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The most common indication for MR imaging of the foot and ankle is for the evaluation of tendon and bone abnormalities, such as osteomyelitis, occult fractures, and partial and complete

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Magnetic resonance (MR) imaging

of the foot and ankle has lagged

behind MR imaging of other joints

in clinical acceptance and utility,

because of the complex anatomy of

the foot and ankle and the need for

small-field-of-view, high-resolution

images Recent advances in both

hardware and software, however,

have made possible the acquisition

of high-resolution images This

feature, combined with the degree

of soft-tissue contrast that can be

achieved with MR imaging and the

ability to obtain images in multiple

planes, has led to the increasing

importance of this modality in

imaging of the foot and ankle for

both diagnosis and surgical

plan-ning It is important that

physi-cians understand the common

clin-ical MR imaging techniques and

their role in evaluating disorders

of the foot and ankle to most

effec-tively utilize this diagnostic

mo-dality

Technique

Because of the complex anatomy of the foot and ankle and the small size of many of its structures, the acquisition of high-resolution im-ages is necessary To obtain such images, the foot and ankle should

be imaged separately by using a surface coil When a comparison view of the unaffected foot is needed

to assess tendon or ligament sym-metry, this should be accomplished

by scanning each foot separately in

a surface coil Attempting to scan both feet together in a body coil or a head coil saves time but at the cost

of having to use a large field of view, which results in low-resolution im-ages that are often nondiagnostic

The optimal field of view of the im-ages should be no larger than 16

cm2, and the matrix should range from 192 x 256 to 256 x 512 Section thickness depends on the pulse sequence used but should be 3 to 4

mm when using spin-echo (SE) se-quences and 1 to 2 mm when using gradient-echo (GRE) sequences For the purpose of MR imaging, the foot and ankle can be divided into three zones: the ankle and hindfoot, the midfoot, and the fore-foot.1 The midfoot is adequately examined by imaging both the hindfoot and the forefoot; there-fore, examination protocols can be further simplified into two zones: ankle-hindfoot and forefoot

To image the hindfoot and ankle, the patient is placed in a supine position with the medial malleolus centered in the coil The foot is allowed to rest in a relaxed posi-tion, generally in 10 to 20 degrees of plantar-flexion and 10 to 30 degrees

of external rotation The foot posi-tion may need to be altered when imaging specific ligaments, such as the calcaneofibular ligament For forefoot examinations, the patient can be either supine or prone with

Dr Recht is Section Head, Outside Imaging, Department of Diagnostic Radiology, Cleve-land Clinic Foundation, CleveCleve-land, Ohio Dr Donley is Staff Surgeon, Department of Ortho-paedic Surgery, Cleveland Clinic Foundation Reprint requests: Dr Recht, Department of Diagnostic Radiology, Cleveland Clinic Foundation, A21, 9500 Euclid Avenue, Cleveland, OH 44195.

Copyright 2001 by the American Academy of Orthopaedic Surgeons.

Abstract

Magnetic resonance (MR) imaging of the foot and ankle is playing an

increas-ingly important role in the diagnosis of a wide range of foot and ankle

abnormali-ties, as well as in planning for their surgical treatment For an optimal MR

study of the foot and ankle, it is necessary to obtain high-resolution,

small-field-of-view images using a variety of pulse sequences The most common indication

for MR imaging of the foot and ankle is for the evaluation of tendon and bone

abnormalities, such as osteomyelitis, occult fractures, and partial and complete

tears of the Achilles, tibialis posterior, and peroneal tendons Magnetic

reso-nance imaging has also been shown to be helpful in the diagnosis of several

soft-tissue abnormalities that are unique to the foot and ankle, such as plantar

fasci-itis, plantar fibromatosis, interdigital neuromas, and tarsal tunnel syndrome.

J Am Acad Orthop Surg 2001;9:187-199 the Foot and Ankle

Michael P Recht, MD, and Brian G Donley, MD

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the toes centered in the coil It is

im-portant to image in all three planes

(transaxial, sagittal, and coronal) for

all indications However, for

ten-don and ligament disorders as well

as for soft-tissue masses, the

trans-axial plane of imaging is the most

useful; most sequences should be

acquired in this plane For bone ab-normalities, particularly those of the talar dome, the sagittal and coronal planes provide the greatest amount

of information

A variety of pulse sequences can

be utilized in the examination of the foot and ankle T1-weighted (short

repetition time [TR]/short echo time [TE]) SE images provide excellent anatomic detail and information about the integrity of the bone mar-row T2-weighted (long TR/long TE) SE images allow detection of the increased water content seen with most pathologic processes as abnor-mal high signal intensity Fast SE T2-weighted sequences have largely replaced conventional SE T2-weighted sequences because of the ability to ob-tain images in a shorter time period with higher resolution Gradient-echo sequences allow the acquisition

of thin contiguous sections that can

be reformatted in multiple planes These sequences have been shown

to be useful in the detection of carti-lage abnormalities.2,3

Short-tau inversion recovery (STIR) imaging is a method of fat suppression that has proved very sensitive in detecting marrow ab-normalities, as well as increased water content in soft tissues.4 Cur-rently, most STIR sequences also use

a variant of the fast SE technique, which allows the images to be ac-quired in a shorter period of time Another method of fat suppression is the use of chemical-selective fat sup-pression, which takes advantage of the differences in resonance

frequen-cy between fat and water protons When evaluating a soft-tissue or osseous mass, T1-weighted chemical-selective fat-suppressed imaging after injection of intravenous con-trast material (e.g., gadolinium– diethylenetriaminepenta-acetic acid [DTPA]) improves the conspicuity

of the mass and facilitates the differ-entiation of a solid soft-tissue mass from a fluid-filled cyst.4 Magnetic resonance arthrography may play a role in the detection of ligament abnormalities and intra-articular bodies and in the staging of osteo-chondral defects.5,6

The foot and ankle can be im-aged with high-field-strength (>0.5-T) or low-field-strength (≤0.5-(>0.5-T) magnets A high-field-strength

Definitions of Radiologic Terms

Chemical-selective The use of chemically selective radio-frequency

fat suppression pulses to eliminate fat signal by taking advantage

of the difference in resonance frequency between fat and water protons

Echo time (TE) The time between the middle of the excitation pulse

and the middle of the spin echo Gradient-echo (GRE) Describing a sequence in which an echo is produced

by a single radio-frequency pulse followed by a gradient reversal

Proton-density- An image acquired with a long TR (e.g., 2,000-3,000

weighted image msec) and a short TE (e.g., 20 msec) to emphasize

differences in proton density and minimize T1 and T2 differences between tissues

Repetition time (TR) The time between successive excitations of a section

Short-tau inversion Describing a sequence that suppresses fat signal by

recovery (STIR) the use of a 180-degree inversion pulse and a short

inversion time Spin-echo (SE) Describing a sequence in which an echo is produced

by a 90-degree radio-frequency pulse followed by one or more 180-degree radio-frequency pulses T1 Spin-lattice or longitudinal relaxation time The

time constant for magnetization to return to the longitudinal axis after application of a radio-frequency pulse

T1-weighted image An image acquired with a short TR (e.g., 400-600

msec) and a short TE (e.g., 10-20 msec) to emphasize differences in T1 relaxation rates between tissues

Fat is of high signal intensity, and fluid is of low signal intensity on T1-weighted sequences

T2 Spin-spin relaxation time The time constant for loss

of phase coherence of a group of spins and the resulting loss in the transverse magnetization signal

T2-weighted image An image acquired with a long TR (e.g., 2,000-3,000

msec) and long TE (e.g., 80-100 msec) to emphasize differences in T2 between tissues Fluid is bright on T2-weighted sequences

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magnet, with its higher

signal-to-noise ratio, allows the acquisition of

high-resolution images in a shorter

time period, thus decreasing the

potential for patient motion In

addition, chemical-selective fat

sup-pression is not available with

low-field-strength magnets

Tendons

Ten tendons cross the ankle joint on

their path from the lower leg into

the foot (Fig 1): the Achilles

ten-don posteriorly; the peroneus

bre-vis and longus laterally; the tibialis

posterior, flexor digitorum longus,

and flexor hallucis longus medially;

and the tibialis anterior, extensor

digitorum longus, extensor hallucis

longus, and peroneus tertius

anteri-orly Tendons are composed

primar-ily of collagen, elastin, and reticulin

fibers

Normal tendons appear as ho-mogeneous low signal intensity on

MR imaging because of their lack

of mobile protons.7 However, on T1-weighted and proton-density-weighted (long TR/short TE) im-ages, normal tendons can have inter-mediate signal intensity because of the “magic angle effect.”8 This effect occurs with short-TE sequences because the signal intensity of struc-tures with poorly hydrated protons, such as tendons, depends in part

on the orientation of the structure

in relation to the main magnetic field When a structure is oriented obliquely in relation to the main magnetic field, its signal intensity is increased on short-TE sequences;

this increase is greatest when the structure is oriented at 55 degrees in relation to the main magnetic field

The increase in signal intensity is not seen on long-TE (T2-weighted) sequences The magic-angle effect is noted in most of the tendons of the foot and ankle as they curve across the ankle to pass into the foot How-ever, this normal increase in signal intensity can usually be differenti-ated from pathologic changes within the tendon if one is aware of the characteristic location of the magic-angle effect, the lack of high signal intensity on T2-weighted images, and the normal morphology of intact tendons

The transaxial plane is the most useful for evaluating the integrity of tendons To obtain a true transaxial image of the tendons that traverse the ankle to pass into the foot, it is necessary to select a plane perpen-dicular to the long axis of the ten-dons as they curve about the ankle (Fig 2) A useful protocol for tendon pathology includes transaxial T1-weighted SE and STIR images or fat-suppressed fast SE T2-weighted images (obtained with the same sec-tion thickness and posisec-tions to allow comparison), coronal T1-weighted, and sagittal fat-suppressed fast SE T2-weighted sequences A sagittal

T1-weighted sequence is added when examining the Achilles tendon Pathologic changes that can be seen in and about tendons on MR imaging include tenosynovitis, tendinopathy, and tendon tears Tenosynovitis is best visualized on T2-weighted images as high-signal-intensity fluid surrounding a normal-appearing tendon (Fig 3) “Ten-dinopathy” or “tendinosis” is the term currently favored to describe tendons that are abnormal but not torn Although some authors still use the term “tendinitis,” studies have not shown a true inflammatory process in tendons.9,10 Rather, histo-logic studies have demonstrated hyperplasia, fibrosis, and vacuolar, mucoid, eosinophilic, and fibrillary degeneration On MR imaging, tendinopathy is characterized by altered tendon morphology,

usual-ly thickening There may also be areas of mildly increased signal intensity on short TE (T1-weighted

or proton-density-weighted) se-quences, but this signal intensity usually decreases on T2-weighted images unless severe tendinopathy

is present

Three MR patterns of tendon rupture have been described.11

Figure 1 Transaxial T1-weighted image

at the level of the distal tibia (T) and fibula

(F) Note the homogeneous low signal

intensity of the tendons A = Achilles

ten-don; ED = extensor digitorum longus; EH

= extensor hallucis longus; FD = flexor

dig-itorum longus; FH = flexor hallucis longus;

PB = peroneus brevis; PL = peroneus

longus; TA = tibialis anterior; TP = tibialis

posterior.

TA

T

F

TP

FD

A

FH

PL PB

EH ED

Figure 2 True transaxial images of the peroneal tendons The sections are graphi-cally prescribed off a sagittal image as the tendons curve around the ankle.

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Type 1 is characterized by

hypertro-phy of the tendon with partial tears

oriented primarily longitudinally

The tendon is enlarged (Fig 4, A),

with foci of increased signal inten-sity on T2-weighted and STIR images (Fig 4, B) Type 2 is characterized

by a partially torn atrophic tendon;

the appearance is of a small tendon with foci of increased signal

intensi-ty on T2-weighted or STIR images (Fig 4, C) Type 3 tears are com-plete tendon ruptures (Fig 4, D)

Although all of the tendons of the foot and ankle can be studied with

MR imaging, the tendons most often associated with injury or dis-ease are the Achilles, tibialis poste-rior, and peroneal tendons

Achilles Tendon

The Achilles tendon is the largest and strongest tendon in the body, ranging in length from 10 to 15 cm

The Achilles tendon does not pos-sess a synovial sheath but rather is invested by loose connective tissue (peritenon) The normal Achilles tendon appears as homogeneously low signal intensity on all pulse sequences1(Fig 5, A and B) It has

a flat or concave anterior margin on transaxial images, giving it a cres-centic shape At its insertion onto

the calcaneus, the tendon becomes more ovoid, with a flattened anterior margin

Acute peritendinitis is manifested

by loss of the sharp interface be-tween the tendon and the pre-Achilles fat, with high signal inten-sity on T2-weighted and STIR images about the tendon, but with preservation of the low signal in-tensity of the tendon itself Chronic Achilles tendinopathy has the appearance of a thickened enlarged tendon (Fig 5, C and D) There may be increased signal intensity within the tendon on T1-weighted and proton-density-weighted im-ages, but the signal usually de-creases in intensity on T2-weighted and STIR images Although mea-surements of the thickness of the Achilles tendon have been pub-lished (normal, <8 mm),1 careful assessment of the anterior margin

of the tendon on transaxial views may be more useful Loss of the normal concave margin of the ante-rior aspect of the tendon is a sign that the tendon is thickened and abnormal

Figure 3 Tenosynovitis of the flexor

hallu-cis tendon Note the high-signal-intensity

fluid (arrows) surrounding the normal

low-signal-intensity tendon and the

metal-lic artifact about the tibia secondary to

pre-vious hardware placement.

Figure 4 Patterns of tendon rupture A, Type 1 tear of the tibialis posterior tendon Transaxial T1-weighted image at the level of the sustentaculum tali demonstrates an enlarged, irregularly shaped tibialis posterior tendon (arrow) B, Transaxial STIR image of the same ankle demonstrates high signal intensity within the enlarged tibialis posterior tendon (arrows) C, Type 2 tear of the tibialis posterior

ten-don Transaxial T1-weighted image demonstrates a small atrophic tibialis posterior tendon (white arrows) approximately half the

diame-ter of the flexor digitorum tendon (black arrow) D, Type 3 tear of the Achilles tendon Sagittal T2-weighted fast SE image demonstrates

discontinuity of the Achilles tendon There is retraction of the torn edge of the tendon (arrows) and high signal intensity in the gap between the tendon edge and the calcaneus.

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Ruptures of the Achilles tendon

most frequently occur 3 to 4 cm

above its insertion onto the

calca-neus.7 The MR findings of a partial

rupture include focal areas of high

signal intensity on T2-weighted

and STIR images within the tendon

substance but with preservation of

some tendon continuity4(Fig 5, E

and F) Acute complete ruptures

demonstrate loss of tendon

conti-nuity, with the gap in the tendon

appearing as an area of high signal

intensity on T2-weighted and STIR

images, representing blood or

ede-ma4 (Fig 4, D) In chronic

com-plete ruptures, the gap may be

filled with low-signal-intensity

fibrotic tissue

Tibialis Posterior Tendon

Tibialis posterior tears are most

commonly seen in middle-aged

women, who present with an

ac-quired, painful flatfoot; these are

generally chronic tears.11,12 The

tib-ialis posterior tendon is the most

medial tendon in the posterior

com-partment at the level of the ankle

The tendon continues into the foot,

where it inserts onto the navicular,

A

C

E

B

D

F

Figure 5 A and B, Normal Achilles

ten-don A, On T1-weighted sagittal image,

the normal Achilles tendon is of

homoge-neous low signal intensity and has sharp

interfaces with the surrounding soft tissue.

B, Transaxial T1-weighted image at the

level of the distal Achilles tendon The

concave anterior surface of the tendon

gives a crescentic shape to the distal

por-tion (arrowheads) C and D, Chronic

tendinopathy of the Achilles tendon

T2-weighted sagittal (C) and T1-T2-weighted

transaxial (D) images demonstrate a

thick-ened Achilles tendon (arrows), which is of

low signal intensity Note the loss of the

normal concave anterior surface of the

ten-don on the transaxial image E and F,

Partial tear of the distal Achilles tendon.

T1-weighted (E) and T2-weighted (F)

sagit-tal images demonstrate an enlarged,

thick-ened distal Achilles tendon On the

T2-weighted image, there is high signal

insity (arrow) within the distal Achilles

ten-don, representing a partial tear.

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medial cuneiform, metatarsal bases,

and sustentaculum tali The normal

tibialis posterior tendon has

homo-geneously low signal intensity

ex-cept for its most distal segment,

which may demonstrate

intermedi-ate signal intensity on T1-weighted

sequences It should be twice the

diameter of the flexor digitorum

longus and flexor hallucis longus

tendons distal to the level of the

medial malleolus.12

Type 1 tears of the posterior

tib-ialis tendon, which are the most

common type of tear, are manifested

by an enlarged tendon, which may

be four to five times the size of the

flexor digitorum tendon (Fig 4, A

and B) There is increased signal

intensity within the tendon on

short-TE images, which often remains

high on T2-weighted and STIR

images Type 2 tears present as a

smaller than normal tendon, often

the same size as or smaller than the

flexor digitorum longus (Fig 4, C)

Type 3 tears are complete tendon

ruptures

Peroneal Tendons

The peroneus longus and brevis tendons occupy a common synovial sheath up to the level of the calca-neocuboid joint, beyond which the sheath bifurcates At the level of the lateral malleolus, the peroneus bre-vis tendon is anteromedial or ante-rior to the peroneus longus tendon

The posterior edge of the fibula is normally concave in this region, forming a groove within which the tendons lie The tendons are kept within this groove by the superior peroneal retinaculum

On MR imaging, normal peroneal tendons are of similar size and ho-mogeneous low signal intensity

The peroneus longus tendon is ovoid, but the peroneus brevis ten-don may have a flattened appear-ance in the retromalleolar groove

The superior peroneal retinaculum

is usually identifiable as a discrete structure

Although complete ruptures of the peroneal tendons are uncom-mon, longitudinal splits of the

per-oneus brevis tendon have been increasingly recognized.13-15 Longi-tudinal splits are thought to be caused by either forced dorsiflexion

or repetitive peroneal subluxation, which leads to compression of the peroneal brevis against the posterior aspect of the fibula Interposition of the peroneus longus between the portions of the split peroneus brevis tendon can occur On MR imaging,

a split peroneus brevis appears either as a C-shaped structure at or below the level of the lateral malleo-lus, which partially wraps around the peroneus longus tendon, or as a completely bisected tendon (Fig 6, A) There may or may not be in-creased signal intensity within the tendon An osseous ridge at the lat-eral margin of the fibula has been associated with a split peroneus bre-vis tendon, and is considered to rep-resent changes secondary to repeti-tive subluxation of the peroneal ten-dons.13 Other MR findings that are associated with, and may predispose

to, splitting of the peroneus brevis

Figure 6 Lesions of the peroneal tendons A, Transaxial T1-weighted image obtained just distal to the lateral malleolus demonstrates a completely bisected peroneus brevis tendon (arrowheads) T1-weighted transaxial (B) and coronal (C) images show subluxation of the

peroneal tendons (arrows) so that they lie lateral to the malleolus, rather than posterior to it.

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tendon include a flat or convex

fibu-lar groove, a ligamentous tear, or

the presence of a peroneus quartus

muscle or the low-lying belly of the

peroneus brevis muscle.14

Traumatic peroneal subluxation

or dislocation is associated with

dis-ruption of the superior retinaculum

or stripping of the periosteum at its

attachment onto the fibula This is

not an uncommon injury in athletes

and may be misdiagnosed as an

ankle sprain.7 Traumatic dislocation

can also be seen with calcaneal

frac-tures The abnormally positioned

peroneal tendons are easily seen on

MR images lying lateral (Fig 6, B

and C), or in extreme cases anterior,

to the lateral malleolus

Ankle Ligaments

Magnetic resonance imaging can

demonstrate both intact (Fig 7) and

abnormal (Fig 8) ankle ligaments

However, its role in the evaluation

of ankle ligament injuries remains

uncertain, especially in cases of

acute ligament injury, which are

most often diagnosed on clinical

examination It may play a limited

role in defining which ligaments

are injured, the extent of such

in-jury in patients with chronic ankle

instability, and the presence of

os-teochondral injuries of the talar

dome in patients with chronic ankle

pain after ligament injuries

The ankle ligaments can be

grouped into three complexes: the

lateral complex, consisting of the

anterior talofibular, posterior

talo-fibular, and calcaneofibular

liga-ments; the deltoid ligament, which

has several components; and the

syndesmotic complex, composed of

the interosseous membrane, the

anterior and posterior tibiofibular

ligaments, and the transverse

tibio-fibular ligament To evaluate these

ligaments with MR imaging, it is

necessary to image them in a plane

parallel to their long axes This

plane varies for the different liga-ments, but a cadaveric study of the ankle ligaments demonstrated that particular planes were optimal for studying the various ligaments.16,17

The transaxial plane with the foot positioned in 10 to 20 degrees of dorsiflexion provides the best visual-ization of the anterior and posterior talofibular ligaments; the anterior,

A

C

B

D Figure 7 Appearance of normal ankle ligaments A, The intact anterior talofibular

liga-ment (arrowheads) is of low signal intensity on this T1-weighted transaxial image Note

the elliptical shape of the talus and the presence of the lateral malleolar fossa B, Intact

anterior (arrowheads) and posterior (arrows) tibiofibular ligaments are of uniform low sig-nal intensity The medial border of the lateral malleolus is flattened, indicating that this is

the level of the tibiofibular ligaments C, Intact tibiotalar component of the deltoid (arrow-heads) Note the osteochondral defect of the lateral talar dome D, Posterior talofibular

ligaments (arrowheads) on T1-weighted coronal image The deltoid and posterior talofibular ligaments have a striated appearance, rather than a homogeneous low-signal-intensity appearance like the anterior talofibular ligament.

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transverse, and posterior

tibiofibu-lar ligaments; and the various

com-ponents of the deltoid ligament

Coronal images allow visualization

of the full length of most of the

com-ponents of the deltoid ligament The

calcaneofibular ligament is best seen

on transaxial images with the foot in

40 to 50 degrees of plantar-flexion

It is difficult to image the foot in

all of these positions in a reasonable

time period Most MR examinations

of the foot and ankle are done in 10

to 20 degrees of plantar-flexion,

which is not ideal for imaging any of

the ankle ligaments Therefore, it is

important to clearly communicate in

advance which specific ligamentous

complexes need to be imaged The

MR sequences used to evaluate the

ankle ligaments include T1-weighted

SE, T2-weighted fast SE, and STIR

sequences In cases of chronic ankle

instability, MR arthrography may

also be useful

Normal ligaments are thin and of

low signal intensity on all MR pulse

sequences Occasionally, they have

a striated appearance, especially the deltoid and posterior talofibular and tibiofibular ligaments.18 Be-cause of the oblique course of the tibiofibular ligaments, the talus may

be seen on images demonstrating their fibular attachments This can lead to misidentification of the tibiofibular ligaments as the talo-fibular ligaments The best way to avoid this mistake is to identify the insertion of the ligaments The shape of the talus and the fibula in the transaxial plane can also be used

to correctly identify the two sets of ligaments.8 At the level of the tibio-fibular ligaments, the talus is rectan-gular, and the medial border of the fibula is flattened At the level of the talofibular ligaments, the talus is more elongated, the sinus tarsi is usually visible, and there is a deep indentation along the medial border

of the lateral malleolus (the malleo-lar fossa)

The MR findings in ligament injuries include complete tear of the ligament, ligament waviness or lax-ity, thickening or irregularity of the ligament, increased signal intensity within the ligaments, edema and hemorrhage about the ligament, and abnormal increased fluid

with-in the jowith-int and surroundwith-ing ten-dons.7,17 In cases of chronic insta-bility, some of the ancillary findings

of ligament injury, such as edema and hemorrhage and joint effusions, may not be present

Magnetic resonance arthrography has been shown to be more sensitive and more accurate than conventional

MR imaging in this situation.5 This

is because the torn, scarred ligament

is closely applied to the bone and is better visualized when separated from the bone by the intra-articular injection of contrast material (Gd-DTPA) In addition, contrast extra-vasation through the torn ligament into the surrounding soft tissues serves as convincing evidence of dis-ruption of the ligament

Bones

Infection

Infection of the bones of the foot and ankle occurs most commonly in diabetic patients, usually due to direct extension of soft-tissue infec-tion Magnetic resonance images, especially STIR and fat-suppressed T1-weighted images acquired after intravenous contrast administration effectively depict the bone marrow changes that occur with osteomye-litis.19 However, these changes are not specific for osteomyelitis The differentiation of bone marrow changes due to infection from those due to edema or neuropathy has proved challenging

Although neuropathic tissue may

be visualized as low signal intensity

on all pulse sequences,20it may have a high-signal-intensity appear-ance on T2-weighted and STIR sequences.7 Enhancement after intravenous contrast administration

is also not specific, as it can be seen

in the presence of any process result-ing in increased vascular

permeabili-ty Findings useful in the diagnosis

of osteomyelitis include soft-tissue changes that extend to the skin surface adjacent to bone-marrow changes, cortical disruption, and periosteal abnormalities (Fig 9).4,7 Nonetheless, it is still often difficult

to reliably differentiate neuropathy from infection on MR imaging A useful protocol for the evaluation of osteomyelitis includes T1-weighted

SE, STIR, and fat-suppressed T1-weighted SE images obtained after contrast administration The images are acquired in at least two planes, which are determined on the basis

of the site of the suspected infection

Fractures

Magnetic resonance imaging has little role to play in the evaluation of acute traumatic bone injuries, as they are usually easily diagnosed on conventional radiography How-ever, MR imaging may be useful in

Figure 8 Chronic tear of the anterior

talofibular ligament This transaxial

T2-weighted image demonstrates the absence

of the anterior talofibular ligament, with

high-signal-intensity fluid (arrows) filling

the expected location of the ligament.

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identifying bone contusions, occult

nondisplaced fractures, and stress

fractures and stress reactions in the

foot and ankle Metatarsal stress

fractures can generally be

diag-nosed without MR imaging In

con-trast, stress fractures of other tarsal

bones, such as the navicular,

cunei-forms, and calcaneus, often present

as foot pain of unknown etiology If

conventional radiographs appear

normal, MR imaging is a valuable

modality, as it can depict pathologic

changes in both bone and soft tissue

Stress fractures are diagnosed most

readily on STIR and T1-weighted

SE images but can also be seen on

T2-weighted images (Fig 10) On

T1-weighted images, stress fractures

appear as a linear area of low signal

intensity compared with normal

bone marrow surrounded by a more

diffuse area of slightly higher, though

still low, signal intensity.20-22 On STIR

images, the linear component

re-mains of low signal intensity, but the

surrounding area is of high signal

intensity, consistent with bone

mar-row edema

In addition to stress fractures, MR imaging is also able to depict stress responses, which represent early changes in bone before the develop-ment of a fracture.22 Stress responses are characterized by globular areas of low signal intensity on T1-weighted images, which increase in signal intensity on STIR sequences They can be differentiated from fractures

by the lack of a linear component

Stress responses appear similar to bone bruises but can be differen-tiated from them by the lack of an antecedent acute traumatic event

Osteochondral Injuries

of the Talar Dome

Osteochondral injuries of the talar dome occur most commonly in the second to fourth decades of life and affect both the medial and lat-eral aspects of the dome.23 Most lesions are apparent on conventional radiographs; however, MR imaging can depict lesions too small to be seen on plain films and may be use-ful in evaluating the extent of the lesion and the stability of the

frag-ment.23 Increased signal intensity separating the lesion from the un-derlying bone on T2-weighted or STIR images is the most frequent

MR sign of instability, but this ap-pearance has also been reported in stable lesions.24 Other less fre-quently seen signs of instability are cartilage fractures, focal cartilage defects, and underlying cysts.24 Magnetic resonance arthrogra-phy has been shown to be more accurate in evaluating the stability

of the fragment than conventional

MR imaging in osteochondral le-sions of the knee,6because of the ability to see contrast material tra-versing the overlying cartilage de-fect and encircling the loose frag-ment More recently, cartilage-specific sequences, such as fat-suppressed T1-weighted GRE sequences, have been used to evaluate the overlying cartilage (Fig 11) Although MR imaging is highly accurate for eval-uating the cartilage in the knee,2,3

Figure 9 Osteomyelitis of the calcaneus A, Sagittal T1-weighted image demonstrates a

soft-tissue ulcer (white arrow) on the plantar surface of the foot adjacent to the area of

abnormal low signal intensity within the calcaneus (black arrows) B, Sagittal

fat-suppressed T1-weighted image shows enhancement (arrows) of the calcaneus and adjacent

soft tissues, as well as subtle cortical disruption (lower arrow).

Figure 10 Stress fracture of the navicular Coronal T2-weighted image demonstrates high signal intensity within the navicular surrounding a thin linear area of low signal intensity (arrowheads), which represents the fracture line.

Trang 10

evaluation of talar cartilage has

been more difficult, even with both

sagittal and coronal images, because

the talar cartilage is considerably

thinner

Bone Tumors

Although MR imaging is very

sensitive in the detection of bone

tumors, it frequently lacks

specific-ity However, MR imaging can be

useful in evaluating the extent of

the tumor and the presence of an

associated soft-tissue mass The

imaging is done in all three planes

with a combination of T1-weighted

SE, STIR, and T2-weighted fast

SE sequences Occasionally, a

fat-suppressed T1-weighted sequence

is used after administration of

in-travenous contrast material, as it

increases the conspicuity of the

bone and soft-tissue abnormalities

and improves the differentiation of

necrotic tissue from viable tumor.25

In addition, some researchers have

suggested that dynamic

contrast-enhanced MR imaging may be

use-ful in assessing the response of

osteosarcoma and Ewing’s sarcoma

to chemotherapy.25,26

Associated Soft-Tissue Conditions

Plantar Fasciitis

The deep plantar fascia, or plan-tar aponeurosis, is a multilayered fibrous structure, subcutaneous in location, which extends as a thick, strong, dense tissue from the calca-neus posteriorly to the region of the metatarsal heads and beyond

Plantar fasciitis is one of the causes

of painful heel syndrome and may

be secondary to mechanical, degen-erative, or systemic conditions The plantar fascia is best visual-ized on sagittal and coronal images and normally should be 3 to 4 mm thick and of homogeneously low signal intensity on all pulse se-quences.27 In patients with plantar fasciitis, the plantar fascia is thick-ened (7 to 8 mm thick) and demon-strates areas of increased signal intensity on T2-weighted and STIR sequences4,27 (Fig 12) There fre-quently is also abnormally increased signal intensity in the adjacent sub-cutaneous tissue Increased signal intensity may also be seen in the cal-caneus at the insertion site of the plantar fascia, presumably second-ary to reactive edema

Plantar fasciitis is a clinical diag-nosis and rarely, if ever, warrants

MR imaging However, in patients with a painful heel syndrome, it can occasionally be helpful in excluding other etiologic possibilities, such as calcaneal stress fractures and tarsal tunnel masses

Plantar Fibromatosis

Plantar fibromatosis is character-ized by fibrous proliferation in the plantar fascia.4 An association be-tween plantar fibromatosis and other conditions associated with proliferation of fibrous tissue, such

Figure 11 Osteochondral injury of the talar dome A, T1-weighted coronal image

demon-strates deformity of the talar dome, with a focal area of low signal intensity within the

bone marrow of the talar dome (arrows) B, Fat-suppressed three-dimensional GRE

coro-nal image depicts articular cartilage as high sigcoro-nal intensity There is disruption of the

articular cartilage (arrows) overlying the signal abnormality within the talar dome.

Figure 12 Plantar fasciitis A, T1-weighted sagittal image shows thickened deep plantar

fascia at its insertion onto the calcaneus (arrow) There is also abnormal intermediate

sig-nal intensity within the deep plantar fascia B, Sagittal STIR image demonstrates abnormal

high signal intensity about the deep plantar fascia (arrow).

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