Nghiệm pháp mới dự báo người bệnh suy tim có tăng ure và creatinine khi dùng lợi tiểu

NEW MECHANISM EXPLAINING FLUID OVERLOAD IN PATIENT WITH DIASTOLIC HEART FAILURE OR HEART FAILURE PATIENT WITH PRESERVED EJECTION FRACTION : WHEN THE VEINS CAUSE HYPERTENSION IN THE AR

NEW MECHANISM EXPLAINING FLUID OVERLOAD

IN PATIENT WITH DIASTOLIC HEART FAILURE OR

HEART FAILURE PATIENT WITH PRESERVED

EJECTION FRACTION : WHEN THE VEINS CAUSE

HYPERTENSION IN THE ARTERY

Presenter : Dinh Tran Xuan Truong

OUTLINE

1.BACKGROUND 2.METHODS

3.RESULT

4.CONCLUSION

BACKGROUND

Heart failure

(HF)

Ejection of blood

Ventricular filling

Structural and functional impairment

HFpEF

BACKGROUND FLUID OVERLOAD

Intravascular (mainly venous) compartment

Extravascular compartment

METHODS

 CHOOSE SAMPLE

 Time : From January 2015 to April 2016

 Number of patient : 25 patients

 Dx : HFpEF

 CLASSIFY THE PATIENTS

 Location of fluid overload depending on SEFV test

 Present with pulmonary HTN or prediction of future pulmonary HTN

 STATISTICAL ANALYSIS:

 Fisher’s exact test for categorical variables

 Two-sample t-test for continuous variables

METHODS

65%

13%

More compliant More elastic

METHODS

Normal Person

1 < 𝑅𝐶

𝑅𝐵 < 2

𝑅𝐵

𝑅𝐶

METHODS

𝑹𝑽 ≫ 𝑹𝑨

𝑹𝑨

𝑹𝑽

𝑹𝑨

𝑹𝑽

𝑹𝑽 < 𝑹𝑨

RESULTS

January 2015  April 2016

25 patients

HFpEF Size and Expansion of the Femoral Vein (SEFV) test

20/25 (80%)

HFpEF

extravascular fluid overload

the size of the femoral vein varied from is small or enlarged without good expansion upon cough

CONCLUSION

The failure of the

venous system HFpEF

Fluid overload mainly in the venous compartment

Larger scale of clinical trial

or registries confirming this new concept are needed

Thank You