... interaction of ligands with cell surface receptors at 37 °C is a function not only of the rate constants of association and dissociation, but also of the endocytic rate constant, and measurements of these ... courses and effects of unlabeled ligands and low pH on the dissociation rates of [ 125 I]TC-PCSK9 (A) and [ 125 I]TC-PCSK9-D374Y (B) from HepG2 cells. Binding to...
Ngày tải lên: 14/02/2014, 14:20
... representations of meaning in a language. This correspondence is basically made up of a set of texts (T), a set of representations (S), and a relation between the two R(T,S), defined in terms of relations ... Analysis and synthesis can be considered to be two different ways of interpreting a single concept, this concept being a correspondence between the set of all...
Ngày tải lên: 18/03/2014, 02:20
Báo cáo y học: "Translational Medicine and Reliability of Single-Nucleotide Polymorphism Studies: Can We Believe in SNP Reports or Not"
... trials: authors’ name, year of publication, country of origin, type of cancer, sample size, number of polymorphisms tested and results of the study. Studies were divided into two categories ... Skovlund E, Nesland JM, Borresen-Dale AL. Single tube multiplex polymerase chain reaction genotype analysis of GSTM1, GSTT1 and GSTP1: relation of genotypes to TP53 tumor status...
Ngày tải lên: 25/10/2012, 10:51
Báo cáo y học: "Refractive Status and Prevalence of Refractive Errors in Suburban School-age Children"
... adhered to the provisions of the Declaration of Hel- sinki for research. The Bureau of Education and Bu- reau of Health in Yongchuan District approved the implementation of this study. Eye Examination ... influence on the prevalence of hyperopia and myopia: as age increased, the prevalence of hyperopia markedly decreased, and that of myopia significantly increased....
Ngày tải lên: 25/10/2012, 11:40
Báo cáo y học: "omparative Efficacy and Tolerability of 5-Loxin® and Aflapin® Against Osteoarthritis of the Knee: A Double Blind, Randomized, Placebo Controlled Clinical Study"
... and tolerability of 5-L o xin ® and Aflapin ® in the treatment of OA of the knee. Materials and Methods Study materials BE-30 (5-L o x in ) is a novel Boswellia serrata ex- tract standardized ... Hematological and biochemical evaluations For assessment of safety of 5-Loxi n ® and Afla- pin ® , several parameters were evaluated in serum, urine and whole blood...
Ngày tải lên: 25/10/2012, 11:40
Tài liệu Báo cáo khoa học: Identification and characterization of the transcription factors involved in T-cell development, t-bet, stat6 and foxp3, within the zebrafish, Danio rerio docx
... tissue of mouse and spleen and thymus of human and mouse [11,37]. Foxp3 is also highly expressed in lymphoid organs, such as the thymus and spleen [49], and its expression within a variety of other ... the expression of these genes within humans and mice, of T-bet within Ginbuna crucian carp [27] and STAT6 in mandarin fish [28] have shown similar widespread expression....
Ngày tải lên: 16/02/2014, 09:20
Tài liệu Báo cáo khoa học: Molecular cloning and characterization of soybean protein disulfide isomerase family proteins with nonclassic active center motifs pdf
... S1. Comparison of intron–exon structures of GmPDIL-3a, GmPDIL-3b and orthologs of other plants. Fig. S2. Multiple amino acid sequence alignment of GmPDIL-3a, GmPDIL-3b and orthologs of other plants. Fig. ... Identification of the initiation codons in GmPDIL-3a and Gm-PDIL-3b mRNAs. (A) Schematic representation of the structure of GmPDIL-3a and GmPDIL-3b mRNAs. The putat...
Ngày tải lên: 18/02/2014, 11:20
Tài liệu Báo cáo khoa học: SREBPs: physiology and pathophysiology of the SREBP family ppt
... In particular, p21 is a direct target of SREBP [20]. The role of SREBP-1a in the regulation of cell growth and the cell cycle might be biphasic and complex, and needs to be further investigated. SREBP ... conditions of overnutrition, SREBP-1c expression is elevated, and consequently, the levels of nuclear SREBP-1c protein and lipogenesis are enhanced in the liver and adi...
Ngày tải lên: 18/02/2014, 13:20
Tài liệu Báo cáo khoa học: Identification and characterization of an R-Smad ortholog (SmSmad1B) from Schistosoma mansoni pdf
... Drosophila MAD and the vertebrate Smad1, Fig. 1. Structure of the SmSmad1B gene, cDNA and protein. (A) Schematic representations of the SmSmad1B gene, cDNA and protein and the amino acid sequence of SmSmad1B ... Fantappie 2 , Francisco M. B. Oliveira 2 and Philip T. LoVerde 1,2 1 Department of Microbiology and Immunology, School of Medicine and Biomedical Sciences, Sta...
Ngày tải lên: 18/02/2014, 16:20
Tài liệu Báo cáo khoa học: Topology, tinkering and evolution of the human transcription factor network doc
... cut-off k c . By using this algorithm, both hubs and connectors among hubs are retained. Acknowledgements Thanks to Dr J. Aldana-Montes and members of Kha- os group research of the University of ... in order of increasing degree in random webs [61]. Compared with pure random ER and SF networks, bio- molecular webs show the characteristic modular and hierar- chical organization...
Ngày tải lên: 19/02/2014, 07:20