EVALUATION OF THE ACUTE CUTANEOUS TOLERANCE OF A COSMETIC PRODUCT ON ADULT SUBJECTS: SINGLE PATCH TEST

EVALUATION, IN VIVO SUR L’HOMME, APRM03 F 020 V2 EN Report V1 0 July 16, 2021 DERMSCAN ASIA Co , Ltd 330046 47 29th Floor, Tower A Elephant Tower, Phaholyothin Road, Chomphon, Chatujak Bangkok 10900.cneAid Spot Gel AntiAcne (formula reference: INVTRT02) Study coordination: Dermscan Project Manager Preamrudee SANGTET: psadermscanasia.com Project Manager Assistant Pimrumpa VICHITNARK: pvidermscanasia.com Investigator (Dermatologist) Dr. Sujittra SOMBUNTHAM

APRM03-F-020_V2_EN Report_V1.0_July 16, 2021

DERMSCAN ASIA Co., Ltd

3300/46-47 29th Floor, Tower A

Elephant Tower, Phaholyothin Road,

Chomphon, Chatujak

Bangkok 10900

THAILAND

Tel + 66 2 937 4377

www.dermscanasia.com

iNova Pharmaceuticals Singapore Pte Ltd

10 Eunos Road 8, #08-02 North Lobby, Singapore Post Centre (North Lobby), 408600 SINGAPORE

Bangkok, July 16, 2021

Study Report # DA21A190 (version 1.0)

Related to quote# DA21A190

EVALUATION OF THE ACUTE CUTANEOUS TOLERANCE OF A COSMETIC PRODUCT

ON ADULT SUBJECTS:

SINGLE PATCH TEST

Acne-Aid Spot Gel Anti-Acne (formula reference: INV-TRT-02)

Study coordination:

Dermscan Project Manager

Preamrudee SANGTET: psa@dermscanasia.com

Project Manager Assistant

Pimrumpa VICHITNARK: pvi@dermscanasia.com

Investigator (Dermatologist)

Dr Sujittra SOMBUNTHAM

Dermscan Asia is certified ISO 9001 : 2015

including 13 pages

iNova Pharmaceuticals

Singapore Pte Ltd Acne-Aid Spot Gel Anti-Acne (formula reference: INV-TRT-02) DA21A190 3/13

SUMMARY OF THE STUDY REPORT # DA21A190

EVALUATION OF THE ACUTE CUTANEOUS TOLERANCE OF A COSMETIC PRODUCT ON ADULT SUBJECTS:

SINGLE PATCH TEST Objective To determine the acute irritating potential of a cosmetic product after single application under patch-test Methodology Monocentric and simple blind study

Kinetics

Product

Reference: Form: Storage temperature:

Acne-Aid Spot Gel Anti- Acne (formula reference:

INV-TRT-02) Translucent white gel

Room temperature

(Thailand Climate), (Dark place)

Studied Population

Main inclusion criteria Average age: Number of subjects analysed:

Age > 18 years old

Conclusion: Non irritating

D0 D2 t30min D2 t24h D3

Collection of the subject's informed consent ●

Verification of inclusion and non-inclusion criteria ●