of both scores between groups with various levels on clini-cal indicators Bivariate analyses of the Child-OIDP pre-valence scores were conducted using cross-tabulations and c2

statistics The overall generic and CS Child-OIDP scores were not normally distributed and the clin-ical groups were compared using the Mann-Whitney U test To interpret the mean differences in scores across groups, the effect sizes were calculated as the mean dif-ferences between groups divided by the pooled standard deviations The widely accepted thresholds of 0.2, 0.5 and 0.8 were used to define small, moderate, and large effect sizes [29] Comparison of the generic and CS Child-OIDP attributed to dental caries, periodontal pro-blems, and malocclusion were evaluated with Cochran’s

Q (for prevalence) and Friedman’s test (for the overall scores) for related samples Multiple-variable analyses were conducted using standard logistic regression with odds ratios (ORs) and 95% confidence intervals (CIs)

Results Sample characteristics

As shown in Table 1, the percentage distribution of the participants’ socio-demographic data and generic Child-OIDP scores varied systematically according to the study site In Arusha, the study group of 1077 secondary school children (response rate, 80.9%) had a mean age

of 14.98 years (SD 1.4), and included 46.6% boys The mean OHI-S scores were 1.1 (SD 0.8), and the preva-lence of poor oral hygiene (OHI-S > 1) was 44.8% The mean DMFT was 1.2 (SD 1.8) and the prevalence of car-ies (DMFT > 0) was 43.5% In Dar es Salaam, the study group of 1601 primary school students had a mean age

of 13.0 years and comprised 39.5% boys The mean DMFT score was 0.38 (SD 0.85), caries prevalence was

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22.0%, the mean OHI-S score was 1.1 (SD 0.5), and the

prevalence of OHI-S scores > 1 was 45.3% The mean

sum malocclusion score (SMO) was 1.1 (SD 1.0) and

the prevalence of malocclusion was 63.8% Midline shift

(22.5%), spacing of at least 2 mm (21.9%), open bite

(16.1%), and maxillary overjet were the most commonly

diagnosed malocclusions, and mandibular overjet ≥ 2

mm (0.2%), cross bite (5.1%), and sagittal molar

relation-ship class III (2.0%) were the least commonly diagnosed

malocclusions [20]

Comparing the discriminative ability of the generic

Child-OIDP across study sites

Statistically significant differences were observed in the

prevalence and overall generic Child-OIDP mean scores

between students with and without caries and with and

without poor oral hygiene (Table 2) The effect sizes of

the mean differences in the generic Child-OIDP scores

between groups without and with dental caries were 0.3

(mean 1.3, SD 1.9 without caries; mean 2.0, SD 2.4 with

caries) and 0.2 (mean 0.5, SD 1.1 without caries; mean

0.8, SD 1.4 with caries) in Arusha and Dar es Salaam,

respectively The corresponding effect sizes between the

groups with and without a treatment need for

periodon-tal problems were 0.2 (mean 1.3, SD 2.0 in children with

a good OHI-S score; mean 1.9, SD 2.3 in children with a

poor OHI-S score) and 0.1 (mean 0.5, SD 1.1 in children with a good OHI-S score; mean 0.7, SD 1.3 in children with a poor OHI-S score; not shown in Table 2) A multi-ple-variable logistic regression analysis was conducted with the generic Child-OIDP scores as the dependent variable and the DMFT and OHI-S scores as the inde-pendent variables, while adjusting for study site and potentially confounding socio-demographic factors The interaction effects between the clinical indicators and the study sites were not statistically significant, suggesting that the discriminative capacity of this index with respect

to dental caries and periodontal problems did not vary between the study sites The site-specific OR estimates with DMFT > 0 were 1.6 (95% CI 1.3-1.9) in Arusha and 1.5 (95% CI 1.2-2.1) in Dar es Salaam The corresponding ORs when OHI-S scores > 1 were 1.6 (95% CI 1.1-2.0) in Arusha and 1.2 (95% CI 1.0-1.5) in Dar es Salaam (not shown in Table 2)

Comparing the discriminative ability of the generic and

CS Child-OIDP inventories

When the generic Child-OIDP was used, statistically sig-nificant differences in the overall mean scores were observed between the groups with and without decayed teeth, missing teeth and poor plaque scores The corre-sponding effect sizes of the mean differences were 0.2, 0.2, and 0.2, respectively As shown in Table 3, there were corresponding statistically significant differences between the groups in the prevalence of the generic Child-OIDP The adjusted ORs for the association between decayed teeth (DT > 0) and the generic Child-OIDP score was 1.5 The corresponding figure for the association between a poor plaque score and the generic Child-OIDP score was 1.3 As shown in Table 4, there were significant differences in the overall scores between

Table 1 Percentage distributions (n) of participants by

socio-demographic and clinical characteristics and study

site

Arusha % (n) Dar es Salaam % (n) Sex

Male 46.6 (502) 39.5 (632)

Female 53.4 (575) 60.5 (969)**

Age

Younger (12-13 yr) 12.3 (132) 69.6 (1115)

Older ( ≥ 14 yr) 87.7 (945) 30.4 (486)**

Religious affiliation

Christian 84.7 (877) 44.4 (711)

Other 15.3 (148) 55.6 (890)**

Residence

Urban 40.7 (438) 70.5 (1129)

Rural 59.3 (639) 29.5 (472)**

Oral hygiene status

Good (OHI-S ≤ 1) 55.2 (594) 54.7 (876)

Poor (OHI-S > 1) 44.8 (483) 45.3 (725)

Caries experience

DMFT = 0 56.5 (609) 78.0 (1249)

DMFT > 0 43.5 (468) 22.0 (352)

Generic Child-OIDP

No impact (OIDP = 0) 49.3 (509) 71.4 (1143)

Impact (OIDP > 0) 50.7 (524) 28.6 (458)**

** P < 0.001

Table 2 Discriminative capacity of the generic Child-OIDP for school children with and without normative

treatment needs for dental caries or periodontal problems across the Arusha and Dare es Salaam study sites

mean (SD) [effect size]

% (n) Adjusted OR (95%

CI) Dental caries

DMFT = 0 0.8 (1.5) 32.7 (601) 1 DMFT > 0 1.5 (2.1)** [0.4] 47.8 (381)

**

1.5 (1.3-1.9) a

Periodontal OHI-S < 1 (good)

0.8 (1.6) 33.9 (491) 1 OHI-S > 0

(poor)

1.2 (1.8)** [0.2] 41.4 (491)

**

1.6 (1.2-1.6) a

a

ORs for generic Child-OIDP adjusted for study site, age, sex, urban/rural residence, and religion

**P < 0.001, *P < 0.05

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the groups with and without DMFT > 0, with and

with-out DT > 0, and with and withwith-out missed teeth (MT >

0) when the CS Child-OIDP attributed to dental caries

was used The corresponding effect sizes were 0.8, 0.7,

and 0.7, respectively There were also significant

differ-ences in the overall mean scores between the groups

that did and did not require normative treatment for

malocclusion when the CS Child-OIDP attributed to

malocclusion was used The effect sizes ranged from 0.1

(open bite, midline shift, and the summed malocclusion

score) to 0.5 (crowding) The adjusted ORs for the

asso-ciation between normative treatment of dental caries

and the CS Child-OIDP attributed to dental caries were

5.4, 4.7, and 4.2 with respect to DMFT, DT, and MT,

respectively The adjusted ORs for the association

between the normative treatment of malocclusion and

the CS Child-OIDP attributed to malocclusion ranged

from 2.5 (midline shift) to 8.8 (crowding)

Table 5 shows the sample distributions according to

the generic Child-OIDP and CS Child-OIDP scores for

dental caries, periodontal problems, and malocclusion

The overall scores and the prevalence scores for oral

impact were significantly lower when the CS Child-OIDP

was used than when the generic Child-OIDP was used

Discussion

The assessment of OHRQoL in children is a relatively recent initiative and CS measures are yet to be applied [30-32] Because of the plethora of oral conditions that affect the quality of children’s lives, the issue of describ-ing the CS impact has remained a challenge [1] This study assessed for the first time the discriminative ability

of the generic Child-OIDP across various socio-cultural contexts in Tanzania, and compared the discriminative abilities of the generic and CS Child-OIDP inventories with respect to normative treatment needs

About half the school children in Arusha reported experience with any oral impacts on daily performances This rate is higher than those reported previously in similarly aged groups of Tanzanian school children, but lower than those observed in Uganda and other devel-oping countries [33-35] Not unexpectedly, the younger primary school children in Dar es Salaam had less caries experience and a lower prevalence of impacts as assessed by the generic Child-OIDP than their older counterparts in Arusha Nevertheless, the performance

of the generic Child-OIDP inventory in distinguishing between subjects with and without dental caries and periodontal problems did not vary across the study sites

Table 3 Generic Child-OIDP in children from Dar es Salaam with and without various types of normative treatment needs

Mean OIDP (SD) Effect size§ OIDP > 0% (n) OIDP = 0% (n) Adjusted OR (95% CI) Dental caries

Periodontal

Plaque: good (PL score < 0.7) 0.5 (1.1) 24.8 (184) 75.2 (557) 1

Plaque: poor (PL score ≥ 0.7) 0.7 (1.3)** 0.2 31.9 (174)** 68.1 (586) 1.3 (1.1-1.7) a

Calculus: good (calc < 0.7) 0.6 (1.2) 28.1 (396) 71.9 (1012) 1

Calculus: poor (calc score ≥ 0.7) 0.7 (1.4) 0.1 32.1 (62) 67.9 (131) 1.2 (0.8-1.6) a

Malocclusion

SMO = 0 (at least one malocclusion diagnosed) 0.6 (1.3) 27.4 (155) 72.6 (411) 1

SMO > 0 (more than one malocclusion diagnosed) 0.6 (1.3) 0.01 29.3 (303) 70.7 (732) 1.1 (0.8-1.1)a

Open bite ≥ 2 mm 0.7 (1.3) 0.1 30.0 (77) 70.0 (180) 1.1 (0.8-1.5)a

Maxill overjet: ≥ 5 mm 0.5 (1.2) 0.1 22.7 (42) 77.3 (143) 0.7 (0.4-1.0)a

Mand overjet: > 0 mm 0.6 (1.3) 0.0 28.9 (39) 71.1 (96) 1.0 (0.7-1.5)a

Midline shift: ≥ 2 mm 0.7 (1.3) 0.1 30.5 (110) 69.5 (251) 1.1 (0.8-1.4) a

Crowding: present 0.6 (1.2) 0.0 29.8 (67) 70.2 (158) 1.0 (0.7-1.4) a

a

Adjusted for study site and socio-demographic factors, such as age, sex, residence, and religion

**P < 0.001, *P < 0.05

§

Effect size of mean differences

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Both the overall means and the generic prevalence

scores revealed that oral problems had a greater impact

on children suffering caries and periodontal problems

than on their counterparts without these problems This

supports the construct validity of the Child-OIDP when

used in Tanzanian school children Although the generic

Child-OIDP scores are less comparable to the specific normative treatment needs for dental caries and period-ontal problems, the positive association observed might

be explained by inferring that dental caries and period-ontal problems contribute greatly to the burden of oral impacts on children’s quality of life In a previous study,

Table 4 CS Child-OIDP scores for dental caries, periodontal disease, and malocclusion in children from Dar es Salaam with and without various types of treatment needs

Mean CS OIDP (SD) Effect size§ OIDP > 0% (n) OIDP = 0% (n) Adjusted OR (95% CI) Dental caries

DMFT > 0 0.7 (1.2)** 0.8 31.3 (110)** 68.8 (242) 5.4 (3.9-7.3)a

DT > 0 0.7 (1.3)** 0.7 32.3 (84)** 67.7 (176) 4.7 (3.4-6.5) a

MT > 0 0.7 (1.3)** 0.7 34.0 (54)** 66.0 (105) 4.2 (2.9-6.2) a

Periodontal

OHI-S ≥ 1.0 (poor) 0.4 (0.9) 14.2 (78) 85.8 (471) 0.9 (0.7-1.3) a

Plaque: good (PL < 0.7) 0.2 (0.8) 13.0 (96) 87.0 (645) 1

Plaque: poor (PL ≥ 0.7) 0.4 (1.0)* 0.1 15.1 (130) 1.2 (0.8-1.2) a

Calculus: good (calc < 0.7) 0.3 (0.8) 14.1 (198) 85.9 (1210) 1

Calculus: poor (calc ≥ 0.7) 0.4 (1.0) 14.5 (28) 85.5 (165) 0.6 (0.1-1.5)a

SMO = 0 (at least one malocclusion diagnosed) 0.01 (0.2) 0.4 (2) 99.6 (564) 1

SMO > 0 (more than one malocclusion diagnosed) 0.07 (0.5)* 0.1 3.6 (37)** 96.4 (998) 10.9 (2.6-45.8)a

Open bite: ≥ 2 mm 0.07 (0.4) 0.1 3.9 (10) 96.1 (247) 1.9 (1.0-4.0)a

Maxill overjet: ≥ 5 mm 0.2 (0.6)** 0.3 7.0 (13)** 93.0 (172) 5.4 (2.5-11.6) a

Mand overjet: > 0 mm 0.2 (0.6)* 0.2 6.7 (9)* 93.3 (126) 3.2 (1.5-7.1) a

Midline shift: ≥ 2 mm 0.09 (0.5)** 0.1 4.4 (16)* 95.6 (345) 2.5 (1.3-4.9) a

Crowding: present 0.2 (0.7)** 0.5 9.8 (22)** 90.2 (203) 8.8 (4.5-16.9) a

a

Adjusted OR for study site and socio-demographic factors, such as age, sex, residence, and religion

**P < 0.001, *P < 0.05

§

Effect size of mean differences

Table 5 Dar es Salaam sample distribution by generic OIDP and CS OIDP scores for dental caries, periodontal disease, and malocclusion

Indicator Generic OIDP CS OIDP caries CS OIDP periodontal disease CS OIDP malocclusion

Prevalence of impact (OIDP > 0)

a Cochran’s Q P < 0.001

b

Friedman P < 0.001

Trang 8

toothache was recognized as the main cause of six of

eight performance impacts of school children in

Kinon-doni district and four of eight impacts of school children

in Temeke district, in Dar es Salaam [13] A mouth

ulcer and bleeding and swollen gums were among the

causes most frequently listed by those school children

[13] Studies conducted elsewhere have shown similar

results Oral conditions related to dental caries, such as

toothache and sensitive teeth, had the greatest reported

impact on the quality of life in 11-12-year-old children

from developing countries [13,36] Despite differences in

the prevalence of Child-OIDP and in the modes of

administering the inventory across the study sites,

neither the discriminative capacity of the generic

instru-ment with respect to dental caries and periodontal

pro-blems nor its internal consistency (reliability) varied

across the study sites Previous studies that compared

self- and interviewer-administered Child-OIDP

inven-tories in the same study group found that the

instru-ment showed acceptable psychometric properties

irrespective of the mode of its administration [37,38]

As shown in Table 3, 4 and 5, the prevalence of oral

impact obtained with the generic Child-OIDP was

higher than that obtained with the CS Child-OIDP

Both the generic and CS Child-OIDP rates were

rela-tively low compared with those obtained in children

using other OHRQoL instruments This might be

attri-butable to the fact that the ultimate impacts assessed by

OIDP are rare in most study populations [30] From the

overall mean scores and the prevalence scores, both the

generic and CS Child-OIDP inventories indicated that

children with caries, periodontal problems, or

malocclu-sion experienced a greater oral impact than those

with-out these conditions This corroborates previous studies

that showed that children suffering from various dental

diseases and clinical symptoms have a poorer OHRQoL

[13,33] Using the thresholds defined by Cohen [29], the

effect sizes for the generic Child-OIDP were small when

children with normative treatment needs for dental

car-ies and periodontal problems were compared with those

without such treatment needs, and were almost

negligi-ble when children with and without orthodontic

treat-ment needs were compared In contrast, the effect sizes

related to the mean differences in the CS Child-OIDP

scores were negligible when children with and without

periodontal problems were compared, moderate when

children with and without malocclusion were compared,

and large when children with and without dental caries

were compared The present findings agree with those

of previous studies [6,14], indicating that the two forms

of the Child-OIDP are complementary rather than

alter-native sources of information Nevertheless, the CS

OIDP was better suited than the generic

Child-OIDP to identifying school children according to their

normative treatment needs for malocclusion and dental caries When assessing the strength of the association between the clinical indicators and the prevalence of oral impact, the ORs were larger when the CS Child-OIDP attributed to dental caries and malocclusion was used than when the generic Child-OIDP was used, even after adjustments were made for socio-demographic fac-tors (Tables 3 and 4) This finding corroborates some previous studies but is inconsistent with others A recent study of Thai school children revealed that the generic and CS Child-OIDP inventories distinguished equally well the groups with and without normative treatment needs for dental caries [14] Comparing the generic and CS Child-OIDP assessments of malocclu-sion in Brazilian adolescents, Bernabé [6] found that both inventories were able to discriminate between sub-jects with and without treatment needs However, the

CS Child-OIDP showed the largest effect size and there-fore appeared to be the form best able to differentiate between groups of adolescents Other studies have com-pared the discriminative abilities of generic HRQoL and OHRQoL instruments with respect to early childhood caries and found that the latter oral-specific instruments discriminated the clinical groups more efficiently [8]

It should be noted that the two study groups consid-ered were not age and sex matched, nor were they comparable with respect to their other socio-demo-graphic characteristics (Table 1) The age and sex dis-tributions of the school children with and without dental caries, periodontal problems, and malocclusions also differed, and might therefore have confounded the associations between the normative treatment needs or clinical indicators and the prevalence of oral impacts Most of the confounding effects were probably accounted for when the site-specific multivariable ana-lysis was adjusted for age, sex, and other socio-demo-graphic factors A comparison of the sample characteristics of the Dar es Salaam participants with the corresponding child population statistic on markers

of gender and parental education suggested that this sample was representative of the populations of chil-dren aged 12-14 years in the two districts investigated

No similar analysis of the school children in Arusha was performed Although both samples were rando-mized cluster samples, the possibility of selection bias cannot be overlooked The structured self- and inter-viewer-administered questionnaires used in this study had certain limitations, with bias attributed to social desirability, acquiescence, and lack of recall frequently encountered, particularly in the younger age groups [39] Attempts were made to minimize these biases by informing the participants at both sites that their responses were confidential and that no-one could link their names to their responses The estimates

Trang 9

pertaining to the school children in Dar es Salaam

might have been underestimated because social

desir-ability bias is more pronounced with interviews than

with self-administered questionnaires Because the

Child-OIDP was used as an interviewer-administered

measure in Dar es Salaam, whereas the inventory was

self-administered in Arusha, the comparability of the

data collected across sites could be questioned

[12,31,32] Nevertheless, previous studies of children

from the general population and from specific disease

groups have supported the comparability of the two

modes of administration of the Child-OIDP inventory

[6,14]

Conclusion

The generic Child-OIDP discriminated equally well

between children with and without dental caries and

periodontal problems across socio-culturally different

study sites in Tanzania Compared with its generic form,

the CS Child-OIDP discriminated more effectively

between children with and without dental caries or

mal-occlusion Thus, the CS Child-OIDP seemed to be

bet-ter suited to support the clinical indicators of dental

caries and malocclusion when the oral health needs of

school children are estimated

Acknowledgements

The work in Arusha was partly funded by a grant from the Norwegian

Cooperation Programme for Development, Research and Education (NUFU),

and partly by the Faculty of Medicine and Dentistry, University of Bergen It

was facilitated by the collaborating institutions: Muhimbili University of

Health and Allied Sciences and the Centre for Educational Development in

Health, Arusha, Tanzania, and the Universities of Oslo and Bergen, Norway.

The authors acknowledge and thank the Arusha municipality, Arusha rural

and Meru administrative council authorities, Muhimbili University of Health

and Allied Sciences, the Ministries of Health and Social Welfare and

Education of Tanzania, and REK Vest of Norway for their permission to

conduct the study The authors are indebted to the study participants, their

parents, and their school administrations for making this study a reality We

thank Mrs Flora Mrita for her diligent assistance during the clinical field

work.

Author details

1 Department of Clinical Dentistry, Community Dentistry, University of Bergen,

Bergen, Norway 2 Centre for International Health, University of Bergen,

Bergen, Norway 3 Muhimbili University of Health and Allied Sciences, Dar Es

Salaam, Tanzania 4 Department of Clinical Dentistry-Orthodontics, University

of Bergen, Bergen, Norway.

Authors ’ contributions

HSM: principal investigator, designed the study, collected the data (Arusha

study site), performed the statistical analyses, and wrote the manuscript MT:

investigated, designed, and collected the data at the Dar es Salaam site.

JRM: participated in the design of the study and provided valuable guidance

in the data collection at both sites, and has been actively involved in writing

the manuscript PD: supervised, designed, and provided guidance for the

study at the Dar es Salaam site ANÅ: main supervisor, designed the study,

and guided the statistical analyses All authors have read and approved the

final manuscript.

Competing interests

The authors declare that they have no competing interests.

Received: 19 January 2011 Accepted: 26 May 2011 Published: 26 May 2011

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Pre-publication history

The pre-publication history for this paper can be accessed here:

http://www.biomedcentral.com/1471-2431/11/45/prepub

doi:10.1186/1471-2431-11-45

Cite this article as: Mbawalla et al.: Discriminative ability of the generic

and condition-specific Child-Oral Impacts on Daily Performances

(Child-OIDP) by the Limpopo-Arusha School Health (LASH) Project: A

cross-sectional study BMC Pediatrics 2011 11:45.

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