Air rich in O2 enters the lungs from the atmosphere The diaphragm contracts or flattens The intercostal muscles raise the ribs Air rich in C02 exits the lungs The diaphragm
Trang 1The Respiratory
System
Trang 2Learning Outcomes
24.1 Explain the functions of the respiratory
system.
24.2 Explain the difference between internal
respiration and external respiration.
24.3 Describe how the larynx produces voice
sounds
24.4 List the structures contained within the lungs
24.5 Describe the coverings of the lungs and
chest cavity.
Trang 3Learning Outcomes (cont.)
24.6 Describe the events that lead to the
inspiration and expiration of air.
24.7 Explain how the brain controls breathing and
how normal breathing patterns can be disrupted.
24.8 Describe how oxygen is transported from the
lungs to body cells.
Trang 4Learning Outcomes (cont.)
24.9 Describe how carbon dioxide is transported
from body cells to the lungs.
24.10List and explain various respiratory volumes
and tell how they are used to diagnose respiratory problems.
24.11Describe the causes, signs and symptoms,
and treatments of various diseases and disorders of the respiratory system
Trang 6Organs of the Respiratory System
Trang 7Nasal Cavity
• Nasal septum divides the cavity into right and
left portions
– Nares – openings of the nose
• Nasal conchae extend from walls of nasal
cavity
• Mucous membrane warms and moistens the air
• Cilia help eliminate particles
Trang 8Paranasal Sinuses
• Air-filled spaces within
the skull bones
– Open into the nasal
Trang 9Pharynx and Larynx
• Pharynx
– Serves both the respiratory and digestive systems
• Larynx
– Also called the “voice box”
– Moves air in and out of the trachea and produces voice
– Composed of three cartilages:
• Thyroid cartilage
• Epiglottic cartilage
Trang 10Vocal Cords
• Stretched between the
thyroid cartilage and
the cricoid cartilage
• Upper – false cords
• Lower – true vocal
cords
• Glottis – the opening
between the vocal
False Vocal Cords
Posterior Portion of Tongue
Trang 11• Referred to as the windpipe
• Tubular organ made of rings of
cartilage and smooth muscle
• Extends from the larynx to the
bronchi
• Lined with cells possessing
cilia (microscopic hair-like projections)
Cilia move mucus up to the throat, where
it is swallowed Smoking destroys cilia
Trachea
Trang 12Bronchial Tree
• Bronchi
– Primary: First
branches off trachea
Trang 13Bronchial Tree (cont.)
• Alveoli
– Thin sacs of cells
surrounded by capillaries
Trang 14The lungs contain connective tissue, the bronchial
tree, nerves, lymphatic vessels, and blood vessels.
Lungs
• Cone-shaped organs
• Right lung – three lobes
• Left lung – two lobes
lungs
Trang 15Apply Your Knowledge
Which of the following sites would be the most
lethal if obstructed by a foreign body?
a Right bronchus
b Left bronchus
c Trachea
ANSWER:
Trang 16The Mechanisms of Breathing
Breathing, or pulmonary ventilation, consists of inspiration (inhalation) and expiration (exhalation)
Air rich in O2 enters the lungs
from the atmosphere
The diaphragm contracts or
flattens
The intercostal muscles raise
the ribs
Air rich in C02 exits the lungs
The diaphragm relaxes
The intercostal muscles lower the ribs
Trang 17The Mechanisms of Breathing (cont.)
Trang 18The Mechanisms of Breathing (cont.)
• Causes of altered breathing patterns
Trang 19Apply Your Knowledge
Indicated whether each statement refers to (I) inhalation
or (E) exhalation:
The intercostal muscles lower the ribs
The diaphragm contracts or flattens
The intercostal muscles raise the ribs
The diaphragm relaxes
Air rich in O2 enters the lungs from the atmosphere
Air rich in C02 exits the lungs
Trang 20in the Blood
• Most of the oxygen
binds to hemoglobin
– Oxyhemoglobin
– Bright red in color
• Some oxygen remains
dissolved in plasma
• If CO2 combines with hemoglobin at O2
sites, it forms carboxyhemoglobin
Trang 21in the Blood (cont.)
• Carbon dioxide gets into the bloodstream
– Reacts with water in plasma and forms
carbonic acid
– Carbonic acid ionizes and releases hydrogen
and bicarbonate ions
– Bicarbonate ions attach to hemoglobin
• Exhaled as waste product in the lungs
Trang 22Apply Your Knowledge
Describe what happens to carbon dioxide in the
blood.
ANSWER: Carbon dioxide can combine with hemoglobin
and form carboxyhemoglobin Most reacts with water in
plasma to form carbonic acid The carbonic acid ionizes
and releases hydrogen and bicarbonate ions The
bicarbonate ions then attach to hemoglobin and are
exhaled as a waste product from the lungs.
Super!
Trang 23Respiratory Volumes
• Different volumes of
air move in and out of
lungs with different
Trang 24Respiratory Volumes (cont.)
Amount of air that moves in or out of the lungs during a normal breath
Amount of air that can be forcefully inhaled following a normal inhalation
Amount of air that can be forcefully exhaled following a normal exhalation
Trang 25Respiratory Volumes (cont.)
Amount of air that can be forcefully exhaled after the deepest inhalation possible
Volume of air that always remains in the lungs even after a forceful
Trang 26Apply Your Knowledge
_ Amount of air that moves during
a normal breath
_ Amount of air that always
remains in the lungs
_ Total amount of air the lungs
can hold
_ Amount of air forcefully exhaled
after deepest inhalation possible
A Total lung capacity
Trang 27• Due to vibration of soft
tissues when muscles of
the palate, tongue, and
– May be associated with
obstructive sleep apnea
• Common Causes
– Enlargement of tonsils
or adenoids– Being overweight– Alcohol consumption– Nasal congestion
– Deviated nasal septum
Trang 29Snoring (cont.)
• Lifestyle modifications to reduce snoring
– Lose weight– Change sleeping position– Avoid using alcohol or medications that induce sleep– Use nasal strips to widen the nasal passages
– Use dental devices to keep airways open
• Treatments
– CPAP– Surgery (uvulotomy)– Laser surgery
Trang 30Common Diseases and Disorders
Disease Description
Allergic
rhinitis Hypersensitivity reaction to various airborne allergens
Asthma A condition in which the tubes of the
bronchial tree become obstructed due to inflammation
Atelectasis Collapsed lung
Bronchitis Inflammation of the bronchi often follows a
cold; one type of COPD
Trang 31Common Diseases and Disorders (cont.)
Emphysema A chronic condition associated with
smoking that damages the alveoli; one type of COPD
Influenza A viral disease that attacks the
respiratory system; commonly called
Trang 32Common Diseases and Disorders (cont.)
Disease Description
Laryngitis An acute inflammation of the larynx
causing hoarseness (dysphonia)Legionnaire’s
disease Acute bacterial pneumonia caused by Legionnaire bacteria that usually grows
in the standing water of air conditioning systems
Lung cancer Cancer closely associated with smoking
and exposure to second-hand smoke;
four types of lung cancers
Pleural effusion A buildup of fluid in the pleural cavity
Trang 33Common Diseases and Disorders (cont.)
Disease Description
Pleuritis/Pleurisy Inflammation of the membranes that
cover the lungs, known as pleura
Pneumoconiosis Lung diseases that result from years
environmental or occupational exposure to different types of dust;
three types
Pneumonia/
Pneumonitis An inflammation of the lungs that is most often caused by a bacterial, viral,
or fungal infection
Trang 34Common Diseases and Disorders (cont.)
Disease Description
Pneumothorax A collection of air in the chest around the
lungs, which may cause atelectasis
Pulmonary
edema A condition in which fluids fill spaces within the lungs, making it very difficult for
the lungs to oxygenate the blood Pulmonary
embolism A blood clot (embolism) that travels usually from the legs and blocks an artery
in the lungs
Trang 35Common Diseases and Disorders (cont.)
Disease Description
Respiratory
distress
syndrome (RDS)
Syndrome in which a lack of surfactant
in the lungs allows the alveoli to collapse on exhalation, resulting in poor oxygenation
Sinusitis An inflammation of the membranes
lining the sinuses of the skull
Trang 36Common Diseases and Disorders (cont.)
Disease Description
Sudden infant
death syndrome
(SIDS)
A syndrome without characteristic signs
or symptoms; usually a baby with this disorder simply goes to sleep and
never wakes up
Tuberculosis Primarily a respiratory disease caused
by various strains of the bacterium
Trang 37The medical assistant working for a general practitioner is
taking the medical history of a new patient The patient
states, “Even after sleeping 8 to 9 hours, I still feel really
tired.” The patient’s spouse states, “Well, you sure snore
loud, as if the sleep is so good.” Which of the following is a
possible cause for the excessive fatigue?
Trang 38In Summary
24.1 The function of the respiratory system is to move air
in and out of the lungs in a process known as ventilation, respiration, or breathing
24.2 The exchange of oxygen and carbon dioxide in the
lungs is called external respiration The same exchange within the hemoglobin of red blood cells is internal respiration
24.3 The larynx contains the vocal cords, which stretch
between the thyroid and cricoid cartilages The muscles of the lower (true) vocal cords stretch and relax them to produce different sounds
Trang 39In Summary (cont.)
24.4 The lungs contain connective tissue, the bronchial
tree, nerves, lymphatic vessels, and blood vessels
The left lung consists of two lobes (upper and lower), and the right lung consists of three lobes (upper,
middle, and lower)
Within each lung are the primary, secondary, and tertiary branches of the bronchi, the bronchioles, and the alveoli
24.5 The lungs are covered by, and the chest cavity is
lined with, the pleura The outer membrane is the parietal pleura and the inner membrane is the visceral
Trang 40In Summary (cont.)
24.6 During inspiration, the diaphragm contracts and the
intercostal muscles raise the ribs, increasing the space in the thoracic cavity
This decreases the pressure within the cavity so that the air outside the body passively flows into the
thoracic cavity
During expiration, the diaphragm relaxes, pushing up into the thoracic cavity, and the intercostal muscles lower the ribs, forcing the air to flow out of the body
Trang 41In Summary (cont.)
24.7 Breathing is controlled by the respiratory center of the
brain located in the pons and medulla oblongata
Carbon dioxide levels and pH levels of the blood also affect breathing Everyday situations such as
coughing, sneezing, laughing, crying, hiccups, yawning, and speaking also alter breathing patterns
24.8 Most of the oxygen in the bloodstream binds to the
hemoglobin within red blood cells, resulting in oxyhemoglobin, although a small amount does not bind to hemoglobin and remains dissolved in the plasma
Trang 42As carbonic acid ionizes, it releases hydrogen and bicarbonate ions, which attach to hemoglobin making its way back to the lungs to be exhaled.
Trang 43In Summary (cont.)
24.10Respiratory volumes are measured to check the
health of the respiratory system
The volumes are listed here and the normal capacities are found in the chapter: tidal volume, inspiratory and expiratory reserve volumes, residual volume, inspiratory capacity, functional residual
capacity, vital capacity, and total lung capacity
Trang 44In Summary (cont.)
24.11The diseases and disorders of the respiratory system
are many and varied, as are the causes and treatments of these diseases Many of the more common respiratory disorders, with their individual causes and treatments, are discussed in detail in the Pathophysiology section of this chapter
Trang 45End of Chapter 24
The air of ideas
is the only air
worth
~Edith Wharton