Báo cáo khoa học: The crystal structure of the ring-hydroxylating dioxygenase from Sphingomonas CHY-1 pot
Báo cáo khoa học: MR solution structure of the precursor for carnobacteriocin B2, an antimicrobial peptide fromCarnobacterium piscicola Implications of the a-helical leader section for export and inhibition of type IIa bacteriocin activity pdf
... establish the preferred geometry of the precursor. We now report the chemical synthesis, bio- chemical production, and solution structure of preCbnB2, and compare it with the structure of the mature bacteriocin, ... Solution structure of preCbnB2 in 70% trifluoroethanol. The positions of the N-terminus and C-terminus are indicated, as are the residues at the s...
Ngày tải lên: 07/03/2014, 15:20
Báo cáo khoa học: Monomeric solution structure of the helicase-binding domain of Escherichia coli DnaG primase pdf
... Stereo views of the solution and crystal structures of DnaG-C. (A) Superposi- tion of the backbone atoms of residues 447–581 of the 20 NMR conformers of DnaG-C representing the NMR structure (Table ... and boundaries of helix 6 (Fig. 3D,E), showing that this helix can be separated from the core of the structure. The solution structure of DnaG-C identifi...
Ngày tải lên: 16/03/2014, 12:20
Báo cáo khoa học: X-ray structure of glucose/galactose receptor from Salmonella typhimurium in complex with the physiological ligand, (2R)-glyceryl-b-D-galactopyranoside pdf
... This kind of protein is exemplified by the Thermus thermophilus protein, PDB entry 2B3B [28]. The mode of binding the monosaccharide is completely different in terms of orientation of the sugar, ... similarity between the Fig. 3. Extension of the GGal site. Stereo- view of the residues lining the water-filled tunnel that extends from the glyceryl moiety to the...
Ngày tải lên: 23/03/2014, 04:21
Báo cáo khoa học: Change in structure of the N-terminal region of transthyretin produces change in affinity of transthyretin to T4 and T3 pdf
... evolution of the primary structure of the N-terminal regions of TTR and the biological function of TTR. Results Synthesis of recombinant human TTR In the crocodile, TTR is only synthesized in the liver during ... T4). In the other, the N-terminal region of crocTTR was deleted. The affinity of T3 and T4 to both TTRs was studied and the results are a powerful de...
Ngày tải lên: 23/03/2014, 10:21
Tài liệu Báo cáo khoa học: Salt-induced formation of the A-state of ferricytochrome c – effect of the anion charge on protein structure docx
... for the formation of the A-state from acid-denatured cytochrome c,as the A-state possesses a native-like a-helix structure [11,17]. Figure 1 shows the gradual recovery of the ordered secondary structure ... that the variants undergo very fast optical (and thus structural) changes within the dead time of the stopped-flow apparatus. In the case of the K13N mutan...
Ngày tải lên: 19/02/2014, 05:20
Báo cáo khoa học: NMR solution structure of Cn12, a novel peptide from the Mexican scorpion Centruroides noxius with a typical b-toxin sequence but with a-like physiological activity doc
... (E Na ¼ )65). To determine the amplitude of the toxin-induced slow inactivation, we subtracted the control traces from the traces recorded in the presence of the toxin. The amplitude of these toxin-induced ... a clear cut separation of all the b Na-ScTxs from all the a Na-ScTxs. The a Na-ScTxs have identities of the order of 50% among themselves, the sa...
Ngày tải lên: 23/03/2014, 12:20
Báo cáo khoa học: Three-dimensional structure of a thermostable native cellobiohydrolase, CBH IB, and molecular characterization of the cel7 gene from the filamentous fungus, Talaromyces emersonii ppt
... be accommodated. The b-sandwich represents the characteris- tic fold of GH7 and is a lso the fold of the l egume-lectin family and of GH16 [57]. The loops extending from the b-sandwich are stabilized by the ... hold the b-sandwich in position. With the exception of four a-helices and t wo pairs of short b-strands, the rest of the protein consists almost ent...
Ngày tải lên: 23/03/2014, 13:20
Báo cáo khoa học: H NMR study of the molecular structure and magnetic properties of the active site for the cyanomet complex of O2-avid hemoglobin from the trematode Paramphistomum epiclitum pdf
... away from the heme normal (z¢ axis), a is the angle between the projection of the tilt of the z axis on the x¢,y¢ plane (defined direction of tilt of z and the x¢ axis), and j % a + c defines the location ... ligand. Comparison of the strengths of dipolar interactions in solution with the alternate crystal structures of methemo- globin establish that the...
Ngày tải lên: 23/03/2014, 17:22
Báo cáo khoa học: Inhibitor-mediated stabilization of the conformational structure of a histone deacetylase-like amidohydrolase pptx
... refolding of HDAH The crystal structure of HDAH contains one Zn 2+ ion at the bottom of the active site and two K + ions in the neighbourhood of the active site [13]. The import- ance of Zn 2+ and ... interactions of the aliphatic chains with Phe152 and Phe208, are believed to con- tribute to the stabilization of the the major part of the conformational...
Ngày tải lên: 30/03/2014, 08:20
Tài liệu Báo cáo khoa học: An autoinhibitory effect of the homothorax domain of Meis2 ppt
... positions of molecular mass markers are shown to the left, and the size in base pairs of the products to the right (the Meis2 equivalent of Meis3.2 would be expected at 149 bp). (C, D) RNA from a series ... However, the activity of the full-length Meis1a was not tested, and on the basis of our work we expect that its activity would be inhibited by the conserved Ht...
Ngày tải lên: 16/02/2014, 15:20