757 Delivery of Glucuronidase in the Adult Mouse Brain by Axonal Transport Results in the Reversal of Storage Lesions in Regions Distal to the Transduction Site Molecular Therapy Vol 5, No 5, May 2002[.]
Trang 1Molecular Therapy Vol 5, No 5, May 2002, Part 2 of 2 Parts Copyright © The American Society of Gene Therapy
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755 Human Blue Cone Opsin Promoter Delivered by
an
an AA AA AAV V V V V Vector Drives the Expression of a GFP ector Drives the Expression of a GFP ector Drives the Expression of a GFP Reporter Reporter
Gene Predominantly in Rat Cone Photoreceptors
Lyudmyla G Glushakova, Qiuhong Li, Adrian M Timmers, Thomas
Doyle, Vince Chiodo, William W Hauswirth.
1 Department of Ophthalmology, University of Florida, Gainesville,
Florida, United States; 2 Powell Gene Therapy Center, University
of Florida, Gainesville, Florida, United States.
756 HSV
756 HSV-1 -1 -1 Amplicon V Amplicon V Amplicon Vector-Mediated Expression of ector-Mediated Expression of
A
ATM cDNA TM cDNA TM cDNA and Correction of the and Correction of the and Correction of the Ataxia-T Ataxia-T Ataxia-Telangiectasia elangiectasia
Cellular Phenotype
Maria L Cortes, 1 Cristopher Bakkenist, 2 Michael V Di Maria, 1
Michael B Kastan, 2 Xandra O Breakefield 1
1 Molecular Neurogenetics Unit, Department of Neurology,
Massachusetts General Hospital, Boston, MA; 2 St Jude
Children ′s Research Hospital, Memphis, TN.
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8"898 ? "
8"898
757 Delivery of -Glucuronidase in the Adult Mouse Brain by
Brain by Axonal T Axonal T Axonal Transport Results in the Reversal of ransport Results in the Reversal of Storage Lesions in Regions Distal to the T
Storage Lesions in Regions Distal to the Transduction ransduction Site
Marco A Passini, 1 Edward B Lee, 1 Greg G Heuer, 1 Aracelis C Polesky, 1 John H Wolfe 1
1 Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, and Division of Neurology, Children ′s
Hospital of Philadelphia, Philadelphia, PA, United States.
Trang 2Molecular Therapy Vol 5, No 5, May 2002, Part 2 of 2 Parts
758 Several Hours Post-Ischemic Administration of
Sendai V
Sendai Virus V irus V irus Vectors Carrying Neurotrophic Factor ectors Carrying Neurotrophic Factor
Genes Prevent the Delayed Neuronal Death in Gerbils
Masayuki Shirakura, 1,2 Makoto Inoue, 1 Masayuki Fukumura, 1 Satoshi
Fujikawa, 1 Shintaro Komaba, 1 Kentaro Washizawa, 2 Takeo
Yamamoto, 1 Mitsuyo Maeda, 3 Kazuhiko Watabe, 4 Yasuhiro
Yoshikawa, 2 Mamoru Hasegawa 1
1 DNAVEC Research Inc., Ibaraki, Japan; 2 Department of
Biomedical Science, Graduate School of Agricultural and Life
Sciences, The University of Tokyo, Tokyo, Japan; 3 First
Department of Anatomy, Osaka City University Medical School,
Osaka, Japan; 4 Department of Molecular Neuropathology, Tokyo
Metropolitan Institute for Neuroscience, Tokyo, Japan.
$*? -&389 B
759 CB001, a Double-Mutant E1A/E1B Adenovirus,
Shows Anti-Cancer Effect in Experimental Human
Gliomas
Hong Jiang, 1 Cristina Balaguer, 2 Ramon Alemany, 2 Michael
Lemoine, 1 Candelaria Gomez-Manzano, 1 Charles Conrad, 1
Frederick F Lang, 3 Asadullah Khan, 3 W K A Yung, 1 Juan Fueyo 1
1 Neuro-Oncology, UT MD Anderson Cancer Center, Houston, TX,
United States; 2 Human Gene Therapy, University of Alabama,
Birmingham, AL, United States; 3 Neurosurgery, UT MD Anderson
Cancer Center, Houston, TX, United States.
760 Conditional Expression of T
760 Conditional Expression of Tumor Necrosis umor Necrosis Factor-Alpha in the Substantia Nigra of Adult Knock-in Mice Using
Mice Using Adenoviral V Adenoviral V Adenoviral Vectors and the CRE/loxP ectors and the CRE/loxP ectors and the CRE/loxP System System
Nelson Di Paolo, 1 Annette Schöeneberg, 2 Amaicha Depino, 1 Bernd Kirchherr, 2 Klaus Pfinzenmaier, 2 Osvaldo Podhajcer, 1 Ulrich Eisel, 2 Fernando Pitossi 1
1 Institute for Biochemical Research, University of Buenos Aires, Buenos Aires, Argentina; 2 Institut fur Zellbiologie und
Immunologie, Stuttgart, Baden-Wurttemberg, Germany.