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Case presentation: We report a case of a spontaneous ilio-iliac arteriovenous fistula in a 68-year-old Caucasian man detected following presentation with unilateral claudication and cong

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C A S E R E P O R T Open Access

Hybrid management of a spontaneous ilio-iliac arteriovenous fistula: a case report

Gavin C O ’Brien*

, Colm Murphy, Zenia Martin, Naseem Haider, Mary P Colgan, Dermot Moore, Prakash Madhavan and Sean M O ’Neill

Abstract

Introduction: Spontaneous iliac arteriovenous fistulae are a rare clinical entity Such localized fistulation is usually a result of penetrating traumatic or iatrogenic injury Clinical presentation can vary greatly but commonly includes back pain, high-output congestive cardiac failure and the presence of an abdominal bruit Diagnosis, therefore, is often incidental or delayed

Case presentation: We report a case of a spontaneous ilio-iliac arteriovenous fistula in a 68-year-old Caucasian man detected following presentation with unilateral claudication and congestive cardiac failure Following

computed tomography evaluation, the fistula was successfully treated with a combined endovascular (aorto-uni-iliac device) and open (femoro-femoral crossover) approach

Conclusion: Endovascular surgery has revolutionized the management of such fistulae and we report an

interesting case of a high-output iliac arteriovenous fistulae successfully treated with a hybrid vascular approach

Introduction

Spontaneous iliac arteriovenous fistulae (AVF) are a rare

clinical entity Such localized fistulation is usually a

result of penetrating traumatic or iatrogenic injury [1]

Clinical presentation can vary greatly but commonly

includes back pain, high-output congestive cardiac

fail-ure (CCF) and the presence of an abdominal bruit

Diagnosis, therefore, is often incidental or delayed [2]

Case presentation

A 68-year-old Caucasian man was referred to our

out-patients clinic following the incidental discovery of a 6

× 8 cm distended iliac vessel whilst having an

ultra-sound for surveillance of liver cirrhosis His clinical

his-tory revealed a progressive hishis-tory of right flank pain,

worsening right leg claudication and a persistently cold

sensation in his right foot He also complained of

pro-gressive breathlessness on exertion, clinically suggestive

of deteriorating CCF There was no history of trauma or

previous surgery Ankle-brachial pressure measurements

revealed a reduced index of 0.76 on the right, and a

nor-mal index of 1.35 on the left with corresponding toe

pressures of 55 mmHg and 143 mmHg respectively A contrast enhanced computed tomography (CT) scan showed an isolated right common iliac artery (CIA) to right common iliac vein AVF (Figure 1) His aorta was normal in caliber, measuring 19 mm at the aortic bifur-cation The aneurysmal segment began immediately dis-tal to the aortic bifurcation at the origin of the right CIA, with no normal segment of CIA evident The aneurysm measured 9.4 cm in maximal diameter and extended to within 17 mm of the right iliac bifurcation

It was impossible to differentiate the arterial wall from the venous wall in the aneurysmal segment on either ultrasound or CT scans His inferior vena cava (IVC) was grossly distended with a uniform diameter of 36

mm in its full course

Pre-operative discussions focused on finding an endo-vascular strategy to solve the problem As no normal caliber proximal right CIA existed, an isolated iliac cov-ered stent was impossible as no proximal sealing zone existed This required sealing a proximal stent in his aorta Bifurcated endografts have been used to seal ilio-iliac fistulae previously [1] The aortic bifurcation dia-meter was 19 mm in this case and although some devices have reported success negotiating smaller aortic bifurcations [2], we felt an aorto-bi-iliac graft would be

* Correspondence: gavinobrien@rcsi.ie

St James ’ Hospital Vascular Department, St James’ Hospital, Dublin 6, Ireland

© 2011 O ’Brien et al; licensee BioMed Central Ltd This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in

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in danger of being compressed at the bifurcation with a

high risk of occlusion As a result, a hybrid approach

with deployment of an aorto-uni-iliac (AUI) device

fol-lowed by a femoro-femoral bypass was planned Our

patient was operated upon in our endovascular suite

(Siemens) under spinal anesthesia Both common

femoral arteries (CFA) were controlled and cannulated

with 6Fr sheaths (Johnston & Johnston) His aorta was

cannulated with a 0.035 wire Bentson wire (Cook

Medi-cal, Bloomington, IN, USA) via each CFA with the

assis-tance of an angled catheter (Kumpe, Cook Medical) A

diagnostic flush pigtail catheter was placed in his aorta

via the contralateral limb A stiff 0.035 Amplatz wire

(Amplatz Super Stiff, Boston Scientific) was exchanged

as access to the ipsilateral limb Following an angiogram

to confirm renal anatomy, an aorto-uni-iliac device

(Zenith Renu, Cook Medical) was deployed from

imme-diately below his renal arteries to his mid right external

iliac artery, thus occluding his right internal iliac artery

A 14 × 10 mm Amplatzer occlusion device (AGA

Medi-cal Corp, MN, USA) was deployed via the contralateral

limb to his proximal left CIA A completion angiogram

confirmed exclusion of the ilio-iliac AVF A right to left

femoro-femoral bypass with 8 mm

polytetrafluoroethy-lene (PTFE) was performed to re-establish flow to his

left leg as well as providing left internal iliac perfusion

On the first postoperative day, the mass was no longer

pulsatile and the machinery-like murmur in the right

iliac fossa was absent A CT scan on postoperative day

two confirmed a patent AUI endovascular graft and

patent femoro-femoral bypass, as well as confirming exclusion of contrast from the right iliocaval system (Figure 2) His right foot no longer felt cool and the postoperative ankle brachial index (ABI) confirmed an index of 1.05 on the right and 0.95 on the left, with cor-responding toe pressures of 119 mmHg and 117 mmHg respectively He was discharged after seven days without complication At a clinic one month later, his claudica-tion had resolved completely and he no longer had symptoms suggestive of CCF A duplex ultrasound con-firmed exclusion of arterial flow from the iliocaval vessels

Discussion

Penetrating traumatic injury remains the most common cause of abdominal and pelvic arteriovenous fistulae [3] This trauma may be malicious but is frequently iatro-genic, commonly occurring after lumbosacral laminect-omy whereupon penetration of the anterior longitudinal

Figure 1 Preoperative CT Preoperative contrast-enhanced CT 3-D

reconstruction with arrow demonstrating the 8 cm ilio-iliac AV

fistula originating from the proximal right CIA.

Figure 2 Postoperative CT Postoperative CT 3-D reconstruction showing endovascular exclusion of the AV fistula with an aorto-uni-iliac graft (white arrow) and a functioning right to left femoro-femoral cross-over bypass (red arrow).

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ligament by dissecting instruments can injure the aorta,

IVC or iliac vessels, depending on the level of the

lami-nectomy [4] Linton and White first reported such a

case in 1945 [5] Case reports also exist of fistulation

following aortic aneurysm surgery and even after

laparo-scopic appendectomy [6] Post-traumatic AVFs may

pre-sent many years after the initial injury, some reporting a

traumatic history as distant as 30 to 52 years previously

[7] In such cases, the remote injury in combination

with the diverse and subtle modes of presentation can

result in delayed or overlooked diagnosis of the fistula

Typical symptoms include back pain (70%) and

progres-sive sequelae from high output CCF (such as

orthop-noea, edema and fatigue) [4] An abdominal bruit is

commonly demonstrable (80%) Our patient reported

unilateral, progressive leg claudication, confirmed with

unilaterally reduced ABI and toe pressure readings This

reflected a steal phenomenon which was subsequently

fully reversed following exclusion of the AVF To the

best of our knowledge, this interesting phenomenon has

not previously been described

Treatment of iliac AVFs in the open vascular surgical

era was fraught with danger, with reported surgical

mor-tality rates of 9-34% Operative blood loss of six liters

was common [8] Acute presentations with spontaneous

ruptures are thankfully rare (less than 4% of ruptured

aneurysms [9]) but carry a significantly higher mortality

rate

Conclusion

The evolution of endovascular surgery has led to a

para-digm shift in the approach to managing aneurysmal

dis-ease with a concomitant vast reduction in mortality and

morbidity rates The first endovascular exclusion of an

iliocaval fistula appeared in 1995 [10] We add to the

lit-erature this report of a successful endovascular

exclu-sion of a giant, spontaneous, ilio-iliac AVF Our case

demonstrates several aspects of modern day vascular

surgery such as the importance of preoperative imaging

and planning, as well as the emerging role for a hybrid

endovascular and open surgical approach to minimize

operative morbidity as well as optimize long-term

suc-cess for such complex vascular pathology

Consent

Written informed consent was obtained from the patient

for publication of this case report and any

accompany-ing images A copy of the written consent is available

for review by the Editor-in-Chief of this journal

Authors ’ contributions

GOB was the main author, treated our patient, researched the topic and

coordinated the editing of the paper CM & ZM were major contributors to

researching, writing and editing the paper NH, MPC, PM, DM & SON were

all involved in making treatment decisions regarding our patient as well as reading, making editorial suggestions and approving the final manuscript All authors read and approved the final manuscript.

Competing interests The authors declare that they have no competing interests.

Received: 5 January 2011 Accepted: 22 August 2011 Published: 22 August 2011

References

1 Sarmiento JM, Wisniewski PJ, Do NT, Vo TD, Aka PK, Tayyarah M, Hsu JH: Bifurcated endograft repair of ilio-iliac arteriovenous fistula secondary to lumbar diskectomy Ann Vasc Surg 2010, 24(4):551e.13-7.

2 Wang G, Carpenter JP: The powerlink bifurcated system for endovascular aortic aneurysm repair: six-year results J Vasc Surg 2008, 48:535-545.

3 Cronin B, Kane J, Lee W, Shriki J, Weaver FA: Repair of a high-flow iliac arteriovenous fistula using a thoracic endograft J Vasc Surg 2009, 49:767-770.

4 Krishna M, Theodore S, Varma PK, Neelakandhan KS: Spontaneous iliac arteriovenous fistula: recognition and management J Cardiovasc Surg

2005, 46:181-182.

5 Linton RR, White PD: Arteriovenous fistula between the right common iliac artery and inferior vena cava: report of a case following operation for a ruptured intervertebral disc Arch Surg 1945, 50:6-13.

6 Keuhnl A, Zimmermann A, Pongratz J, Eckstein HH: Young girl presenting with heart failure 5 years post laparoscopic appendicectomy Case report of an ilio-iliac AV fistula Eur J Vasc Endovasc Surg 2010, 40(1):107-109.

7 Chaudry M, Finn WR, Kim K, Neschis DG: Traumatic arteriovenous fistula

52 years after injury J Vasc Surg 2010, 51(5):1265-1267.

8 Brewster DC, Cambria RP, Moncure AC, Darling RC, LaMuraglia GM, Geller SC, Abbott WM: Aortocaval and iliac arteriovenous fistulas: recognition and treatment J Vasc Surg 1991, 13(2):253-264.

9 Bertinchant JP, Nigond J, Dauzat M, Ovtchinnikoff S, Noblet D, Arnaud E, Bengler C, Arich C, Lopez FM, Hertault J: Arteriovenous fistula caused by spontaneous rupture of an aortic or iliac aneurysm in the iliocaval venous system Arch Mal Coeur Vaiss 1992, 85(1):91-94.

10 Zajko AB, Little AF, Steed DL, Curtiss EI: Endovascular stent graft repair of common iliac artery to inferior vena cava fistula J Vasc Interv Radiol 1995, 6:803-806.

doi:10.1186/1752-1947-5-401 Cite this article as: O’Brien et al.: Hybrid management of a spontaneous ilio-iliac arteriovenous fistula: a case report Journal of Medical Case Reports 2011 5:401.

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