Ultrasound-switchable fluorescence for deep-tissue high-resolution imaging resolution imaging Dr.. Baohong Yuan received his PhD degree in Biomedical Engineering from University of Conne
Trang 1Ultrasound-switchable fluorescence for deep-tissue high-resolution imaging resolution imaging
Dr Baohong Yuan Department of Bioengineering, University of Texas at Arlington,
Friday, April 18, 2014 LECTURE: 9:00 AM - 10:00 AM
ENGINEERING CENTER
ROOM EC 1112
10555 WEST FLAGLER STREET
MIAMI, FL 33174
Biography: Dr Baohong Yuan received his PhD degree in Biomedical Engineering from University of Connecticut in 2006, and completed his post-doctoral training in Columbia University in 2007 As an as-sistant professor, he worked in Catholic University of America (CUA) from 2007 to 2010 Since 2010, he joined the bioengineering department at University of Texas at Arlington (UTA) His main research inter-est is to develop ultrasound-mediated fluorescence technology for cancer imaging As a PI, he has been awarded ~2 million dollars from Federal and State funding agencies, including NSF, NIH, DOD and CPRIT He has published 46 peer-reviewed journal papers, numerous conference papers/presentations, and several U.S patents He has served as an editor or editorial board member for Journal of Biomedical Op-tics, International Journal of OpOp-tics, Technology in Cancer Research and Treatment, and Austin Journal of Biomedical Engineering His major awards include NSF CAREER award, Outstanding Early Career Award (UTA), Kaman Award for Excellence in Research (CUA), and Burns Faculty Fellow (CUA)
Abstract: Fluorescence imaging in deep tissue with high spatial resolution is highly desirable because it can provide details about tissue’s structural, functional, and molecular information Unfortunately, current fluorescence imaging techniques are limited either in penetration depth (microscopy) or spatial resolution (diffuse light based imaging) as a result of strong light scattering in deep tissue To overcome this limita-tion, we developed an ultrasound-switchable fluorescence (USF) imaging technique whereby ultrasound was used to switch on/off the emission of fluorophores We synthesized and characterized unique USF con-trast agents The excellent switching properties of these agents, combined with the sensitive USF imaging system developed in this study, enabled us to image fluorescent targets in deep tissue with spatial resolu-tion beyond the acoustic diffracresolu-tion limit
Biomedical Engineering Wallace H Coulter Foundation
Lecture Series
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