312 enhanced therapeutic effect of mRTVP 1 gene therapy in combination with irradiation for prostate cancer

312 Enhanced Therapeutic Effect of mRTVP 1 Gene Therapy in Combination with Irradiation for Prostate Cancer Molecular Therapy Vol 5, No 5, May 2002, Part 2 of 2 Parts Copyright © The American Society[.]

Molecular Therapy Vol 5, No 5, May 2002, Part 2 of 2 Parts

VIRAL VECTORS ECTORS IN IN IMMUNOTHERAPY I

309 Oncolytically Enhanced Selectively Replicating

Adenovirus for Systemic Application

William Luckett, 1 Yi Gao, 1 Michael Karr, 1 Jing Gong, 1 Marilyn

Lemmon, 1 Rodney Prell, 1 Sylvie Laquerre 1

1 Virology, Onyx Pharmaceuticals, Richmond, CA, United States.

310 A Novel Oncolytic Adenovirus Encoding an IL-6/

sIL-6R Fusion Protein

Jonathan H Axelrod, 1 Stefan Rose-John, 2 Eithan Galun 1

1 The Goldyne Savad Gene Therapy Institute, Hadassah Medical

Organization, Jerusalem, Israel; 2 Institut fur Biochemie,

Christian-Albrechts-Universitat zu Kiel, Kiel, Germany.

" / ->8' J

"

"

31

311 In V 1 In V 1 In Vivo ivo ivo Anti-T Anti-T Anti-Tumor umor umor Activity of Oncolytic Activity of Oncolytic Adenoviruses That Express GM-CSF in Xenograft T Adenoviruses That Express GM-CSF in Xenograft Tumor umor Models

J Andrew Bristol, 1 Hong Ji, 1 Mervat Mina, 1 Mingzhu Zhu, 1 Suzanne Forry-Schaudies, 1 David Ennist 1

1 Genetic Therapy, Inc., A Novartis Company, Gaithersburg, MD, United States.

312 Enhanced Therapeutic Effect of mRTVP-1 Gene Therapy in Combination with Irradiation for Prostate Cancer

Takefumi Satoh, 1 Maria T Vlachaki, 2 Xiaohong Zhu, 2 Nobuyuki Kusaka, 1 Takashi Saika, 1 Terry L Timme, 1 Guang Yang, 1 Vladimir B Mouraviev, 1 Jianxiang Wang, 1 Bin Teh, 2 Brian Butler, 2 Timothy C Thompson 1,2,3

1 Scott Department of Urology; 2 Department of Radiology;

3 Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas, United States.

Molecular Therapy Vol 5, No 5, May 2002, Part 2 of 2 Parts Copyright © The American Society of Gene Therapy

S104

VIRAL VECTORS ECTORS IN IN IMMUNOTHERAPY I

6

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313 Evaluation of Recombinant Parvovirus H1

Expressing Interleukin-2 and Monocyte Chemotactic

Protein 1 in Gene Therapy of an Experimental Pancreatic

Cancer

Amor Hajri, Severine Wack, Christiane Dinsart, Juan Cornelis, Jean

Rommelaere, Marc Aprahamian.

314 The Epstein-Barr Virus (EBV)/Lipoplex-Mediated T

Transfection of Interleukin (IL)-12 and IL-18 Genes ransfection of Interleukin (IL)-12 and IL-18 Genes Augments T Helper 1 (TH1) Immune Responses and Therapeutic

Therapeutic Anti-Melanoma Effects of Anti-Melanoma Effects of Anti-Melanoma Effects of Autologous T Autologous T Autologous Tumor umor V

Vaccine accine

Hidetsugu Asada, 1 Tsunao Kishida, 1 Etsuko Satoh, 1 Hideyo Hirai, 1

Jiro Imanishi, 1 Osam Mazda 1

1 Microbiology, Kyoto Prefectural University of Medicine, Kyoto, Kyoto, Japan.

&

315 Antibody Induced Activation Has an Important Role to Play in Retroviral T

Role to Play in Retroviral Transduction ransduction

Ryan D Guest, 1 David E Gilham, 1 Natalia Kirillova, 1 Joely Irlam, 1

Allison O ′Neil, 1 Robert E Hawkins 1

1 CRC Dept of Medical Oncology, Paterson Institute of Cancer Research, Manchester, Greater Manchester, United Kingdom.