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• The patients of the control group received the usual tests as indicated and the patients in the study group received the new Size and Expansion of the Femoral Vein SEFV of which the re

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New Test to Diagnose Vasovagal

Syncope

Advait Soni, Chau Thai Nguyen , Thach

Nguyen

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Background

• Current diagnosis of vasovagal syncope is by exclusion after all the other tests are negative Other tests include CT scan of the head,

carotid arterial Doppler and tilt table test

which are time consuming, non-specific, costly and not cost effective

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• Patients with history of vasovagal syncope

who arrived to the emergency room were

enrolled

• The patients of the control group received the usual tests as indicated and the patients in the study group received the new Size and

Expansion of the Femoral Vein (SEFV) of

which the results were shown to the

investigators

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Principles on the Size and Expansion of the

Femoral Vein (SEFV) test

• The first principle: The volume of blood going

through the femoral artery and returning

through the common femoral vein should be

the same

• If so, in normal condition, the size of the

femoral artery and the femoral vein should be the same

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Principles on the Size and Expansion of the

Femoral Vein (SEFV) test

• The second principle: In the vascular system,

most of the circulating blood is in the veins The amount of blood in the arteries is small and the

size of the arteries does not change much due to vascular tone in order to keep a fairly constant

blood pressure If there is a need to increase

cardiac output, the most common mechanism is

by increasing the heart rate

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• Figure 1 - In this figure, the vein is seen at the bifurcation

as the femoral artery divides into the superficial and deep femoral arteries

New Non-Invasive SEFV Test

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• Figure 2 Here at the distal end of the common femoral artery, the coronal plane of the artery is seen as a single round structure which pulsates Next to it is the femoral vein The size of the

femoral vein is at the same of the common

femoral artery

New Non-Invasive SEFV Test

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New Non-Invasive SEFV Test

Figure 3 Normal expansion of the femoral vein

to less than 2 times larger than the baseline

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Excessive Venous Pooling

Causing Syncope

Figure 4 Panel A The femoral vein at its baseline Panel B The femoral vein expanded to a huge volume upon cough The

is the evidence of excessive pooling causing orthostatic

hypotension

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Venous Compartment Contraction due

to Blood Loss, Dehydration or

Pulmonary Hypertension

• If the vein does not expand with cough, then the patient could have suboptimal venous

capacity (e.g secondary to dehydration or bleeding) The vein is barely filled with

blood and has no extra volume to expand

even with higher pressure from the lungs

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Venous Compartment Contraction due

to Blood Loss, Dehydration or

Pulmonary Hypertension

Figure 5 Abnormal expansion of the femoral vein: The vein does not change size upon cough Either the vein is barely filled with blood (e.g during bleeding) or due to

pulmonary hypertension

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Venous Compartment Contraction due to Blood Loss, Dehydration or Pulmonary

Hypertension

• If the SEFV is abnormal, either without

expansion or excessive expansion, then the cause of syncope would be due to volume contraction or orthostatic hypotension

There is no functional vasovagal syncope here

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RESULTS

• 20 patients were enrolled from June 2015 to

April 2016 All came with history of near

syncope or syncope All patients had negative work-up and some patients were diagnosed of having vasovagal syncope

• The results showed that 13/20 patients had

abnormal SEFV test All the patients with

vague history of near syncope had normal EFV test

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Conclusion

• The patients with vasovagal symptoms

should have the SEFV test early and if

the results of the SEFV are normal in

combination with a strong history of

vasovagal mechanism, the syncope could

be considered benign and the patient

discharged from the hospital Larger scale

of clinical trial or registries of this new

technique are needed

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THANK YOU

15

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