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Hip disorders are common in chil-dren with cerebral palsy and cover a wide spectrum—from the hip at risk to subluxation, dislocation, and dislocation with severe degenera-tion and pain..

Trang 1

Hip disorders are common in

chil-dren with cerebral palsy and cover a

wide spectrum—from the hip at

risk to subluxation, dislocation, and

dislocation with severe

degenera-tion and pain Three principles

guide the management of these

dis-orders First, the pathophysiology

of spastic hip dysplasia differs from

that of developmental dysplasia of

the hip (Table 1) In children with

cerebral palsy, the hips are usually

normal at birth; with growth,

how-ever, a combination of muscle

im-balance and bony deformity leads to

progressive dysplasia Second, the

natural history of hip dysplasia is

marked by increasing dysfunction

With progression of hip subluxation

or dislocation, there is an

increas-ingly adverse effect on hygiene,

sit-ting, and gait, as well as pain by

early adulthood for many of those affected.1,2 Third, salvage options for the skeletally mature patient with a neglected hip are limited

The care of hip disorders in patients with cerebral palsy has incorporated early detection and comprehensive treatment This has resulted in greatly improved outcomes, al-though certain aspects of the patho-physiology and management remain controversial

Epidemiology and Natural History

The reported incidence of hip dys-plasia in patients with cerebral palsy varies widely, ranging from 2% to 75%.3 The children with the most severe neurologic involvement tend

to have the worst hips,4and patients who never achieve the ability to sit independently have the highest risk.5 Lonstein and Beck6 found hip subluxation or dislocation in 7% of independent ambulators but

in 60% of dependent sitters Chil-dren who can pull themselves to a standing position by age 3 years have a better prognosis, with a lower incidence of hip problems.5 The natural history of spastic hip dysplasia varies, but many of the children who progress to disloca-tion develop a chronically painful hip by early adulthood.1-3 This pro-gression of dysplasia is gradual, generally occurring over a period of several years Once a hip begins to subluxate, it rarely improves with-out treatment Exceptions include a hip that becomes the abducted side

in a windblown deformity or a hip

on the low side of the pelvic obliquity caused by scoliosis Hips with a

Dr Flynn is Assistant Professor of Ortho-paedics, Division of Orthopaedic Surgery, The Children’s Hospital of Philadelphia, Phila-delphia, PA Dr Miller is Associate Professor

of Orthopaedics, Department of Orthopaedic Surgery, Alfred I duPont Institute, Wilmington, DE.

Reprint requests: Dr Flynn, The Children’s Hospital of Philadelphia, 34th and Civic Center Boulevard, Philadelphia, PA 19104-4399 Copyright 2002 by the American Academy of Orthopaedic Surgeons.

Abstract

Hip disorders are common in patients with cerebral palsy and cover a wide

clin-ical spectrum, from the hip at risk to subluxation, dislocation, and dislocation

with degeneration and pain Although the hip is normal at birth, a combination

of muscle imbalance and bony deformity leads to progressive dysplasia The

spasticity or contracture usually involves the adductor and iliopsoas muscles;

thus, the majority of hips subluxate in a posterosuperior direction Many

patients with untreated dislocations develop pain by early adulthood Because

physical examination alone is unreliable, an anteroposterior radiograph of the

pelvis is required for diagnosis Soft-tissue lengthening is recommended for

children as soon as discernable hip subluxation (hip abduction <30°, migration

index >25%) is recognized One-stage comprehensive hip reconstruction is

effective treatment for children 4 years of age or older who have a migration

index >60% but who have not yet developed advanced degenerative changes of

the femoral head Salvage options for the skeletally mature patient with a

neglected hip are limited.

J Am Acad Orthop Surg 2002;10:198-209 Patients With Cerebral Palsy

John M Flynn, MD, and Freeman Miller, MD

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migration index (MI) >50% do not

reduce spontaneously;

approxi-mately one third will progress to

dislocation.3 The greatest risk of

dislocation occurs during middle

childhood ages (4 to 12 years) Later

dislocation may be due to

unrecog-nized hydrocephalus or shunt

dys-function.7 As the hip progresses

from subluxation to dislocation, the

articular cartilage of the femoral

head is subjected to enormous

pres-sure from the surrounding soft

tis-sues and rapidly degenerates

Dislocated hips are more painful

than hips that remain subluxated or

reduced; subluxated hips are only

slightly more painful than reduced

hips.3

Anatomy and Pathophysiology

In children with spastic hip dyspla-sia, the hip joint is normal at birth.8 With growth, excessive muscle tone exerts a constant force on the devel-oping hip, leading to deformation of both the proximal femur and acetab-ulum Because the spasticity or con-tracture usually involves the adduc-tor and iliopsoas muscles, most hips subluxate in a posterosuperior direc-tion The hip’s center of rotation gradually shifts from the center of the femoral head to the lesser trochanter

Femur

The abnormalities of the

proxi-mal femur, including dysplastic and degenerative changes, persistence of fetal anteversion, and coxa valga, have been characterized both radio-graphically and pathologically The spastic hip adductors and flexors drive the femoral head into the pos-terolateral acetabular labrum The capsule and superior rim of the ace-tabulum cause focal deformation of the femoral head This indentation locks the femoral head at the lateral acetabular margin, leading to pain from cartilage erosion (Fig 1) The epiphysis becomes wedge-shaped and displaces superolaterally In one study of three-dimensional computed tomography (CT) scans, all nonambulatory patients had deformities of the femoral head that ranged from mild medial flattening

to wedge-shaped defects.9 In most hips, the lesser trochanter is en-larged while the greater trochanter maintains its normal proportions Most evidence suggests that in spastic hip dysplasia, femoral ante-version is increased The neck-shaft angle also may be somewhat higher

in certain children, although most of the coxa valga seen on radiographs

is caused by the anteversion Chil-dren with spastic hip dysplasia have normal anteversion at birth, but the normal decrease in antever-sion does not occur during early childhood

Acetabulum

Great progress has been made in understanding the acetabular ab-normalities in spastic hip dysplasia Computerized mathematical mod-els demonstrate that a child with spastic hip disease has a sixfold increase in hip-force magnitude.10 This constant abnormal force causes changes quite early The acetabular index (AI) in affected children is normal until 30 months of age, then becomes notably higher.11 Studying arthrograms, Heinrich et al12found that the bony maturation of the acetabulum is retarded by

deforma-Table 1

Comparison of Spastic Hip Dysplasia and Developmental

Dysplasia of the Hip

Developmental Dysplasia

Findings at birth Hip usually normal Hip usually abnormal

Age at risk Usually normal in the first Most often recognized in

year of life; recognized the first year of life after age 2 yr

Detection Radiographs needed in Physical examination in

Etiology Spastic muscles drive femoral Mechanical factors

head out of an otherwise (eg, breech), ligamen-normal acetabulum, pelvic tous laxity, abnormal

Childhood Progressive subluxation Progressive subluxation

Natural history Pain in many subluxated or Pain in many subluxated

dislocated hips by second hips by fourth or

Acetabular Usually posterosuperior Usually anterior

deficiency

Early measures Muscle lengthening Pavlik harness or closed

reduction Missed or failed Hip osteotomies, often Closed or open reduction,

early measures without open reduction often without

osteoto-mies (before age 18 mo) Salvage Castle procedure osteotomy, Usually total hip

interposition arthroplasty replacement

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tion of the lateral pelvic

cartilagi-nous anlage that occurs before or

during the subluxation The

great-est increase in the deformation of

the acetabulum occurred in hips

with an MI of 52% to 68%

In most cases, the acetabular

defi-ciency is posterosuperior.13

Insta-bility is usually unidirectional,

fol-lowing a trough created by pressure

of the femoral head (Fig 2) In the

rare cases of extension posturing,

the dislocation and associated

ace-tabular deficiency is anterior After

analyzing three-dimensional CT

scans, Kim and Wenger14confirmed

that the major acetabular deficiency

normally coincided with the

direc-tion of the subluxadirec-tion or

disloca-tion but stressed that excepdisloca-tions

occur There is no agreement as to

whether the acetabulum is actually

shallow9or normal in depth.13

Special Cases

Windblown Hip

Windblown hip describes an

adduction deformity of one hip and

an abduction deformity of the other,

resulting in pelvic obliquity and

pelvic rotation Windblown hips

are caused by asymmetric activity

of the adductors, abductors, and internal and external rotator mus-cles, usually affecting totally in-volved nonambulatory children with severe spasticity Electromyo-graphic studies have shown that the adductors are overactive on both sides, while the abductor is overac-tive only on the abducted side.15 The relationship of scoliosis to wind-blown hips remains controversial

Black and Griffin16studied 80 pa-tients and concluded that in-frapelvic obliquity (caused by the asymmetric muscle forces around the hip) is more important than suprapelvic obliquity caused by sco-liosis Infrapelvic obliquity occurs first, and the hip on the infrapelvic high side is almost always the one that dislocates

Anterior Dislocation

Subluxation or dislocation occurs anteriorly in only 1.5% of cases

Most of these occur in severe quad-riplegia with extension posturing or hypotonia Three clinical scenarios have been identified: (1) patients with hip extension, external rota-tion, and adduction with knee

ex-tension contractures; (2) patients with hip extension, external rota-tion, and abduction with knee flex-ion contractures; and (3) patients with severe hypotonia with no con-tractures.17 Seating children with anterior dislocations and contrac-tures is very difficult Because of an associated thoracolumbar kyphosis,

a semirecumbent position is re-quired About 50% of children with anterior dislocations have pain.17

Physical Examination

During the physical examination of the hips, abduction should be tested with the hip and knee extended The child with a windblown hip may have a “pseudo-Galeazzi” sign due to the one-sided adduction con-tracture that creates the appearance

of a leg-length discrepancy.15 Knees and ankles also should be tested for range of motion, and the spine examined for evidence of scoliosis

If the child is nonambulatory, the spine and pelvis should be evalu-ated in the sitting position to assess pelvic obliquity and its effect on seating Physical examination alone

is unreliable to diagnose most pos-terosuperior spastic hip subluxa-tions or dislocasubluxa-tions In patients with anterior dislocations, the

Figure 1 A, Anteroposterior pelvic radiograph of a 17-year-old boy with quadriplegic

cerebral palsy Constant severe pain in the left, adducted hip worsened after his pelvic

obliquity was corrected with spinal fusion A Castle femoral resection was done to allow

him to sit comfortably B, The resected femoral head has a triangular shape and evidence

of advanced degenerative changes, including complete loss of articular cartilage on the

medial, lateral, and superior surfaces.

Figure 2 A three-dimensional

reconstruc-tion of a preoperative CT scan showing typical posterosuperior dislocation The acetabulum is severely dysplastic in the area of dislocation but normal anteriorly.

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oral head may be palpable as a

prom-inent, hard mass in the groin

Radiologic Evaluation

The supine anteroposterior

radio-graph of the pelvis is used to screen

and follow children at risk for spastic

hip dysplasia Both the MI and AI

should be measured (Fig 3)

Be-cause the MI depends on the

posi-tion of the legs, imaging should be

done in neutral adduction/abduction

The upper limit of normal for the MI

is 25% at age 4 years;18however, the

measurement error of the MI is

±10% Rotation of the pelvis will

decrease the AI on the lower side.11

Forward pelvic tilt (eg, with a fixed

flexion deformity of the hip) will

de-crease the AI and can make the

femoral/acetabular relationship

dif-ficult to interpret (Fig 4) To get an

accurate assessment of the

acetabu-lum, the technician should

maximal-ly flex the contralateral hip and knee

to eliminate the lumbar lordosis

A direct relationship exists be-tween the MI and AI The AI stead-ily increases as the MI increases, measuring about 40° when the MI is 50%.8 The shape of the sourcil has been classified as of two types.19 In type 1, the lateral corner is sharp and below the weight-bearing dome

of the acetabulum (Fig 3) In type 2, the lateral corner is blunted, turned upward, and above the weight-bearing dome

In some cases, additional preop-erative imaging studies may add valuable information CT with three-dimensional reconstruction allows the surgeon to assess defor-mities of the femoral head and the location of the area of greatest acetabular deficiency (posterosupe-rior in most, but not all, patients)

Adding a cut through the distal femur allows calculation of femoral anteversion CT with three-dimen-sional reconstruction is also useful for accurate analysis of anterior hip dislocation; the MI may be normal because these hips do not dislocate laterally.17 Real-time ultrasound is

a quick, accurate, and less expen-sive alternative to measure femoral anteversion without radiation

Ultrasound is particularly good in cases of coxa valga, where CT may

be inaccurate

Preoperative arthrography does not help with decision-making in spastic hip dysplasia In the child with spastic hip disease, the hip is typically normal for the first few years and the femoral head at the time of surgery is much more ossi-fied than it is in a child with devel-opmental dysplasia Adequacy of reduction is easily evaluated without

an arthrogram By comparison, the child with developmental dysplasia

of the hip is usually less than 2 years old with a minimally ossified femoral head that has been abnormal since in-fancy Arthrography in developmen-tal dysplasia of the hip will outline the cartilage and show interposed tis-sue that is blocking reduction

Nonsurgical Management

Several nonsurgical measures have been used to prevent or slow the progression of spastic hip dysplasia Physical therapy has traditionally been used to help preschool-age children with cerebral palsy reach their maximum potential A therapy program should include activities designed to maintain hip motion and promote weight bearing How-ever, there is no convincing evi-dence that therapy alone prevents hip subluxation Abduction bracing does not prevent hip dislocation20 and, if used aggressively, actually may cause windblown hips or hyperabduction deformity.21 Botu-linum toxin A can be injected into the adductors to temporarily de-crease tone for 4 to 6 months, but no long-term studies have compared its efficacy to that of no treatment or therapy alone The iliopsoas, a major factor in spastic hip disease, is difficult to inject reliably

The most important facet of non-surgical management is careful monitoring During the preschool years, hip abduction, with the hips and knees extended, should be

test-ed and recordtest-ed The MI and AI

Figure 3 Subluxated hip (right side of

illustration) The migration index (MI) is

calculated by dividing the width of the

uncovered femoral head (A) by the total

width of the femoral head (B) The

acetab-ulum is dysplastic (type 2 sourcil), with the

lateral corner of the acetabulum above the

weight-bearing dome Normal hip (left

side of illustration) with the acetabular

index (AI) indicated There is a normal

(type 1) sourcil; the lateral corner is sharp

and below the weight-bearing dome H =

horizontal axis.

Type 1

A B Type 2

Figure 4 Anteroposterior pelvic radio-graph of a child with bilateral spastic hip dislocation shows the difficulty of measur-ing the AI and MI, or interpretmeasur-ing the rela-tionship between the femur and the acetab-ulum, with a severe hip flexion contracture that tilts the pelvis.

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should be measured on the

antero-posterior pelvic radiograph

Cere-bral palsy patients aged 2 through

8 years should have an orthopaedic

examination twice a year If

abduc-tion of either hip drops below 45°

or the MI is >25%, the hips are at

risk and an anteroposterior pelvic

radiograph should be obtained at

each examination The physician

should not be lulled into a false

sense of security by a normal

radio-graph of an infant; this may

repre-sent a hypotonic phase before the

pathologic forces have begun to do

their damage.5 Hip subluxation

typically begins between the ages

of 2 and 6 years

Caretakers of infants or toddlers

with cerebral palsy often press the

orthopaedic surgeon to estimate the

probability that surgical treatment

of the hips will be needed Because

so many factors contribute to the

risk of spastic hip dysplasia, there is

sparse evidence to support precise

predictions Cooke et al22

retrospec-tively measured the radiographs of

462 patients with cerebral palsy,

studying the predictive effects of the

AI, MI, and neck-shaft angle They

found that a high AI was the most

powerful predictor of hip

disloca-tion All patients with dislocation

had an AI >30° at age 4 years; the

AI was <30° in all patients without

dislocation However, these data should be interpreted with caution

Acetabular dysplasia and pelvic tilt and rotation complicate the accurate measurement of AI Prospective studies are needed to establish reli-able guidelines

Surgical Management Indications for Surgery

Spastic muscles should be length-ened early to prevent the devel-opment of deformity Early com-prehensive reconstruction may be considered if the hip cannot be man-aged with muscle lengthening The natural history of spastic hips sug-gests that untreated dislocations may become painful Reconstruc-tion or salvage opReconstruc-tions for a painful degenerated hip are limited and generally disappointing

Soft-Tissue Lengthening

Soft-tissue lengthening should be done as soon as progressive hip subluxation is recognized Damage

to the acetabulum by the pathologic forces through the femoral head may be greatest before age 4 years.5 Soft-tissue lengthening is indicated

in a child less than 8 years of age who is found to have hip abduction

of <30° and an MI of 25% to 60%

(Fig 5) Lengthening is contraindi-cated in a child with no contractures

or spasticity or in a child 4 years of age or older with subluxation so advanced that bony reconstruction is indicated (MI >60% to 100%) How-ever, lengthening may be appropri-ate in some cases of severe subluxa-tion if the child is very young (<4 years of age) or has multiple medical problems Although one study showed that the failure rate in this age group was 44%, more than half were successfully treated; in the remainder, major bony surgery could be postponed until the bone stock was more substantial and the risk of recurrence lower.23

Soft-tissue lengthening around the hip is done through a transverse skin incision made 1 to 3 cm distal

to the inguinal crease The fascia over the adductor longus tendon is opened longitudinally and the ten-don is transected, taking care to avoid injury to the anterior branch

of the obturator nerve below A myotomy of the gracilis is done next If hip abduction has not improved to 45°, the anterior branch

of the obturator nerve is retracted and the adductor brevis muscle is lengthened until 45° of abduction is obtained Using the interval be-tween the adductor brevis and the pectineus, the iliopsoas tendon is

Figure 5 A, Anteroposterior pelvic radiograph of a 2+6 year-old child with spastic quadriplegia who presented with advanced

subluxa-tion bilaterally Too young for reconstrucsubluxa-tion, the child underwent bilateral soft-tissue lengthening B, Six years after surgery, the hips

are located and the child needed no further hip surgery.

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isolated In nonambulatory patients,

the tendon is divided near the lesser

trochanter In ambulatory patients,

the iliopsoas tendon is retracted as

far proximally as possible and only

the psoas tendon is divided, leaving

the iliacus fibers intact A proximal

hamstring lengthening can be

added in nonambulatory patients if

the knee cannot be extended

beyond 45° (popliteal angle >45°)

Neurectomy of the anterior

branch of the obturator nerve

should not be done in ambulatory

patients The risk of obturator

neu-rectomy is an abduction

contrac-ture—a marked disability for both

walkers and sitters However, it is

unclear whether the abduction

con-tractures noted in the past were due

to the neurectomy or to the spica

casting and abduction bracing

com-monly used after muscle

lengthen-ing Obturator neurectomy may be

appropriate in severely involved,

nonambulatory children, but

guide-lines are not yet well established

Patients are maintained on

diaz-epam (0.1 to 0.2 mg/kg per dose)

every 6 hours to treat the substantial

muscle spasms of the early

postop-erative period Morphine or

co-deine can be given for pain control

Although many surgeons still use

spica or abduction casting after

muscle lengthening, our

postopera-tive protocol is designed to allow

immediate therapy Knee

immobi-lizers and an abduction pillow can

be used for 1 month On the second

day after surgery, therapy for hip

and knee range of motion is begun

Prone lying is encouraged to

pro-mote hip extension Radiographs

are obtained every 6 months

Be-cause most of the improvement

after soft-tissue lengthening occurs

within 6 months, the radiograph

taken 6 months after surgery is an

excellent indication of eventual

suc-cess or failure.23

The success of soft-tissue

length-ening is closely related to the degree

of subluxation at the time of the

surgery Cornell et al24found that if the MI was <40%, soft-tissue length-ening had an 83% success rate

With an MI ≥ 40%, soft-tissue sur-gery alone was successful in only 23% of children All of the hips with

an MI >60% failed An AI >27° was also highly predictive of failure

Age at the time of surgery did not have a significant predictive effect

In a study of 147 hips treated with a protocol of soft-tissue lengthening and immediate mobilization with

no abduction bracing, Miller et al23 found that 88% had a good or fair result (MI <40%) at final follow-up

Hip Reconstruction

Indications and Planning

Patient age and severity of sub-luxation are the two most important factors to consider in hip recon-struction Ideally, hip reconstruc-tion should be done in patients 4 years of age or older but before per-manent, advanced degenerative changes occur Analyzing the 11- to 18-year follow-up of their hip recon-structions, Brunner and Baumann25 found that children less than 4 years

of age had a 96% loss of correction

of the neck-shaft angle They rec-ommended that surgery be post-poned until the child is 8 to 10 years old, if possible Furthermore, from

a practical standpoint, older chil-dren have better bone stock for plate fixation The upper age limit depends on the degree of degenera-tive changes that develop Once the femoral head begins to flatten medi-ally and latermedi-ally, loss of articular cartilage is probable and pain relief after reconstruction is unlikely

Another factor to consider is severity of subluxation The capital femoral epiphysis begins to lose the support of the bony pelvis at an MI

of approximately 50%.12 There is a low probability that soft-tissue lengthening alone can successfully reverse the severely compromised anatomy and mechanics of a hip

with such advanced subluxation Thus, hip reconstruction is indicated for children 4 years of age or older who have severe subluxation (MI

>60%) or dislocation but who have not yet developed advanced degener-ative changes of the femoral head that are unlikely to remodel Hip recon-struction is recommended for chil-dren less than 8 years old who have failed soft-tissue lengthening (MI

>40% 1 year postoperative) and for children more than 8 years old with

an MI >40% but no signs of advanced degenerative change on radiographs Evidence is increasing that the most effective treatment for the severely subluxated or dislocated hip is a one-stage comprehensive approach that includes soft-tissue lengthening; a shortening varus derotation osteotomy of the femur (VDRO); a capsulotomy when nec-essary; and a peri-ilial acetabu-loplasty.1,19,25,26 The soft-tissue lengthening is done initially to achieve at least 45° of hip abduction; otherwise, the varus osteotomy would result in adduction Shorten-ing may be the most important com-ponent of the VDRO Computer-ized mathematical models show that to normalize the mechanical forces of the spastic hip, one must lengthen the psoas, iliacus, gracilis, and adductor longus and brevis muscles, which can reduce the force

on the joint to near normal The benefit of VDRO comes not from the redirection of force but from the bone shortening that acts like a muscle release or lengthening De-creasing femoral anteversion, neck-shaft angle, or both have little effect

on the forces.10 The indications for a capsulotomy are not well estab-lished McNerney et al26 recom-mended an open reduction and cap-sulorrhaphy on every hip with an

MI >70%; they found that only 3%

of such hips resubluxated after open reduction and capsulorrhaphy, while 60% resubluxated when the procedure was not done Miller et

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al19recommended medial

capsulot-omy when abduction is <20° and

the whole femoral head does not

reduce under the acetabulum after

the pelvic osteotomy

The acetabulum has a very limited

ability to remodel once advanced

dysplasia has developed.11

Al-though the surgeon can choose from

several different pelvic osteotomies

to address such dysplasia,

varia-tions of the Dega acetabuloplasty

have proved to be best.1,19,26 The

acetabuloplasty should be done in

all dislocated hips In subluxated

hips, the surgeon should consider

both the AI and the shape of the

sourcil When the AI is ≥ 25°26or

when there is a type 2 sourcil,19an

acetabuloplasty should be done

(Fig 6) Acetabuloplasty is relatively

contraindicated if the triradiate

car-tilage is closed or if advanced

de-generative changes have developed

in the femoral head

Technique

When hip abduction is <45°, a

soft-tissue lengthening is done first

The femoral osteotomy is designed

to achieve a neck-shaft angle of

approximately 100° in

nonambulato-ry and 120° in ambulatononambulato-ry patients.19

Because the protocol includes

imme-diate mobilization and therapy, the

femur must be rigidly fixed (eg, a 90°

blade plate) In nonambulators or

household ambulators, the level of

the osteotomy is planned so that the

entire lesser trochanter is removed,

effecting a release of the iliopsoas In

community ambulators, the lesser

trochanter is kept with the proximal

fragment and the iliopsoas is

pre-served by a more proximal

lengthen-ing With the chisel for the blade

plate in place, the proximal femur is

abducted If the femoral head does

not reduce into the acetabulum, a

medial and anterior capsulotomy is

done and any other blocks to

reduc-tion are addressed

The acetabular osteotomy is done

through an anterior approach in the

interval between the sartorius and tensor fascia lata The edge of the hip capsule is cleared, beginning anteriorly near the anteroinferior iliac spine and working all the way posterior to the triradiate cartilage, taking care to avoid exposing or entering the sciatic notch Under fluoroscopic guidance, a straight osteotome is used to create a peri-capsular cut in the ilium 5 mm above the joint This osteotomy extends from the anterior-inferior iliac spine to the triradiate cartilage but does not extend into the sciatic notch The osteotome, placed as posteriorly as possible in the oste-otomy, is used to lever open the os-teotomy (Fig 7, A) In most cases, the maximum acetabular deficiency

is posterosuperior, so the triangular piece of iliac crest allograft is tapped into the osteotomy as posteriorly as possible, thus making the maximum coverage in the area of greatest dys-plasia (Fig 7, B)

With the acetabular osteotomy complete, the femur can be fixed To judge the amount of femoral short-ening needed, the popliteal angle is

a good gauge With the hip flexed 90° and the knee fully extended

(popliteal angle = 0°), the amount of femoral overlap is marked Usually between 1 and 3 cm is removed, and the femoral shaft is fixed to the blade plate The shortening decreases the remaining force on the joint caused

by contracted muscles, including the hamstrings In ambulatory patients,

a distal hamstring lengthening can

be done prior to the femoral

osteoto-my to reduce the amount of femoral shortening needed If both hips are being reconstructed, leg lengths can

be equalized when the second side is shortened Anteversion should be corrected to between 0° and 15° Overzealous derotation will leave the hip retroverted, increasing the risk of posterior dislocation

The postoperative regimen in-cludes the use of diazepam and narcotics, similar to the muscle-lengthening procedure With stable fixation, no cast or orthotic is needed When a cast is used (eg, if fixation seems inadequate or regular post-operative therapy is not available), the surgeon should be vigilant for skin problems, pulmonary compli-cations (eg, pneumonia), and insuf-ficiency fractures after cast removal Sitting and therapy for range of

Figure 6 A, Anteroposterior pelvic radiograph of advanced hip subluxation (65%) in a

7-year-old child The acetabulum is dysplastic with a type 2 sourcil B, The same patient

after one-stage reconstruction with adductor lengthening, a shortening VDRO with blade plate fixation, and acetabuloplasty.

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motion can begin on the second

postoperative day, and standing can

begin as early as 1 week as comfort

permits Several months of therapy

for range of motion and gait training

is recommended Symptomatic plates

can be removed once the osteotomy

heals

The one-stage comprehensive

approach (Fig 8) has yielded

excel-lent results Using the

comprehen-sive technique, 95% of hips were

stable more than 2 years after

sur-gery, 82% were pain free, 14% had

partial relief, and 4% had persistent

pain.19 Others1,26,27have reported

similar excellent results Persistent

pain is more likely when

preopera-tive radiographs show lateral

fem-oral head flattening.19

Special Cases

Windblown Hip

The windblown hip remains a

difficult clinical problem Unilateral

adductor lengthening is

recom-mended for windblown hips to

avoid unilateral abduction and a

pelvis that is impossible to

con-trol;5,15however, the failure rate is high Abel et al28reported failure in one third of patients, noting that hyperabduction may occur after an ipsilateral adductor release unmasks the abduction tone Bilateral recon-struction with varus shortening osteotomies (VDRO) gives symme-try of appearance and motion Al-though recurrence can be seen with growth, bilateral reconstruction is much more likely to give lasting improvement than soft-tissue proce-dures.28

Anterior Dislocation

For an anterior hip dislocation, the indications for reconstruction are pain and difficulty with sitting

The knee flexion or extension con-tractures should be addressed with muscle lengthening The hip recon-struction includes a varus shorten-ing femoral osteotomy (VDRO) and

a Pemberton-type osteotomy to cre-ate good anterior coverage.17 Selva

et al17reported a good outcome in

11 of 13 patients The authors felt that results in posterior dislocations were better because anterior

dislo-cations are so rare and the affected children have severe neurologic in-volvement

Hip Subluxation After Selective Dorsal Rhizotomy

Children may develop progres-sive hip subluxation after selective dorsal rhizotomy Generally, there

is no adduction contracture Non-ambulatory children with preexist-ing dysplasia are most at risk and should be followed after rhizotomy with a radiograph of the hip each year for several years When pro-gressive subluxation is noted, a hip reconstruction should be done; however, lengthening of the adduc-tors usually is not needed

Salvage Procedures

If muscle lengthening does not succeed in treating subluxation, one-stage comprehensive hip recon-struction has achieved a reported success rate >90% Thus, with an-nual monitoring and appropriately timed surgery, few hips should need a salvage procedure How-ever, many adolescents with cere-bral palsy still present with a pain-ful dislocated hip and advanced degenerative changes They are often unable to sit comfortably and may have skin breakdown and poor perineal hygiene The basic types of femoral salvage options are re-section, redirection, interposition-replacement, and arthrodesis Some surgeons have successfully used a Chiari osteotomy or shelf arthro-plasty for late treatment of hips not amenable to a peri-ileal osteotomy Among the various types of fem-oral resection, the Castle procedure has produced the best results for a painful spastic hip dislocation with degenerative changes in the femoral head.29 Using an extraperiosteal dissection, the femoral head is re-sected distal to the lesser trochanter The rectus and vastus lateralis mus-cles are sewn over the remaining femoral shaft, and the gluteal

mus-Sciatic

notch

Anterior-inferior iliac spine

Ischium

Pubis

Bone grafts

Figure 7 Acetabuloplasty technique A, The osteotome is used to open the osteotomy at

the site of maximum deformity (usually posterosuperior), and the largest piece of graft is

placed in this position B, Completed acetabuloplasty, with the graft in place.

Trang 9

cles are interposed between the

fe-mur and the acetabulum Although

the original recommendations

in-cluded 6 weeks of postoperative

skeletal traction, no evidence

sup-ports the necessity of 6 weeks A

few days in traction, with or

with-out a few weeks of abduction

cast-ing or braccast-ing, may be as successful

and more practical Postoperative

pain often persists for 9 to 12 months

before resolving Some surgeons

recommend measures to prevent

heterotopic ossification (HO) In a

series reported by McCarthy et al,4

12 of 56 hips had HO, but all

pa-tients were able to sit The Castle

procedure is contraindicated in

patients who have not reached

skeletal maturity; younger patients

can have excessive proximal

migra-tion of the femoral shaft and

persis-tent pain.4

Another salvage option for

non-ambulatory patients is a

redirection-al osteotomy In a child with severe

adduction but no pain, a valgus

osteotomy (at least 60°) can put the

legs in a more abducted position, allowing for improved perineal care

McHale et al30described a procedure

in which the femoral head is

resect-ed and a subtrochanteric valgus osteotomy is used to direct the lesser trochanter into the acetabulum and the remaining femoral shaft away from the pelvis There was good pain relief in six hips

Other salvage options include arthrodesis and arthroplasty In patients who might be candidates for a Castle procedure but who are skeletally immature, a total shoul-der prosthesis has been used as an interposition arthroplasty31(Fig 9)

In one series of eight arthrodeses, six were considered successful, yet seven patients had complications, including pseudarthrosis in two.32 Root et al32had 13 successful total hip replacements in a series of 15 but noted problems with recurrent dislocations, loosening, bending of the prosthesis, and proximal migra-tion of the greater trochanter More recently, Buly et al33 reported

long-term pain relief and an 86% 10-year survival rate of total hip replace-ments in 18 patients ranging from

16 to 52 years old They used selec-tive tendon releases and spica casts

to reduce the risk of dislocation

HO occurred in 58% of patients but did not seem to have a major clini-cal impact Total hip replacement should be reserved for skeletally mature, highly functional ambula-tors whose hips have advanced degenerative changes precluding reconstruction

Complications

While hip reconstruction or sal-vage carry the attendant risks of any major surgery, additional complica-tions are associated with the

severe-ly involved child Stasikelis et al34 found complications in 68% of pa-tients with gastrostomy or trache-ostomy tubes but in only 12% of those without; complications oc-curred in 29% of nonambulators but

in only 8% of ambulators Compli-cations after hip osteotomy

oc-A

C

B

Figure 8 A, Preoperative anteroposterior radiograph of a

9-year-old patient who had a complete left hip dislocation and pain B,

Both hips were reconstructed (left—comprehensive reconstruc-tion, right—VDRO to balance rotareconstruc-tion, adducreconstruc-tion, and leg

lengths) C, Ten years postoperatively, both hips remained well

reduced and the patient was pain free.

Trang 10

curred in 25% of the 79 patients

studied, with postoperative death in

3 patients Most of these

complica-tions were fractures or decubitus

ulcers, which may be attributable to

postoperative casting In our

expe-rience with more than 400 hip

reconstructions without

postopera-tive casting, there have been no

deaths, and fractures and skin

breakdown are rare even in the

most seriously involved children

Complications after hip surgery

in cerebral palsy can result from the

procedure or the aftercare Matsuo

et al35studied the effect of obturator

neurectomy and found

hyperabduc-tion in the group that had

under-gone neurectomy They and other

investigators stress the importance

of preserving the adductor brevis

muscle and its nerve supply,

espe-cially in ambulatory patients

The reported incidence of

osteo-necrosis of the femoral head in

chil-dren after hip reconstruction ranges

from 0% to 11%.1,19,26 The blood

supply might be compromised either by the femoral osteotomy, as

a result of increased pressure on the femoral head, or during psoas tenot-omy.1 An adequate femoral short-ening may play a key role in pre-vention,1 just as in reconstruction for developmental dysplasia of the hip in older children Fortunately, osteonecrosis rarely has a notably adverse effect on results; in most cases, the hips are still mobile and pain free

HO is commonly seen in radio-graphs within a few months of hip surgery In a review of 192 patients with cerebral palsy, Krum and Miller36noted that HO was particu-larly severe in the few patients who had both hip and spine surgery within a short period of time In the group who had hip adductor length-ening, mild to moderate HO was noted in 21 of 61 patients; however,

2 of 5 patients who had both a spine fusion and hip soft-tissue lengthen-ing had severe, painful HO that

required surgical treatment Unex-plained irritability or motion loss several weeks after surgery may be the first indication of its occurrence Many protocols have been suggested

to prevent HO Anti-inflammatory medications, such as aspirin and in-domethacin, have not been reliable

in preventing HO in patients with cerebral palsy Radiation therapy to the area at risk on the second or third postoperative day (either a sin-gle dose or a divided dose on se-quential days) has been more suc-cessful Occasionally, it can be so debilitating that surgical interven-tion is necessary

Many children with cerebral palsy, particularly nonambulators, have decreased bone density They are at a particularly high risk for insufficiency fractures if their post-operative regimen includes spica casting In the few weeks after cast removal, fractures may occur with transfers or in physical therapy The most common fracture site is the dis-tal femur To decrease the risk of postimmobilization fractures and to minimize stiffness and prolonged loss of function, many centers have abandoned the use of postoperative spica casting altogether Miller et al used immediate mobilization after hip reconstruction and had a 4% fracture rate, much lower than the 10% to 29% noted in patients treated with spica casts.19 Improved nutri-tion, careful therapy, and limited immobilization will help minimize fracture risk in this vulnerable popu-lation

Summary

Managing spastic hip dysplasia is

an important part of caring for chil-dren with cerebral palsy Because the natural history of dislocations is often pain by young adulthood, and because the salvage options at that stage are limited, the goal is careful screening and early treatment Hip

Figure 9 A, Anteroposterior radiograph of a 19-year-old man who had severe pain after

an unsuccessful Girdlestone femoral resection Note the extent of the proximal migration

of the femur B, The same patient 3 years after a total shoulder prosthesis was used as an

interposition arthroplasty The patient remained pain free.

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