cover picture conformational dynamics of dna g quadruplex in solution studied by kinetic capillary electrophoresis coupled on line with mass spectrometry chemistryopen 2 2014

Berezovski N-Aryl Isoleucine Derivatives M... Mironov, Victor Okhonin, Nasrin Khan, Christopher M.. Berezovski* The cover picture shows two-dimensional separation of unfolded green and f

A Journal of

Open 2014 · 37 – 75 · Online ISSN 2191-1363 · Vol 3 · No 2 · April 2014

Full Papers:

Conformational Dynamics of DNA G-Quadruplexes

(M V Berezovski)

N-Aryl Isoleucine Derivatives

(M Larhed)

Cover Picture

Gleb G Mironov, Victor Okhonin, Nasrin Khan,

Christopher M Clouthier, and Maxim V Berezovski*

The cover picture shows two-dimensional separation of unfolded (green) and folded (red) forms of G-quadruplex DNA The first dimension is kinetic capillary electrophoresis (KCE) separation of unfolded and folded DNA with different potassium ion concentra-tions in solution The second dimension is ion mobility mass spectrometry separation of DNA conformers in the gas phase The picture further shows DNA folding into a com-pact G-quadruplex structure, which is mediated by potassium ions For more details, see the Full Paper by Maxim V Berezovski and co-workers, on p 58 ff