GENE THERAPY APPLICATIONS docx
GENE THERAPY APPLICATIONS docx
... transplantation therapy. The ideal stem Gene Therapy Applications 26 Therapy, 2003). Progress in the field of gene therapy has been limited by safety concerns related to delivery vectors. Genetically ... R., J. Tongers, et al. (2009). Human studies of angiogenic gene therapy. Circ Res, Vol.105, No.8,(Oct 9), pp.724-736. Gene Therapy Applications 40 Fig. 2....
Ngày tải lên: 28/06/2014, 05:20
Gene Therapy - Tools and Potential Applications by Francisco Martin Molina Contributors ppt
... rapidly to background level by day 7 (figure 1a). When Gene Therapy - Tools and Potential Applications3 8 Gene types trasnferred in gene therapy clinical trials Adhesion molecule Antigen Antisense Cell ... cine Others Unknow n Figure 2. Gene types transferred in gene therapy clinical trials (adapted from http://www.wiley.co.k/genmed/clinical). Vectors used for gene therapy...
Ngày tải lên: 17/03/2014, 21:20
Chapter 065. Gene Therapy in Clinical Medicine (Part 3) docx
... of VEGF. Gene Therapy for Cancer The majority of clinical gene transfer experience has been in subjects with cancer (Fig. 65-1). As a general rule, a feature that distinguishes gene therapies ... Cancer gene therapies can be divided into local and systemic approaches (Table 65-2). Some of the earliest cancer gene therapy trials focused on local delivery of a prodrug or a su...
Ngày tải lên: 07/07/2014, 01:20
Báo cáo y học: " In silico modeling indicates the development of HIV-1 resistance to multiple shRNA gene therapy differs to standard antiretroviral therapy" docx
... C46) [49-51]. Conclusions In summary, resistance to gene therapy appears to differ from that for antiretroviral therapy. Although HSC gene therapy aims to establish a large protected population ... containing the therapeutic gene( s). It will likely be contained within a minority of these cells. Hence gene therapy provides a very different scenario to systemic antiretroviral th...
Ngày tải lên: 13/08/2014, 01:20
Báo cáo y học: " Derivation of normal macrophages from human embryonic stem (hES) cells for applications in HIV gene therapy" pps
... Cell-based Gene Therapy for HIV/AIDS. Anticancer Res 2003, 23:1997-2005. 14. Michienzi A, Castanotto D, Lee N, Li S, Zaia JA, Rossi JJ: RNA-medi- ated inhibition of HIV in a gene therapy setting. ... Thus, CD34 progenitor cells are an essential ingredient for HIV gene therapy. In view of the need for CD34 cells for HIV gene therapy as well as for other hematopoietic disorders,...
Ngày tải lên: 13/08/2014, 09:21
Báo cáo y học: "Comparison of osteogenic potentials of human rat BMP4 and BMP6 gene therapy using [E1-] and [E1-,E2b-] adenoviral vectors"
... E2b genes and the use of homologous (rat) BMP genes do not improve the osteogenic potential of direct BMP adenovirus vector gene therapy, the results of this study indicate that BMP gene therapy ... vector and to its transgene. J Immunol 1997; 159:685-93. 43. Varady P, Li JZ, Cunningham M, et al. Morphologic analysis of BMP-9 gene therapy- induced osteogenesis. Hum Gene Ther...
Ngày tải lên: 31/10/2012, 17:08
Báo cáo y học: "Gene Therapy: The Potential Applicability of Gene Transfer Technology to the Human Germline"
... to human germline gene therapy. 2. Criteria for Assessing Applicability to Human Germline Gene Therapy An ideal gene transfer system in the context of human germline gene therapy would have ... important advances in gene transfer technology. K K e e y y w w o o r r d d s s gene targeting; gene therapy; genetic modification; pronuclear microinjection; sperm-medi...
Ngày tải lên: 03/11/2012, 10:01
sermina lieu phap gen human gene therapy
... Simplex. nguyenthanhloi_2@yahoo.com 18 TRƯỜNG ĐH TÂY NGUYÊN KHOA KHTN & CN LIỆU PHÁP GEN (Human Gene Therapy) GVHD: Võ Thị Phương Khanh SVTH: Nguyễn Thành Lợi Hồ Thị Lan Anh Nguyễn Thị Trang nguyenthanhloi_2@yahoo.com ... nhằm tạo ra thế hệ sau bình thường. nguyenthanhloi_2@yahoo.com 6 Sử dụng các gen tự sát (Suicide gene) và gen độc tố đưa vào tế bào mới bị xâm nhiễm HIV cũng...
Ngày tải lên: 06/09/2013, 22:49