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A pilot and feasibility study of a cognitive behavioural therapy-based anxiety prevention programme for junior high school students in Japan: A quasi-experimental study

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There is a good deal of evidence that cognitive behavioural therapy is effective for children and adolescents with anxiety-related problems. In Japan, an anxiety prevention programme based on cognitive behavioural therapy called ‘Journey of the Brave’ has been developed, and it has been demonstrated to be effective for elementary school students (aged 10–11 years).

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RESEARCH ARTICLE

A pilot and feasibility study of a cognitive

behavioural therapy-based anxiety prevention programme for junior high school students

in Japan: a quasi-experimental study

Ikuyo Ohira1,2* , Yuko Urao1,2, Yasunori Sato3, Toshiyuki Ohtani1,4 and Eiji Shimizu1,2,5

Abstract

Background: There is a good deal of evidence that cognitive behavioural therapy is effective for children and

ado-lescents with anxiety-related problems In Japan, an anxiety prevention programme based on cognitive behavioural therapy called ‘Journey of the Brave’ has been developed, and it has been demonstrated to be effective for elementary school students (aged 10–11 years) The purpose of this study was to have classroom teachers deliver the programme

to junior high school students (aged 12–13 years) and to test the feasibility and efficacy of the programme in this setting

Methods: This study was a prospective observational study and was approved by the Chiba University Review Board

An intervention group consisting of six classes of students in their first year of junior high school at two different

schools (n = 149; 81 boys, 68 girls) received seven 50-min programme sessions Participants in the control group were recruited from four classes of students in their second year of junior high school at one school (n = 89; 51 boys, 38

girls) All participants completed the Spence Children’s Anxiety Scale at pre-test, post-test, and 2–3 month follow-up Statistical analysis was conducted using a mixed-effects model for repeated measures model

Results: Mean total anxiety scores indicated a non-significant decrease at the 2–3 month follow-up for the

interven-tion group compared to the control group The group differences on the SCAS from baseline to post-test was − 71

(95% CI − 2.48 to 1.06, p = 43), and the 2–3 month follow-up was − 49 (95% CI − 2.60 to 1.61, p = 64).

Conclusions: In this pilot study, implementation of the programme confirmed the partial feasibility of the

pro-gramme but did not elicit a significant reduction in anxiety scores In addition, there are several methodological limitations to this study In the future, we propose to test the feasibility and efficacy of the programme with the required sample size and by comparing groups with equal characteristics as well as by carrying out additional

follow-up assessments

Trial registration UMIN000032517.

Keywords: Anxiety, Prevention, Cognitive behavioural therapy, Junior high school, Universal, Japan

© The Author(s) 2019 This article is distributed under the terms of the Creative Commons Attribution 4.0 International License ( http://creativecommons.org/licenses/by/4.0/ ), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/ publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

Open Access

*Correspondence: sunny133888@gmail.com

1 United Graduate School of Child Development, Osaka University,

Kanazawa University, Hamamatsu University School of Medicine,

Chiba University and University of Fukui, 2-2 Yamadaoka, Suita-shi,

Osaka 565-0871, Japan

Full list of author information is available at the end of the article

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Anxiety disorders are one of the most common types of

psychiatric disorder [1], with the lifetime prevalence of

any anxiety disorder in children and adolescents ranging

from 8.8 to 31.9% The average age of onset for anxiety

disorders is 11 years [2], and such disorders are likely to

become chronic [3] It is believed that anxiety often leads

to depression; for example, according to the results of a

follow-up survey conducted 10  years after a

longitudi-nal study of anxiety and depressive disorders in

adoles-cents, anxiety disorder in adolescents is associated with

a relatively high risk of anxiety or depressive disorders in

adulthood [4] In Japan, a study examining the

relation-ship between anxiety and depression among junior high

school students found a significant longitudinal

relation-ship between these disorders after 3  months [5] Thus,

the symptoms of many anxiety disorders are chronic, and

anxiety has been found to increase the risk of depression

and other psychiatric disorders

Anxiety disorders in children and adolescents

inter-fere with their school life; for example, it has been

shown that they result in school refusal and a decline in

academic performance [6 7] The results of a previous

study of school refusal among adolescents indicate that

this is often caused by anxiety disorders Anxiety

disor-ders are observed in approximately 50% of individuals in

representative samples of clinic-referred youth

exhibit-ing school refusal [8] Particularly, in Japan, it has been

pointed out that the problem of school refusal is strongly

related to anxiety According to a survey conducted by

the Ministry of Education, Culture, Sports, Science and

Technology in 2017 [9], the number of school

refus-als among elementary and junior high school students

is more than 140,000, representing a higher proportion

of the population than previously seen It has also been

reported that the proportion of students with tendencies

to anxiety is up to 33.2%, which is a contributing factor to

this state of affairs

The relationship between anxiety and academic

achievement has also been studied In recent years,

the relationship between developmental disorders and

school maladaptation has attracted much attention;

how-ever, there is a possibility that children and adolescents

who have difficulty concentrating or paying attention in

school as a result of anxiety problems tend to be

misdi-agnosed as having attention deficit hyperactivity

disor-der (ADHD) [10] Furthermore, it has also been pointed

out that children diagnosed with a learning disability

or ADHD include those who show poor performance

because of high anxiety [11] As mentioned above, it

has been shown that anxiety problems among children

and adolescents cause maladaptation to school life, and

in turn, this maladaptation may later become a factor

in other comorbidities, such as anxiety disorders and depression Therefore, it is important to provide early preventive interventions for children and adolescents with the aim of preventing anxiety problems

Although support during adolescence is regarded as important, many adolescents who have anxiety do not receive appropriate support [12] In addition, in many cases, it takes a considerable amount of time for patients

to begin receiving treatment after the onset of a disorder [13] A lack of knowledge about mental health and the stigma attached to mental health problems are consid-ered factors in this delay in obtaining support; acquiring accurate knowledge about mental health in school classes

is effective in preventing such delays [14] Puberty, also referred to as ‘the second birth’ [15], is regarded as a developmental stage during which individuals are par-ticularly sensitive to others’ evaluations of them, in addi-tion to being a period of remarkable mental and physical development; thus, it is also a period during which vari-ous emotional and behavioural problems become more likely [16] It is reported that adolescents may present with more severe forms of anxiety-based school refusal than do younger children, and in adolescents, this is also more frequently associated with depressive disorders [17] It is clear that the presence of an anxiety disorder

in this age group is a high-risk factor for serious mental health problems, and support must be offered to children and adolescents in an effective and accessible form [18] Cognitive behavioural therapy (CBT) is an evidence-based psychological treatment method that can alleviate and improve emotional problems such as anxiety and depression School-based treatment programmes based

on CBT for anxiety, depression, and other problems in children have been found to be effective in randomised controlled trials [19] Furthermore, attention has been paid to a CBT-based approach to anxiety prevention, which has been found to be effective when delivered in schools [20]

Preventive interventions for mental disorders are clas-sified into three levels by the Institute of Medicine (IOM): (1) universal interventions, (2) selective interventions, and (3) indicated interventions [21] Universal interven-tions target the whole population, including those who have no symptoms of the relevant disorder Selective interventions target individuals or groups who are at a higher than average risk Lastly, indicated interventions target individuals or groups who are already experiencing

a low-to-moderate level of symptoms, and therefore, are

at a high risk of developing the disorder in the future For students, school is a natural and familiar place, and the implementation of a universal prevention programme

in schools enables students to receive treatment more easily in terms of time, place, and cost, and may provide

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them with skills and strategies that help prevent or delay

the onset of mental disorders [22–24] Therefore, it can

be argued that it is of great importance to implement a

universal prevention programme to prevent future

anxi-ety disorders and to reduce the risk of comorbidity, even

in children without particular symptoms or signs at the

time of the intervention Although the delivery of a

men-tal health programme in school by class teachers has

an especially low cost, which makes continued

imple-mentation of such a programme possible, the results of

a randomised controlled trial of a universal prevention

programme for anxiety in school did not demonstrate

the effectiveness of the teacher’s conduct [25]; however,

other randomised controlled trials have found that in the

trauma-focused group intervention ‘Mein Weg’ for young

refugees, lay counsellors’ conduct in a psychosocial

intervention was effective [26, 27] As mentioned above,

numerous benefits of implementing the programme at

the school exist, and we believe that it would be

benefi-cial for the teacher to participate in this programme

‘Friends’ is a universal programme aimed at preventing

childhood and adolescent anxiety [28] This programme

has been shown to be effective in adolescents (aged

14–16 years), although the effect of the intervention on

this group is small compared to its effect on younger

chil-dren (aged 9–10 years) [29] However, implementation of

the ‘Friends’ programme in Japan did not lead to a

sig-nificant reduction in total anxiety scores [30] Therefore,

it might be effective to apply a programme developed

according to the social and cultural background of Japan

In Japan, a CBT-based anxiety prevention programme

called ‘Journey of the Brave’ that can be implemented as

part of the Japanese school curriculum has been

devel-oped [31] In a previous study on fifth year elementary

school students (intervention group n = 41, control group

n = 31), trained health facilitators (with graduate school

training in CBT) conducted 10 sessions in the

class-room as a school lesson [32] The mean anxiety score on

the SCAS for the intervention group had significantly

reduced at both post intervention and the 3-month

fol-low-up compared to the control group

Although research into this topic targeting junior high

school students have not so far been conducted in Japan,

we believe that it is important to tackle potential mental

health problems in junior high school students, given that

as described above, they may face an ‘adolescent crisis’ at

a mentally and physically sensitive stage of their life

Furthermore, in Japan, the first year of junior high

school is also the year in which students experience

major changes in their educational environment First,

as multiple elementary schools feed into each junior

high school, the school and its classes are larger in size,

and students experience major changes in their peer

relationships Second, elementary school and junior high school differ greatly in terms of the student–teacher rela-tionship In elementary school, the so-called ‘home room teacher’ system is applied, while the junior high school follows the curriculum management system (different areas of the curriculum are taught by specialised teach-ers) Finally, the number of subjects and the degree of learning difficulty increase In addition to experiencing such environmental changes, researchers have pointed out that junior high school students are also approach-ing a sensitive stage of adolescence, durapproach-ing which various psychological and behavioural problems may come to the surface [33]

The ‘Journey of the Brave’ programme was originally developed for children in the fourth to sixth year of elementary school However, because the programme was designed based on evidence-based CBT theory and tackles ways to cope with anxiety in interpersonal rela-tionships, it seems likely that this programme could

be adapted for use among junior high school students Therefore, in this pilot study, we aimed to implement this programme among junior high school students, with the classroom teacher acting as a facilitator, and to test its feasibility and efficacy with the aim of preventing anxiety problems

Methods

Study design and participants

This study was conducted in collaboration with Chiba University and Kodomo Minna Project (‘Project for all the children’) This is a project in which ten universities collaborated and conducted a research, commissioned by the Ministry of Education, Culture, Sports, Science and Technology, for the purpose of improving school refusal and bullying, which are major issues in Japanese schools This is part of a research project on students from ele-mentary to high school In this study, data on junior high school students were collected and analysed The Minis-try of Education, Culture, Sports, Science and Technol-ogy recruited schools to participate in this programme The Board of Education of a prefecture located in the western part of Japan applied to participate, and students

in their first year of junior high school were selected to participate in the programme Although it would have been desirable methodologically to recruit a control group from students in the same year, the Board of Edu-cation made a firm request for all first-year students in the participating schools to receive the programme at the same time; therefore, students in their second year of junior high school were recruited for the control group This was a universal quasi-experimental study with an intervention and a control group The participants in the study were 472 students in their first or second year of

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junior high school (aged 12–14  years), attending three

public junior high schools in a single prefecture in Japan

Intervention group participants received the anxiety

prevention programme, and control group participants

received no prevention programme

In addition, the ‘Journey of the Brave’ programme was

conducted as part of regular classes in schools This study

was a prospective observational study that collected and

analysed students’ anxiety scores before and after the

programme It was approved by the Chiba University

Review Board In this study, consent was obtained in the

form of an opt-out Parents were given an informational

letter about the study, and they could provide opt-out

consent to exclude their child from participation In

addi-tion, at the time of the survey, teachers distributed a

writ-ten assent form for the students, for students to provide

their assent to participate

Prevention programme: ‘Journey of the Brave’

Table 1 provides a summary of the ‘Journey of the

Brave’ programme This is a programme developed with

consideration for the psychological characteristics of

children and adolescents and for the social and cultural

background of Japan, with the following three

repre-sentative features [31] First, this programme

special-ises in the prevention of anxiety-related problems, to

help children and adolescents understand the purpose

of the programme and engage in effective learning

Second, in order to enable children and adolescents to

enjoy the programme, likeable characters are presented

in a story format Third, group work is intentionally

avoided in favour of emphasising an individual work

format because of the psychological characteristics of

Japanese adolescents It has been pointed out that

com-pared to individuals in Western countries, Japanese

individuals tend to be more influenced by the way they

are perceived by others [34] Adolescents tend to feel more anxious about the relationships within the same age group [35], and it is necessary to consider that there may be some students with high anxiety in the class This programme consists of ten 45-min sessions; the content is taught according to a workbook and a teacher’s manual The first half of the programme is dedicated to the development of ‘anxiety hierarchy’ and the experience of gradual exposure, while the sec-ond half mainly concerns cognitive restructuring More precisely, after psychological education on anxious feelings (i.e., the notion that anxiety is a natural feel-ing that everybody has and plays an important role in protecting you from danger, but if excessive anxiety persists, it might lead to disturbances in life, etc.), each student is encouraged to establish his or her own goal for the programme, such as giving a presentation in front of all the students, an important test, and so on

In stage 3, relaxation skills such as breathing methods and muscle relaxation are taught In stage 4, students develop a table of their ‘anxiety hierarchy’, consisting

of 7 steps that will allow them to reach the goal set in stage 2 Stages 5, 6, and 7 encompass the process of gradually learning about the cognitive model (the rela-tionship between cognition, behaviour, emotion, and bodily responses) as well as cognitive restructuring

At the same time, gradual exposure homework is given

to address higher levels of anxiety in accordance with the anxiety stairs table developed in stage 4 Assertion skills to reduce interpersonal anxiety are taught in stage 8; stage 9 consists of an overall review session; and stage 10 involves a summary and graduation ceremony

In the workbook used by the students, realistic exam-ples of many anxiety-provoking moments in their daily lives are provided so that they can deepen their under-standing of anxious feelings and CBT

Table 1 Contents of ‘Journey of the Brave’ by session

Session at the junior high school Original session Content of ‘Journey of the Brave’

6 Identifying cognitive distortions and coping with rumination

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The original ‘Journey of the Brave’ programme consisted

of 10 sessions (administered once per week, each lasting

45 min) As this study conducted the programme in

jun-ior high schools, the research group elected to reduce the

number of sessions in view of the fact that the length of

class time was 5 min longer than in elementary school,

and that junior high school students should be able learn

more quickly In addition, since the curriculum of the

regular classes for the year has already been determined,

the Board of Education requested that the number of

classes be reduced to seven that were administered about

once per week and lasting 50 min

In this programme, the content of each session was

based on CBT theory (Table  1), but the relaxation

method (Stage 3) could be shortened as it was addressed

in health class, and Stages 2 and 3 were consolidated into

one session The remaining content was implemented

within the 7 class hours As Stages 5 and 6 as well as

Stages 9 and 10 had little individual work for students, we

decided to summarize these in one session

Additionally, the following three things were addressed

as we utilized a group of practitioners who did not have

specialized knowledge about CBT to allow them to lead

this programme smoothly and effectively First, we

con-ducted a 6-h workshop, which was a training course This

training course was a free workshop, and participants

received a certificate of completion This workshop

con-sists of lectures on the theory of CBT, role-plays for each

session (lasting about 20 min per session), feedback from

instructors, and time for questions and answers

Sec-ond, we devised a workbook with detailed contents that

allowed the students to read and understand it

them-selves Third, we had them utilize a teacher’s manual,

which was distributed to the teachers The teacher’s

man-ual was attached with the Q & A and information on how

to proceed with the class, which was created based on

questions by teachers in past programmes In addition,

after the completion of stage 3, a template for reporting

the progress of the class was attached to the teacher’s

manual In the report template, there is a field for

com-ments and consultations for supervision In addition, if

the teachers wanted to have a consultation, they could do

so at any time by phone or email during the intervention

period This was described in the manual and shared with

the teachers at the workshop

The preventive interventions were conducted from

September to November 2017 in one participating school

and from October to December 2017 in the other In each

case, the intervention was delivered by the class teacher,

who had taken the ‘Journey of the Brave’ programme

instructor training course In total, the programme was

implemented by the class teacher in six classes of two junior high schools

All sessions were held in the classroom during regular class time Every session was conducted according to the workbook and the teacher’s manual, and a piece of home-work was to be assigned at the end of each session, to be worked on at home and returned by the next session, in order to help students consolidate the content Students

in the control group followed the regular school curricu-lum The main assessments were a pre-test (Time 1; base-line), a post-test (Time 2; 2–3 months after basebase-line), and

a follow-up test (Time 3; 2–3 months after the post-test)

At each of these time points, self-report questionnaires were distributed to the students by the teacher in charge

of each class, and all students (149 in the intervention group and 89 in the control group) completed the ques-tionnaires The teachers assisted students in this process

by reading the questions aloud

Measurements

Primary outcome measure: Spence Children’s Anxiety Scale

The Spence Children’s Anxiety Scale (SCAS) [36] is a self-report measure of anxiety symptoms designed for children and adolescents The scale consists of 38 items relating to anxiety symptoms, divided into six subcat-egories: separation anxiety, social phobia, panic disorder/ agoraphobia, generalised anxiety disorder, fear of physi-cal injury, and obsessive–compulsive disorder Possible

item scores range between 0 (never) and 3 (always), and

the maximum possible score is 114 Ishikawa et al [37] developed a Japanese version of the SCAS with good internal reliability coefficients According to a previous study, the average SCAS score among 7- to 19-year-old

children and adolescents is 18.11 (SD = 12.87), and the

cut-off point is 35 [38]

Secondary outcome measure: Emotion‑Regulation Skills Questionnaire

The Emotion-Regulation Skills Questionnaire (ERSQ) [39] is a self-report questionnaire consisting of 27 items

Possible item scores range between 0 (not at all) and 4 (almost always), and the maximum possible score for

the questionnaire is 108 In the original version, success-ful application of emotion-regulation skills is assessed through the following nine subscales: awareness, sensa-tion, clarity, understanding, modificasensa-tion, acceptance, tolerance, readiness to confront, and compassionate self-support Fujisato et  al [40] developed a Japanese version of the ERSQ with good internal reliability coeffi-cients In the Japanese version, items are divided into two subcategories: acceptance and engagement (tolerance, modification, readiness to confront, and acceptance)

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and awareness and understanding (sensation, awareness,

understanding, clarity, and compassionate self-support)

Programme evaluation form for students

Students were asked to evaluate the programme after

completing all seven sessions An evaluation form was

used to measure their acceptance of and satisfaction with

the programme The form comprised the following two

sections: (1) the student’s evaluations of the content of

the programme (5 items; for example, ‘Do you think that

this programme helped you to cope well with your

feel-ings of anxiety?’ with each item scored from 0 = disagree

to 3 = agree; see Additional file 1: Table S1) and (2) the

student’s accomplishment of their ‘anxiety hierarchy’ task

(scored from 0 = none to 3 = complete).

Statistical analysis

For baseline variables, summary statistics are presented

in the form of frequencies and proportions for

categori-cal data, and means and SDs for continuous variables

Analysis of the primary outcome measure consisted of

a mixed-effects model for repeated measures (MMRM),

with intervention group, time, and the interaction

between intervention group and time as fixed effects; an

unstructured covariate was used to model the

covari-ance of within-participant variability MMRM analysis

assumes that any missing data occur randomly Analysis

of the secondary outcome measure was performed in the

same manner We also conducted subgroup analysis by

comparing the intervention and control groups on their

SCAS scores in a high-anxiety subgroup (SCAS score of

35 points or above in the pre-test) and a low-anxiety

sub-group (SCAS score below 35 in the pre-test) Subsub-group

analysis was also performed in the same manner

Additionally, the responses to the students’ evaluation

questionnaires were aggregated A repeated-measures

analysis of variance (ANOVA) was conducted to examine

the changes in SCAS scores at each time point according

to the students’ responses regarding the extent to which

they had accomplished their ‘anxiety hierarchy’ task

(0 = none to 3 = complete)

All comparisons were planned and all p values reported

are two-tailed A p value < 05 was considered to

repre-sent statistical significance All statistical analyses were

performed using the SAS software program, version 9.4

(SAS Institute, Cary, NC, U.S.A.), and SPSS Version 24.0

(IBM, Armonk, New York, USA)

Results

Three schools agreed to participate in this study, but

one was excluded from participation before the

base-line assessments because it could not deliver the full

programme during the requisite school year As a result

of confirming parental consent and the student’s par-ticipation in this research, five parents in intervention group and five parents in control group did not provide consent All students assented to participate Thus 253

of 263 eligible students at two junior high schools had valid consent to participate The intervention group consisted of first-year students (aged 12–13  years) in six classes of two junior high schools The control group consisted of second-year students (aged 13–14 years) in four classes of one junior high school The final number

of participants entered into the analysis was 149 in the intervention group (81 boys, 68 girls) and 89 in the con-trol group (51 boys, 38 girls; Fig. 1)

Pearson’s correlation coefficient indicated that there was a weak negative correlation between SCAS and

ERSQ scores at pre-test, r = − 19, p < 001 Next, the

intervention group and control group were tested for differences in gender ratio at pre-test using the Chi squared test There was no significant difference

(p = 66) Finally, t tests were conducted to compare the

groups at baseline on their pre-test SCAS and ERSQ scores The intervention group exhibited higher SCAS

scores than those of the control group (p = 02)

How-ever, there were no significant differences in ERSQ

scores between the two groups (p = 61).

Tables 2 3 4 present the results of the MMRM analy-sis of the intervention and control groups’ SCAS and ERSQ scores at each time point In the primary analysis

of SCAS scores, the estimated mean changes in SCAS score between baseline and follow-up according to the model were − 2.20 (95% CI − 3.49 to − 91) and − 1.70 (95% CI − 3.37 to − 05) for the intervention and con-trol groups, respectively; the difference between groups

was − 49 (95% CI − 2.60 to 1.61, p = 64; Table 2)

In the secondary analysis, the estimated mean changes in ERSQ score between baseline and

follow-up according to the model were 2.13 (95% CI − 15

to 4.41) and 61 (95% CI − 2.20 to 3.42) for the inter-vention and control groups, respectively; the differ-ence between groups was 1.52 (95% CI − 2.10 to 5.14,

p = 41; Table 3)

In the subgroup analysis of the high-anxiety group (SCAS scores ≥ 35), the estimated mean changes in SCAS score between baseline and follow-up according to the model were − 3.81 (95% CI − 8.25 to 63) and 89 (95% CI

− 6.04 to 7.82) for the intervention and control groups, respectively; the difference between groups was − 4.70

(95% CI − 13.02 to 3.62, p = 26; Table 4) Additionally,

in the subgroup analysis of the low-anxiety group (SCAS scores < 35), the estimated mean changes in SCAS score between baseline and follow-up according to the model were − 1.94 (95% CI − 3.26 to − 62) and − 2.03 (95% CI

− 3.70 to − 36) for the intervention and control groups,

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respectively; the difference between groups was 09 (95%

CI − 2.05 to 2.22, p = 94; Table 4)

Students’ programme evaluations

Additional file 1: Table S1 presents the number and

per-centage of respondents giving each response to each

item on the programme efficacy section of the evaluation questionnaire

According to the repeated-measures ANOVA to exam-ine SCAS scores at each time point based on students’ responses regarding the extent to which they had accom-plished their ‘anxiety hierarchy’ task (Table 5), there was

Enrollment 3 Schools Enrolled (n = 472)

Excluded

• 1 School (n = 209)

6 classes allocated to intervention (n = 162)

• Received child assent and parental

consent (n = 157)

• Did not receive parental consent (n = 5)

4 classes allocated to control (n = 101)

• Received child assent and parental

consent (n = 96)

• Did not receive parental consent (n = 5)

Non-Random Allocation

• Completed assessment (n = 147)

• Did not complete assessment (n = 2)• Did not complete assessment (n = 2) Completed assessment (n = 87)

• Completed assessment (n = 136)

• Did not complete assessment (n = 11) • Completed assessment (n = 84) • Did not complete assessment (n = 3)

T3: Follow-up

Analysed (n = 149) Analysis Analysed (n = 89)

• Completed assessment (n = 149)

• Did not complete assessment (n = 8) • Completed assessment (n = 89) • Did not complete assessment (n = 7)

T2: Post-test T1: Pre-test

Fig 1 displays the number of students at each time point and sample count of the ITT analysis ITT intention to treat

Table 2 SCAS scores over time

Estimated mean score on the SCAS at each time point and estimated difference in change between the groups according to a mixed effects model for repeated

measures Scores are presented in the form M (95% CI) SCAS Spence Children’s Anxiety Scale

(n = 149) Control group(n = 89) Between group differences for baseline change p

Pre 21.24 (18.88–23.60) 17.40 (14.39–20.42)

Follow-up 18.86 (16.49–21.23) 15.31 (12.30–18.32) − 49 (− 2.60 to 1.61) 64

Table 3 ERSQ scores over time

Estimated mean score on the ERSQ at each time point and estimated difference in change between the groups according to a mixed effects model for repeated

measures Scores are presented in the form M (95% CI) ERSQ Emotion-Regulation Skills Questionnaire

(n = 140) Control group(n = 86) Between group differences for baseline change p

Pre 57.28 (52.89–61.68) 60.95 (55.34–66.55)

Follow-up 59.27(54.85–63.68) 61.64 (56.03–67.25) 1.52 (− 2.10 to 5.14) 41

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a no significant interaction effect between group and

time (p = 85).

Discussion

In this study, we delivered the universal anxiety

preven-tion programme ‘Journey of the Brave’ to junior high

school students in Japan and tested its feasibility and

efficacy in reducing anxiety First, none of the schools

dropped out, and all seven sessions were possible within

the schools’ curriculum In addition, the results of the

students’ responses in the evaluation questionnaire

(Additional file 1: Table  S1) showed an overall positive

evaluation Thus, the feasibility of programme

imple-mentation in junior high school was partially confirmed

Next, the results indicated that there was no significant

difference between the intervention and control groups

in terms of change in SCAS scores or ERSQ scores

Fur-thermore, in a subgroup analysis, the intervention group’s

SCAS scores were not significantly reduced in either the

high-anxiety group (SCAS scores ≥ 35) or the

low-anxi-ety group (SCAS scores < 35)

In this pilot study, programme implementation did

not elicit a clear reduction in student’s anxiety, nor did

it clearly show a relationship between anxiety and emo-tional regulation skills However, there are several factors

to consider as possible reasons for the lack of reduction

in students’ anxiety in the intervention group

Student’s anxiety

The results for anxiety are in contrast to those of the original study of this preventive intervention on elemen-tary school students [32], in which a significant reduc-tion in the anxiety scores of the intervenreduc-tion group was observed We consider two possible reasons for the absence of a significant reduction in anxiety scores in the present study The first reason is that this programme was facilitated by classroom teachers with limited expertise for CBT, whereas in the original study, the programme was conducted by trained health facilitators The second

is that the environmental surroundings of junior high school students differ greatly from those of elementary school students, and the former group are at a sensitive and difficult developmental stage compared to elemen-tary school students

In the previous study with elementary school students, the programme was delivered mainly by trained health facilitators, but in the present study, the intervention was delivered by teachers In a UK-based study of the effect

of universal anxiety prevention programmes in schools,

it has been reported that intervention by trained health facilitators is effective, but that teacher-led interven-tion may not be effective [25] In this study, when class-room teachers acting as facilitators were asked about the amount of homework assigned, they reported that homework assignment and review was not practiced reg-ularly at the two schools Homework is considered one

of the most important therapeutic components of CBT [41] In CBT, the ultimate goal is for clients to be able

to exercise control over their own emotions and behav-iours, and the practice provided by homework is useful

Table 4 SCAS scores over time: subgroup

High-anxiety subgroup (SCAS scores ≥ 35), Low-anxiety (SCAS scores < 35) subgroup analysis: estimated mean score on the SCAS at each time point and estimated

difference in change between the experimental groups according to a mixed effects model for repeated measures Scores are presented in the form M (95% CI) SCAS

Spence Children’s Anxiety Scale

Pre 51.74 (46.65–56.82) 45.88 (38.04–53.72)

Post 45.80 (40.65–50.95) 46.88 (39.04–54.72) − 5.89 (− 13.71 to 1.94) 13 Follow-up 47.80 (42.47–53.14) 46.75 (38.46–55.05) − 4.70 (− 13.02 to 3.62) 26

Pre 16.76 (15.05–18.47) 13.58 (11.42–15.74)

Follow-up 14.67 (12.95–16.40) 11.81 (9.64–13.98) 09 (− 2.05 to 2.22) 94

Table 5 SCAS scores according to success in accomplishing

‘anxiety hierarchy’ task (n = 132)

SCAS scores at each time point according to the extent to which students

reported that they had succeeded in accomplishing their selected ‘anxiety

hierarchy’ exposure task Scores are presented in the form M (SD) SCAS Spence

Children’s Anxiety Scale

‘Anxiety hierarchy’ task accomplishment

(n = 15) A little(n = 52) Almost complete

(n = 56)

Complete

(n = 9)

Pre 23.87 (18.24) 22.33 (16.80) 19.34 (11.82) 14.33 (11.21)

Post 22.07 (19.27) 20.87 (15.92) 17.04 (11.30) 13.89 (13.82)

Follow-up 23.60 (20.00) 20.06 (15.93) 16.48 (12.88) 13.33 (12.53)

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in establishing knowledge and skills, making use of them

in daily life (generalisation), and improving self-efficacy

Previous studies in which this programme has been

implemented have also shown that ongoing provision

and review of homework helps students to consolidate

their knowledge and change their behaviour [32] Since

it can be presumed that the facilitator’s level of expertise

in CBT is particularly influential with regard to

home-work assignment and students’ accomplishments with

gradual exposure (reported in the present study as part

of the students’ programme evaluation questionnaires),

it is possible that differences in the expertise of

facilita-tors may have caused the disparity in effects between the

original and the present study In mental health

interven-tions delivered by lay counsellors, supervision has been

shown to be important in managing programme fidelity

[42, 43]; therefore, it will help the classes progress more

effectively if the supervision of the teachers who are

lead-ing the sessions can be enriched In this study, there were

no telephone or email consultation requests from the

teachers In addition, in the report template, the teacher

reported the completion of stage 3 and the future

sched-ule of the class at the midpoint of this programme There

was a section where comments and consultations from

teachers were entered into this report template, but there

were only comments on the programme and impressions

about the class overall, and no records of consultations

Therefore, for supervision, it will be necessary to improve

the report format so that teachers can easily complete

assignments and consultations Furthermore, in future

implementation, in addition to using the report template,

it will be important to set a time for conducting

supervi-sion sessupervi-sions in advance

In addition, the workbook used in this programme

seems to be appropriate, because it deals with themes

that are likely to present issues during adolescence, such

as anxiety in interpersonal relationships, but it is

possi-ble that the content might not have been suitapossi-ble for the

developmental stage of junior high school students

Feed-back from teachers who had been involved in delivering

this programme was collected at the end of the

interven-tion, and some teachers mentioned that ‘the illustrations

may be too childish for the students’ and ‘some examples

of anxiety scenarios don’t match the students’ level of

development’ We propose that a future task should be to

improve the content of the workbook so that it matches

the developmental stage of junior high school students

Furthermore, in the present study, the number of

ses-sions was reduced from 10 to seven in view of the fact

that junior high school students have a higher level of

understanding than elementary school students

How-ever, a meta-analysis of research on universal

school-based preventive interventions [44] shows that the

greater the number of sessions, the larger the effect; thus,

it is probable that the negative outcome in the present study may be partially attributable to this reduction of the number of sessions

We believe that the factors discussed above greatly influenced the students’ motivation for learning dur-ing this programme Therefore, it will be necessary to revise the contents of the programme further, based on the developmental stage of junior high school students and taking into account the evaluations provided by participants in the programme, and to deliver the full

10 sessions in future administrations of the preventive intervention

A final point to consider is that, in general, it is desir-able for participants in both the intervention and con-trol groups to have comparable scores on the outcome measure at baseline; however, in this study, the anxiety scale (SCAS) scores significantly differed between the groups The participants in this study were recruited from the first year (intervention group) and second year (control group) of junior high school The first year of junior high school in Japan is a year in which students experience major changes in their educational environ-ment Research has reported that school refusal and the number of students whose study motivation declines

is increasing rapidly [45] It is estimated that the first year of junior high school is a time when anxiety greatly increases compared to other grades, and the difference between the groups in this study is possibly attributable

to the fact that the groups were drawn from different academic years Additionally, the small number of par-ticipants in this study might have influenced this result The results of the original study (2018) revealed that the smaller the number of participants, the greater the dif-ference in baseline scores between the intervention and control groups In the future, we plan to verify the effi-cacy of the programme by recruiting an appropriate number of participants from the same academic year and who have comparable mean total scores on the anxiety scale (SCAS)

Students’ programme evaluations

Based on the results of the questionnaire items in which students were asked to evaluate the efficacy of the pro-gramme (item 3: ‘Do you think that this propro-gramme helped you to cope well with your feelings of anxi-ety?’ and item 5: ‘Do you think that what you learned

in this programme will be useful in the future?’), more than 70–80% of the students answered in the affirma-tive One of the advantages of implementing a univer-sal prevention programme in schools is the prevention

of potential future deterioration of the mental health

of students who do not present any symptoms or signs

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at the time of the programme, and the reduction in the

risk of other comorbidities Although no significant

reduction in participants’ SCAS scores was observed

on this occasion, we conclude that the delivery of this

programme is useful in allowing participants to acquire

knowledge and skills regarding how to manage their

anxiety, and these techniques can be used to exercise

control of their own emotions and behaviours in their

future lives By implementing this universal

interven-tion programme for anxiety preveninterven-tion in schools,

students might acquire the knowledge and skills based

on CBT and apply them to prevent mental health

dete-rioration in the future Therefore, longitudinal studies

must be conducted to verify the long-term efficacy of

universal preventive interventions [46]; doing so for

the programme implemented here, through a follow-up

assessment, is a future task

Furthermore, the results indicated that there was no

significant difference in SCAS scores at each time based

on students’ responses regarding the extent to which they

had accomplished their ‘anxiety hierarchy’ task (0 = none

to 3 = complete) However, looking at the change in

the score at each stage, we found that the students who

reported positive progress in their responses to the item

on the extent to which they were able to accomplish their

anxiety hierarchy gradual exposure task also exhibited a

decrease in SCAS scores at the post-test and follow-up

test In contrast, the scores of students who reported

that they had not been able to complete any of the steps

toward their task were reduced in the post-test, but

sub-sequently increased again in the follow-up test

As a second point, when examining total scores in the

pre-test, we noticed that the higher the participant’s

anx-iety score, the lesser the extent to which they were able

to accomplish their anxiety hierarchy task The results

of many tests of CBT treatments for anxiety problems in

children and adolescents have shown that success with

exposure therapy is important to alleviate anxiety [47],

but the present study indicated that participants’ degree

of exposure achievement was lower among students with

higher anxiety scores Therefore, it is conceivable that

students with higher anxiety scores may not have been

able to set feasible targets that matched their anxiety

level (meaning that it was difficult for them to accomplish

the exposure task in their daily lives) In the future, it may

be necessary to improve the programme workbook,

espe-cially in relation to how to set a reasonable goal so that

students can select achievable targets that match their

individual capacities in class Assistance for students with

high anxiety who experience difficulty with gradual

expo-sure will also lead to the provision of early intervention

and support at school, which will be very helpful to such

students

Limitations and future prospects

There were several methodological problems and limi-tations with the present study, as follows First, because this was a pilot study, the number of participants may have been insufficient The study enabled the calculation

of sample size to detect clinically significant differences

in outcome measures Using the PS Power and Sample Size Calculator Software version 3.1.2 with α equivalent

to 05 and power (1−β) of 80, the required sample size for this type of research was found to be 200 participants each for the intervention and control groups [48] Addi-tionally, in this study, the anxiety scale (SCAS) scores dif-fered significantly between the intervention and control groups, possibly due to differences in grade between the students in these groups In the future, we aim to verify the efficacy of the programme by recruiting intervention and control groups with an appropriate number of par-ticipants from the same academic year

Next, according to systematic reviews and meta-anal-yses of school-based anxiety and depression prevention programmes, the effect size of such preventive pro-grammes is small, but it has been indicated that, even with a small effect size, there is a possibility that it can

be useful for preventing the onset of these disorders in youth [19] Additionally, research reports that young people (aged 7–14 years) with anxiety commonly worry about how others perceive them, and thus tend to give socially desirable responses instead of providing valid self-report [49] In the future, in order to evaluate the effects of preventive programmes, it will be necessary not only to evaluate efficacy using questionnaires (i.e., self-report), but also to design a long-term study in which a follow-up study of participants’ changes in anxiety score and the number of school refusals is conducted

Conclusions

Following the delivery by classroom teachers of the univer-sal anxiety prevention programme ‘Journey of the Brave’ for junior high school students in Japan, the feasibility

of the programme implementation in junior high school was partially confirmed However, there was no signifi-cant reduction in anxiety scores such as observed follow-ing implementation of the same programme in elementary schools This pilot study represented the first attempt to have classroom teachers deliver this programme and to use the programme with junior high school students Going forward, in consideration of the results and of the nature

of junior high school classes, we intend to improve the effi-cacy of the programme for this age group by modifying the workbook and number of session as well as by providing more detailed and structured teacher supervision In addi-tion, as there were several limitations to the design of this study, it will be necessary to test the feasibility and efficacy

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