Nghiên cứu chất lượng sống ở người nhiễm HIV và phân tích đa mức độ các yếu tố ảnh hưởng _Quality of Life among HIVAIDS and Multilevel Analysis on influencing Factors in west of China

Nghiên cứu chất lượng sống ở người nhiễm HIV và phân tích đa mức độ các yếu tố ảnh hưởng _Quality of Life among HIVAIDS and Multilevel Analysis on influencing Factors in west of ChinaBACKGROUDHIVAIDS is one of the most devastating illnesses that humans have ever faced. HIV infection and AIDS patients are especially dependent on illegal drug use, and HIVAIDS is very prominent in YUNNAN. Quality of life (QoL) is particularly relevant in research involving patients with acquired immune deficiency syndrome (AIDS).METHODStudy area and populationFrom January 2011 to March 2011, crosssectional surveys were conducted in these three cities, Longchuan in Dehong, Gejiu in Honghe and Kunming.

QUALITY OF LIFE AMONG HIV/ AIDS AND MULTILEVEL

ANALYSIS ON INFLUENCING

FACTORS IN WEST OF CHINA

1 School of public health Kunming Medical University

2 Yunnan Provincial Collaborative Innovation Center for Public Health and Disease Prevention and Control

Wenlong CUI 2015-9-26

Backgroud

 HIV/AIDS is one of the most devastating

illnesses that humans have ever faced

 HIV infection and AIDS patients are especially dependent on illegal drug use, and HIV/AIDS is very prominent in YUNNAN

 Quality of life (QoL) is particularly relevant in research involving patients with acquired

immune deficiency syndrome (AIDS)

 Study area and population

 From January 2011 to March 2011, cross-sectional

surveys were conducted in these three cities, Longchuan

in Dehong, Gejiu in Honghe and Kunming

 Data collection and measurement

 Each participant who gave informed consent was personally interviewed by one of the interviewers using a pre-tested and structured questionnaire

 Trained investigators from the Kunming Medical University conducted face-to-face interviews with patients with the

support of staff at their local Center for Disease Control and Prevention (CDC)

 With an overall response rate of 94.18%, we conducted full interviews with a total of 503 participants: 245 in Kunming city, 158 in Gejiu city, and 113 in Longchuan city

ASSESSMENT OF QOL

 QoL was evaluated using a 35-item, simplified Chinese, simplified version of the Medical

Outcomes Study HIV Health Survey

(MOS-HIV) questionnaire.

 The simplified Chinese version of the

MOS-HIV questionnaire has previously been

demonstrated to have good reliability and

validity.

ASSESSMENT OF QOL

 The MOS-HIV measures 10 domains, including 8 multi-item domains (general health, physical function, role function, cognitive function, pain, mental health,

energy/fatigue, and health distress) and 2 single-item domains (social function and QoL)

 Two summary scores, namely the physical health

summary (PHS) score and mental health summary

(MHS) score, were generated from the factor analysis of the 10 scales

 Table 1 Demographic characteristics of the study population

Characteristics   HIV   AIDS  

    No persons Percentage No persons Percentage

Age group 18-39 242 61.6 63 57.3

Ethnicity (%) Han 272 69.2 84 76.4

Gender female 146 75.6 47 24.4

Table 2 QOL of HIV and AIDS on the study population

general health 44.83±23.95 35.81±23.57 0.001

physical function 81.99±21.15 69.39±27.35 0.000

role function 62.98±46.40 39.54±46.97 0.000

cognitive function 71.95±24.65 63.27±29.39 0.000

mental health 63.51±22.47 58.69±22.13 0.047

energy/fatigue 51.51±24.15 44.59±23.74 0.008

health distress 74.55±21.66 67.64±24.60 0.008

social function 74.20±32.56 60.91±35.41 0.000

 Table 4 95% CI for multilevel logistic regression analysis of PHS and MHS in HIV responders

Predictors PHS Score MHS Score

(Constant) 54.020(46.240, 61.800) 51.703(42.634, 60.771)

Income level 2.834*(.276, 5.392) 1.561(-1.003, 4.125)

Work status -3.331**(-5.463, -1.198) -.878(-2.984, 1.229)

Subjective Support

3.412**(1.278, 5.545) 2.146*(.032, 4.259)

Use of support 1.283(-.772, 3.338) 2.574*(.544, 4.605)

Gender -2.169*(-4.239, -.099) -6.230**(-8.279, -4.181)

route of infection

-6.133**(-9.574,-2.692 ) -5.429**(-8.840, -2.018)

Age group -4.339**(-6.426, -2.252) -2.351*(-4.408,-.295 )

(*p<0.05, **p<0.01)

 Among the annually reported new HIV infections, the ratio

of men to women decreased from 5:1 in 1990s to 2.3:1 in

2009 The proportion of females living with HIV increased from 15.5% to 40.3% in Yunnan

 Results show that the PHS and MHS scores were lower for patients infected from drug use than those infected from sexual contact

CONCLUSION

 Females who acquired the disease from heterosexual

transmission had a better QoL than males and drug users