779 improved design of oncoretroviral vectors for the delivery of HIV 1 TAT and rev RNA decoys

779 Improved Design of Oncoretroviral Vectors for the Delivery of HIV 1 TAT and Rev RNA Decoys Molecular Therapy Vol 5, No 5, May 2002, Part 2 of 2 Parts Copyright © The American Society of Gene Thera[.]

Molecular Therapy Vol 5, No 5, May 2002, Part 2 of 2 Parts Copyright © The American Society of Gene Therapy S254

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777 Internalization and Recycling of APJ, an HIV-1

Co-Receptor

Receptor, in T , in T , in Transfected Cells and Human Neurons ransfected Cells and Human Neurons

R J Pomerantz, 1 X Fan, 2 M Mukhtar, 1 G C DuBois, 2 N Zhou 1

1 Dorrance H Hamilton Laboratories, Center for Human Virology,

Division of Infectious Diseases, Department of Medicine,

Jefferson Medical College; 2 Kimmel Cancer Center, Thomas

Jefferson University, Philadelphia, PA, USA.

778 Engraftment and Development of HGTV43-T

Transduced CD34 ransduced CD34 + PBSC in HIV PBSC in HIV-1 Seropositive -1 Seropositive Individuals

Dakai Liu, 1 Marcus A Conant, 2 Morton J Cowan, 2 Jeffrey Laurence, 3 Christopher Eden, 2 Elizabeth Dunn, 2 Barbara E Thalenfeld, 1 Dean L Engelhardt 1

1 Enzo Therapeutics, Inc., Farmingdale, NY, United States;

2 University of California, San Francisco, San Francisco, CA, United States; 3 New York Presbyterian-Cornell Medical Center, New York, NY, United States.

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779 Improved Design of Oncoretroviral V

779 Improved Design of Oncoretroviral Vectors for ectors for the Delivery of HIV

the Delivery of HIV-1 T -1 T -1 TA A AT and Rev RNA T and Rev RNA T and Rev RNA Decoys Decoys

Stephen E Braun, 1 Fay E Wong, 1 Lorrin Lee, 1 Julianna Lisziewicz, 2 R Paul Johnson 1

1 Div of Immunology, NERPRC, Harvard Medical School, Southborough, MA, United States; 2 Research Institute for Genetic and Human Therapy, Washington, DC, United States.

Molecular Therapy Vol 5, No 5, May 2002, Part 2 of 2 Parts

Vector SD/SA Promoters Inhibitor Titer % Transient % Inhibition b Vector

(IU/ml) Inhibition a in Clones Stability Anti-Tat + MLV & 25 TAR/ 1 x 10 5 78 18 2/8

internal HIV AS Tat

Anti-HIV + MLV & 5TAR 1 x 10 5 65 0 1/8

internal HIV 3RRE (x3)

MMP LTR + MPSV & 5TAR 5.5 x 10 5 55 84 9/9

5T3R internal HIV 3RRE

MMP Ψ 2 - MPSV & 5TAR 5.8 x 10 5 58 44 11/11

LTR 5T3R internal HIV 3RRE

MMP 5T3R + MPSV only 5TAR 6.8 x 10 5 81 0 8/8

3RRE MMP Ψ 2 - MPSV only 5TAR 0.4 x 10 5 89 48 9/9





780 Inhibition of HIV-1 Reactivation by SV40 Mediated

Gene T

Gene Transfer of Catalase ransfer of Catalase

Francisco J Branco, David S Strayer.

1 Pathology, Thomas Jefferson University, Philadelphia,

Pennsylvania, United States.

781 Inhibiting HIV in Primary Lymphocyte Cultures Using Combinations of T

Using Combinations of Transgenes Delivered by ransgenes Delivered by Recombinant SV40 V

Recombinant SV40 Vectors ectors

David S Strayer, Carmen N Nichols, Francisco Branco.

779 Improved Design of Oncoretroviral V

779 Improved Design of Oncoretroviral Vectors for ectors for the Delivery of HIV< /b>

the Delivery of HIV- 1 T -1 T -1 TA... and Rev RNA T and Rev RNA T and Rev RNA Decoys Decoys

Stephen E Braun, Fay E Wong, Lorrin Lee, Julianna Lisziewicz, R Paul Johnson 1< /small>

1< /small> Div of. .. Stability Anti -Tat + MLV & 25 TAR/ x 10 78 18 2/8

internal HIV AS Tat< /small>

Anti -HIV + MLV & 5TAR x 10 65 1/ 8

internal HIV 3RRE (x3)