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Tiêu đề Surface Tailoring of Cellulose Aerogel-Like Structures with Ultrathin Coatings Using Molecular Layer-by-Layer Assembly
Tác giả Zhaleh Atoufi, Michael S. Reid, Per A. Larsson, Lars Wøgberg
Trường học KTH Royal Institute of Technology
Chuyên ngành Fiber and Polymer Technology
Thể loại journal article
Năm xuất bản 2022
Thành phố Stockholm
Định dạng
Số trang 14
Dung lượng 9,5 MB

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Nội dung

Cellulose nanofibril-based aerogels have promising applicability in various fields; however, developing an efficient technique to functionalize and tune their surface properties is challenging. In this study, physically and covalently crosslinked cellulose nanofibril-based aerogel-like structures were prepared and modified by a molecular layer-by-layer (m-LBL) deposition method.

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Carbohydrate Polymers 282 (2022) 119098

Available online 10 January 2022

0144-8617/© 2022 The Authors Published by Elsevier Ltd This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/)

Surface tailoring of cellulose aerogel-like structures with ultrathin coatings

using molecular layer-by-layer assembly

aDivision of Fibre technology, Department of Fiber and Polymer Technology, KTH Royal Institute of Technology, Teknikringen 56–58, SE-100 44 Stockholm, Sweden

bKTH Royal Institute of Technology, Department of Fiber and Polymer Technology, Wallenberg Wood Science Center (WWSC), Stockholm, Sweden

A R T I C L E I N F O

Keywords:

Cellulose nanofibril

Aerogels

Molecular layer-by-layer deposition

Surface functionality

Wet strength

Oil absorption

A B S T R A C T Cellulose nanofibril-based aerogels have promising applicability in various fields; however, developing an effi-cient technique to functionalize and tune their surface properties is challenging In this study, physically and covalently crosslinked cellulose nanofibril-based aerogel-like structures were prepared and modified by a mo-lecular layer-by-layer (m-LBL) deposition method Following three m-LBL depositions, an ultrathin polyamide layer was formed throughout the aerogel and its structure and chemical composition was studied in detail Analysis of model cellulose surfaces showed that the thickness of the deposited layer after three m-LBLs was approximately 1 nm Although the deposited layer was extremely thin, it led to a 2.6-fold increase in the wet specific modulus, improved the acid-base resistance, and changed the aerogels from hydrophilic to hydrophobic making them suitable materials for oil absorption with the absorption capacity of 16–36 g/g Thus, demon-strating m-LBL assembly is a powerful technique for tailoring surface properties and functionality of cellulose substrates

1 Introduction

Substituting petroleum-derived, non-biodegradable materials with

sustainable and biodegradable materials from renewable sources is of

great scientific and economic interest (Aalbers et al., 2019) In this

re-gard, bio-based, sustainable aerogels are considered as promising

ma-terials for a wide range of applications, including thermal and acoustic

insulations (Eskandari et al., 2017; Nguyen et al., 2020), adsorption of

liquids and gases (Jatoi et al., 2021), energy storage (Sun et al., 2021),

drug carriers (Liu et al., 2021) and catalyst supports (Gu et al., 2021)

Aerogels can be prepared from many different sources, such as carbon

nanomaterials (Khoshnevis et al., 2018; Pruna et al., 2019), cellulosic

nanomaterials such as cellulose nanofibrils (CNFs) and cellulose

nano-crystals (CNCs) (Cervin et al., 2012; De France et al., 2017), synthetic

polymers (Wu et al., 2019), and silica-based materials (He et al., 2018)

Among these, CNF-based aerogels, here defined as lightweight materials

derived from deaerated CNF gels, have attracted great attention due to

the intrinsic properties of CNFs, such as high mechanical strength, high

aspect ratio, bio-degradability, and their green preparation process

Moreover, due to the numerous hydroxyl groups, CNFs can be

func-tionalized with various functional groups, leading to diverse properties

that can be tailored to the desired application (Tavakolian et al., 2020)

In order to achieve CNF-based aerogels with particular physical and chemical properties, CNFs can either be pre-functionalized before forming the aerogel, or aerogels can be post-functionalized to target a specific application CNFs can be modified via chemical modification of hydroxyl groups, such as TEMPO-oxidation (Kim et al., 2021), carbox-ymethylation and phosphorylation (Patoary et al., 2021), or via chem-ical modifications via ring opening reactions, which typchem-ically breaks the C–C bonds of carbons at C2 and C3 position These reactions can further involve chemical grafting of polymers or single molecules to the CNF surface (Abushammala & Mao, 2019; Rol et al., 2019) Although these modifications have become relatively common, with acceptable yields, implementation of these reactions while maintaining dispersion stability can be challenging Specifically, it is difficult to avoid aggregation of the system or to properly remove excess reagents, which can subsequently inhibit aerogel formation Thus, it is often favorable to perform a post functionalization of the aerogels Generally, CNF-based aerogels can be modified via vapor- or liquid-based methods Commonly, silanes, organosilanes or other fluorine-containing chemicals are evaporated and allowed to diffuse through the aerogel (Liao et al., 2016; Yu et al.,

2021; Zhu et al., 2020) However, these chemical vapor deposition

* Corresponding author at: Department of Fiber and Polymer Technology, KTH Royal Institute of Technology, Teknikringen 56–58, SE-100 44 Stockholm, Sweden

E-mail addresses: zhaato@kth.se (Z Atoufi), mreid@kth.se (M.S Reid), perl5@kth.se (P.A Larsson), wagberg@kth.se (L Wågberg)

Contents lists available at ScienceDirect Carbohydrate Polymers journal homepage: www.elsevier.com/locate/carbpol

https://doi.org/10.1016/j.carbpol.2022.119098

Received 27 September 2021; Received in revised form 29 December 2021; Accepted 1 January 2022

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methods usually involve toxic and expensive chemicals, are diffusion

limited and can result in non-uniform modification Another method is

Cold plasma which is more environmentally friendly, but similarly

limited and require lengthy processing and high discharge energy

(Schroeter et al., 2021) As a result, it can be more effective to use liquid

modification methods, whereby the capillary forces uniformly wet the

aerogel surfaces Although these chemical grafting methods are usually

very efficient, they can require complex reactions and processing

con-ditions which are not favorable for large-scale production (Xu et al.,

2019) Therefore, there is a demand for an efficient and fast

modifica-tion technique which is applicable for cellulose aerogels

Molecular layer-by-layer (m-LBL) deposition is a unique technique

which allows for the deposition of ultra-thin layers onto a surface

through sequential covalent reactions The result is the formation of a

precise molecular-scale coating, essentially via surface oligomerization,

which cannot be achieved by bulk synthesis methods (Chan et al., 2012;

Johnson et al., 2012) With m-LBL, it is possible to precisely control the

surface chemistry, roughness and the thickness of the deposited film

(Chan et al., 2013) The presence of numerous hydroxyl groups on the

surface of CNF-based aerogels make them suitable substrates for m-LBL

modification However, CNF-based aerogels must be prepared such that

they are mechanically robust and can maintain their structure through

the modification process

CNF-based aerogels are typically prepared through freeze drying or

critical point drying of CNF dispersions (Mulyadi et al., 2016) However,

due to the hydrophilicity of CNFs, unmodified aerogels are generally not

wet-stable and disintegrate, (Kim et al., 2017) making them unsuitable

for m-LBL modification Additionally, scale-up of these aerogels is

challenging due to the high energy consumption of freeze drying and

critical point drying techniques One way to prepare wet-stable CNF-

based aerogel-like materials with scale-up possibility is the so-called

freeze-linking technique (Erlandsson et al., 2016), whereby aerogel-

like structures are prepared through molding and freezing of CNF

dispersion followed by solvent exchange and ambient drying During

freezing, ice crystal growth forces CNFs together to form a strong

micrometer thick interconnected network structure By solvent

exchanging to acetone capillary forces are significantly reduced such

that the aerogel-like structure is maintained during ambient drying

Although freeze-linked aerogel-like structures usually have larger pores

and lower specific surface area compared to conventional aerogels, the

fact that they can be prepared without using critical point drying or

freeze drying is indeed a huge advantage Additionally, by incorporating

calcium ions or using aldehyde-containing CNFs, the aerogel-like

structure can be physically or covalently crosslinked during freeze-

linking to obtain wet stability (Erlandsson et al., 2018; Françon et al.,

2020)

We hypothesized that m-LBL modification is an efficient method to

tune the surface properties and functionality of CNF-based aerogels In

this study, two types of wet-stable CNF-based aerogel-like structures

were prepared through a freeze-linking technique: i) hemiacetal

cross-linked aerogel-likes, where dialdehyde-containing CNFs are chemically

crosslinked through hemiacetal bonds formed between the individual

CNFs during freezing, and ii) calcium ion cross-linked aerogel-likes, in

which calcium ions physically crosslink the structure Both aerogel-likes

(hereafter called aerogel) were then modified through m-LBL deposition

of trimesoyl chloride (TMC) and m-xylylene diamine (MXD), resulting in

an ultrathin polyamide film covering all surfaces throughout the

aero-gels The chemical structure, atomic composition, thickness and

roughness of the deposited film was characterized and the effect of m-

LBL modification on morphology, wet and dry mechanical properties,

acid-base resistance, thermal degradation and surface properties of the

aerogels was investigated Finally, the modified aerogels were examined

for potential use as oil-water separators for water purification

2 Experimental section

2.1 Materials

Carboxymethylated CNFs with a total charge of 600 ± 50 ueq/g were produced according to a previously reported method (Wågberg et al.,

2008) and provided by RISE Bioeconomy AB in the form of 20 g/l aqueous gel Branched polyethylenimine (PEI) with the molecular weight of 25,000 Da, poly(allylamine hydrochloride) (PAH) with the molecular weight of 17,500 Da, molecular sieve beads (pore diameter of

3 Å and 4 Å, 8–12 mesh), trimesoyl chloride, m-xylylene diamine, oil red

O, toluene (ACS reagent, ≥99.5%), calcium chloride, and sodium hy-droxide were purchased from Sigma Aldrich Sodium metaperiodate (99%) was purchased from Acros Organic, Belgium Acetone was pur-chased from VWR International (Radnor, PA, USA)

Prior to use, water was carefully removed from acetone and toluene with the aid of the molecular sieves All other chemicals were used without further purification

2.2 Sample preparation 2.2.1 Synthesis of calcium ion crosslinked aerogels

CNF gels with a concentration of 7.5 g/l were mixed with CaCl2 using

an Ultra Turrax (IKA Werke GmbH & Co KG, Staufen, Germany) at

12000 rpm for 5 min Total concentration of CaCl2 in the CNF gel was 13.5 mM to achieve a 3:1 ratio of calcium ions to CNF charge groups The gels were then placed into cylindrical polystyrene molds and frozen

in a freezer (− 18 ◦C) overnight to ensure a complete freezing The frozen samples were then thawed and solvent exchanged in acetone followed

by ambient drying Calcium ion crosslinked aerogels are abbreviated as Ca-AG in the text

2.2.2 Synthesis of hemiacetal crosslinked aerogels

Hemiacetal crosslinked aerogels (HA-AG) were prepared according

to an earlier described method (Erlandsson et al., 2016) Briefly, dia-ldehyde CNFs were prepared by mixing a 7.5 g/l CNF gel with sodium metaperiodate to a concentration of 60 mM, using an Ultra Turrax disperser at 12000 rpm for 5 min The mixture was covered with aluminum foil to prevent exposure to light After 1 h of reaction, the obtained gel was quickly transferred to a mold and frozen (− 18 ◦C) overnight, thawed and solvent exchanged to acetone, dried under ambient conditions and stored for further use Before use, the aerogels were thoroughly rinsed with water until the conductivity of the washing water was below 5 μS/cm

2.2.3 Preparation of CNF dispersions

CNF dispersions were prepared according to an earlier described method (Erlandsson et al., 2018) A 20 g/l CNF gel was diluted to 2 g/l and homogenized with an Ultra Turrax at 12000 rpm for 10 min The dispersion was then ultrasonicated at 300 W for 10 min using an ul-trasonic probe (Sonics VCX 750, Newton, USA) followed by centrifu-gation at 4500 rpm for 1 h The stable CNF supernatant was collected and stored in the fridge for further use The dry content was obtained gravimetrically

2.2.4 Molecular layer-by-layer deposition on cellulose aerogels

CNF-based aerogels were modified by three cycles of m-LBL depo-sition of TMC and MXD molecules to form a thin polyamide film on the surface Each bilayer was deposited using a four-step procedure as shown schematically in Fig 1 First, aerogels were soaked in a solution

of 1 wt% TMC in toluene for 2 min to ensure that the reactants have penetrated the entire aerogel and reacted with the cellulose surface The aerogels were then soaked in toluene with being the solvent replaced every 5 min a total of three times The aerogels were then dried by vacuum filtration to remove excess toluene as to not dilute the reactants

in the next step The dried aerogels were then soaked in a 1 wt% solution

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Carbohydrate Polymers 282 (2022) 119098

of MXD, in toluene, for 2 min The MXD modified aerogel was then

soaked in acetone with the solvent being replaced every 5 min a total of

three times, followed by vacuum filtration These steps repeated three

times to achieve three bilayers on the surface of the aerogels

2.2.5 Preparation of CNF films

CNF films were prepared by vacuum filtration of 75 ml of 2 g/l CNF

dispersion through a 0.45 μm membrane (Durapore, Merck Millipore)

After filtration, the obtained wet film was dried for 15 min at 93 ◦C and

95 kPa using the dryer of a Rapid-K¨othen sheet former (PTI, Austria)

2.2.6 Preparation of CNF model surfaces

The formation of m-LBL layers inside the three-dimensional CNF-

based aerogel structures is difficult to study due to the thin nature of the

deposited film (<5 nm) and complex structure of the aerogels To

circumvent this problem, model CNF surfaces were prepared to

inves-tigate m-LBL film formation CNF model surfaces were prepared on

sil-icon oxide surfaces with a pre-adsorbed layer of cationic anchoring

polymer Specifically, silicon oxide surfaces (Addison Engineering, Inc.,

USA) were plasma cleaned for 3 min (Harrick PDC-002, Harrick

Scien-tific Corporation, Ithaca, USA) and activated in 10 wt% NaOH solution

Silicon oxide surfaces were immersed in 0.1 g/l PAH containing 10 mM

NaCl at pH 7 for 30 min followed by excessive rinsing with MilliQ water

CNFs were then adsorbed on the surface by dipping the silicon surfaces

in 0.1 g/l solution of CNF at pH 7 for 5 min followed by washing with

MilliQ water Subsequently, PEI was adsorbed on the surface by soaking

the silicone surfaces in 0.1 g/l aqueous pH 7 solution This process was

continued until five bilayers of PEI and CNFs were adsorbed onto the

surface, yielding a smooth, tightly packed cellulose surface

2.2.7 m-LBL deposition on CNF model surfaces and CNF films

To study the layer growth and changes to the surface roughness, CNF

model surfaces were modified with 5, 10, and 15 bilayers of m-LBL

deposition and scratched and imaged by atomic force microscopy (AFM) Solutions of 1 wt% TMC and MXD in toluene were prepared CNF model surfaces were soaked in TMC solution for 30 s followed by excessive washing with toluene The CNF surfaces were then soaked in MXD solution for 30 s, washed excessively with acetone followed by drying under a gentle flow of nitrogen gas These steps were repeated to achieve the desired number of bilayers The same procedure was used to adsorb TMC/MXD bilayers on the free standing CNF films

2.3 Analysis 2.3.1 Carbonyl content determination

Aldehyde content within HA-AGs was measured using a titration method described earlier (Larsson et al., 2008; Lopez Duran et al.,

2018) Specifically, hydroxylamine hydrochloride reacts with all avail-able aldehyde groups in the aerogel to release a stoichiometric amount

of protons, which are then titrated by hydroxyl ions HA-AGs were cut into approximately 80 mg pieces and added to 25 ml solutions con-taining 10 mM NaCl and pH adjusted to pH 4 An amount of 25 ml of 0.25 M hydroxylamine hydrochloride in 10 mM NaCl was then added to each aerogel mixture to initiate a reaction between aldehydes and hy-droxylamine After 2 h, the mixture was titrated with 0.1 M NaOH back

to pH 4 The aldehyde content of HA-AGs was calculated as the amount

of NaOH consumed per gram of sample Samples were tested in triplicate for each type of aerogel

2.3.2 Aerogels density and porosity measurements

Aerogels were prepared using cylindrical polystyrene molds The density of the aerogels was obtained by dividing their weight by their volume and their porosity was estimated according to:

porosity =

(

1 − ρ*

ρ s

)

Fig 1 a) Molecular layer-by-layer deposition of TMC and MXD on a CNF-based aerogel b) Schematic illustration of the formation of polyamide film by sequential

reaction of TMC and MXD monomers with the cellulose surfaces during the deposition The term lamellae in the figure refers to the internal walls of the aerogels that were formed during the preparation of the aerogels

Z Atoufi et al

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where ρ* is the calculated density of the aerogels and ρ is the pore wall

density (Lopez Duran et al., 2018) For neat cellulose aerogels, ρ was

estimated to be cellulose density (1500 kg⋅m− 3) while for modified

aerogels it was calculated according to the mass of deposited polyamide

layer:

ρ s=m c+m PA

mc

ρ c+mPA

ρ PA

(2) where mc, mPA, ρc, and ρPA are the initial mass of cellulose aerogel, mass

of deposited polyamide layer, density of cellulose and density of

poly-amide, respectively

2.3.3 Fourier transform infrared spectrometry

Fourier transform infrared spectrometry (FTIR) was performed

before and after m-LBL modification of the aerogels using a PerkinElmer

Spectrum 100 FTIR equipped with a Golden Gate attenuated total

reflection accessory (Specac Ltd., Kent, England) with a set resolution of

4 cm− 1 in the spectral region of 4000–600 cm− 1 Spectra were baseline

corrected and normalized by the PerkinElmer software at 1030 cm− 1, a

wavenumber corresponding to the C–O stretch band in the cellulose

backbone

2.3.4 Contact angle analysis

The water contact angle of a 3 μl droplet of ultra-pure water on the

CNF films before and after the deposition of three m-LBL layers was

measured under conditions of 25 ◦C and 50% relative humidity by a KSV

instrument CAM 200 equipped with a Basler A602f camera All

mea-surements were performed in triplicate

2.3.5 Mechanical properties

The mechanical properties of the aerogels were measured using an

Instron 5566 universal testing machine (Norwood, USA) equipped with

a 500 N load cell The aerogel samples were in cylindrical form with

average diameter of 28 mm and thickness of 8 mm Dry compressive

tests were performed for the aerogels conditioned at 50% RH and 23 ◦C

for 48 h, with a strain rate of 10%/min until they reached 90%

compression To determine the mechanical properties of wet aerogels,

samples were immersed in deionized water for 48 h prior to testing The

wet aerogels were then compressed to 80% compression, followed by

gradual removal of the force applied by again separating the clamps at a

rate of 10%/min The obtained mechanical data for each aerogel was

then normalized to its post-conditioned density Each type of aerogel

was tested in triplicate

2.3.6 Atomic force microscopy

CNF model films on silicon oxide substrates were imaged under

ambient conditions using a MultiMode 8 AFM in ScanAsyst mode

(Bruker, Santa Barbara, CA) Root-mean-squared (rms) roughness of the

surfaces was calculated over eight individual 2 × 2 μm2 areas The

thickness of the CNF films before and after m-LBL deposition was

determined via scratch test according to a previously established

method (Reid et al., 2016) Briefly, in contact mode (with a deflection

set point of approximately 1 V) an AFM cantilever was scanned over a 1

×1 μm2 area to detach CNFs from the surface The applied force was set

to be sufficient to detach the CNFs from the surface without damaging

underneath silica substrate (Reid et al., 2016) The scratched area was

then reimaged in tapping mode to obtain the cross-sectional profile

Images were analyzed using NanoScope Analysis software

2.3.7 Scanning electron microscopy

The microstructure of the aerogels was studied using an S-4800 field

emission scanning electron microscope (SEM; Hitachi, Tokyo, Japan)

Aerogels were frozen in liquid nitrogen and cut into thin rectangular

shapes and mounted on the sample holder using carbon tape To

mini-mize charging, samples were coated with a Pt–Pd alloy for 40 s using a

Cressington 208 HR sputter coater (Cressington Scientific Intruments, Watford, UK)

2.3.8 X-ray photoelectron spectroscopy

X-ray photoelectron spectroscopy (XPS) spectra were recorded using

a Kratos AXIS UltraDLD x-ray photoelectron spectrometer (Kratos Analytical, Manchester, UK) The aerogel samples were analyzed using a monochromatic Al x-ray source and the analysis area was approximately 0.7 × 0.3 mm2 Detailed spectra of each individual element was recor-ded and quantified in order to obtain the relative elemental composition

of the surface expressed in atomic %

2.3.9 Thermogravimetric analysis

Thermogravimetric analysis (TGA) of the aerogels was performed using a Mettler Toledo TGA/DSC 1 STARe System at a temperature range

of 30–700 ◦C and a heating rate of 10 ◦C/mins under constant nitrogen flow Specimens were conditioned at room temperature before mea-surement and a minimum of 3.5 mg was used for each meamea-surement

2.3.10 Absorption and reusability study

The oil absorption capacity of the aerogels was measured by immersing the aerogels in 20 ml of organic solvent for 30 s The aerogels were taken out and weighed after the superficial solvent was wiped off

by a filter paper The absorption capacity was calculated as the mass of oil absorbed per mass of dry aerogel prior to immersion Five replicates were used for each type of aerogel

To study the reusability of HA-AGs in absorbency applications, the absorbed solvent was removed from the aerogel, and collected, using vacuum filtration The aerogels were then dried followed by a repeated absorption test This absorption-removal cycle was repeated five times Four replicates were performed

To test the separation efficiency, multi-functional samples were assembled such that the center was constituted by m-LBL modified aerogel and the surrounding area by unmodified CNF-based aerogel, and vice versa Samples were prepared by punching the middle of the un-modified aerogels out and filling the created void with a piece of modified aerogel The multi-functional samples were then soaked in a stirred mixture of toluene (dyed with oil red) and water (dyed with brilliant blue)

3 Results and discussion

3.1 Principles of aerogel preparation and functionalization

The impact of m-LbL deposition on covalently and physically cross-linked CNF-based aerogels, prepared by the freeze-linking technique, was examined Covalently crosslinked aerogels (HA-AG) consisted of dialdehyde CNFs crosslinked through hemiacetal linkages formed in the aerogel lamellae during ice templating Crosslinking specifically occurred during the formation and growth of ice crystals where the CNFs are forced together to form strong interconnected pore walls that can withstand capillary pressures following solvent exchange and ambient drying (Erlandsson et al., 2018) The HA-AGs contained 1.2 ± 0.1 mmol⋅g− 1 aldehyde, corresponding to a degree of oxidation of approx-imately 10% of all glucose units of the cellulose in the fibrils The density and porosity of these aerogels was 13.9 kg⋅m− 3 and 99.1%, respectively The second group of aerogels (Ca-AG) consisted of CNFs physically crosslinked by calcium ions using the same freeze linking method The Ca-AGs had nearly the same low density and high porosity as the HA- AGs (14.3 kg⋅m− 3 and 99.0%)

The prepared aerogels were then modified with three bilayers of TMC and MXD After modification, both physically and covalently crosslinked aerogels yellowed in color (the color was more significant in HA-AG-3LBL) and became hydrophobic enough to float on water (Fig 2a,c) To assess the effect of m-LBL modification on the hydro-phobicity, water contact angle measurements were performed on free-

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Carbohydrate Polymers 282 (2022) 119098

standing CNF films The water contact angle of the unmodified CNF film

was 55◦, slightly higher than, but in the same range as several reported

values in literature (Aulin et al., 2009; Kang et al., 2017; Sethi et al.,

2019) Nonetheless, after three m-LBL deposited bilayers, the water

contact angle increased from 55◦to 77◦(Fig 2b) According to earlier

investigations the contact angle of interfacially polymerized PA thin

films from TMC and m-phenylenediamine is 79◦(Rajaeian et al., 2013)

Hence, a contact angle of 77◦indicates a good coverage of the surface

with a thin PA film after three m-LBL bilayers In addition to the

increased contact angle, modified HA-AGs and Ca-AGs showed an

in-crease in mass of 24.1% and 49.3% and a volume reduction of 21.5%

and 24.9% Thus, the final HA-AG-3LBL and Ca-AG-3LBL had a density

of 21.9 kg⋅m− 3 and 28 kg.m− 3 and porosity of 98.5% and 97.9%,

respectively Furthermore, no mass loss was observed after soaking the

modified aerogels in toluene for 1 week demonstrating that the

depos-ited layers are stable and don't dissolve or detach in the solvent FTIR

spectra of the modified aerogels show characteristic amide signals at

1540, 1610 and 1645 cm− 1, assigned to N–H bending, H-bonded C––O

and C––O stretching modes, respectively (Johnson et al., 2012; Reid

et al., 2019) (Fig 2d) However, the signal intensity was higher for Ca-

AG-3LBL, in agreement with the larger weight increase of the aerogels

It is worth mentioning that since the last molecular layer used in this

process was MXD, the surface of the aerogels was covered with a high

concentration of amine groups which can be utilized as a platform for

further chemical reactions or other applications requiring amine

func-tionality such as CO2 capturing (Jiang, Oguzlu, & Jiang, 2021; Zhu et al.,

2020) Moreover, by using TMC as the final layer or by utilizing other

types of monomer, the surface functionality can be tailored This indeed

makes m-LBL deposition a valuable and efficient method for controlling

surface functionality

3.2 Characterization of the molecular layers

To better characterize the build-up of the molecular layers on the CNF-based aerogels, CNF model surfaces were prepared and subjected to

5, 10 and 15 bilayers of m-LBL deposition AFM images clearly demonstrate the formation and growth of a smooth and uniform layer on the CNF surfaces Fig 3a,b shows that after deposition of five molecular bilayers, the CNF surface becomes smoother with the surface roughness decreasing from 3.2 to 1.8 nm (Table S1) Continuing m-LBL deposition

to 15 bilayers (Fig 3d), the deposited layer grew thicker making it difficult to clearly distinguish the supporting CNF surface The deposited film remained smooth and uniform with a roughness of 2.1 nm, lower than the roughness of the initial CNF surface To measure the thickness

of deposited molecular layers, scratch tests were performed for the CNF surfaces before and after 5, 10, and 15 cycles of m-LBL deposition Fig 3e,g displays the scratched CNF surfaces after 15 m-LBL cycles and the average cross sectional analysis of the film The scratched image shows that CNFs in the scratched areas are detached from the substrate and accumulate as ridges around the scratched area The total thickness

of the layer was measured as the height difference between the scratched substrate and the unaffected modified CNF surface The thickness of the deposited molecular layer was then measured as the thickness difference

of the CNF surface before and after m-LBL deposition

Fig 3f presents the thickness of the deposited film per cycle of m-LBL deposition Unlike m-LBL modification of nearly atomically flat surfaces (Chan, Lee, Chung, & Stafford, 2012; Johnson et al., 2012), the thickness growth of the deposited polyamide film on the CNF surfaces is not linear This non-linear growth is most probably due to 3D structure and the roughness of initial CNF surface During the m-LBL modification, TMC and MXD molecules react with the surface and gradually grow, filling the empty areas between the fibrils and decreasing the surface rough-ness With each successive layer the surface area ideally increases and thus more and more molecules deposited on the surface, in turn creating

Fig 2 a) Photograph of the CNF-based aerogels before and after three bilayers of m-LBL deposition b) Water contact angle with CNF films before and after three

bilayers of m-LBL deposition c) Photograph of Ca-AG (left) and Ca-AG-3LBL (right) in contact with water d) FTIR spectra of the aerogels before and after three m- LBL depositions

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a larger surface for further modification (Fig 3 h) Similar, non-linear

growth has been reported for more conventional LBL assembly of

polyelectrolyte films (Haynie et al., 2011) According to Fig 3f, the

thickness of the deposited polyamide film after three bilayers is

approximately 1 nm and thus the thickness of deposited film on the pore

wall of the HA-AG-3LBL and Ca-AG-3LBL is predicted to be in a similar

range

3.3 Characterization of the aerogels

The microstructure of the aerogels was investigated by SEM imaging

Fig 4 shows the microstructure of HA-AGs before and after three

bi-layers of m-LBL deposition No significant difference is observed in the

microstructure of HA-AGs following three bilayers of m-LBL deposition,

demonstrating that the deposited film is very thin, smooth and uniform

No sign of monomer aggregation or inhomogeneity was observed after m-LBL modification These results are in line with AFM measurements which showed that the thickness of the coated PA film after three bi-layers is approximately 1 nm and thus, no significant difference is noticeable in the SEM images

SEM images of Ca-AG before and after three m-LBL modification is shown in Fig 5 Comparing the microstructure of the Ca-AG before (Fig 5a,b) and after m-LBL deposition (Fig 5c-f) demonstrates that in contrast to the HA-AGs, modification of Ca-AGs has resulted in a somewhat inhomogeneous pattern In some areas, the deposited film is very thin and homogeneous (Fig 5c,d) while in some other parts TMC and MXD molecules are polymerized to form a thick and inhomogeneous

PA layer on the surface (Fig 5e,f) This potentially could be ascribed to the less accessible areas where extra monomers were not effectively washed away and polymerization has occurred on the surface This

Fig 3 a-d) AFM images of CNF surfaces with 0, 5, 10, and 15 bilayers of m-LBL deposition e) AFM image of a scratched CNF surface after 15 m-LBL cycles f)

Thickness of the deposited layers per cycle of m-LBL deposition g) Average cross-section-height analysis of the scratched surface d) Schematic view of the growth of CNF dimensions by m-LBL deposition leading to the decrease in surface roughness and nonlinear thickness growth

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Carbohydrate Polymers 282 (2022) 119098

could also possibly be the reason for the higher weight increase of Ca-AG

after m-LBL deposition

XPS was performed to measure the surface chemical composition of

the aerogels before and after m-LBL modification Atomic composition

of oxygen, carbon, and nitrogen indirectly reveal the extent of the

re-action of TMC and MXD molecules with the cellulose surface

Specif-ically, the atomic ratios can be used to determine linear or branched

growth of the deposited molecular layers (Chan et al., 2013) Scheme S1

shows the two possible extremes of a fully branched and a fully linear m-

LBL reaction If all the three acid chloride groups in each TMC molecule

react with an MXD molecule, a fully branched structure with a C/O ratio

of 8.3 and an O/N ratio of 0.8 is obtained At the other extreme, if each

TMC molecule reacts with only two other MXD molecules a linear

structure with a C/O ratio of 4.3 and an O/N ratio of 2 is obtained,

assuming that the unreacted acid chloride is converted to carboxylic

acid due to the humidity of ambient conditions Therein, by comparing

the XPS results of the aerogels with the theoretical calculations, the

chemical structure of the deposited molecular layer can be predicted

From Table 1 it can be seen that the C/O and O/N atomic ratios of the

HA-AG-3LBL aerogel are very similar to the theoretical values for the

fully branched 3-mLBL structure In comparison, the atomic ratios of the

Ca-AG-3LBL aerogel are closer to the linear 3-mLBL structure For Ca-

AG-3LBL the O/N ratio of 3.7 is much larger than that of theoretical

values for three linear growth bilayers, suggesting that the supporting

CNF layer is likely contributing to the detected signal This in turn

in-dicates that the reaction between TMC and MXD is not as complete as for

the HA-AG-3LBL aerogels The exact reason for this difference is not

known, but the Ca2+ions may hinder the reaction between the TMC and

MXD, at least for very thin layers A lower nitrogen content for the Ca-

AG-3LBL may seem contradictory to the FTIR and weight

measurements; however, the minor areas of TMC and MXD polymeri-zation observed in SEM helps to clarify this contradiction These areas of polymerization are expected to be the result of the reaction of unwashed excess molecules, which lead to a higher weight increase and more intense amide peaks in FTIR Since XPS is a surface sensitive technique with an analysis depth of 5–10 nm (Laine et al., 1994) the results from XPS will be less affected by, poor washing and larger polymer aggregates within the bulk of the aerogel As a result, a lower concentration of N is predicted to be due to less effective m-LBL reaction on Ca-AG surfaces

To have a better understanding of the structure of HA-AG-3LBL, which showed uniform layer deposition, high-resolution XPS C 1S spectra of the HA-AG, before and after three m-LBL modification, were collected and deconvoluted into five sub-peaks corresponding to the chemical shifts in the carbon signals due to the different functional groups (Fig S1) The atomic percent of carbon linked to different functional groups was calculated (Table 2)

Theoretically, deconvolution of C 1s spectra of pure cellulose shows two peak at 286.7 eV (C2) and 288.3 eV (C3) corresponding to the C–O

at alcohol and ether groups and O—C—O at acetal moieties, respectively (Khiari et al., 2017) Comparing the deconvolution results of HA-AG with theoretical values, a decrease in C2 atomic percent and an in-crease in C3 is observed due to the conversion of some alcohol groups to aldehydes during the oxidation of CNFs and formation of hemiacetals linkages during the freezing-induced crosslinking (Guigo et al., 2014) The presence of C1b peak is attributed to the C–H and C–C groups in the residual lignin and hemicelluloses associated with the CNFs (Johansson & Campbell, 2004; Khiari et al., 2017; Yao et al., 2017) and the C4 peak is attributed to the carboxylic groups of the CNFs, since we used fibers that were subjected to a carboxymethylation pre-treatment

to facilitate fibrillation to CNFs

Fig 4 Micrographs of a,b) HA-AG and c,d) HA-AG-3LBL at two different magnifications

Z Atoufi et al

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According to Fig S1 and Table 2, after deposition of three m-LBL

bilayers, a significant peak at C1 appeared This peak, which is

equiv-alent to 46.7 atomic percent, is attributed to the C––C groups present in

both TMC and MXD, demonstrating the high efficiency of m-LBL

reac-tion on HA-AG Moreover, the fact that the atomic amount of C4 carbon,

corresponding to carboxylic groups, is zero shows that all the acid

chloride groups in the TMC molecules have reacted with MXD and a

fully branched structure is obtained (Scheme 1) By comparing the

percentage of C1 and C2 carbon within the HA-AG-3LBL with the

theoretical data for three fully branched m-LBL bilayers, it can be

concluded that the amount of C2‑carbon is higher while the C1 carbon is

lower for HA-AG-3LBL This can be explained by the signals detected

from the supporting cellulose surface For example, since there is no

C––C group in cellulose, the intensity of C1 peak in the HA-AG-3LBL is

lower than the theoretical value On the other hand, the intensity of C2

peak is higher than the theoretical value due to the O-C-O and C––O signals coming from the supporting dialdehyde cellulose layer

3.4 Mechanical properties

The dry and wet mechanical properties of the aerogels before and after m-LBL deposition was evaluated by uniaxial compression test (Fig 6) Similar to the mechanical properties previously reported for the same type of aerogels (Luo et al., 2020; Wang, Li, et al., 2020), the compressive-stress–strain curve of all the aerogels exhibited three

deformation regions Specifically: i) a linear elastic region below 10% strain due to the elastic bending of lamellae, ii) a relatively flat stress plateau region (10% < strain < 60%) due to plastic deformation and failure of the lamellae, and iii) a densification region above 60% strain

where a dramatic increase in the stress was observed due to the overall

Fig 5 Microstructure of Ca-AG and Ca-AG-3LBL a,b) microstructure of Ca-AG c,d) Representative microstructure of Ca-AG-3LBL, showing neat features e,f)

Example of random, non-representative, inhomogeneous microstructure of Ca-AG-3LBL occurring at some positions in the modified aerogel

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Carbohydrate Polymers 282 (2022) 119098

densification of the structure after collapse of the pores, leading to an

increased number of contact points According to Table 3, the ultimate

strength and the compressive modulus of both aerogels in the dry state

has increased significantly after three cycles of m-LBL deposition

However, by normalizing the data with density, it was observed that the

specific mechanical properties did not change significantly after

modi-fication Comparing CNF films and interfacially polymerized polyamide

thin films, the specific strength and modulus of CNF films are

signifi-cantly higher in the dry state (Benítez & Walther, 2017; Roh et al.,

2002) Thus, the thin layer of polyamide on CNF-based aerogels is

ex-pected to either; i) reduce the specific mechanical properties of the

aerogel via the addition of a weaker thin film, or ii) increase the specific

mechanical properties by improving joint strength between the

indi-vidual CNFs as well as the larger lamellae The slightly increased specific

modulus and strength of HA-AG after three bilayers indicate that

improvement of the joint strength between the structural elements is

greater than the lower intrinsic mechanical properties of the polyamide

film This is in good agreement with the SEM images, whereby ultrathin

uniform polyamide layers were observed on the HA-AG-3LBL On the

other hand, the specific strength of Ca-AG reduced slightly after m-LBL

deposition suggesting that improvement of CNF joint strength was less

effective The SEM images show that in some parts of Ca-AG-3LBL thick

and inhomogeneous polymerized layers were deposited, which reduce

the specific compressive strength of the treated aerogels

To assess the mechanical properties in the wet state, the aerogels

were soaked in water for 48 h to ensure that both unmodified and

modified aerogels were sufficiently hydrated According to Table 3, the

wet mechanical properties were improved significantly after m-LBL

modification Comparing Ca-AG and Ca-AG-3LBL, the specific modulus

increased 2.6 times from 0.32 kPa⋅m3/kg to 0.84 kPa⋅m3/kg The same

trend was observed for HA-AGs where their specific modulus increased

2.5 times from 0.4 kPa⋅m3/kg to 1.0 kPa⋅m3/kg and specific ultimate

strength increased from 0.5 kPa⋅m3/kg to 1.0 kPa⋅m3/kg This

improvement can potentially be attributed to the chemical crosslinking

of the CNFs at the surface of lamellae following m-LBL deposition,

resulting in a stronger interconnected network structure Additionally, water is a well-known plasticizer for cellulose-based materials and thus coverage of the surface with a more hydrophobic polyamide film re-duces swelling and improves wet integrity While m-LBL modified aer-ogels show good improvement in the wet state, Fig 6b shows large hysteresis after m-LBL deposition indicating the mechanical failure of the aerogels This is potentially due to the rupture of the thin polyamide film at high compressive strain, which allows water to enter the un-derlying CNF network and weaken the pore walls

Fig 6c shows a comparison of the dry compressive modulus of HA- AG-3LBL and Ca-AG-3LBL as a function of density with relevant CNF- based aerogels reported in the literature Considering the density of the aerogel, m-LBL modified aerogels show higher compressive modulus compared to most chemically modified CNF, microfibrillated cellulose (MFC) and CNC-based aerogels Their modulus is also comparable with several CNF-based composites The fact that aerogels are weaker in comparison with 3D printed or the strongest direction in directionally freeze dried aerogels demonstrates the advantage of 3D printing and directional freezing in design of light-weight materials The main advantage of m-LBL modification on the mechanical properties can be seen in the wet state There are only a few studies in the literature clearly reporting the wet modulus of the light-weight cellulose-based structures (Fig 6d) Considering the low density of m-LBL modified aerogels pre-pared in this work, they have greater wet stiffness compre-pared to CNF, CNC, and CNF-alginate aerogels However, 3D printed light-weight cellulose structures still show superior wet properties

In addition to mechanical properties, the stability of aerogels under acidic and basic aqueous solutions (pH 0–13) was tested All the aerogels were stable in acidic and mild basic conditions (pH 0–8.5), showing no visual degradation during 1 week of incubation However, in basic conditions of above pH 10, the HA-AG disintegrated, while all the other aerogels were stable (Fig S2 a,b) This is due to the fact that hemiacetal linkages break at high pHs since the equilibrium shifts toward free aldehyde and alcohol groups (Erlandsson et al., 2018) Additionally, the stability of aerogels was tested at extremely harsh acidic environment (37% HCl solution) where the unmodified aerogels disintegrated within

2 min while the m-LBL modified aerogels were visually intact up to 5 h (Fig S3) This stability demonstrates that the molecular layers deposited

on the aerogel surfaces have covered and crosslinked the cellulose sur-faces and prevented the hydrolysis of the CNFs by HCl The acid/base resistance of the m-LBL modified aerogels make them promising can-didates for applications needing long term exposure to acid and alkalis The effect of m-LBL modification on thermal stability of the aerogels was tested by TGA and is shown in Fig S4 and discussed in detail in Supplementary Data Notably, while modified aerogels showed a decrease in the onset of degradation temperature they maintained significantly higher residual weight at 700 ◦C Strong interactions be-tween deposited layer and CNF, and the high thermal stability of poly-amides is potentially reason for the improved thermal stability of

modified aerogels at temperatures >350 ◦C

Table 1

Atomic composition analysis of aerogels before and after m-LBL modification by

XPS

3 LBL linear growth a 73.9 17.4 8.6 4.3 2.0

3 LBL branched

0.4 43.5 ±0.4 0 1.3 ±0.0 –

0.4 43.6 ±0.3 0 1.3 ±0.0 – Ca-AG-3LBL 72.2 ±

1.0 19.3 ±1.6 5.2 ± 1.5 3.7 ±0.4 3.7 ±1.3 HA-AG-3LBL 77.0 ±

0.7 10.6 ±1.9 10.4 ±0.4 7.3 ±1.3 1.0 ±0.2

aTheoretical calculation (assuming that unreacted acid chloride is turned to

carboxylic acid due to ambient humidity)

Table 2

Atomic percent of carbon in different functional groups calculated from deconvoluted high-resolution C 1 s spectra

C groups atomic percent and their corresponding binding energy (eV)

284.7 C– – C

C 1b 285.0 C–C, C—H

C 2 286.1–286.7 C–O, C—N

C 3 287.9–288.3 O—C—O, C– – O, O=C—N

C 4 289.3 O—C=O

aTheoretical calculation

Z Atoufi et al

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3.5 Oil absorption properties

To assess the applicability of the aerogels in applications such as

water purification, the absorption capacity of the aerogels for six

different organic solvents (toluene, hexane, hexadecane, octane, xylene,

and decane) was investigated Fig 7a shows that the maximum

ab-sorption capacity differs with each organic solvent Generally,

absorp-tion capacity depends on both the characteristics of the aerogel, such as

density, porosity, and surface properties, as well as the characteristics of the solvent including density, hydrophobicity, molecular dimension, and surface tension (Li et al., 2014) Fig 7b demonstrates that the ab-sorption capacity of m-LBL aerogels is largely dependent on the density

of the solvent with hexane, which has the lowest density, absorbing the least and xylene and toluene, which have the highest density, absorbing the most

HA-AG-3LBL showed higher absorption capacity (25–36 g/g)

Fig 6 Compressive stress–strain curve of HA-AG and Ca-AG before and after three bilayers of m-LBL deposition; tested in a) dry and b) wet state c) A summary of

dry compressive modulus vs density of the modified aerogels in the present work ( ), and earlier investigations comprising MFC or CNF aerogels/foams ( ) (Buchtov´a et al., 2019; Dilamian & Noroozi, 2021; Gonz´alez-Ugarte et al., 2020; Li et al., 2017; Mariano et al., 2021; Verdolotti et al., 2019; Zhang et al., 2019), directionally freeze-dried pure and hybrid CNF aerogels parallel to the freezing direction ( ) (Chen et al., 2016; Wu et al., 2020; Zhang et al., 2020; Zhang, Wang,

et al., 2020), 3D printed CNF aerogels ( ) (Jiang, Oguzlu, & Jiang, 2021; Li et al., 2018), CNF composite aerogels ( ) (Françon et al., 2020; Gonz´alez-Ugarte et al.,

2020; Khlebnikov et al., 2020; Verdolotti et al., 2019; Wang et al., 2019; Wang et al., 2020; Wang, Li, et al., 2020; Zhang et al., 2016; Zhou et al., 2019), and CNC- based aerogels ( ) (Gong et al., 2019; Li et al., 2019) d) A Summary of the wet compressive modulus vs density of the modified aerogels of this work, MFC or CNF aerogels/foams ( ) (Mariano et al., 2021; Verdolotti et al., 2019), 3D printed CNF aerogels ( ) (Jiang, Kong, et al., 2021; Li et al., 2018), CNC based aerogels ( ) (Li

et al., 2019), cellulose fiber based aerogels ( ) (Lopez Duran et al., 2018), and CNF-alginate aerogels ( ) (Françon et al., 2020)

Table 3

Mechanical properties of aerogels in the dry and the wet state

Aerogel

type Dry compressive properties Ultimate Wet compressive properties

strength (kPa) Elastic modulus (kPa) Specific ultimate

strength (kPa⋅m 3 /kg)

Specific modulus (kPa⋅m 3 /kg) Ultimate strength (kPa) Elastic modulus (kPa) Specific ultimate strength (kPa⋅m 3 /kg) Specific Modulus (kPa⋅m 3 /kg)

Ca-AG 248 ± 24 118 ± 14 17.4 ± 0.7 8.3 ± 0.3 5.3 ± 0.7 4.2 ± 0.6 0.41 ± 0.06 0.32 ± 0.03 HA-AG 268 ± 58 131 ± 18 19.3 ± 1.7 9.6 ± 1.1 5.0 ± 0.9 4.2 ± 0.5 0.47 ± 0.1 0.40 ± 0.05 Ca-AG-

3LBL 465 ± 23 258 ± 58 16.5 ± 0.9 9.2 ± 1.9 17.5 ± 0.6 21.1 ± 2.9 0.7 ± 0.03 0.84 ± 0.12 HA-AG-

3LBL 497 ± 56 229 ± 13 22.5 ± 1.9 10.4 ± 0.3 20.0 ± 1.6 20.0 ± 1.1 1.0 ± 0.1 1.00 ± 0.10

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