40 2008 129–143 Genetic and metabolic aspects of androstenone and skatole deposition in pig adipose tissue: A review Annie ROBIC 1*, Catherine LARZUL2, Michel BONNEAU3 1 INRA, UMR 444 de
Trang 1Genet Sel Evol 40 (2008) 129–143
Genetic and metabolic aspects
of androstenone and skatole deposition
in pig adipose tissue: A review
Annie ROBIC 1*, Catherine LARZUL2, Michel BONNEAU3
1 INRA, UMR 444 de Ge´ne´tique cellulaire, BP52627, 31326 Castanet-Tolosan, France
2
INRA, UR337 Station de ge´ne´tique quantitative et applique´e, 78352 Jouy-en-Josas, France
3
INRA, UMR1079 Syste`mes d’e´levage, nutrition animale et humaine, INRA-Agrocampus
Rennes, Domaine de la Prise, 35590 Saint-Gilles, France
It has been drawn to the attention of the authors that in Figure1the common intermediate products of the transformation of progesterone and 5,16 dien-3bol into androstenone is 4,16-androstadien-3-ene (and not 4,16 androsta-dien-3-one) In addition, the list of the final products of androstenone sulfonation has been completed
This corrigendum published in issue 5, 2008 is freely available in electronic form on the web site of GSE (http://www.gse-journal.org/)
*
Corresponding author: annie.robic@toulouse.inra.fr
Genet Sel Evol 40 (2008) 581–582
Ó INRA, EDP Sciences, 2008
DOI: 10.1051/gse:2008023
Available online at: www.gse-journal.org
Article published by EDP Sciences
Trang 2HO HO
HO
andien- β synthetase (CYB5, CYP17…)
O
CYP21
5,16-androstadien-3 β-ol
4,16-androstadien-3-one
O
androstenone
3 βHSD
3 αHSD
HO
hydroxysteroid sulfotransferase
O
SRD5A
5 α-androsten-3β-ol (β-androstenol)
5 α-androsten-3α-ol (α-androstenol)
3 βHSD
hydroxy-androstenone andro 3-enol
hydroxysteroid sulfotransferase
andro 3-enol sulfate
hydroxysteroid sulfotransferase
hydroxy-androstenone sulfate
3 α-androstenol sulfate
androstadienol sulfate
3 β-androstenol sulfate
11-deoxycorticosterone
4,16-androstadien-3-ene
Figure 1 Main enzymes involved in the porcine metabolism of androstenone.