Polycythemia Vera and Other Myeloproliferative Diseases Part 7 Table 103-4 Risk Stratification for Idiopathic Myelofibrosis A.. Prognostic factorsa Hemoglobin 30,000/µL Number of pro
Trang 1Chapter 103 Polycythemia Vera and Other
Myeloproliferative Diseases
(Part 7)
Table 103-4 Risk Stratification for Idiopathic Myelofibrosis
A Prognostic factorsa
Hemoglobin <10 gm%
White cell count < 4000/µL or > 30,000/µL
Number of prognostic
factors
Risk group Median survival
(months)
Trang 20 Low 93
Hemoglobin < 10 gm%
Constitutional
symptoms
Blast cells > 1%
Number of prognostic
factors
Risk group Median survival
(months)
Trang 3C Prognostic
factorsc
Median survival (months)
Age <65 years
Hemoglobin ≤10 gm%
Karyotype: Normal 54
Abnormal 22
Age <65 years
Hemoglobin >10 gm%
Karyotype: Normal 180
Abnormal 72
Age >65 years
Trang 4Hemoglobin ≤10 gm%
Karyotype: Normal 44
Abnormal 16
Age >65 years
Hemoglobin >10 gm%
Karyotype: Normal 70
Abnormal 78
a
From B Dupriez et al Blood 88:1013, 1996
b
From F Cervantes et al Br J Haematol 102:684, 1998
c
From JT Reilly et al Br J Haematol 98:96, 1997